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    • 4. 发明申请
    • SIRE EARLY SELECTION FOR MALE FERTILITY USING SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) OF THE DAZL GENE
    • 使用DAZL基因的单核苷酸多态性(SNPS)的SIRE早期选择雄性不育
    • US20100009374A1
    • 2010-01-14
    • US12522916
    • 2008-01-11
    • Wansheng LiuAihua Wang
    • Wansheng LiuAihua Wang
    • C12Q1/68
    • C12Q1/6883C12Q2600/106
    • Methods and materials for identifying bovine males which will produce semen which will exhibit a higher rate of successfully impregnation by either artificial insemination or natural mating. The method employs SNPs that have been identified in the bDAZL gene which are associated with enhanced (or decreased) male fertility in bovine males and haplotypes formed from such SNPs. The method herein can be used to identify male dairy or beef cattle. The method herein can be applied to bovine animals at an appropriate time and particularly at birth or in utero. The invention further provides kits for conduction assays to assess bovine male fertility/infertility. The invention additionally provides a method of breeding cattle employing the methods and materials herein.
    • 用于鉴定将产生精液的牛男性的方法和材料,其将通过人工授精或天然交配显示更高的成功浸渍率。 该方法使用已经在bDAZL基因中鉴定的SNP,其与由这些SNP形成的牛雄性和单元型的雄性生育力增强(或降低)相关。 本方法可用于鉴定男性乳牛或肉牛。 本文的方法可以在适当的时间,特别是在出生时或在子宫内应用于牛动物。 本发明进一步提供用于评估牛雄性生育力/不孕症的传导测定的试剂盒。 本发明另外提供了使用本文的方法和材料来养殖牛的方法。