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1. 发明申请

US20120022316A1 Method and Apparatus for Preventing Air Embolisms 审中-公开
标题翻译：防止空气栓塞的方法和装置
公开(公告)号：US20120022316A1
公开(公告)日：2012-01-26
申请号：US13252062
申请日：2011-10-03
申请人： Walid N. Aboul-Hosn , William R. Kanz , Jonathon Spangler
发明人： Walid N. Aboul-Hosn , William R. Kanz , Jonathon Spangler
IPC分类号： A61M1/10 , A61M25/00
CPC分类号： A61M1/367 , A61B2017/00243 , A61B2017/3419 , A61B2017/3492 , A61M1/36 , A61M1/3653 , A61M1/3659 , A61M1/3666
摘要： Method and apparatus for preventing air embolisms during surgical procedures which involves providing a fluid source in communication with an aperture extending into an anatomical cavity such that fluid may be delivered into the cavity when a condition of negative pressure exists in the cavity, thereby preventing the introduction of air into the cavity.
摘要翻译：用于在手术过程中防止空气栓塞的方法和装置，其包括提供与延伸到解剖腔中的孔连通的流体源，使得当空腔中存在负压的状况时，流体可被输送到腔中，从而防止引入的空气进入腔。

2. 发明授权

US06935344B1 Methods and systems for providing right and/or left heart support during cardiac surgery 失效
标题翻译：在心脏手术期间提供右心和/或左心支持的方法和系统
公开(公告)号：US06935344B1
公开(公告)日：2005-08-30
申请号：US09481730
申请日：2000-01-11
申请人： Walid N. Aboul-Hosn , William R. Kanz
发明人： Walid N. Aboul-Hosn , William R. Kanz
IPC分类号： A61M25/00 , A61B18/18 , A61B19/00 , A61M1/10 , A61M1/36 , A61M3/00 , A61M5/00 , A61M25/16
CPC分类号： A61M1/3653 , A61M1/1008 , A61M1/101 , A61M1/1012 , A61M1/1029 , A61M1/1086 , A61M1/122 , A61M1/125 , A61M1/3659 , A61M2205/32 , A61M2205/3334 , Y10S415/90
摘要： The present invention relates to systems and methods for performing beating heart surgery involving the step of maintaining at least partial blood flow through a protected blood flow path within the right and/or left side of the heart during surgery. The protected blood flow path may be established by positioning one or more conduits within at least a portion of the right and/or left sides(s) of the heart. In a first system, at least partial blood flow may be maintained through the protected blood flow path by the pumping action of a blood pump communicatively coupled to the conduit. In a second system, at least partial blood flow is maintained through the protected blood flow path by the pumping action of the beating heart itself. The systems are therefore capable of maintaining at least partial blood flow through the right and/or left side(s) of the heart, even during periods when the cardiac output becomes compromised. The patient's lung(s) may be used at all times utilized for blood oxygenation during heart surgery, thereby avoiding the need for artificial cardiopulmonary bypass (CPB) circuits and the attendant disadvantages of CPB.
摘要翻译：本发明涉及用于执行心跳手术的系统和方法，该系统和方法涉及在手术期间保持至少部分血流通过心脏右侧和/或左侧的受保护血流路径的步骤。受保护的血流路径可以通过将心脏的右侧和/或左侧的至少一部分中的一个或多个管道定位来建立。在第一系统中，可以通过通气地联接到导管的血液泵的作用，通过受保护的血流路径来保持至少部分血液流动。在第二系统中，通过跳动心脏本身的泵送作用，通过受保护的血液流路保持至少部分血流。因此，即使在心输出量损失的时期，这些系统也能够保持至少部分血液流过心脏的右侧和/或左侧。患者的肺部可以随时用于心脏手术期间的血氧饱和度，从而避免了对人造心肺旁路（CPB）电路的需要以及CPB伴随的缺点。

3. 发明授权

US06295877B1 Pressure sensing cannula 失效
标题翻译：压力传感套管
公开(公告)号：US06295877B1
公开(公告)日：2001-10-02
申请号：US09280970
申请日：1999-03-30
申请人： Walid N. Aboul-Hosn , William R. Kanz , Kelly J. McCrystle , Desmond P. O'Connell
发明人： Walid N. Aboul-Hosn , William R. Kanz , Kelly J. McCrystle , Desmond P. O'Connell
IPC分类号： G01L700
CPC分类号： A61B90/06 , A61B2090/064 , A61B2090/306 , A61M2025/0002
摘要： A cannula is provided with one or more pressure transducers for measuring fluid pressure interiorly or exteriorly of the cannula. The pressure transducers may be mounted integrally with the tubular wall defining the main lumen of the cannula, or they may comprise differential pressure transducers mounted in dedicated lumens in communication with the main lumen. The pressure measurements from the transducers is used to determine fluid flow rate.
摘要翻译：插管设置有一个或多个压力换能器，用于测量套管内部或外部的流体压力。压力传感器可以与限定插管的主腔的管状壁一体地安装，或者它们可以包括安装在与主腔连通的专用腔内的差压换能器。使用来自换能器的压力测量来确定流体流速。

4. 发明授权

US06974436B1 Integrated pump and cannula system and related methods 失效
标题翻译：综合泵和套管系统及相关方法
公开(公告)号：US06974436B1
公开(公告)日：2005-12-13
申请号：US09889442
申请日：2000-01-14
申请人： Walid N. Aboul-Hosn , William R. Kanz , James W. Cartwright , Damien Shulock , Kelly J. McCrystle
发明人： Walid N. Aboul-Hosn , William R. Kanz , James W. Cartwright , Damien Shulock , Kelly J. McCrystle
IPC分类号： A61M25/00 , A61B18/18 , A61B19/00 , A61M1/10 , A61M1/36 , A61M3/00 , A61M5/00 , A61M25/16
CPC分类号： A61M1/3653 , A61M1/1008 , A61M1/101 , A61M1/1012 , A61M1/1029 , A61M1/1086 , A61M1/122 , A61M1/125 , A61M1/3659 , A61M2205/32 , A61M2205/3334 , Y10S415/90
摘要： The present invention relates to systems and methods for transporting fluid between different locations within a body cavity and, in one particular application, systems and methods for transporting fluids to maintain at least partial blood flow through a protected blood flow path within the right and/or left side of the heart during surgery. The protected blood flow path may be established by positioning one or more conduits within at least a portion of the right and/or left sides(s) of the heart. At least partial blood flow may be maintained through the protected blood flow path by the pumping action of a blood pump disposed within the conduit.
摘要翻译：本发明涉及用于在体腔内的不同位置之间输送流体的系统和方法，并且在一个特定应用中，用于输送流体以保持至少部分血液流过右侧和/或右侧的受保护血液流动路径的系统和方法手术左侧心脏。受保护的血流路径可以通过将心脏的右侧和/或左侧的至少一部分中的一个或多个管道定位来建立。通过设置在导管内的血液泵的作用，至少可以通过受保护的血液流路维持血液流动。

5. 发明授权

US08888728B2 Guidable intravascular blood pump and related methods 有权
标题翻译：可引导血管内血液泵及相关方法
公开(公告)号：US08888728B2
公开(公告)日：2014-11-18
申请号：US12772810
申请日：2010-05-03
申请人： Walid N. Aboul-Hosn , William R. Kanz , Bruce A. Baker
发明人： Walid N. Aboul-Hosn , William R. Kanz , Bruce A. Baker
IPC分类号： A61M1/12 , A61M1/10
CPC分类号： A61M1/125 , A61M1/1008 , A61M1/101 , A61M1/1012 , A61M1/1013 , A61M1/102 , A61M1/1029 , A61M1/1031 , A61M1/1034 , A61M1/1086 , A61M1/1096 , A61M1/122 , A61M25/09 , A61M2025/0177 , A61M2025/0183 , A61M2205/3348 , Y10S415/90
摘要： An improved intravascular blood pump and related methods involving the broad inventive concept of equipping the intravascular blood pump with guiding features such that the intravascular blood pump can be selectively positioned at a predetermined location within the circulatory system of a patient.
摘要翻译：改进的血管内血液泵和相关方法涉及将血管内血液泵装备为具有引导特征的广泛的发明构思，使得血管内血液泵可以选择性地定位在患者的循环系统内的预定位置。

6. 发明授权

US07785246B2 Left and right side heart support 有权
标题翻译：左右右心支持
公开(公告)号：US07785246B2
公开(公告)日：2010-08-31
申请号：US11018872
申请日：2004-12-21
申请人： Walid N. Aboul-Hosn , William R. Kanz , Jodi Akin , Michael Guidera , Robert G. Matheny
发明人： Walid N. Aboul-Hosn , William R. Kanz , Jodi Akin , Michael Guidera , Robert G. Matheny
IPC分类号： A61M25/00
CPC分类号： A61M1/3621 , A61M1/1008 , A61M1/101 , A61M1/1096 , A61M1/12 , A61M1/122 , A61M1/3663
摘要： A cannulation system for cardiac support uses an inner cannula disposed within an outer cannula. The outer cannula includes a fluid inlet for placement within the right atrium of a heart. The inner cannula includes a fluid inlet extending through the fluid inlet of the outer cannula and the atrial septum for placement within at least one of the left atrium and left ventricle of the heart. The cannulation system also employs a pumping assembly coupled to the inner and outer cannulas to withdraw blood from the right atrium for delivery to the pulmonary artery to provide right heart support, or to withdraw blood from at least one of the left atrium and left ventricle for delivery into the aorta to provide left heart support, or both.
摘要翻译：用于心脏支架的插管系统使用设置在外套管内的内套管。外套管包括用于放置在心脏右心房内的流体入口。内套管包括延伸穿过外套管和心房隔膜的流体入口的流体入口，用于放置在心脏的左心房和左心室中的至少一个中。插管系统还采用耦合到内插管和外插管的抽吸组件，以从右心房抽取血液以递送到肺动脉以提供正确的心脏支持，或者从左心房和左心室中的至少一个抽出血液输送到主动脉以提供左心脏支持，或两者兼而有之。

7. 发明申请

US20100210895A1 Guidable Intravascular Blood Pump and Related Methods 有权
标题翻译：可导引血管内血泵及相关方法
公开(公告)号：US20100210895A1
公开(公告)日：2010-08-19
申请号：US12772810
申请日：2010-05-03
申请人： Walid N. Aboul-Hosn , William R. Kanz , Bruce A. Baker
发明人： Walid N. Aboul-Hosn , William R. Kanz , Bruce A. Baker
IPC分类号： A61M1/12
CPC分类号： A61M1/125 , A61M1/1008 , A61M1/101 , A61M1/1012 , A61M1/1013 , A61M1/102 , A61M1/1029 , A61M1/1031 , A61M1/1034 , A61M1/1086 , A61M1/1096 , A61M1/122 , A61M25/09 , A61M2025/0177 , A61M2025/0183 , A61M2205/3348 , Y10S415/90
摘要： An improved intravascular blood pump and related methods involving the broad inventive concept of equipping the intravascular blood pump with guiding features such that the intravascular blood pump can be selectively positioned at a predetermined location within the circulatory system of a patient.
摘要翻译：改进的血管内血液泵和相关方法涉及将血管内血液泵装备为具有引导特征的广泛的发明构思，使得血管内血液泵可以选择性地定位在患者的循环系统内的预定位置。

8. 发明申请

US20110021865A1 Left and Right Side Heart Support 有权
标题翻译：左右侧心脏支持
公开(公告)号：US20110021865A1
公开(公告)日：2011-01-27
申请号：US12846366
申请日：2010-07-29
申请人： Walid N. Aboul-Hosn , William R. Kanz , Jodi Akin , Michael Guidera , Robert G. Matheny
发明人： Walid N. Aboul-Hosn , William R. Kanz , Jodi Akin , Michael Guidera , Robert G. Matheny
IPC分类号： A61M1/10
CPC分类号： A61M1/3621 , A61M1/1008 , A61M1/101 , A61M1/1096 , A61M1/12 , A61M1/122 , A61M1/3663
摘要： A cannulation system for cardiac support uses an inner cannula disposed within an outer cannula. The outer cannula includes a fluid inlet for placement within the right atrium of a heart. The inner cannula includes a fluid inlet extending through the fluid inlet of the outer cannula and the atrial septum for placement within at least one of the left atrium and left ventricle of the heart. The cannulation system also employs a pumping assembly coupled to the inner and outer cannulas to withdraw blood from the right atrium for delivery to the pulmonary artery to provide right heart support, or to withdraw blood from at least one of the left atrium and left ventricle for delivery into the aorta to provide left heart support, or both.
摘要翻译：用于心脏支架的插管系统使用设置在外套管内的内套管。外套管包括用于放置在心脏右心房内的流体入口。内套管包括延伸穿过外套管和心房隔膜的流体入口的流体入口，用于放置在心脏的左心房和左心室中的至少一个中。插管系统还采用耦合到内插管和外插管的抽吸组件，以从右心房抽取血液以递送到肺动脉以提供正确的心脏支持，或者从左心房和左心室中的至少一个抽出血液输送到主动脉以提供左心脏支持，或两者兼而有之。

9. 发明授权

US06926662B1 Left and right side heart support 有权
标题翻译：左右右心支持
公开(公告)号：US06926662B1
公开(公告)日：2005-08-09
申请号：US09868973
申请日：1999-12-23
申请人： Walid N. Aboul-Hosn , William R. Kanz , Jodi Akin , Michael Guidera , Robert G. Matheny
发明人： Walid N. Aboul-Hosn , William R. Kanz , Jodi Akin , Michael Guidera , Robert G. Matheny
IPC分类号： A61M1/10 , A61M1/36
CPC分类号： A61M1/3621 , A61M1/1008 , A61M1/101 , A61M1/1096 , A61M1/12 , A61M1/122 , A61M1/3663
摘要： A cannulation system for cardiac support uses an inner cannula disposed within an outer cannula. The outer cannula includes a fluid inlet for placement within the right atrium of a heart. The inner cannula includes a fluid inlet extending through the fluid inlet of the outer cannula and the atrial septum for placement within at least one of the left atrium and left ventricle of the heart. The cannulation system also employs a pumping assembly coupled to the inner and outer cannulas to withdraw blood from the right atrium for delivery to the pulmonary artery to provide right heart support, or to withdraw blood from at least one of the left atrium and left ventricle for delivery into the aorta to provide left heart support, or both.
摘要翻译：用于心脏支架的插管系统使用设置在外套管内的内套管。外套管包括用于放置在心脏右心房内的流体入口。内套管包括延伸穿过外套管和心房隔膜的流体入口的流体入口，用于放置在心脏的左心房和左心室中的至少一个中。插管系统还采用耦合到内插管和外插管的抽吸组件，以从右心房抽取血液以递送到肺动脉以提供正确的心脏支持，或者从左心房和左心室中的至少一个抽出血液输送到主动脉以提供左心脏支持，或两者兼而有之。

10. 发明授权

US06287319B1 Cannula with balloon tip 失效
标题翻译：插管与气球提示
公开(公告)号：US06287319B1
公开(公告)日：2001-09-11
申请号：US09280987
申请日：1999-03-30
申请人： Walid N. Aboul-Hosn , William R. Kanz , Eloy T. Padilla , Terry M. Wonder
发明人： Walid N. Aboul-Hosn , William R. Kanz , Eloy T. Padilla , Terry M. Wonder
IPC分类号： A61M2900
CPC分类号： A61M25/0125 , A61M25/10
摘要： A cannula is provided with a balloon tip at an implantable end thereof. The balloon tip comprises a sealed, flexible, inflatable portion adapted to receive an inflating material via a lumen in fluid communication therewith. The lumen comprises a gap formed in the tubular wall of the cannula, and may be defined by a supply tube disposed within the lumen and extending between an inflatable material source and the balloon tip.
摘要翻译：插管在其可植入端设置有气囊尖端。气囊尖端包括密封的，柔性的可充气部分，其适于通过与其流体连通的内腔接收充气材料。管腔包括形成在套管的管状壁中的间隙，并且可以由设置在内腔内并在可膨胀材料源和球囊末端之间延伸的供应管限定。

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