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1. 发明申请

US20050054953A1 Double ended wire guide 有权
标题翻译：双端导线
公开(公告)号：US20050054953A1
公开(公告)日：2005-03-10
申请号：US10934927
申请日：2004-09-03
申请人： Walter Ryan , Frank Fischer , Thomas Foster , Gary Butler
发明人： Walter Ryan , Frank Fischer , Thomas Foster , Gary Butler
IPC分类号： A61B5/00 , A61M25/00 , A61M25/09 , B21F45/00
CPC分类号： A61M25/09 , A61M2025/09091 , A61M2025/09108 , A61M2025/09133 , A61M2025/09175 , Y10T29/49826
摘要： Double ended wire guides are manufactured so that either end, or both ends sequentially, may be inserted into a patient. The ends are different, so that the inventory requirements of wire guides are minimized. For example, a wire guide may have a straight end and an angled end, either end suitable for use on the patient. The wire guides may also differ in other characteristics, such as the stiffness or the diameters of the distal and proximal portions. The wire guide may also be stored in a package, the package including a fitting so that wetting solution may be injected into the package to wet the wire guide and prepare it for use.
摘要翻译：制造双端导线器，使得任一端或两端依次插入患者体内。端部是不同的，使得导线器的库存要求最小化。例如，线引导件可以具有直的端部和成角度的端部，任一端部适于在患者身上使用。线引导件也可以在其它特征方面不同，例如远侧和近端部分的刚度或直径。电线引导件也可以存储在包装中，包装件包括配件，使得润湿溶液可以注入到包装中以润湿导线器并使其准备使用。

2. 发明申请

US20050192592A1 Self-tensioning handle for endoscopic device 审中-公开
标题翻译：内窥镜装置自张力手柄
公开(公告)号：US20050192592A1
公开(公告)日：2005-09-01
申请号：US11065220
申请日：2005-02-24
申请人： Gary Butler , Thomas Foster , Frank Fischer , Nicholas Terwiske , John Ward , Richard Stamper , David Radue , Elizabeth Purdy , Robert Davignon , Barry Davignon , Ronald Hofmann
发明人： Gary Butler , Thomas Foster , Frank Fischer , Nicholas Terwiske , John Ward , Richard Stamper , David Radue , Elizabeth Purdy , Robert Davignon , Barry Davignon , Ronald Hofmann
IPC分类号： A61B17/00 , A61B17/22 , A61B17/24 , A61B17/28
CPC分类号： A61B17/2909 , A61B17/221 , A61B2017/00424 , A61B2017/2212 , A61B2017/2918 , A61B2017/292
摘要： A self-tensioning handle for use with endoscopic devices is disclosed. The handle may have mounting features for mounting a sheath and a control rod from an endoscopic device, such as a grasper or a retrieval basket. One mounting feature, such as a pin vise to hold a sheath, may be mounted in a distal portion of the handle, nearer a patient. Another mounting feature for a control rod or cannula of the endoscopic device is preferably mounted in a proximal portion of the handle. The handle is assembled with a tension or a pre-load so that a surgeon is not required to continually grip and compress the handle to retain a sample in the retrieval basket or other end-effector used with the handle.
摘要翻译：公开了一种用于内窥镜装置的自张紧手柄。手柄可以具有用于从内窥镜装置（例如抓紧器或取出篮）安装护套和控制杆的安装特征。一个安装特征，例如用于保持护套的针脚，可以安装在手柄的远侧部分中，更靠近患者。内窥镜装置的控制杆或插管的另一安装特征优选地安装在手柄的近端部分中。手柄以张力或预加载组装，使得外科医生不需要持续地握持和压缩手柄以将样品保持在与手柄一起使用的回收篮或其它末端执行器中。

3. 发明申请

US20050137585A1 Back loading endoscopic instruments 审中-公开
标题翻译：背装内窥镜仪器
公开(公告)号：US20050137585A1
公开(公告)日：2005-06-23
申请号：US11020328
申请日：2004-12-22
申请人： Jamie Landman , Walter Ryan , Troy Wingler , Thomas Foster
发明人： Jamie Landman , Walter Ryan , Troy Wingler , Thomas Foster
IPC分类号： A61B10/00 , A61B10/06 , A61B17/00 , A61B17/28
CPC分类号： A61B10/06 , A61B17/00234 , A61B2017/0046 , A61B2017/2905 , A61B2017/2933 , A61B2017/2937
摘要： A back loading instrument for use with a medical device, such as an endoscope or a colonoscope, features larger endoscopic instruments or end effectors and enables gathering of much larger samples, such as biopsies. The instrument also allows for superior grasping, mobilization, cutting, or removal of tissue or foreign bodies from a patient. The end effector, such as a biopsy forceps, of the back loading instrument has a cross-sectional area larger than that of the working channel of the endoscope or other medical device used to control the instrument. By using this medical device as part of a minimally-invasive procedure, trauma to the patient is minimized.
摘要翻译：用于与诸如内窥镜或结肠镜的医疗装置一起使用的后背装置具有更大的内窥镜器械或末端执行器，并且能够收集更大的样品，例如活组织检查。该仪器还允许从患者中优良的抓握，动员，切割或去除组织或异物。背部装载器具的末端执行器（例如活检钳）的横截面面积大于用于控制仪器的内窥镜或其他医疗装置的工作通道的横截面面积。通过使用该医疗装置作为微创手术的一部分，对患者的创伤被最小化。

4. 发明申请

US20070255256A1 Irrigation Catheter 审中-公开
标题翻译：灌溉导管
公开(公告)号：US20070255256A1
公开(公告)日：2007-11-01
申请号：US11547537
申请日：2005-03-24
申请人： Frank Fischer , Thomas Foster , Tracy Willis
发明人： Frank Fischer , Thomas Foster , Tracy Willis
IPC分类号： A61M25/00
CPC分类号： A61M25/003 , A61M3/0283 , A61M25/0032 , A61M25/0068 , A61M25/007 , A61M25/0071 , A61M25/008 , A61M2025/0073
摘要： An irrigation catheter having at least two lumens for supplying irrigation fluid in minimally-invasive surgical procedures is revealed. The catheter works alongside but independently of an endoscope or other diagnostic or therapeutic instrument. The catheter may direct flow of the irrigation fluid in the same direction as the body's natural flow, thus enhancing visualization by the endoscope or other instrument.
摘要翻译：揭示了具有至少两个腔的灌洗导管，用于在微创外科手术中提供冲洗液。导管与内窥镜或其他诊断或治疗仪器一起工作，但是独立于内窥镜或其他诊断或治疗仪器。导管可以引导冲洗流体沿与身体的自然流动相同的方向流动，从而增强内窥镜或其他器械的可视化。

5. 发明授权

US08961471B2 Syringe device, system and method for delivering ozone gas 有权
标题翻译：注射装置，用于输送臭氧气体的系统和方法
公开(公告)号：US08961471B2
公开(公告)日：2015-02-24
申请号：US12000374
申请日：2007-12-12
申请人： David M. Hooper , Thomas Foster , Noel Henson
发明人： David M. Hooper , Thomas Foster , Noel Henson
IPC分类号： A61M5/32 , A61M37/00 , A61M5/00 , A61M5/315 , A61M39/16 , A61M5/31 , C01B13/11
CPC分类号： A61M5/002 , A61K9/0019 , A61K33/00 , A61M5/001 , A61M5/3129 , A61M39/16 , A61M2005/006 , A61M2005/3117 , A61M2039/167 , A61M2202/0216 , A61M2205/7536 , A61M2209/06 , C01B13/11 , C01B13/115 , C01B2201/10 , C01B2201/64
摘要： In accordance with at least one exemplary embodiment, a syringe device, a method and a system for delivering a therapeutic amount of ozone are disclosed. A sterility case can enclose a syringe portion and can maintain sterility while the syringe device is interfaced to an ozone generator. A valvably-controlled fluid channel can extend from a barrel of the syringe portion through the case. Conducting elements can be attached to the case and can breach the case. The conductive elements can be connected to electrodes. The electrodes can be attached to the syringe portion. The syringe portion can be filled with oxygen gas via the valvably-controlled fluid channel. An electric current can be provided to the conductive elements from the ozone generator resulting in a corona discharge from at least one of the electrodes. The therapeutic amount of ozone can be produced from the oxygen gas and the syringe portion delivered into a sterile field without compromise.
摘要翻译：根据至少一个示例性实施例，公开了一种用于输送治疗量的臭氧的注射器装置，方法和系统。无菌情况可以包围注射器部分，并且可以在注射器装置与臭氧发生器连接时保持不育。可控制的流体通道可以从注射器部分的筒体延伸通过壳体。传导元件可以附在案件上，并可以违反案件。导电元件可以连接到电极。电极可以附接到注射器部分。注射器部分可以通过可调节控制的流体通道填充氧气。可以从臭氧发生器向导电元件提供电流，从而从至少一个电极进行电晕放电。可以从氧气和注射器部分产生处理量的臭氧，而不损害地将其输送到无菌区域中。

6. 发明授权

US07739056B2 Biomarkers for aging 失效
标题翻译：生物标志物老化
公开(公告)号：US07739056B2
公开(公告)日：2010-06-15
申请号：US12379520
申请日：2009-02-24
申请人： Philip Landfield , Eric Blalock , Kuey-Chu Chen , Thomas Foster
发明人： Philip Landfield , Eric Blalock , Kuey-Chu Chen , Thomas Foster
IPC分类号： G06F7/00
CPC分类号： C12Q1/6809 , C12Q1/6883 , C12Q2600/158 , G06F19/18 , G06F19/28
摘要： A statistical and functional correlation strategy to identify changes in cellular pathways specifically linked to impaired cognitive function with aging. Analyses using the strategy identified multiple groups of genes expressed in the hippocampi of mammals, where the genes were expressed at different levels for several ages. The aging changes in expression began before mid-life. Many of the genes were involved in specific neuronal and glial pathways with previously unrecognized relationships to aging and/or cognitive decline. These identified genes and the proteins they encode can be used as novel biomarkers of brain aging and as targets for developing treatment methods against age-related cognitive decline, Alzheimer's Disease and Parkinson's Disease.
摘要翻译：一种统计和功能相关策略，用于识别与衰老的认知功能特异性相关的细胞途径的变化。使用该策略分析确定哺乳动物海马中表达的多组基因，其中基因在不同水平上表达数个年龄。老龄化的变化开始于中年之前。许多基因参与特定的神经元和神经胶质细胞通路，其中以前未被认识到与衰老和/或认知衰退的关系。这些鉴定的基因及其编码的蛋白质可用作脑老化的新生物标志物，并用作开发针对年龄相关认知衰退，阿尔茨海默病和帕金森病的治疗方法的目标。

7. 发明申请

US20050219583A1 Post rip image rendering for image alignment 审中-公开
标题翻译： Post rip图像渲染用于图像对齐
公开(公告)号：US20050219583A1
公开(公告)日：2005-10-06
申请号：US11082640
申请日：2005-03-17
申请人： Thomas Foster , Gregory Rombola
发明人： Thomas Foster , Gregory Rombola
IPC分类号： G06F15/00 , G06K15/00 , G06K15/12
CPC分类号： G06K15/12
摘要： A method of printing an image comprising the steps of converting the image into a digital bitmap comprised of an array of pixels wherein each pixel is assigned a digital value representing marking information, identifying a first edge of a first character, identifying a second edge of a second character and, reassigning the digital value(s) pixel(s) adjacent to the first edge and/or the second edge in order for the first edge to appear contiguous with the second edge.
摘要翻译：一种打印图像的方法，包括以下步骤：将图像转换成由像素阵列组成的数字位图，其中每个像素分配有表示标记信息的数字值，识别第一个字符的第一个边缘，第二字符，并且重新分配与第一边缘和/或第二边缘相邻的数字值像素，以使第一边缘显示为与第二边缘邻接。

8. 发明申请

US20050110994A1 Method for operating a laser scanning confocal microscope system and a system thereof 失效
公开(公告)号：US20050110994A1
公开(公告)日：2005-05-26
申请号：US11014820
申请日：2004-12-20
申请人： Thomas Foster , David Conover , Chad Biglow , Irene Georgakoudi , Andrey Mezhiba , Soumya Mitra
发明人： Thomas Foster , David Conover , Chad Biglow , Irene Georgakoudi , Andrey Mezhiba , Soumya Mitra
IPC分类号： G02B21/00 , G01N21/64
CPC分类号： G02B21/0076 , G02B21/0024
摘要： A method for operating a confocal microscope system includes deflecting a light beam on a specimen with at least one beam deflection device. The position of the light beam is stepped with at least one beam deflection device across the specimen. A sample of emitted fluorescent light from the specimen is captured in synchronization with each of the stepped positions of the light beam. An image is obtained from the captured samples of emitted fluorescent light.

9. 发明申请

US20090221921A1 SIDE-FIRING LINEAR FIBER OPTIC ARRAY FOR INTERSTITIAL OPTICAL THERAPY AND MONITORING USING COMPACT HELICAL GEOMETRY 审中-公开
标题翻译：用于间断光学治疗的边缘线性光纤阵列和使用紧凑的螺旋形几何测量
公开(公告)号：US20090221921A1
公开(公告)日：2009-09-03
申请号：US12296886
申请日：2007-04-09
申请人： William J. Cottrell , Thomas Foster
发明人： William J. Cottrell , Thomas Foster
IPC分类号： A61B6/00 , A61B18/22 , A61N5/067
CPC分类号： A61B18/22 , A61B5/0071 , A61B5/0075 , A61B18/24 , A61B2018/1807 , A61B2018/2216 , A61N5/0601 , A61N5/062 , A61N2005/0662 , A61N2005/067 , G02B6/06
摘要： An optical probe has multiple side-firing optical fibers which terminate in a linearly staggered fashion. A central fiber can be used as well. In diagnostic techniques, one fiber can be used as an emitter, while the others are used as receivers, or various fibers can be used as emitters and receivers at different times to form a map of the area. In therapeutic techniques, the treatment light can be emitted from the fibers in parallel or in sequence, and the fluence can be independently adjusted for each of the fibers.
摘要翻译：光学探针具有以线性交错方式终止的多个侧射光纤。也可以使用中心纤维。在诊断技术中，一根光纤可以用作发射器，而其他光纤可以用作接收器，或者各种光纤可以在不同时间用作发射器和接收器，以形成该区域的映射。在治疗技术中，处理光可以从纤维平行或顺序发射，并且可以针对每个纤维独立地调节注量。

10. 发明申请

US20070137694A1 Notch filter for triple junction solar cells 有权
标题翻译：三结太阳能电池的陷波滤波器
公开(公告)号：US20070137694A1
公开(公告)日：2007-06-21
申请号：US11305434
申请日：2005-12-16
申请人： Thomas Foster , James Snyder
发明人： Thomas Foster , James Snyder
IPC分类号： H01L31/00
CPC分类号： H01L31/052 , H01L31/02168 , H01L31/0687 , Y02E10/544
摘要： A solar cell and method for producing same is disclosed. The solar cell includes a multijunction solar cell structure and a notch filter designed to reflect solar energy that does not contribute to the current output of the multijunction solar cell. By reflecting unused solar energy, the notch filter allows the solar cell to run cooler (and thus more efficiently) yet it still allows all junctions to fully realize their electrical current production capability.
摘要翻译：公开了一种太阳能电池及其制造方法。太阳能电池包括多结太阳能电池结构和陷波滤波器，其设计成反射对多结太阳能电池的电流输出无贡献的太阳能。通过反射未使用的太阳能，陷波滤波器允许太阳能电池运行更冷（并因此更有效率），但仍然允许所有连接点完全实现其电流产生能力。

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