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    • 1. 发明申请
    • Stable Colloidal Suspensions Of Gold Nanoconjugates And The Method For Preparing The Same
    • 金纳米结晶的稳定胶体悬浮液及其制备方法
    • US20130189793A1
    • 2013-07-25
    • US13744633
    • 2013-01-18
    • Wei QianYong Che
    • Wei QianYong Che
    • G01N21/64
    • G01N21/64A61K47/6923B01J13/0034B01J13/0043B82Y30/00G01N21/554
    • In the present invention, a method for determining the stability threshold amount of a stabilizer component for gold nanoparticles to prevent their aggregation in any electrolyte solution, is disclosed. The method permits for very low levels of stabilizer components to be used while still permitting conjugation with other functional ligands. The method comprises preparation of stable gold nanoparticles conjugated with different amount of stabilizing agents in deionized water first and then testing the stability of colloidal suspension of these gold nanoparticles in the presence of the electrolyte solution by monitoring the absorbance at 520 nm. The invention also comprises a method for fabrication of nanoconjugates comprising gold nanoparticles and only the stabilizer components or comprising gold nanoparticles, stabilizer components and functional ligands, which are stable in the presence of electrolytes.
    • 在本发明中,公开了一种用于确定金纳米颗粒的稳定剂组分以防止其在任何电解质溶液中聚集的稳定剂阈值量的方法。 该方法允许使用非常低水平的稳定剂组分,同时仍允许与其它官能配体缀合。 该方法首先制备在去离子水中与不同量的稳定剂缀合的稳定金纳米颗粒,然后通过监测520nm处的吸光度,测定这些金纳米粒子在电解质溶液存在下的胶体悬浮液的稳定性。 本发明还包括一种制造纳米缀合物的方法,其包括金纳米颗粒并且仅包含稳定剂组分或包含在电解质存在下稳定的金纳米颗粒,稳定剂组分和官能配体。
    • 4. 发明授权
    • Production of organic compound nanoparticles with high repetition rate ultrafast pulsed laser ablation in liquids
    • 在液体中生产具有高重复率超快速脉冲激光烧蚀的有机复合纳米粒子
    • US08992815B2
    • 2015-03-31
    • US12951496
    • 2010-11-22
    • Zhendong HuYong Che
    • Zhendong HuYong Che
    • B01J13/00B82Y40/00A61K9/14B23K26/06
    • A61K9/10A61K9/14A61K31/12B01J13/0086B23K26/0624B23K26/144B23K26/146B82Y40/00Y10S977/889Y10S977/901
    • Disclosed is a method of producing a chemically pure and stably dispersed organic nanoparticle colloidal suspension using an ultrafast pulsed laser ablation process. The method comprises irradiating a target of an organic compound material in contact with a poor solvent with ultrashort laser pulses at a high repetition rate and collecting the nanoparticles of the organic compound produced. The method may be implemented with a high repetition rate ultrafast pulsed laser source, an optical system for focusing and moving the pulsed laser beam, an organic compound target in contact with a poor solvent, and a solvent circulating system to cool the laser focal volume and collect the produced nanoparticle products. By controlling various laser parameters, and with optional poor solvent flow movement, the method provides stable colloids of dispersed organic nanoparticles in the poor solvent in the absence of any stabilizing agents.
    • 公开了使用超快脉冲激光烧蚀工艺制备化学纯的和稳定分散的有机纳米颗粒胶体悬浮液的方法。 该方法包括用高重复率的超短激光脉冲对与有害化合物接触的有机化合物材料进行照射,并收集生成的有机化合物的纳米颗粒。 该方法可以用高重复率超快脉冲激光源,用于聚焦和移动脉冲激光束的光学系统,与不良溶剂接触的有机化合物靶和溶剂循环系统来实现,以冷却激光焦点体积和 收集生产的纳米颗粒产品。 通过控制各种激光参数,并且具有可选的不良溶剂流动运动,该方法在不存在任何稳定剂的情况下在不良溶剂中提供分散的有机纳米颗粒的稳定胶体。
    • 8. 发明申请
    • PULSED LASER MICRO-DEPOSITION PATTERN FORMATION
    • 脉冲激光微沉积图形成
    • US20100227133A1
    • 2010-09-09
    • US12400438
    • 2009-03-09
    • Bing LiuZhendong HuMakoto MurakamiJingzhou XuYong Che
    • Bing LiuZhendong HuMakoto MurakamiJingzhou XuYong Che
    • B32B3/00C23C14/34C23C14/00
    • C23C20/04B41M5/262B41M5/267B44F1/10C23C14/28C23C14/3435G02B26/101Y10T428/24802Y10T428/24917
    • A method of forming patterns on transparent substrates using a pulsed laser is disclosed. Various embodiments include an ultrashort pulsed laser, a substrate that is transparent to the laser wavelength, and a target plate. The laser beam is guided through the transparent substrate and focused on the target surface. The target material is ablated by the laser and is deposited on the opposite substrate surface. A pattern, for example a gray scale image, is formed by scanning the laser beam relative to the target. Variations of the laser beam scan speed and scan line density control the material deposition and change the optical properties of the deposited patterns, creating a visual effect of gray scale. In some embodiments patterns may be formed on a portion of a microelectronic device during a fabrication process. In some embodiments high repetition rate picoseconds and nanosecond sources are configured to produce the patterns.
    • 公开了使用脉冲激光在透明基板上形成图案的方法。 各种实施例包括超短脉冲激光器,对激光波长透明的衬底和靶板。 激光束被引导通过透明基板并聚焦在目标表面上。 目标材料被激光烧蚀并沉积在相对的基板表面上。 通过相对于目标扫描激光束来形成例如灰度图像的图案。 激光束扫描速度和扫描线密度的变化控制材料沉积并改变沉积图案的光学性质,产生灰度的视觉效果。 在一些实施例中,可以在制造过程期间在微电子器件的一部分上形成图案。 在一些实施例中,高重复率皮秒和纳秒源被配置为产生图案。