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1. 发明授权

US06390993B1 Guidewire having linear change in stiffness 有权
标题翻译：导丝具有刚度线性变化
公开(公告)号：US06390993B1
公开(公告)日：2002-05-21
申请号：US09203140
申请日：1998-12-01
申请人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark Richardson
发明人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark Richardson
IPC分类号： A61B500
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.
摘要翻译：本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度线性变化的设备。该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该轮廓优选被配置成在装置的纵向部分上产生芯的刚度的线性变化。

2. 发明授权

US06666829B2 Guidewire having linear change in stiffness 有权
公开(公告)号：US06666829B2
公开(公告)日：2003-12-23
申请号：US09881290
申请日：2001-06-12
申请人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark Richardson , Kent C. Stalker , Olin J. Palmer
发明人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark Richardson , Kent C. Stalker , Olin J. Palmer
IPC分类号： A61B500
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.

3. 发明申请

US20110230840A1 GUIDEWIRE HAVING LINEAR CHANGE IN STIFFNESS 有权
标题翻译：具有线性变化的GUIDEWIRE
公开(公告)号：US20110230840A1
公开(公告)日：2011-09-22
申请号：US13150973
申请日：2011-06-01
申请人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. Stalker , Olin J. Palmer
发明人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. Stalker , Olin J. Palmer
IPC分类号： A61M25/09
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.
摘要翻译：本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度线性变化的设备。该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该轮廓优选被配置成在装置的纵向部分上产生芯的刚度的线性变化。

4. 发明申请

US20080146967A1 Polymer coated guidewire 有权
标题翻译：聚合物涂层导丝
公开(公告)号：US20080146967A1
公开(公告)日：2008-06-19
申请号：US10631275
申请日：2003-07-31
申请人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
发明人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
IPC分类号： A61M25/00
CPC分类号： A61L31/10 , A61L31/18 , A61M25/0045 , A61M25/0054 , A61M25/09 , A61M2025/09083 , A61M2025/09133 , A61M2025/09166
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under fluoroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间断的，连续的或呈螺旋状的形式，用于在透视成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

5. 发明授权

US06673025B1 Polymer coated guidewire 有权
标题翻译：聚合物涂层导丝
公开(公告)号：US06673025B1
公开(公告)日：2004-01-06
申请号：US09441698
申请日：1999-11-16
申请人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
发明人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
IPC分类号： A61B500
CPC分类号： A61M25/09 , A61M2025/09175
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under flouroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间歇的，连续的或以螺旋带的形式，用于在荧光成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

6. 发明授权

US07878985B2 Guidewire having linear change in stiffness 有权
标题翻译：导丝具有刚度线性变化
公开(公告)号：US07878985B2
公开(公告)日：2011-02-01
申请号：US10659930
申请日：2003-09-11
申请人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. Stalker , Olin J. Palmer
发明人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. Stalker , Olin J. Palmer
IPC分类号： A61B5/00
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.
摘要翻译：本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯部件，该芯部件具有多个相邻的锥形部分，该锥形部分具有锥形角度，该锥形角度构造成在该装置的纵向部分上产生刚度线性变化。该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该轮廓优选被配置成在装置的纵向部分上产生芯的刚度的线性变化。

7. 发明授权

US07455646B2 Polymer coated guide wire 有权
标题翻译：聚合物涂层导丝
公开(公告)号：US07455646B2
公开(公告)日：2008-11-25
申请号：US11768794
申请日：2007-06-26
申请人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
发明人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
IPC分类号： A61B5/00 , A61M25/00
CPC分类号： A61M25/09 , A61L31/10 , A61L31/18 , A61M25/0045 , A61M25/0054 , A61M2025/09083 , A61M2025/09133 , A61M2025/09166
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under flouroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间歇的，连续的或以螺旋带的形式，用于在荧光成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

8. 发明申请

US20090062773A1 GUIDEWIRE HAVING LINEAR CHANGE IN STIFFNESS 有权
标题翻译：具有线性变化的GUIDEWIRE
公开(公告)号：US20090062773A1
公开(公告)日：2009-03-05
申请号：US12047008
申请日：2008-03-12
申请人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. Stalker , Olin J. Palmer
发明人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. Stalker , Olin J. Palmer
IPC分类号： A61M25/09
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.
摘要翻译：本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度的线性变化的设备。该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该曲线轮廓优选地被配置为在装置的纵向部分上产生芯的刚度的线性变化。

9. 发明授权

US07494474B2 Polymer coated guidewire 有权
标题翻译：聚合物涂层导丝
公开(公告)号：US07494474B2
公开(公告)日：2009-02-24
申请号：US10631275
申请日：2003-07-31
申请人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
发明人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
IPC分类号： A61B5/00 , A61M25/00
CPC分类号： A61L31/10 , A61L31/18 , A61M25/0045 , A61M25/0054 , A61M25/09 , A61M2025/09083 , A61M2025/09133 , A61M2025/09166
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under fluoroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间断的，连续的或呈螺旋状的形式，用于在透视成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

10. 发明授权

US06652472B2 Guidewire with smoothly tapered segment 有权
公开(公告)号：US06652472B2
公开(公告)日：2003-11-25
申请号：US10186858
申请日：2002-07-01
申请人： Mo Jafari , Sepehr Fariabi , Lawrence E. Brennan , Wayne E. Cornish , Marc M. Jalisi , David M. Anderson
发明人： Mo Jafari , Sepehr Fariabi , Lawrence E. Brennan , Wayne E. Cornish , Marc M. Jalisi , David M. Anderson
IPC分类号： A61B500
CPC分类号： A61M25/09 , A61M2025/09175
摘要： A guidewire for intraluminal advancement of a medical device within a patient which has an elongate core member with a flexible body member disposed on a distal section thereof. In one embodiment, the distal section of the elongate core member has at least one flexible segment with at least one pair of opposed tapered or parallel faces. Preferably the flexible segment with the tapered or parallel faces is disposed at the distal end of the elongate core and forms a shapable segment.

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