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1. 发明申请

WO2005091936A2 HIGH PERFORMANCE LIQUID CHROMATOGRAPHY SAMPLE INTRODUCTION OPTIMIZED WITH BUBBLE DETECTION 审中-公开
标题翻译：高性能液相色谱样品介绍优化与泡沫检测
公开(公告)号：WO2005091936A2
公开(公告)日：2005-10-06
申请号：PCT/US2005006719
申请日：2005-03-02
申请人： WATERS INVESTMENTS LTD , USOWICZ JAMES E , BEALS PEYTON C , KEENE RUSSELL , KENT RICHARD , SOARES MIGUEL , JOHN HEDEN
发明人： USOWICZ JAMES E , BEALS PEYTON C , KEENE RUSSELL , KENT RICHARD , SOARES MIGUEL , JOHN HEDEN
IPC分类号： G01N21/53 , G01N30/32
CPC分类号： G01N21/53 , G01N30/32 , G01N2030/207
摘要： Disclosed herein is a device for detecting a condition in a fluid system and initiating a response based on the condition. The device consists of a sensor that responds to a first and second condition of the fluid in the system and a control means that receives the responses and generates command signals in based on the received response. In a liquid chromatography system, the device is used to determine the volume of components of the fluid system. In addition, the device allow leaks to be detected and permits the fluid in the system to be transported at a optimum speed. The device is well implemented utilizing to a light emitter and light receptor that are sensitive to the fluid in either a gaseous or liquid state.
摘要翻译：本文公开了一种用于检测流体系统中的状况并基于该条件启动响应的装置。该装置包括响应系统中的流体的第一和第二状态的传感器以及基于所接收的响应接收响应并产生命令信号的控制装置。在液相色谱系统中，该装置用于确定流体系统的部件的体积。此外，该装置允许检测泄漏，并允许系统中的流体以最佳速度被输送。该装置利用对气体或液态的流体敏感的光发射器和光接收器良好地实现。

2. 发明申请

WO2005047826A2 A DEVICE AND METHOD FOR CONTROLLING THE FLOW OF FLUID IN A CONDUIT 审中-公开
标题翻译：用于控制流体中流体流动的装置和方法
公开(公告)号：WO2005047826A2
公开(公告)日：2005-05-26
申请号：PCT/US2004037640
申请日：2004-11-10
申请人： WATERS INVESTMENTS LTD , KEENE RUSSELL , MOELLER MARK , CIOLKOSZ THEODORE
发明人： KEENE RUSSELL , MOELLER MARK , CIOLKOSZ THEODORE
IPC分类号： F16K11/07 , G01F20060101 , G01N30/20 , G01N30/32 , G01N30/36 , G01F
CPC分类号： G01N30/36 , F16K11/07 , F16K41/043 , G01N2030/202 , G01N2030/328 , Y10T137/8242 , Y10T137/86501 , Y10T137/86863
摘要： The present invention provides devices and methods for controlling the flow of fluids in very high pressure situations. The devices feature valve shafts having bearings and pins to hold stator surfaces and rotor surfaces in proper alignment.
摘要翻译：本发明提供用于控制在非常高压力情况下的流体流动的装置和方法。这些装置具有带有轴承和销的阀轴，用于保持定子表面和转子表面的正确对准。

3. 发明申请

WO2005079543A3 PIN VALVE ASSEMBLY 审中-公开
标题翻译：引导阀组件
公开(公告)号：WO2005079543A3
公开(公告)日：2007-03-29
申请号：PCT/US2005005714
申请日：2005-02-18
申请人： WATERS INVESTMENTS LTD , KEENE RUSSELL , FRISWELL DAVID R , MOELLER MARK , MURPHY CHARLES , CIOLKOSZ THEODORE D
发明人： KEENE RUSSELL , FRISWELL DAVID R , MOELLER MARK , MURPHY CHARLES , CIOLKOSZ THEODORE D
IPC分类号： B01D15/08 , G01N30/04 , G01N30/20
CPC分类号： G01N30/20 , G01N30/22 , G01N2030/201 , G01N2030/202 , G01N2030/204 , G01N2030/207 , Y10T137/87249 , Y10T137/87692 , Y10T137/87708 , Y10T137/87788
摘要： A pin valve assembly and a method of controlling the flow of fluids comprising a pin block housing pin valves, a fluid plate with a fluid channel for fluidically communicating with the pin valves, and a fitting block housing fittings for fluidic communication with the fluid plate and for fluidic communication with fluidic components. The fluid flow through the channels of the fluid plate are controlled by the fluidic components and the pin valves.
摘要翻译：一种针阀组件和一种控制流体流动的方法，该流体组件包括销块容纳销阀，具有用于与销阀流体连通的流体通道的流体板，以及用于与流体板流体连通的配合块壳体配件，以及用于与流体组分的流体连通。通过流体板的通道的流体流动由流体组件和销阀控制。

4. 发明申请

WO2005084337A3 A SELF-SETTING HIGH PRESSURE FITTING 审中-公开
标题翻译：自设高压配件
公开(公告)号：WO2005084337A3
公开(公告)日：2006-01-12
申请号：PCT/US2005006755
申请日：2005-03-02
申请人： WATERS INVESTMENTS LTD , KEENE RUSSELL
发明人： KEENE RUSSELL
IPC分类号： F16L25/00 , F16L35/00
CPC分类号： F16L15/009 , G01N30/6026
摘要： A coupling element (1) comprising a male sealing element (5) is disclosed herein. The male sealing element comprises a first end (7), second end (9), and a longitudinal axis extending between the first and second end. The coupling element is housed within a nut (3). In one aspect, the male sealing element has a generally cylindrical shape. Also, the male sealing element defines a fluid passageway therethrough for the transmission of fluid. The male sealing element is secured to a ferrule (13) which is located within a cavity of the nut. The first end of the male sealing element defines a conical sealing surface. In one aspect, the male conical sealing surface (17) mates with a female sealing element (23) which has a receptacle that is defined by a nearly complementary conical geometry. In this aspect, the male conical sealing surface has a mismatched angle when compared to the complementary conical female sealing element. The coupling element also has a biasing element (19) disposed between a retaining ring and the ferrule located within the nut cavity. This biasing element facilitates a fluid-tight, metal to metal (or metal to plastic, or plastic to plastic) seal between the male sealing element and female sealing element.
摘要翻译：本文公开了包括阳密封元件（5）的联接元件（1）。阳密封元件包括第一端（7），第二端（9）和在第一端和第二端之间延伸的纵向轴线。联接元件容纳在螺母（3）内。在一个方面，阳密封元件具有大致圆柱形形状。此外，阳密封元件限定了通过其的流体通道用于流体的传输。阳密封元件固定到位于螺母的腔内的套圈（13）。阳密封元件的第一端限定锥形密封表面。在一个方面，阳锥形密封表面（17）与阴密封元件（23）配合，阴密封元件（23）具有由几乎互补的圆锥形几何形状限定的容座。在这个方面，与互补锥形阴密封元件相比，阳锥形密封表面具有不匹配的角度。联接元件还具有设置在保持环和位于螺母腔内的套圈之间的偏置元件（19）。该偏置元件有助于在阳密封元件和阴密封元件之间的流体密封的金属对金属（或金属对塑料或塑料到塑料）的密封。

5. 发明申请

WO2005091938A3 FLOW THROUGH ISOLATION VALVE FOR HIGH PRESSURE FLUIDS 审中-公开
标题翻译：通过用于高压流体的隔离阀流动
公开(公告)号：WO2005091938A3
公开(公告)日：2006-03-16
申请号：PCT/US2005006764
申请日：2005-03-02
申请人： WATERS INVESTMENTS LTD , KEENE RUSSELL , FRISWELL DAVID R
发明人： KEENE RUSSELL , FRISWELL DAVID R
IPC分类号： F16K5/04 , F16K11/076 , F16K31/00
CPC分类号： F16K11/0853 , F16K5/0428 , F16K11/076 , G01N30/28 , Y10T137/86863 , Y10T137/86871 , Y10T137/87161
摘要： A flow through isolation valve having a stationary member; a movable member, with a surface of the stationary member interfacing with a surface of the movable member; and at least one pin isolation valve. The pin isolation valve has a flow through internal conduit and is movable so that the internal conduit can fluidically communicate with at least one blank opening in the movable member and with a flow through internal conduit in the movable member. Movement is by rotation, linear or curvilinear translation. At least one pin isolation valve is fluidically coupled typically to a sample loop of a face seal valve, or to a pump supplying high pressure liquid to or to a column discharging liquid from a face seal valve of a high pressure liquid chromatography (HPLC) system or directly to the face seal valve.
摘要翻译：具有静止构件的通过隔离阀的流动; 可动构件，其中所述固定构件的表面与所述可动构件的表面相接合; 和至少一个针式隔离阀。针式隔离阀具有通过内部导管的流动并且可移动，使得内部导管可与可移动构件中的至少一个坯件开口流动连通，并且流过可移动构件中的内部导管。运动是通过旋转，线性或曲线翻译。至少一个针式隔离阀通常流体耦合到面密封阀的样品回路，或者向从高压液相色谱（HPLC）系统的面密封阀排出液体的柱提供高压液体的泵或直接到面密封阀。

6. 发明申请

WO2005091924A3 PRESSURE MONITOR OPTIMIZATION OF FLUID PATH UTILIZATION 审中-公开
标题翻译：流体路径利用压力监测优化
公开(公告)号：WO2005091924A3
公开(公告)日：2005-11-10
申请号：PCT/US2005006673
申请日：2005-03-02
申请人： WATERS INVESTMENTS LTD , CIOLKOSZ THEODORE D , USOWICZ JAMES E , BEALS PEYTON C , KEENE RUSSELL
发明人： CIOLKOSZ THEODORE D , USOWICZ JAMES E , BEALS PEYTON C , KEENE RUSSELL
IPC分类号： G01M3/26
CPC分类号： G01M3/02 , B01D15/14 , B01D15/163 , G01N11/00 , G01N30/24 , G01N30/32
摘要： A device comprising a pressure monitor and a control means that receives a signal representing measured pressure at the pressure monitor and controls the controllable elements of a fluid system is utilized to monitor a fluid system for error conditions, to optimize operations and to diagnose the fluid system. By following a testing protocol that selectively enables parts of the system, the control means narrows the list of possible failing components. Comparing the measured pressure against normal pressures allows the device to identify error conditions. Determining the volume of fluid being transported and controlling the duration of the flow optimizes operation of the fluid system.
摘要翻译：包括压力监测器和接收表示压力监测器处的测量压力的信号并控制流体系统的可控元件的信号的控制装置被用于监测流体系统的错误状况，以优化操作并诊断流体系统。通过遵循有选择地启用系统部分的测试协议，控制手段缩小了可能发生故障的组件的列表。将测量的压力与正常压力进行比较可以使设备识别错误状况。确定正在运输的流体的体积并控制流动的持续时间可优化流体系统的运行。

7. 发明申请

WO2005089124A2 COMBINATION FLOW THROUGH INJECTION AND ISOLATION VALVE FOR HIGH PRESSURE FLUIDS 审中-公开
标题翻译：通过高压流体注入和隔离阀组合流动
公开(公告)号：WO2005089124A2
公开(公告)日：2005-09-29
申请号：PCT/US2005007005
申请日：2005-03-04
申请人： WATERS INVESTMENTS LTD , KEENE RUSSELL
发明人： KEENE RUSSELL
IPC分类号： F16K11/085
CPC分类号： F16K11/0856 , B01D15/14 , G01N30/20 , G01N30/22 , Y10T137/86863
摘要： A flow through injection valve having a stationary member, a movable member, a surface of the stationary member interfacing with a surface of the movable member; and at least one pin isolation valve having a flow through internal conduit and movably positioned so that the internal conduit can interface with at least one flow through conduit in the movable member. The pin isolation valves are movably positioned so that the internal conduit is also capable of fluidically communicating with another flow through internal conduit in the movable member. The flow through injection valve can be combined with a similar flow through isolation valve to serve as a multiple valve and typically for replacing a conventional face seal valve of a high pressure liquid chromatography (HPLC) system. The multiple valve allows flow to be transferred through without need for switching or rotating under high pressure. Movement is by rotation or translation.
摘要翻译：具有固定构件，可动构件，与所述可动构件的表面接合的所述固定构件的表面的流过注射阀; 以及至少一个销隔离阀，其具有通过内部导管的流动并且可移动地定位，使得内部导管可与通过可移动构件中的导管的至少一个流体相接合。销隔离阀可移动地定位，使得内部导管也能够与通过可移动构件中的内部导管的另一流体流体连通。通过注射阀的流动可以与通过隔离阀的类似流体组合以用作多个阀，并且通常用于替换高压液相色谱（HPLC）系统的常规面密封阀。多个阀允许流动通过而不需要在高压下切换或旋转。运动是通过旋转或翻译。

8. 发明专利

GB2429265B Flow through isolation valve for high pressure fluids 未知
公开(公告)号：GB2429265B
公开(公告)日：2009-07-01
申请号：GB0619511
申请日：2005-03-02
申请人： WATERS INVESTMENTS LTD
发明人： KEENE RUSSELL , FRISWELL DAVID R
IPC分类号： F16K11/06 , F16K5/04 , F16K11/076

9. 发明专利

GB2431122B Pin valve assembly 未知
公开(公告)号：GB2431122B
公开(公告)日：2009-06-10
申请号：GB0615724
申请日：2005-02-18
申请人： WATERS INVESTMENTS LTD
发明人： KEENE RUSSELL , FRISWELL DAVID R , MOELLER MARK , MURPHY CHARLES , CIOLKOSZ THEODORE D
IPC分类号： G01N30/22 , B01D15/14 , G01N30/16 , G01N30/20

10. 发明专利

DE112005000428T5 未知
公开(公告)号：DE112005000428T5
公开(公告)日：2007-01-18
申请号：DE112005000428
申请日：2005-03-02
申请人： WATERS INVESTMENTS LTD
发明人： CIOLKOSZ THEODORE D , MCCORMICK DANIEL J , MURPHY CHARLES , LUONGO JOSEPH A , KEENE RUSSELL , DOURDEVILLE THEODORE , FRISWELL DAVID , KIRBY PETER , MOELLER MARK
IPC分类号： F04B39/10 , F04B53/10 , F16K15/04 , F16K25/00
摘要： In various embodiments a fluid control device suitable for high pressure analytical instruments includes a housing having an interior surface with an end wall. The interior surface defines a chamber. A valve assembly disposed in the chamber controls the flow of fluid through the chamber. An end cap is disposed in the housing opposite the end wall to enclose the chamber. The end wall and end cap each have an opening to pass a fluid to the chamber or to remove a fluid from the chamber. The housing and end cap each has an abutment surface to receive the other abutment surface. At least one of the abutment surfaces has a plastic seal coating. A means of compression, such as a compression housing and compression sleeve, is included to engage the end cap to deform the plastic seal coating between the abutment surfaces and thereby seal the chamber.

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