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1. 发明授权

US5282856A Implantable prosthetic device 失效
标题翻译：植入式假体装置
公开(公告)号：US5282856A
公开(公告)日：1994-02-01
申请号：US137871
申请日：1987-12-22
申请人： Walter J. Ledergerber
发明人： Walter J. Ledergerber
IPC分类号： A61F2/00 , A61F2/12 , A61L27/34
CPC分类号： A61F2/12 , A61F2/0077 , A61L27/34
摘要： An implant and coverings for an implant for used in the human body are disclosed. Coverings for implants are constructed to present a biocompatible surface to the body and to provide a textured surface which serves to disorganize scar tissue which forms around the implant. Filaments of expanded PTFEe are attached to a stretch fabric backing in a loose weave configuration. Silicone molded in geometric patterns may be employed to present a textured surface. Compressive structures may be beneficially used on the surface of the implant or in the interior of the implant. Foam is one such compressive structure. Hexagonally shaped compressive cells containing fluid, gas, gel or foam are adapted to receive an insert which contains an outer biocompatible coating. A valve or port is provided to communicate between the cell and the body. Expansions means may be provided to expand the implant in a desired direction.
摘要翻译：公开了一种用于人体植入物的植入物和覆盖物。用于植入物的覆盖物构造成向身体提供生物相容性表面并提供纹理化表面，其用于混合在植入物周围形成的瘢痕组织。膨胀PTFEe的长丝以松散的织造结构附着在拉伸织物背衬上。可以使用以几何图案模制的硅树脂呈现纹理表面。压缩结构可有利地用于植入物的表面或植入物的内部。泡沫是一种这样的压缩结构。包含流体，气体，凝胶或泡沫的六边形压缩细胞适于接收包含外部生物相容性涂层的插入物。提供阀或端口以在电池和主体之间连通。可以提供扩展装置以在期望的方向上扩展植入物。

2. 发明授权

US09205238B2 Method of manufacturing for a seroma drainage device including micro-textured scar inducing ePTFE structures 有权
标题翻译：包括微纹理瘢痕诱导ePTFE结构的血清肿引流装置的制造方法
公开(公告)号：US09205238B2
公开(公告)日：2015-12-08
申请号：US14283849
申请日：2014-05-21
申请人： Walter J. Ledergerber
发明人： Walter J. Ledergerber
IPC分类号： A61M27/00 , B29C59/02 , A61F2/00 , A61F2/12 , A61L27/50 , A61L29/04 , A61F2/06
CPC分类号： A61M27/002 , A61F2/0077 , A61F2/06 , A61F2/064 , A61F2/12 , A61F2002/0086 , A61L27/50 , A61L29/041 , A61L2400/18 , A61L2430/04 , B29C59/02 , B29C59/021 , B29C2059/027 , B29C2791/009 , C08L27/18
摘要： Bio-implantable textured tubular and sheet structures of un-sintered ePTFE are described. Such micro-textured structures stimulate robust development of beneficial bio-integative scar attachment to adnexal soft tissues. Methods for texturing one side of an un-sintered extruded ePTFE tube or sheet are also described. A select length of tubing of any thickness or diameter is applied over a matching mandrel and adhesively stabilized thereon by applying intense suction. The texture is made by “RIGDA tooling” into the wall thickness of the material and by removing undesired material by distraction and avulsion tooling and methods assisted by vibration, leaving intact the finished product. Disclosed is an implantable, non-attached, enveloping, conforming and supportive drainage cover for breast and other soft implants. The drainage cover has numerous through and through cut lucencies which allow for liberal ingress and egress of interstitial biologic fluids enabling efficient drainage postoperatively, especially under the influence of active wound suction.
摘要翻译：描述了未烧结的ePTFE的生物可植入织构的管状和片状结构。这种微纹理结构刺激了有益的生物整合性瘢痕附着到附属软组织的强力发展。还描述了未烧结的挤压ePTFE管或片的一侧的纹理化方法。任何厚度或直径的选择长度的管道施加在匹配的心轴上并通过施加强吸力而在其上粘合地稳定。纹理由“RIGDA模具”制成材料的壁厚，并通过分散和撕脱模具以及通过振动辅助的方法去除不需要的材料，使成品完好无损。公开了一种用于乳房和其他软植入物的可植入，非附着，包封，一致和支持的排水罩。排水罩具有许多通过和通过切割的清晰度，其允许间隙生物液体的自由进入和排出，使得能够在术后有效排出，特别是在主动伤口吸引的影响下。

3. 发明授权

US08765039B1 Implantable micro-textured scar inducing ePTFE structures 失效
标题翻译：植入式微纹理瘢痕诱导ePTFE结构
公开(公告)号：US08765039B1
公开(公告)日：2014-07-01
申请号：US13275018
申请日：2011-10-17
申请人： Walter J. Ledergerber
发明人： Walter J. Ledergerber
IPC分类号： B29C65/02 , B29C59/02 , A61F2/06
CPC分类号： A61M27/002 , A61F2/0077 , A61F2/06 , A61F2/064 , A61F2/12 , A61F2002/0086 , A61L27/50 , A61L29/041 , A61L2400/18 , A61L2430/04 , B29C59/02 , B29C59/021 , B29C2059/027 , B29C2791/009 , C08L27/18
摘要： Bio-implantable textured tubular and sheet structures of un-sintered ePTFE are described. Such micro-textured structures stimulate robust development of beneficial bio-integrative scar attachment to adnexal soft tissues. Methods for texturing one side of an un-sintered extruded ePTFE tube or sheet are also described. A select length of tubing of any thickness or diameter is applied over a matching mandrel and adhesively stabilized thereon by applying intense suction. The texture is made by “RIGDA tooling” into the wall thickness of the material and by removing undesired material by distraction and avulsion tooling and methods assisted by vibration, leaving intact the finished product. Disclosed is an implantable, non-attached, enveloping, conforming and supportive drainage cover for breast and other soft implants. The drainage cover has numerous through and through cut lucencies which allow for liberal ingress and egress of interstitial biologic fluids enabling efficient drainage postoperatively, especially under the influence of active wound suction.
摘要翻译：描述了未烧结的ePTFE的生物可植入织构的管状和片状结构。这种微纹理结构刺激了有益的生物整合性瘢痕附着到附属软组织的强大发展。还描述了未烧结的挤压ePTFE管或片的一侧的纹理化方法。任何厚度或直径的选择长度的管道施加在匹配的心轴上并通过施加强吸力而在其上粘合地稳定。纹理由“RIGDA模具”制成材料的壁厚，并通过分散和撕脱模具以及通过振动辅助的方法去除不需要的材料，使成品完好无损。公开了一种用于乳房和其他软植入物的可植入，非附着，包封，一致和支持的排水罩。排水罩具有许多通过和通过切割的清晰度，其允许间隙生物液体的自由进入和排出，使得能够在术后有效排出，特别是在主动伤口吸引的影响下。

4. 发明授权

US06187043B1 Implantable prosthetic device 失效
标题翻译：植入式假体装置
公开(公告)号：US06187043B1
公开(公告)日：2001-02-13
申请号：US08955866
申请日：1997-10-21
申请人： Walter J. Ledergerber
发明人： Walter J. Ledergerber
IPC分类号： A61F212
CPC分类号： A61F2/12 , A61F2/0077 , A61L27/34 , C08L83/04 , C08L75/04 , C08L27/18
摘要： An implant and coverings for an implant for use in the human body are disclosed. Coverings for implants are constructed to present a biocompatible surface to the body and to provide a textured surface which serves to disorganize scar tissue which forms around the implant. Filaments of expanded PTFEe are attached to a stretch fabric backing in a loose weave configuration. Silicone molded in geometric patterns may be employed to present a textured surface. Compressive structures may be beneficially used on the surface of the implant or in the interior of the implant. Foam is one such compressive structure. Hexagonally shaped compressive cells containing fluid, gas, gel or foam are adapted to receive an insert which contains an outer biocompatible coating. A valve or port is provided to communicate between the cell and the body. Expansion means may be provided to expand the implant in a desired direction.
摘要翻译：公开了一种用于人体植入物的植入物和覆盖物。用于植入物的覆盖物构造成向身体提供生物相容性表面并提供纹理化表面，其用于混合在植入物周围形成的瘢痕组织。膨胀PTFEe的长丝以松散的织造结构附着在拉伸织物背衬上。可以使用以几何图案模制的硅树脂呈现纹理表面。压缩结构可有利地用于植入物的表面或植入物的内部。泡沫是一种这样的压缩结构。包含流体，气体，凝胶或泡沫的六边形压缩细胞适于接收包含外部生物相容性涂层的插入物。提供阀或端口以在电池和主体之间连通。可以提供扩展装置以沿期望的方向扩展植入物。

5. 发明授权

US08764824B2 Modulating buttress saline mammary prosthesis including limpet fill port 失效
标题翻译：调节支柱盐水乳房假体，包括痰液填充口
公开(公告)号：US08764824B2
公开(公告)日：2014-07-01
申请号：US13523017
申请日：2012-06-14
申请人： Walter J. Ledergerber
发明人： Walter J. Ledergerber
IPC分类号： A61F2/12
CPC分类号： A61F2/12
摘要： An implantable mammary prosthesis includes a limpet buttress fill port structure. The fill port structure preferably comprises a shell, the shell including an opening, a compartment interior to the shell adapted to contain a filler. The limpet buttress is generally cup-shaped, and is disposed within the shell. The limpet buttress is preferably attached to the shell adjacent the opening to form a fluidic seal, optionally via a sealing flange. The limpet buttress may include one or more ribs, such as to provide structural support to the limpet buttress. Preferably, a reservoir is disposed external to the shell.
摘要翻译：可植入的乳房假体包括一个悬臂支撑填充口结构。填充口结构优选地包括壳体，壳体包括开口，适于容纳填料的壳体的隔室内部。坠落的扶壁通常是杯形的，并且设置在外壳内。优选地，所述悬臂支撑件附接到邻近开口的壳体，以形成流体密封，任选地经由密封凸缘。悬臂支撑件可以包括一个或多个肋，例如为悬臂支撑提供结构支撑。优选地，储存器设置在外壳的外部。

6. 发明授权

US08202316B2 Modulating buttress saline mammary prosthesis 有权
标题翻译：调制支柱盐水乳房假体
公开(公告)号：US08202316B2
公开(公告)日：2012-06-19
申请号：US12360979
申请日：2009-01-28
申请人： Walter J. Ledergerber
发明人： Walter J. Ledergerber
IPC分类号： A61F2/12
CPC分类号： A61F2/12
摘要： A saline-filled breast prosthesis has enhanced performance by virtue of having tactile characteristics approximating those of gel-filled implants. The invention retains all the benefits of the recognized safety profile, straight-forward construction, and broad clinical indications for saline implants. An enhanced implantable mammary prosthesis comprises a shell, a slurry filler compartment interior to the shell containing slurry filler, a fluid compartment, the fluid compartment being deformable from a neutral profile under pressure from the slurry filler and which recoils to the neutral profile when not under pressure, a reservoir, the reservoir being disposed external to the shell, the reservoir and fluid compartment being fluidically coupled by a port, and a limiting membrane region disposed between the fluid compartment and the reservoir.
摘要翻译：由于具有接近凝胶填充种植体的触觉特性，充满盐水的乳房假体具有增强的性能。本发明保留了公认的安全性，直接施工和盐水植入物的广泛临床适应症的所有益处。增强的可植入乳房假体包括壳体，在包含浆料填充物的壳体内部的浆料填充剂隔室，流体隔室，流体室可在来自浆料填充物的压力下从中性轮廓变形，并且当不在下面时回弹到中性轮廓压力，储存器，储存器设置在外壳的外部，储存器和流体隔室由端口流体耦合，以及设置在流体隔室和储存器之间的限制膜区域。

7. 发明授权

US5779734A Covering for an implantable prosthetic device 失效
标题翻译：覆盖植入式假体装置
公开(公告)号：US5779734A
公开(公告)日：1998-07-14
申请号：US821225
申请日：1997-03-20
申请人： Walter J. Ledergerber
发明人： Walter J. Ledergerber
IPC分类号： A61F2/00 , A61F2/12 , A61L27/34 , A61F2/02
CPC分类号： A61F2/12 , A61F2/0077 , A61L27/34
摘要： An implant and coverings for an implant for use in the human body are disclosed. Coverings for implants are constructed to present a biocompatible surface to the body and to provide a textured surface which serves to disorganize scar tissue which forms around the implant. Filaments of expanded PTFEe are attached to a stretch fabric backing in a loose weave configuration. Silicone molded in geometric patterns may be employed to present a textured surface. Compressive structures may be beneficially used on the surface of the implant or in the interior of the implant. Foam is one such compressive structure. Hexagonally shaped compressive cells containing fluid, gas, gel or foam are adapted to receive an insert which contains an outer biocompatible coating. A valve or port is provided to communicate between the cell and the body. Expansion means may be provided to expand the implant in a desired direction.
摘要翻译：公开了一种用于人体植入物的植入物和覆盖物。用于植入物的覆盖物构造成向身体提供生物相容性表面并提供纹理化表面，其用于混合在植入物周围形成的瘢痕组织。膨胀PTFEe的长丝以松散的织造结构附着在拉伸织物背衬上。可以使用以几何图案模制的硅树脂呈现纹理表面。压缩结构可有利地用于植入物的表面或植入物的内部。泡沫是一种这样的压缩结构。包含流体，气体，凝胶或泡沫的六边形压缩细胞适于接收包含外部生物相容性涂层的插入物。提供阀或端口以在电池和主体之间连通。可以提供扩展装置以沿期望的方向扩展植入物。

8. 发明授权

US5354338A Texturized covering for implants 失效
标题翻译：植入物的纹理覆盖物
公开(公告)号：US5354338A
公开(公告)日：1994-10-11
申请号：US660291
申请日：1991-02-22
申请人： Walter J. Ledergerber
发明人： Walter J. Ledergerber
IPC分类号： A61F2/00 , A61F2/12
CPC分类号： A61F2/12 , A61F2/0077
摘要： Methods for manufacturing texturized coverings for implants into the human body are described which generate small wells or channels on the exterior surface of the implant. Optionally, the texturized surface may be formed by affixing globules on the exterior surface of a mandrel or the interior surface of a mold, which is then coated with silicone rubber and cured. The surface may be optionally microtexturized, for example, by microtexturizing the surface of the globules by etching or sand blasting.
摘要翻译：描述了用于制造植入人体的纹理化覆盖物的方法，其在植入物的外表面上产生小孔或通道。任选地，可以通过将球体固定在心轴的外表面或模具的内表面上，然后用硅橡胶涂覆并固化来形成纹理化表面。表面可以任选地进行微绒毛化，例如通过蚀刻或喷砂将微球的表面微孔化。

9. 发明授权

US06921418B2 Dual-sided, texturized biocompatible structure 失效
标题翻译：双面，纹理化的生物相容结构
公开(公告)号：US06921418B2
公开(公告)日：2005-07-26
申请号：US09813091
申请日：2001-03-19
申请人： Walter J. Ledergerber
发明人： Walter J. Ledergerber
IPC分类号： A61B19/00 , A61F2/00 , A61F2/12 , A61L27/34 , A61F2/02 , A61B17/08
CPC分类号： A61L27/34 , A61B90/02 , A61F2/0077 , A61F2/12 , C08L27/18 , C08L75/04 , C08L83/04
摘要： A soft tissue expander has enhanced performance through use of differential and directional expandability, continuous expansion capability, increased base and dimensional stability, increased soft tissue purchase by virtue of unique surface topography, and results in improved cavity contour after expansion. Expansion means may be provided to expand the implant in a desired direction. In the preferred embodiment, an expander or implant has an exterior surface defining a volume, the exterior surface including a base portion, a first wall and a second wall, wherein the second wall is relatively thinner than the first wall. A fill port, which may be integrally molded into the expander, is included. As the expander is inflated, differential expansion occurs with the relatively thin second wall section expanding more than that of the first wall section. The base may include ribs or other molded-in structures to increase structural integrity. Optionally, a bellows may be included on the exterior surface of the expander, the bellows optionally including a limiting ring. Molded-in geometric patterns may be employed to present textured internal, as well as external surfaces to the implant or expander. Compressive structures may be used on the inside or outside surface of the implant.
摘要翻译：软组织扩张器通过使用差异性和定向可扩展性，连续扩张能力，增加的基础和尺寸稳定性，通过独特的表面形貌增加软组织购买而增强了性能，并且在扩张后导致改进的腔轮廓。可以提供扩展装置以沿期望的方向扩展植入物。在优选实施例中，膨胀器或植入物具有限定体积的外表面，外表面包括基部，第一壁和第二壁，其中第二壁相对于第一壁相对较薄。包括可以整体模制在膨胀机中的填充口。当膨胀器膨胀时，发生差异膨胀，相对较薄的第二壁部比第一壁部的膨胀更大。底座可以包括肋或其它模制结构以增加结构完整性。可选地，波纹管可以包括在膨胀机的外表面上，波纹管可选地包括限位环。可以使用成型的几何图案来呈现纹理化的内部以及外部表面到植入物或扩张器。压缩结构可用于植入物的内表面或外表面。

10. 发明授权

US5723006A Breast implant introducer 失效
标题翻译：乳房植入物导引器
公开(公告)号：US5723006A
公开(公告)日：1998-03-03
申请号：US646845
申请日：1996-05-08
申请人： Walter J. Ledergerber
发明人： Walter J. Ledergerber
IPC分类号： A61F2/12 , A61B17/02
CPC分类号： A61F2/12
摘要： A tool and method for introducing an implant through an incision in a body utilizing a tube having a hole through which the implant is pressed. In the preferred embodiment, a two part tube has one opened end and one closed end. The tube contains an expanding structure, for applying pressure on the implant, optionally a pressure transmitting structure, and an implant. The expanding structure is expanded optionally by gas or fluid filling the structure. Optionally, a collar is disposed around the tube near the opening, selectively covering and uncovering a cut-out in the tube which permits manipulation of the implant prior to insertion.
摘要翻译：一种用于通过切口在体内引入植入物的工具和方法，其利用具有孔的管，所述孔具有通过其施加植入物的孔。在优选实施例中，两部分管具有一个开口端和一个封闭端。该管包含用于在植入物上施加压力，任选的压力传递结构和植入物的扩展结构。膨胀结构可任选地通过填充结构的气体或流体膨胀。可选地，套管围绕开口处设置在管周围，选择性地覆盖和露出管中的切口，其允许在插入之前对植入物进行操纵。

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