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1. 发明申请

WO2010120671A1 EVERTING DEPLOYMENT SYSTEM AND HANDLE 审中-公开
标题翻译：代表部署制度和手段
公开(公告)号：WO2010120671A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/030696
申请日：2010-04-12
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE APS , PARKER, Fred, T. , HANSEN, Palle, M.
发明人： PARKER, Fred, T. , HANSEN, Palle, M.
IPC分类号： A61F2/84
CPC分类号： A61F2/97 , A61F2/95 , A61F2/966 , A61F2002/9517 , A61F2002/9522 , A61F2250/0039 , A61L29/085
摘要： A stent deployment system, handle, and method of loading of a medical device are provided. The system includes an outer catheter having an inner liner extending past the end of the outer catheter and an inner catheter disposed within the outer catheter. The inner liner is inverted and attached to the inner catheter. Relative movement between the outer and the inner catheters can urge the inner liner to peel away from the medical device. A handle is disposed at the proximal end of the outer catheter, and may include a splitter configured to slice the wall of the tubular member. The handle may also include a rotatable mechanism that can be attached to the tubular member. Rotation of the rotatable mechanism retracts a portion of the tubular member into the handle and winds the sliced portion about the rotatable mechanism.
摘要翻译：提供了支架部署系统，手柄和装载医疗装置的方法。该系统包括具有延伸穿过外导管的端部的内衬套和设置在外导管内的内导管的外导管。内衬被倒置并连接到内导管上。外导管和内导管之间的相对运动可促使内衬从医疗装置剥离。手柄设置在外导管的近端处，并且可以包括被配置为切割管状构件的壁的分流器。手柄还可以包括可连接到管状构件的可旋转机构。可旋转机构的旋转将管状构件的一部分缩回到手柄中并围绕可旋转机构卷绕切片部分。

2. 发明申请

WO2008070130A1 METHOD FOR LOADING MEDICAL DEVICE INTO A DELIVERY SYSTEM 审中-公开
标题翻译：将医疗装置装载到传送系统中的方法
公开(公告)号：WO2008070130A1
公开(公告)日：2008-06-12
申请号：PCT/US2007/024932
申请日：2007-12-04
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE ApS , MAGNUSON, Mark, A. , PARKER, Fred, T. , HANSEN, Palle, M.
发明人： MAGNUSON, Mark, A. , PARKER, Fred, T. , HANSEN, Palle, M.
IPC分类号： A61F2/82 , C22F1/00 , C22F1/10
CPC分类号： C22F1/006 , A61F2/95 , A61F2002/9522 , A61F2210/0014 , A61F2250/0042 , C22F1/00 , C22F1/10 , Y10T29/4976 , Y10T29/49865
摘要： A process to load a medical device comprising a shape memory material into a delivery system is described herein. According to one aspect, the method includes applying a force to the medical device to obtain a delivery configuration thereof, where the device is at a first temperature within an R-phase temperature range of the shape memory material during application of the force. The medical device is cooled in the delivery configuration to a second temperature at or below a martensite finish temperature of the shape memory material. The force is then removed from the medical device, and the device is loaded into a delivery system. Preferably, the medical device substantially maintains the delivery configuration during the loading process.
摘要翻译：本文描述了将包括形状记忆材料的医疗装置加载到递送系统中的过程。根据一个方面，所述方法包括向所述医疗装置施加力以获得其输送构型，其中所述装置在所述力的施加期间处于所述形状记忆材料的R相温度范围内的第一温度。医疗装置在输送构型中被冷却到等于或低于形状记忆材料的马氏体终止温度的第二温度。然后将力从医疗装置中取出，将装置装载到输送系统中。优选地，医疗装置在装载过程中基本维持输送构型。

3. 发明申请

WO2003030786A2 CANNULA STENT 审中-公开
公开(公告)号：WO2003030786A2
公开(公告)日：2003-04-17
申请号：PCT/US2002/032338
申请日：2002-10-09
申请人： WILLIAM COOK EUROPE APS , COOK INCORPORATED
发明人： HANSEN, Palle, M. , PARKER, Fred, T. , EHRLINSPIEL, Michael
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2230/0054
摘要： A stent (30) formed from cannula and having flexible segments (31) and high hoop strength segments (32) alternating therealong. Longitudinal struts or tie bars (41) interconnect the segments. Minimal length reduction of the strut occurs upon expansion. In the high hoop strength segment (32), struts (37) in a zig-zag configuration (Gianturco Z-stent) are initially parallel in the unexpanded strut condition. In the flexible segment (31), struts (58) extend from a respective C shaped bend (59) to converge at the opposite ends thereof when unexpanded. In one embodiment, certain adjacent struts (39-41) of the hoop segment are spaced apart by elongated openings or gaps (46, 48) interposed therebetween and interconnected at their respective ends (42, 44) to form a T-shaped strut interconnection (45). The selected width (50, 51) of the first and third struts (54, 57) increases toward the ends (47, 48) of the elongated openings (46, 48) adjacent the strut interconnection (45). This strut width increase about one end of the strut significantly reduces the tensile strain exhibited about the opening end when the stent is radially expanded during manufacture. The tip length (52, 55) of the struts about the interconnection (45) is also adjusted (increased) along with the other C-shaped strut interconnections (59, 71) to further distribute the tensile strain developed during radial expansion.
摘要翻译：支架（30）由插管形成并且具有柔性片段（31）和沿其交替的高环箍强度片段（32）。纵向支柱或连杆（41）将这些部分互连。扩张时最小长度减少。在高箍强度段（32）中，呈Z字形构造的支柱（37）（Gianturco Z-支架）最初平行于未膨胀支柱状态。在柔性部分（31）中，当未扩张时，支柱（58）从相应的C形弯曲部（59）延伸以会聚在其相对端处。在一个实施例中，箍段的某些相邻支柱（39-41）由插入其间的细长开口或间隙（46,48）间隔开并且在其相应端部（42,44）处互连以形成T形支柱互连（45）。第一和第三支柱（54,57）的选定宽度（50,51）朝向邻近支柱互连（45）的细长开口（46,48）的端部（47,48）增大。当支架在制造期间径向膨胀时，围绕支杆的一端的该支杆宽度增加显着减小了关于开口端所展现的拉伸应变。围绕互连（45）的支柱的尖端长度（52,55）也与其他C形支柱互连（59,71）一起被调整（增大），以进一步分布在径向膨胀期间产生的拉伸应变。 p>

4. 发明申请

WO2010120670A1 INTRODUCER APPARATUS 审中-公开
标题翻译：介绍设备
公开(公告)号：WO2010120670A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/030695
申请日：2010-04-12
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE APS , HANSEN, Palle, M. , PARKER, Fred, T.
发明人： HANSEN, Palle, M. , PARKER, Fred, T.
IPC分类号： A61F2/84
CPC分类号： A61F2/966 , A61F2/95 , A61F2/97 , A61F2002/9517
摘要： A stent introducer apparatus comprises a sheath for surrounding a stent member, with the sheath having a longitudinal slit extending from one end along at least a substantial part of the length thereof, and a sheath withdrawal device comprising a reel for winding up the sheath. A second sheath may surround the slit portion of the sheath. An intermediate guide member can smooth the withdrawal procedure and flatten the sheath before it is wound on the reel. The intermediate guide member may include at least one of a second reel or a slot-defining member. The reel may be operated by means of a gear system. A method of deploying a stent member is also provided.
摘要翻译：支架引入装置包括用于围绕支架构件的护套，护套具有沿其长度的至少大部分的一端延伸的纵向狭缝，以及包括用于卷绕护套的卷轴的护套取出装置。第二护套可以围绕护套的狭缝部分。中间引导构件可以使护套平滑并且在将其卷绕在卷轴之前使其平坦化。中间引导构件可以包括第二卷轴或槽限定构件中的至少一个。卷轴可以通过齿轮系统来操作。还提供了展开支架构件的方法。

5. 发明公开

EP1434540A2 CANNULA STENT 有权
公开(公告)号：EP1434540A2
公开(公告)日：2004-07-07
申请号：EP02773734.5
申请日：2002-10-09
申请人： William Cook Europe ApS , Cook Incorporated
发明人： HANSEN, Palle, M. , PARKER, Fred, T. , EHRLINSPIEL, Michael
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2230/0054
摘要： A stent (30) formed from cannula and having flexible segments (31) and high hoop strength segments (32) alternating therealong. Longitudinal struts or tie bars (41) interconnect the segments. Minimal length reduction of the strut occurs upon expansion. In the high hoop strength segment (32), struts (37) in a zig-zag configuration (Gianturco Z-stent) are initially parallel in the unexpanded strut condition. In the flexible segment (31), struts (58) extend from a respective C shaped bend (59) to converge at the opposite ends thereof when unexpanded. In one embodiment, certain adjacent struts (39-41) of the hoop segment are spaced apart by elongated openings or gaps (46, 48) interposed therebetween and interconnected at their respective ends (42, 44) to form a T-shaped strut interconnection (45). The selected width (50, 51) of the first and third struts (54, 57) increases toward the ends (47, 48) of the elongated openings (46, 48) adjacent the strut interconnection (45). This strut width increase about one end of the strut significantly reduces the tensile strain exhibited about the opening end when the stent is radially expanded during manufacture. The tip length (52, 55) of the struts about the interconnection (45) is also adjusted (increased) along with the other C-shaped strut interconnections (59, 71) to further distribute the tensile strain developed during radial expansion.
摘要翻译：由插管形成的支架（30）具有沿其交替的柔性段（31）和高环箍强度段（32）。纵向支柱或连杆（41）将这些部分互连。扩张时最小长度减少。在高箍强度段（32）中，呈Z字形构造的支柱（37）（Gianturco Z-支架）最初平行于未膨胀支柱状态。在柔性部分（31）中，当未扩张时，支柱（58）从相应的C形弯曲部（59）延伸以会聚在其相对端处。在一个实施例中，箍段的某些相邻支柱（39-41）由插入其间的细长开口或间隙（46,48）间隔开并且在其相应端部（42,44）处互连以形成T形支柱互连（45）。第一和第三支柱（54,57）的选定宽度（50,51）朝向邻近支柱互连（45）的细长开口（46,48）的端部（47,48）增大。当支架在制造期间径向膨胀时，围绕支杆的一端的该支杆宽度增加显着减小了关于开口端所展现的拉伸应变。围绕互连（45）的支柱的尖端长度（52,55）也与其他C形支柱互连（59,71）一起被调整（增加），以进一步分布在径向扩张期间产生的拉伸应变。

6. 发明授权

EP1434540B1 CANNULA STENT 有权
标题翻译： KANÜLENFORMIGER支架术
公开(公告)号：EP1434540B1
公开(公告)日：2006-07-19
申请号：EP02773734.5
申请日：2002-10-09
申请人： WILLIAM COOK EUROPE ApS , Cook Incorporated
发明人： HANSEN, Palle, M. , PARKER, Fred, T. , EHRLINSPIEL, Michael
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91575 , A61F2230/0054
摘要： A stent (30) formed from cannula and having flexible segments (31) and high hoop strength segments (32) alternating therealong. Longitudinal struts or tie bars (41) interconnect the segments. Minimal length reduction of the strut occurs upon expansion. In the high hoop strength segment (32), struts (37) in a zig-zag configuration (Gianturco Z-stent) are initially parallel in the unexpanded strut condition. In the flexible segment (31), struts (58) extend from a respective C shaped bend (59) to converge at the opposite ends thereof when unexpanded. In one embodiment, certain adjacent struts (39-41) of the hoop segment are spaced apart by elongated openings or gaps (46, 48) interposed therebetween and interconnected at their respective ends (42, 44) to form a T-shaped strut interconnection (45). The selected width (50, 51) of the first and third struts (54, 57) increases toward the ends (47, 48) of the elongated openings (46, 48) adjacent the strut interconnection (45). This strut width increase about one end of the strut significantly reduces the tensile strain exhibited about the opening end when the stent is radially expanded during manufacture. The tip length (52, 55) of the struts about the interconnection (45) is also adjusted (increased) along with the other C-shaped strut interconnections (59, 71) to further distribute the tensile strain developed during radial expansion.

7. 发明申请

WO2008112242A2 WOVEN FABRIC WITH SHAPE MEMORY ELEMENT STRANDS 审中-公开
标题翻译：具有形状记忆元件的WOVEN织物
公开(公告)号：WO2008112242A2
公开(公告)日：2008-09-18
申请号：PCT/US2008/003251
申请日：2008-03-12
申请人： COOK INCORPORATED , CARLSON, James, M. , KUPPURATHANAM, Shyam , PARKER, Fred, T. , TODD, Rebecca, S.
发明人： CARLSON, James, M. , KUPPURATHANAM, Shyam , PARKER, Fred, T. , TODD, Rebecca, S.
IPC分类号： A61L31/02 , A61L31/04 , A61L31/14
CPC分类号： A61F2/90 , A61F2/06 , A61F2/07 , A61F2002/075 , A61F2210/0014 , A61L31/022 , A61L31/041 , A61L31/14 , A61L2400/16 , C08L2201/12 , D02G3/12 , D02G3/448 , D03D3/02 , D03D13/004 , D03D13/008 , D03D15/00 , D03D15/08 , D10B2101/20 , D10B2321/021 , D10B2321/022 , D10B2321/042 , D10B2331/04 , D10B2331/10 , D10B2401/046 , D10B2401/061 , D10B2509/06
摘要： A woven fabric for use in an implantable medical device, such as a stented graft member, comprises shape memory element strands (100) woven with textile strands (110, 115). At least one of the shape memory element strands (100) has at least one float of at least five textile strands between binding points. The shape memory element strands may be heated and cooled before the weaving process, and then heated again after the weaving process.
摘要翻译：用于可植入医疗装置（例如支架移植物构件）中的机织织物包括用织物股线（110,115）编织的形状记忆元件股线（100）。至少一个形状记忆元件股线（100）在结合点之间具有至少一个至少五个纺织股线的浮子。形状记忆元件股线可以在织造过程之前被加热和冷却，然后在织造过程之后再次加热。

8. 发明申请

WO2006031874A1 LARGE DIAMETER SHEATH 审中-公开
标题翻译：大直径的沙子
公开(公告)号：WO2006031874A1
公开(公告)日：2006-03-23
申请号：PCT/US2005/032716
申请日：2005-09-14
申请人： WILLIAM A. COOK AUSTRALIA PTY. LTD. , COOK INCORPORATED , HARTLEY, David, Ernest , DREWES, David, A., Jr. , PARKER, Fred, T. , DITTMAN, Jay, A.
发明人： HARTLEY, David, Ernest , DREWES, David, A., Jr. , PARKER, Fred, T. , DITTMAN, Jay, A.
IPC分类号： A61M25/06 , A61M25/00
CPC分类号： A61F2/95 , A61F2/966 , A61M25/005 , A61M25/0053 , A61M25/0662 , A61M2025/0059
摘要： A large diameter, flexible, kink-resistant and rotatable introducer sheath (10) for percutaneous delivery of a contained and implantable medical device in the vasculature of a patient. The introducer sheath includes a reinforcement such as a flat wire coil (23) fitted about an inner, lubricous material such as polytetrafluoroethylene tube (22). A wire braid (25) is placed around the coil to give good transfer of rotational forces. An outer tube (27) of a heat formable polyamide material is heat formed and compressed through the spaces between the wires of the braid and turns of the wire coil to mechanically connect the outer tube to the roughened outer surface of the inner tube. The durometer of the outer tube can be varied to effect the flexibility of the sheath. A radiopaque marker (42) is positioned at the distal end of the coil and around the inner tube for radiographic visualization.
摘要翻译：用于经皮递送患者脉管系统中的容纳和可植入的医疗装置的大直径的，柔性的，扭结的和扭转的导引套（10）。引导器护套包括诸如扁丝线圈（23）之类的加强件，该扁线线圈围绕诸如聚四氟乙烯管（22）的内部润滑材料安装。线圈编织物（25）围绕线圈放置，以提供良好的转动力传递。可热成型的聚酰胺材料的外管（27）通过编织线的线间和线圈的匝之间的空间被热形成和压缩，以将外管机械地连接到内管的粗糙的外表面。可以改变外管的硬度以影响护套的柔性。不透射线的标记（42）位于线圈的远端并且围绕内管定位用于放射照相可视化。

9. 发明申请

WO2010021908A1 INTRODUCER SHEATH HAVING DUAL REINFORCING ELEMENTS 审中-公开
标题翻译：介绍具有双重增强元素的树脂
公开(公告)号：WO2010021908A1
公开(公告)日：2010-02-25
申请号：PCT/US2009/053701
申请日：2009-08-13
申请人： COOK INCORPORATED , PARKER, Fred, T. , CRABTREE, Christopher, B.
发明人： PARKER, Fred, T. , CRABTREE, Christopher, B.
IPC分类号： A61M25/00
CPC分类号： A61M25/005 , A61M25/0045 , A61M25/0053
摘要： An introducer sheath for deploying a stent to a target site within a body passageway of a patient. The introducer sheath includes a tubular inner liner having a proximal portion, a distal portion, and an outer surface. A first reinforcing element, and a second reinforcing element are positioned along the outer surface of the inner liner. The first reinforcing element comprises a braid the second reinforcing element comprises a coil. The braid is positioned at the proximal portion of the inner liner and extends distally therefrom. The coil is positioned at the distal portion longitudinally adjacent the braid. The braid has a length that may extend about 90% of the length of the sheath. An outer jacket is positioned longitudinally around the reinforcing elements, and is connected to the inner liner between the respective wires of the braid and the coil.
摘要翻译：用于将支架部署到患者的身体通道内的目标部位的引导器护套。引导器护套包括具有近端部分，远侧部分和外表面的管状内衬。第一增强元件和第二加强元件沿着内衬的外表面定位。第一增强元件包括编织物，第二增强元件包括线圈。编织物定位在内衬的近端部分并从其向远侧延伸。线圈定位在纵向部分的纵向附近的编织物处。编织物的长度可以延伸到护套长度的大约90％。外护套围绕加强元件纵向定位，并且连接到编织物和线圈的各个线之间的内衬。

10. 发明申请

WO2007059349A1 FOAM EMBOLIC PROTECTION DEVICE 审中-公开
标题翻译：泡沫保护装置
公开(公告)号：WO2007059349A1
公开(公告)日：2007-05-24
申请号：PCT/US2006/044928
申请日：2006-11-17
申请人： COOK INCORPORATED , MAGNUSON, Mark, A. , PARKER, Fred, T.
发明人： MAGNUSON, Mark, A. , PARKER, Fred, T.
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61L31/022 , A61L31/146 , A61L2400/16
摘要： An embolic protection device includes a foam body attached to a plurality of flexible struts. The foam body has a generally conical geometry and the bottom of the conical geometry having a generally conical recess. The filter portion has pores sized such that blood cells can pass through the foam body, but larger material such as objects would be trapped in the recess. Each strut is attached along the periphery of the foam body and extend from the first end of the foam body to a connection point located proximate the first end.
摘要翻译：栓塞保护装置包括附接到多个柔性支柱的泡沫体。泡沫体具有大致圆锥形的几何形状，圆锥形几何形状的底部具有大致锥形的凹部。过滤器部分具有尺寸使得血细胞可以通过泡沫体的孔，但是更大的材料例如物体将被困在凹部中。每个支柱沿着泡沫体的周边附着并且从泡沫体的第一端延伸到靠近第一端的连接点。

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