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1. 发明申请

WO2006082509A2 A SOLID PHENOLIC CORE AND PREPARATION METHOD THEREOF 审中-公开
标题翻译：一种固体酚醛树脂及其制备方法
公开(公告)号：WO2006082509A2
公开(公告)日：2006-08-10
申请号：PCT/IB2006/000211
申请日：2006-02-03
申请人： WILSONART (SHANGHAI) CO., LTD. , GUO, Chaohui , ZHONG, Xiaohang , LIU, Jian , LI, Jing
发明人： GUO, Chaohui , ZHONG, Xiaohang , LIU, Jian , LI, Jing
CPC分类号： B32B29/00 , B32B27/42 , B32B29/005 , B32B2250/26 , B32B2250/40 , B32B2260/028 , B32B2260/046 , B32B2307/306 , B32B2307/554 , B32B2307/714 , B32B2479/00
摘要： This invention discloses a three-layer-sandwich solid phenolic core (SPC) comprising first outside layer, middle layer and second outside layer. The middle layer of the SPC is a thick solid plate formed by using several layers of paper material through heat-pressing process; the first and second outside layers of the SPC are thin solid plates formed by using several layers of paper material through heat-pressing process; the three-layer-sandwich SPC is formed by coating adhesive on the outside surfaces of the middle layer (or the inner surfaces of the first and second outside layers) and then by pressing the first and second outside layers onto the outside surfaces of the middle layer. This invention is advantageous in increasing yield, increasing production elasticity, decreasing SPC cost and increasing the quality of the SPC.
摘要翻译：本发明公开了一种包含第一外层，中间层和第二外层的三层夹心固体酚醛芯（SPC）。 SPC的中间层是通过热压工艺使用几层纸材料形成的厚实心板; SPC的第一和第二外层是通过热压工艺使用数层纸材形成的薄的固体板; 通过将粘合剂涂覆在中间层（或第一和第二外层的内表面）的外表面上，然后通过将第一和第二外层压在中间层的外表面上而形成三层夹心SPC 层。本发明有利于提高产量，提高生产弹性，降低SPC成本，提高SPC质量。

2. 发明公开

EP2821801A1 MULTI-NODE SYNCHRONOUS ON-SITE TEST METHOD 审中-公开
标题翻译：同步MEHRKNOTEN-VORORT-TESTVERFAHREN
公开(公告)号：EP2821801A1
公开(公告)日：2015-01-07
申请号：EP12870235.4
申请日：2012-05-02
申请人： Jiangxi Electric Power Science Research Institute , Pei, Maolin , Sun, Ping , Zhang, Chunqiang , Liu, Jian , Hu, Haimei , Zhu, Ming
发明人： PEI, Maolin , SUN, Ping , ZHANG, Chunqiang , LIU, Jian , HU, Haimei , ZHU, Ming
IPC分类号： G01R31/00 , G01R35/00
CPC分类号： G01R31/40 , G01R21/133 , H02J13/0079
摘要： A multi-node synchronous on-site test method, the method comprising: using GPS time as time reference, and conducting synchronous on-site tests on the devices to be tested and systems distributed at different places at an appointed time; controlling the synchronous phase control simulation devices distributed at multiple nodes via a synchronous test control center; within a uniform time section, synchronously outputting secondary side AC simulation signals, and simulating various actual operating conditions, thus achieving the detection of the monitoring and control performances of various dynamic monitoring and control systems, and ensuring the normal functions of the systems. The method of the present invention is able to conduct multi-node dynamic simulation test with synchronized GPS time, and achieves the detection of large-area multi-node monitoring and control systems. The present invention is suitable for the test of a wide area measurement system (WAMS) function, the simulation test of a damping control function, the simulation test of transiently stable state analysis and control functions, the simulation test of voltage stabilization and control functions, the simulation test of an islanding control function, the simulation test of wide area protection system functions and the like.
摘要翻译：一种多节点同步现场测试方法，该方法包括：使用GPS时间作为时间参考，对要测试的设备进行同步现场测试，并在指定时间内在不同地点分配系统; 通过同步测试控制中心控制分布在多个节点的同步相位控制仿真设备; 在均匀时间段内同步输出二次侧交流模拟信号，模拟各种实际运行状况，实现对各种动态监控系统的监控性能的检测，确保系统的正常功能。本发明的方法能够以同步GPS时间进行多节点动态模拟测试，实现了大面积多节点监控系统的检测。本发明适用于广域测量系统（WAMS）功能的测试，阻尼控制功能的仿真测试，瞬态稳态分析和控制功能的仿真测试，稳压控制功能的仿真测试，孤岛控制功能的仿真测试，广域保护系统功能的仿真测试等。

3. 发明公开

EP1384022A2 NUCLEIC ACID AMPLIFICATION UTILIZING MICROFLUIDIC DEVICES 审中-公开
标题翻译：利用微流体装置的核酸扩增
公开(公告)号：EP1384022A2
公开(公告)日：2004-01-28
申请号：EP02763966.5
申请日：2002-04-05
申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY , Enzelberger, Markus M. , Hansen, Carl L. , Liu, Jian , Quake, Stephen R. , Ma, Chiem
发明人： ENZELBERGER, Markus, M. , HANSEN, Carl, L. , LIU, Jian , QUAKE, Stephen, R. , MA, Chiem
IPC分类号： F16K17/00 , F04B19/24 , F04B17/00 , F28D21/00 , C12M1/00 , C12P19/34 , C12Q1/68 , C23C16/00 , F27B5/14 , G01N21/01 , G01N27/26 , G01N27/447 , C07K1/04 , C07K17/06 , C07K17/14 , B01J19/00
CPC分类号： C12Q1/68 , B01F5/102 , B01F5/108 , B01F13/0059 , B01F15/06 , B01L3/50273 , B01L3/502738 , B01L7/525 , B01L9/527 , B01L2300/0861 , B01L2300/088 , B01L2300/0883 , B01L2300/0887 , B01L2300/123 , B01L2300/1822 , B01L2300/1827 , B01L2300/1838 , B01L2400/0481 , B01L2400/0655 , C12Q1/6844 , C12Q3/00 , C12Q2565/629
摘要： The present invention provides microfluidic devices and methods using the same in various types of thermal cycling reactions. Certaom devices include a rotary microfluidic channel and a plurality of temperature regions at different locations along the rotary microfluidic channel at which temperature is regulated. Solution can be repeatedly passed through the temperature regions such that the solution is exposed to different temperatures. Other microfluidic devices include an array of reaction chambers formed by intersecting vertical and horizontal flow channels, with the ability to regulate temperature at the reaction chambers. The microfluidic devices can be used to conduct a number of different analyses, including various primer extension reactions and nucleic acid amplification reactions.
摘要翻译：本发明提供了在各种类型的热循环反应中使用其的微流体装置和方法。 Certaom装置包括旋转微流体通道和沿着旋转微流体通道的不同位置处的多个温度区域，温度在该不同位置被调节。溶液可以重复通过温度区域，使溶液暴露于不同的温度。其他微流体装置包括通过相交的垂直和水平流动通道形成的反应室阵列，其具有调节反应室温度的能力。微流体装置可用于进行许多不同的分析，包括各种引物延伸反应和核酸扩增反应。

4. 发明申请

WO2020117626A1 4-AMINO OR 4-ALKOXY-SUBSTITUTED ARYL SULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS 审中-公开
公开(公告)号：WO2020117626A1
公开(公告)日：2020-06-11
申请号：PCT/US2019/063909
申请日：2019-12-02
申请人： MERCK SHARP & DOHME CORP. , BUNGARD, Christopher J. , CHEN, Helen Y. , COX, Jason M. , GUO, Liangqin , KELLY, Michael J. III , KIM, Ronald M. , LAYTON, Mark E. , LIU, Hong , LIU, Jian , PATEL, Mehul F. , PERKINS, James J. , WANG, Deping , WON, Walter , YU, Younong , ZHANG, Ting
发明人： BUNGARD, Christopher J. , CHEN, Helen Y. , COX, Jason M. , GUO, Liangqin , KELLY, Michael J. III , KIM, Ronald M. , LAYTON, Mark E. , LIU, Hong , LIU, Jian , PATEL, Mehul F. , PERKINS, James J. , WANG, Deping , WON, Walter , YU, Younong , ZHANG, Ting
IPC分类号： C07D495/04 , C12Q1/26
摘要： Disclosed are compounds of Formula (I), Formula (II), or a salt thereof: Formula (I) Formula (II) which compounds have properties for inhibiting Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula (I), Formula (II) or their salts, and methods of treating pain disorders, cough, and itch using the same.

5. 发明申请

WO2020092187A1 2-AMINO-N-PHENYL-NICOTINAMIDES AS NAV1.8 INHIBITORS 审中-公开
公开(公告)号：WO2020092187A1
公开(公告)日：2020-05-07
申请号：PCT/US2019/058251
申请日：2019-10-28
申请人： MERCK SHARP & DOHME CORP. , BRESLIN, Michael, J. , BUNGARD, Christopher James , CHOBANIAN, Harry, R. , JONES, Kristen, L. G. , LAYTON, Mark, E. , LIU, Jian , PERKINS, James, J. , SCHUBERT, Jeffrey William , STACHEL, Shawn, J. , SUEN-LAI, Linda, M. , WU, Zhe
发明人： BRESLIN, Michael, J. , BUNGARD, Christopher James , CHOBANIAN, Harry, R. , JONES, Kristen, L. G. , LAYTON, Mark, E. , LIU, Jian , PERKINS, James, J. , SCHUBERT, Jeffrey William , STACHEL, Shawn, J. , SUEN-LAI, Linda, M. , WU, Zhe
IPC分类号： A61K31/4425 , A61K31/167 , A61K31/44 , C07D213/06 , C07D213/20
摘要： Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are inhibitors of Na v 1.8 channel activity and may be useful in the treatment, prevention, management, amelioration, control and suppression of diseases mediated by Na v 1.8 channel activity. The compounds of the present invention may be useful in the treatment, prevention or management of pain disorders, cough disorders, acute itch disorders, and chronic itch disorders.

6. 发明申请

WO2014116504A1 BTK INHIBITORS 审中-公开
标题翻译： BTK抑制剂
公开(公告)号：WO2014116504A1
公开(公告)日：2014-07-31
申请号：PCT/US2014/011950
申请日：2014-01-17
申请人： MERCK SHARP & DOHME CORP. , WU, Hao , KIM, Ronald, M. , LIU, Jian , LIU, Shilan , YANG, Chundao , ZHENG, Shuling
发明人： WU, Hao , KIM, Ronald, M. , LIU, Jian , LIU, Shilan , YANG, Chundao , ZHENG, Shuling
IPC分类号： C07D213/75
CPC分类号： A61K45/06 , A61K31/4985 , A61K31/519 , C07D473/34 , C07D487/04 , C07D519/00
摘要： The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I or pharmaceutically acceptable salts thereof. Formula I or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds in the treatment of Btk mediated disorders.
摘要翻译：本发明提供根据式I的布鲁顿氏酪氨酸激酶（Btk）抑制剂化合物或其药学上可接受的盐。式I或其药学上可接受的盐或包含这些化合物的药物组合物及其在治疗中的用途。具体而言，本发明涉及Btk抑制剂化合物在治疗Btk介导的疾病中的用途。

7. 发明申请

WO2013063217A1 FUSED BICYCLIC OXAZOLIDINONE CETP INHIBITOR 审中-公开
标题翻译：熔融双相氧化硅酮CETP抑制剂
公开(公告)号：WO2013063217A1
公开(公告)日：2013-05-02
申请号：PCT/US2012/061842
申请日：2012-10-25
申请人： MERCK SHARP & DOHME CORP. , SHAO, Pengcheng Patrick , YE, Feng , VACHAL, Petr , SHA, Deyou , KATIPALLY, Revathi Reddy , LIU, Jian , SUN, Wanying
发明人： SHAO, Pengcheng Patrick , YE, Feng , VACHAL, Petr , SHA, Deyou , KATIPALLY, Revathi Reddy , LIU, Jian , SUN, Wanying
IPC分类号： C07D498/04 , A61K31/4188 , A61P9/10
CPC分类号： C07D498/04 , A61K31/424 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/506 , A61K45/06
摘要： Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis.
摘要翻译：具有式I结构的化合物，包括化合物的药学上可接受的盐，是CETP抑制剂，可用于培养HDL-胆固醇，降低LDL-胆固醇，以及用于治疗或预防动脉粥样硬化。

8. 发明申请

WO2013020589A1 ADJUSTABLE MASK 审中-公开
标题翻译：可调面膜
公开(公告)号：WO2013020589A1
公开(公告)日：2013-02-14
申请号：PCT/EP2011/063714
申请日：2011-08-09
申请人： APPLIED MATERIALS, INC. , SCHEER, Evelyn , HANIKA, Markus , LINDENBERG, Ralph , BENDER, Marcus , LOPP, Andreas , SCHWANITZ, Konrad , PIERALISI, Fabio , LIU, Jian
发明人： SCHEER, Evelyn , HANIKA, Markus , LINDENBERG, Ralph , BENDER, Marcus , LOPP, Andreas , SCHWANITZ, Konrad , PIERALISI, Fabio , LIU, Jian
IPC分类号： C23C14/04 , C23C16/04
CPC分类号： C23C14/042 , C23C16/042
摘要： An deposition apparatus for forming a deposition material layer on a substrate is described. The deposition apparatus includes a substrate support adapted for holding a substrate; and an edge (660) exclusion mask (640) for covering a periphery of the substrate (610) during layer deposition. The mask has at least one frame portion defining an aperture. The at least one frame portion of the mask is adapted for being moved (670,680) with respect to the substrate depending on the amount of deposition material deposited on the at least one frame portion of the mask. Further, a method for depositing a deposition material layer on a substrate using an edge exclusion mask is described.
摘要翻译：描述了用于在基板上形成沉积材料层的沉积装置。沉积设备包括适于保持衬底的衬底支撑件; 以及用于在层沉积期间覆盖衬底（610）的周边的边缘（660）排除掩模（640）。掩模具有限定孔的至少一个框架部分。掩模的至少一个框架部分适于相对于基板移动（670,680），这取决于沉积在掩模的至少一个框架部分上的沉积材料的量。此外，描述了使用边缘排除掩模在基板上沉积沉积材料层的方法。

9. 发明申请

WO2012044567A3 IMIDAZOLE DERIVATIVES 审中-公开
公开(公告)号：WO2012044567A3
公开(公告)日：2012-04-05
申请号：PCT/US2011/053213
申请日：2011-09-26
申请人： MERCK SHARP & DOHME CORP. , LIU, Jian , BALKOVEC, James, M. , KRIKORIAN, Arto, D. , GUIADEEN, Deodial , YANG, Ginger, Xu-Qiang , JIAN, Tianying , WU, Zhicai , YU, Yang , NARGUND, Ravi, P. , VACHAL, Petr
发明人： LIU, Jian , BALKOVEC, James, M. , KRIKORIAN, Arto, D. , GUIADEEN, Deodial , YANG, Ginger, Xu-Qiang , JIAN, Tianying , WU, Zhicai , YU, Yang , NARGUND, Ravi, P. , VACHAL, Petr
IPC分类号： A01N43/52
摘要： Described herein are compounds of Formula (I). The compounds of Formula (I) act as DGAT1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for hyperlipidemia, diabetes mellitus and obesity.

10. 发明申请

WO2010106432A2 DEPOSITION APPARATUS WITH HIGH TEMPERATURE ROTATABLE TARGET AND METHOD OF OPERATING THEREOF 审中-公开
标题翻译：具有高温可旋转目标的沉积装置及其操作方法
公开(公告)号：WO2010106432A2
公开(公告)日：2010-09-23
申请号：PCT/IB2010/000598
申请日：2010-03-19
申请人： APPLIED MATERIALS, INC. , MUELLER, Joachim , TRASSL, Roland , LIU, Jian
发明人： MUELLER, Joachim , TRASSL, Roland , LIU, Jian
IPC分类号： H01L21/203
CPC分类号： C23C14/34 , C23C14/3407 , C23C14/3421 , C23C14/35 , C23C14/541 , H01J37/32724 , H01J37/34 , H01J37/3405
摘要： A deposition apparatus (100) and a method for sputtering material on a substrate is provided with a substrate holder (110) for holding the substrate, a rotatable target (120) adapted for being sputtered, and a heating system including a back side heating (130) for heating the substrate from the back and a front side heating for heating the substrate from the front. The rotatable target acts as the front side heating and is adapted for heating the substrate to a temperature of at least 100°C.
摘要翻译：沉积设备（100）和在衬底上溅射材料的方法设置有用于保持衬底的衬底保持器（110），适于溅射的可旋转靶（120）和包括背侧加热（ 130），用于从背面加热基板和从前方加热基板的正面加热。可旋转的靶用作前侧加热，适于将基底加热到至少100℃的温度。

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