专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06568390B2 Dual capillary fluid vaporizing device 有权
标题翻译：双毛细管流体蒸发装置
公开(公告)号：US06568390B2
公开(公告)日：2003-05-27
申请号：US09956966
申请日：2001-09-21
申请人： Walter A. Nichols , Kenneth A. Cox , Tung Tien Nguyen
发明人： Walter A. Nichols , Kenneth A. Cox , Tung Tien Nguyen
IPC分类号： A61M1500
CPC分类号： A61M15/00 , A61M11/007 , A61M11/042 , A61M15/025 , A61M2016/0024
摘要： A fluid vaporizing device useful for vaporizing fluid into an aerosol and includes first and second capillary tubes connected electrically in series by providing separate electrodes at the inlet ends of each capillary tube, and connecting the outlet ends of the capillary tubes by an electrical connection that connects the outlet ends both electrically and thermally. The capillary tubes are heated by the flow of electricity therethrough, and liquid flowing through the tubes is vaporized. The outlet ends of the capillary tubes are easily maintained at a temperature for optimizing aerosol generation since there is minimal heat loss through the connection connecting the outlet ends.
摘要翻译：一种流体蒸发装置，其用于将流体蒸发成气溶胶，并且包括通过在每个毛细管的入口端处提供分开的电极串联电连接的第一和第二毛细管，并且通过电连接连接毛细管的出口端，该电连接出口端部电气和热端都结束。毛细管由电流通过其加热，流过管的液体被蒸发。毛细管的出口端容易地保持在用于优化气溶胶产生的温度，因为通过连接出口端的连接件具有最小的热损失。

2. 发明授权

US06715487B2 Dual capillary fluid vaporizing device 有权
标题翻译：双毛细管流体蒸发装置
公开(公告)号：US06715487B2
公开(公告)日：2004-04-06
申请号：US10430272
申请日：2003-05-07
申请人： Walter A. Nichols , Kenneth A. Cox , Tung Tien Nguyen
发明人： Walter A. Nichols , Kenneth A. Cox , Tung Tien Nguyen
IPC分类号： A61M1500
CPC分类号： A61M15/00 , A61M11/007 , A61M11/042 , A61M15/025 , A61M2016/0024
摘要： A fluid vaporizing device useful for vaporizing fluid into an aerosol and includes first and second capillary tubes connected electrically in series by providing separate electrodes at the inlet ends of each capillary tube, and connecting the outlet ends of the capillary tubes by an electrical connection that connects the outlet ends both electrically and thermally. The capillary tubes are heated by the flow of electricity therethrough, and liquid flowing through the tubes is vaporized. The outlet ends of the capillary tubes are easily maintained at a temperature for optimizing aerosol generation since there is minimal heat loss through the connection connecting the outlet ends.
摘要翻译：一种流体蒸发装置，其用于将流体蒸发成气溶胶，并且包括通过在每个毛细管的入口端处提供分开的电极串联电连接的第一和第二毛细管，并且通过电连接连接毛细管的出口端，该电连接出口端部电气和热端都结束。毛细管由电流通过其加热，流过管的液体被蒸发。毛细管的出口端容易地保持在用于优化气溶胶产生的温度，因为通过连接出口端的连接件具有最小的热损失。

3. 发明授权

US06640050B2 Fluid vaporizing device having controlled temperature profile heater/capillary tube 有权
公开(公告)号：US06640050B2
公开(公告)日：2003-10-28
申请号：US09957026
申请日：2001-09-21
申请人： Walter A. Nichols , Kenneth A. Cox , Douglas D. McRae , Tung Tien Nguyen
发明人： Walter A. Nichols , Kenneth A. Cox , Douglas D. McRae , Tung Tien Nguyen
IPC分类号： F24F600
CPC分类号： A61M11/041 , A61M11/001 , A61M11/007 , A61M11/042 , A61M15/025 , A61M2016/0021 , A61M2205/8206
摘要： A fluid vaporizing device useful for vaporizing fluid into an aerosol includes a capillary tube made from an electrically conductive material, an upstream electrode connected to the tube, and a downstream electrode connected to the tube and provided with an electrical resistivity sufficient to cause heating of the downstream electrode during operation to approximately the same temperature as the tube at the point of connection. The upstream and downstream electrodes connected to the capillary tube divide the tube into an initial feed section, a heated section, and a tip. A source of material to be volatilized is provided to the tube at the feed section, passes downstream into the heated section, is vaporized, and then exits from the tube through the tip. The temperature profile of the tube along the heated section is controlled by varying parameters to substantially eliminate any effect of the downstream electrode as a heat sink. These parameters may include the electrical resistivity of the downstream electrode, its cross-sectional area, and its length.

4. 发明授权

US07117867B2 Aerosol generator and methods of making and using an aerosol generator 有权
公开(公告)号：US07117867B2
公开(公告)日：2006-10-10
申请号：US10438329
申请日：2003-05-15
申请人： Kenneth A. Cox , Timothy Paul Beane , William R. Sweeney , Walter A. Nichols , F. Murphy Sprinkel, Jr.
发明人： Kenneth A. Cox , Timothy Paul Beane , William R. Sweeney , Walter A. Nichols , F. Murphy Sprinkel, Jr.
IPC分类号： A61M11/00 , A61M15/00 , A61M16/00 , F16K11/00
CPC分类号： A61M15/008 , A24F47/008 , A61M11/007 , A61M11/042 , A61M15/0003 , A61M15/0066 , A61M15/0083 , A61M2016/0039 , A61M2205/10 , A61M2205/3561 , A61M2205/3653 , A61M2205/50 , A61M2205/52 , A61M2205/8225
摘要： An aerosol generator includes a flow passage having an inlet and an outlet, a heater arranged relative to the flow passage for heating the flow passage, a source of material to be volatilized in communication with the inlet of the flow passage, a valve to open and close communication between the source of material and the inlet of the flow passage, and a pressurization arrangement for causing material in the source of material to be introduced into the flow passage when the valve is in an open position. The aerosol generator further includes a source of power for operating the heater and the valve, and a control device for controlling supply of power from the source of power to the heater and the valve. A metering device in an inhaler includes a pressurized source of medicated fluid and a metering chamber configured to deliver a predetermined volume of fluid to a heated flow passage in the inhaler. The metering chamber can be part of a rotary valve having a bore and a displacement member moveable within the bore from a first position where the fluid is loaded into the bore to a second position where the predetermined volume is ejected out of the bore. Another metering chamber has an elastic portion of a delivery passage in fluid communication with the pressurized source of liquid and the elastic portion of the delivery passage is deformed to eject the predetermined volume.

5. 发明授权

US06516796B1 Aerosol generator and methods of making and using an aerosol generator 有权
标题翻译：气溶胶发生器和制造和使用气溶胶发生器的方法
公开(公告)号：US06516796B1
公开(公告)日：2003-02-11
申请号：US09479597
申请日：2000-01-07
申请人： Kenneth A. Cox , Timothy Paul Beane , William R. Sweeney , Walter A. Nichols , F. Murphy Sprinkel, Jr.
发明人： Kenneth A. Cox , Timothy Paul Beane , William R. Sweeney , Walter A. Nichols , F. Murphy Sprinkel, Jr.
IPC分类号： A61M1100
CPC分类号： A61M15/008 , A24F47/008 , A61M11/007 , A61M11/042 , A61M15/0003 , A61M15/0066 , A61M15/0083 , A61M2016/0039 , A61M2205/10 , A61M2205/3561 , A61M2205/3653 , A61M2205/50 , A61M2205/52 , A61M2205/8225
摘要： An aerosol generator includes a flow passage having an inlet and an outlet, a heater arranged relative to the flow passage for heating the flow passage, a source of material to be volatilized in communication with the inlet of the flow passage, a valve to open and close communication between the source of material and the inlet of the flow passage, and a pressurization arrangement for causing material in the source of material to be introduced into the flow passage when the valve is in an open position. The aerosol generator further includes a source of power for operating the heater and the valve, and a control device for controlling supply of power from the source of power to the heater and the valve. A metering device in an inhaler includes a pressurized source of medicated fluid and a metering chamber configured to deliver a predetermined volume of fluid to a heated flow passage in the inhaler. The metering chamber can be part of a rotary valve having a bore and a displacement member moveable within the bore from a first position where the fluid is loaded into the bore to a second position where the predetermined volume is ejected out of the bore. Another metering chamber has an elastic portion of a delivery passage in fluid communication with the pressurized source of liquid and the elastic portion of the delivery passage is deformed to eject the predetermined volume.
摘要翻译：气雾发生器包括具有入口和出口的流动通道，相对于流道设置的加热流道的加热器，与流动通道的入口连通的待挥发的材料源，打开的阀和材料源与流路入口之间的紧密连通，以及用于当阀处于打开位置时将材料源中的材料引入流路的加压装置。气溶胶发生器还包括用于操作加热器和阀的动力源，以及用于控制从动力源到加热器和阀的动力供应的控制装置。吸入器中的计量装置包括加压的药液源和配置成将预定体积的流体输送到吸入器中的加热流动通道的计量腔。计量室可以是具有孔的旋转阀的一部分，以及位于孔内的位移元件，该位移元件从第一位置移动到第二位置，在第一位置，流体被加载到孔中到第二位置，其中预定的体积被排出孔。另一个计量室具有与加压液体流体连通的输送通道的弹性部分，并且输送通道的弹性部分变形以排出预定体积。

6. 发明授权

US07500479B2 Aerosol generators and methods for producing aerosols 有权
标题翻译：气溶胶发生器和生产气溶胶的方法
公开(公告)号：US07500479B2
公开(公告)日：2009-03-10
申请号：US11113298
申请日：2005-04-25
申请人： Walter A. Nichols , Rajiv Gupta , Gene G. Faison , Kenneth A. Cox
发明人： Walter A. Nichols , Rajiv Gupta , Gene G. Faison , Kenneth A. Cox
IPC分类号： A61M11/00
CPC分类号： A61M15/00 , A61M11/007 , A61M11/042 , A61M15/025 , A61M2016/0021 , B05B7/1686 , B05B9/002 , B05B9/08 , B05B17/04
摘要： An aerosol generator includes a flow passage having an inlet end, an outlet end, and a constriction in the flow passage at the outlet end. A heater is operable to heat liquid in the flow passage to produce a vapor, which is expelled from the outlet end of the flow passage.
摘要翻译：气溶胶发生器包括具有入口端，出口端和在出口端的流动通道中的收缩部的流动通道。加热器可操作以加热流动通道中的液体，以产生从流动通道的出口端排出的蒸气。

7. 发明申请

US20080268060A1 Methods and apparatus for producing nanoscale particles 有权
标题翻译：制备纳米级颗粒的方法和装置
公开(公告)号：US20080268060A1
公开(公告)日：2008-10-30
申请号：US12149604
申请日：2008-05-05
申请人： Tung T. Nguyen , Nina Brown , Jui C. Lin , Stephen Pham , Kenneth A. Cox , Douglas D. McRae , Walter A. Nichols
发明人： Tung T. Nguyen , Nina Brown , Jui C. Lin , Stephen Pham , Kenneth A. Cox , Douglas D. McRae , Walter A. Nichols
IPC分类号： A61K9/14 , A61K31/58 , A61K31/137
CPC分类号： A61K31/137 , A61K9/0073 , A61K31/573 , A61K47/08 , A61K47/10 , A61M11/041 , A61M11/042 , A61M15/0025 , A61M15/025 , A61M2016/0021 , A61M2205/8206 , A61M2205/8237
摘要： Liquid nanoscale particle precursor materials for generating nanoscale particles include at least one high volatility carrier and a second component. A nanoscale particle generating device generates nanoscale particles by passing a liquid nanoscale particle precursor material through a flow passage heated to convert the carrier into a vapor and the second component into nanoscale particles. The nanoscale particles preferably consist essentially of the second component and can consist essentially of dry, solid particles. The particle generator can be incorporated in a hand held inhaler, and can be delivered to a targeted portion of the lung using the inhaler. Composite controlled release particles of micron or nanoscale size can be produced by flowing a solution of medicament, control release agent and carrier liquid through a capillary heater.
摘要翻译：用于产生纳米尺寸颗粒的液体纳米级颗粒前体材料包括至少一种高挥发性载体和第二组分。纳米级粒子产生装置通过使液体纳米级粒子前体材料通过加热的流动通道将载体转化为蒸气并将第二组分转变为纳米级颗粒而产生纳米级颗粒。纳米尺度颗粒优选基本上由第二组分组成，并且可以基本上由干燥的固体颗粒组成。颗粒发生器可以并入手持式吸入器中，并且可以使用吸入器输送到肺的目标部分。可以通过使药物，控制释放剂和载液的溶液流过毛细管加热器来生产微米或纳米尺寸的复合控制释放颗粒。

8. 发明授权

US07147170B2 Aerosol generating device and method of use thereof 有权
标题翻译：气雾发生装置及其使用方法
公开(公告)号：US07147170B2
公开(公告)日：2006-12-12
申请号：US10655017
申请日：2003-09-05
申请人： Tung T. Nguyen , Douglas D. McRae , Kenneth A. Cox , Walter A. Nichols , Ulysses Smith , Gary E. Grollimund , Donald L. Brookman
发明人： Tung T. Nguyen , Douglas D. McRae , Kenneth A. Cox , Walter A. Nichols , Ulysses Smith , Gary E. Grollimund , Donald L. Brookman
IPC分类号： B05B1/24 , A61M11/00
CPC分类号： B05B17/04 , A61M11/001 , A61M11/041 , A61M11/042 , A61M15/008 , A61M15/025 , A61M2205/50 , A61M2205/8206 , B05B1/24
摘要： An aerosol generating device generates an aerosol having a desired particle size by passing a liquid through a flow passage heated to convert the liquid into a vapor. The flow passage includes an outlet section that controls the exit velocity of the vapor and produces an aerosol with a desired particle size. The aerosol generator can be incorporated in a hand held inhaler, and the liquid can include a medicament, which is delivered to a targeted portion of the lung using the inhaler.
摘要翻译：气溶胶发生装置通过使液体通过加热的流体将液体转化为蒸气而产生具有所需粒径的气溶胶。流动通道包括一个出口部分，其控制蒸气的出口速度并产生具有所需粒径的气溶胶。气溶胶发生器可以结合在手持式吸入器中，并且液体可以包括药物，其使用吸入器输送到肺的目标部分。

9. 发明授权

US06923179B2 Aerosol generating devices and methods for generating aerosols having controlled particle sizes 有权
公开(公告)号：US06923179B2
公开(公告)日：2005-08-02
申请号：US10654980
申请日：2003-09-05
申请人： Rajiv Gupta , Douglas D. McRae , Kenneth A. Cox , Walter A. Nichols
发明人： Rajiv Gupta , Douglas D. McRae , Kenneth A. Cox , Walter A. Nichols
IPC分类号： A61M11/00 , A61M11/04 , A61M15/00 , B05B1/24 , B05B7/00 , A61M16/00 , H05B3/00
CPC分类号： B05B1/24 , A61M11/002 , A61M11/041 , A61M11/042 , A61M15/00 , A61M2205/50 , B05B7/0012
摘要： An aerosol generating device includes a housing, a heater and an optional mouthpiece. The heater volatilizes liquid within a flow passage and forms an aerosol in the mouthpiece. An aerosol confinement sleeve is disposed to control the size distribution of the aerosol.

10. 发明授权

US06701921B2 Aerosol generator having heater in multilayered composite and method of use thereof 有权
公开(公告)号：US06701921B2
公开(公告)日：2004-03-09
申请号：US09742320
申请日：2000-12-22
申请人： F. Murphy Sprinkel, Jr. , Walter A. Nichols , Kenneth A. Cox , Timothy S. Sherwood , Scott A. Sowers , Zelita R. Washington , Sirisha Reddy
发明人： F. Murphy Sprinkel, Jr. , Walter A. Nichols , Kenneth A. Cox , Timothy S. Sherwood , Scott A. Sowers , Zelita R. Washington , Sirisha Reddy
IPC分类号： A61M1600
CPC分类号： A61M15/0065 , A61M11/041 , A61M11/044 , A61M2016/0021 , A61M2205/123 , A61M2205/128 , A61M2205/3653 , A61M2205/8206
摘要： An aerosol generator includes a fluid passage arranged between a first and a second layer wherein the first and second layers at least partially define the fluid passage. A liquid supply is arranged to provide a fluid in liquid phase to the fluid passage. The aerosol generator also includes a heater arranged to volatilize the fluid in the fluid passage. An outlet of the aerosol generator is arranged to receive the volatilized fluid and direct the volatilized fluid out of the fluid passage. The aerosol generator can be used to generate aerosols containing medicated materials.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式