专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2008030931A2 METHODS OF TREATING TENDONITIS IN A SUBJECT BY USING AN ANTI-CYTOKINE AGENT 审中-公开
标题翻译：使用抗细胞因子治疗受试者中的肌腱炎的方法
公开(公告)号：WO2008030931A2
公开(公告)日：2008-03-13
申请号：PCT/US2007/077720
申请日：2007-09-06
申请人： WARSAW ORTHOPEDIC, INC. , ZANELLA, John M.
发明人： ZANELLA, John M.
IPC分类号： A61K39/39
CPC分类号： C07K16/24 , A61K2039/505
摘要： A method for treating tendonitis and bursitis in a subject involves providing an effective amount of an anti-cytokine agent to a musculo-tendinious structure. Anti-cytokine agents, such as, TNF-α inhibitors, NF-B inhibitors, IL-1 inhibitors, IL-6 inhibitors, IL-8 inhibitors, IL-12 inhibitors, IL-15 inhibitors, IL-10, Interferon-gamma (IFN-gamma) act to prevent further inflammation initiated by cytokine factors. One embodiment includes, adding with the anti-cytokine agent one or more of an antibiotic or analgesic. Delivery of the anti-cytokine agent may be provided to the affected musculo-tendinious structure by injection, implantation, or a transdermal patch. These agents, individually or in combination directly address the underlying causes of tendonitis, bursitis and associated tendinopathies that result in inflammation and pain.
摘要翻译：治疗受试者的肌腱炎和粘液囊炎的方法涉及向肌肉腱结构提供有效量的抗细胞因子试剂。抗细胞因子试剂，例如TNF-α抑制剂，NF-B抑制剂，IL-1抑制剂，IL-6抑制剂，IL-8抑制剂，IL-12抑制剂，IL-15抑制剂，IL-10，干扰素-γ （IFN-γ）起到防止细胞因子引发的进一步炎症的作用。一个实施方案包括添加抗细胞因子试剂中的一种或多种抗生素或止痛剂。可通过注射，植入或透皮贴剂将抗细胞因子试剂递送至受影响的肌腱结构。这些药物单独或组合直接解决导致炎症和疼痛的肌腱炎，滑囊炎和相关腱病的根本原因。

2. 发明申请

WO2008063949A2 SURFACE TREATMENTS OF AN ALLOGRAFT TO IMPROVE BINDING OF GROWTH FACTORS AND CELLS 审中-公开
标题翻译：用于改善生长因子和细胞结合的ALLOGRAFT的表面处理
公开(公告)号：WO2008063949A2
公开(公告)日：2008-05-29
申请号：PCT/US2007/084411
申请日：2007-11-12
申请人： WARSAW ORTHOPEDIC, INC. , MCKAY, William F. , ZANELLA, John M.
发明人： MCKAY, William F. , ZANELLA, John M.
IPC分类号： A61L27/36 , A61L27/40
CPC分类号： A61L27/365 , A61L27/3608 , A61L27/3847 , A61L27/40
摘要： A method for enhancing the binding of growth factors and/or cells to an allograft structure by applying an effective quantity of a coating material to the surface of the allograft structure, producing a thin coated allograft structure, administering to the thin coated allograft structure a growth factor, cells or a combination thereof, and implanting the thin coated allograft structure into a host bone.
摘要翻译：一种通过将有效量的涂层材料施用于同种异体移植物结构的表面来增强生长因子和/或细胞与同种异体移植物结构的结合的方法，产生薄的涂覆的同种异体移植物结构，向薄涂层的同种异体移植结构施用生长因子，细胞或其组合，以及将薄涂层的同种异体移植物结构植入宿主骨中。

3. 发明申请

WO2008127366A2 A DEVICE AND METHOD FOR TREATING OSTEOLYSIS USING A DRUG DEPOT TO DELIVER AN ANTI-INFLAMMATORY AGENT 审中-公开
标题翻译：一种使用药物给予抗炎药物治疗骨质疏松症的装置和方法
公开(公告)号：WO2008127366A2
公开(公告)日：2008-10-23
申请号：PCT/US2007/081448
申请日：2007-10-16
申请人： WARSAW ORTHOPEDIC, INC. , ZANELLA, John M.
发明人： ZANELLA, John M.
IPC分类号： A61L27/54
CPC分类号： A61L27/54 , A61K31/366 , A61K31/401 , A61L27/58 , A61L2300/402 , A61L2300/406 , A61L2300/41 , A61L2300/414 , A61L2300/602 , A61L2300/62 , A61L2430/02
摘要： The present invention relates to a device and method of treating an osteo-degenerative disease followed by an optional procedure using an osteoconductive material to accelerate healing of bone tissue damaged by the disease. The device for treating the bone degenerative disease comprises an in situ drug depot that time releases at least one anti-inflammatory agent. The method for treating an osteo-degenerative disease comprising: a) the combination of at least one anti-inflammatory agent with a flowable drug carrier, b) delivering the flowable drug carrier/anti-inflammatory mixture to a bone lesion, c) in situ curing of the mixture forming a rigid drug depot, d) wherein the drug depot bio-resorbs releasing the anti-inflammatory agent over time to treat a degenerative bone disease), and e) followed by an optional treatment using an osteoconductive material in combination with a growth factor.
摘要翻译：本发明涉及一种治疗骨退行性疾病的装置和方法，随后是使用骨传导材料的任选程序，以加速由该疾病损伤的骨组织的愈合。用于治疗骨退行性疾病的装置包括时间释放至少一种抗炎剂的原位药物贮库。用于治疗骨退行性疾病的方法，包括：a）至少一种抗炎剂与可流动药物载体的组合，b）将可流动的药物载体/抗炎混合物递送至骨损伤，c）原位固化形成刚性药物贮库的混合物，d）其中药物贮库生物吸收剂随时间释放抗炎剂以治疗退行性骨病），和e）然后使用骨传导材料与一个生长因子

4. 发明公开

EP2068919A2 METHODS OF TREATING TENDONITIS IN A SUBJECT BY USING AN ANTI-CYTOKINE AGENT 审中-公开
标题翻译：法肌腱炎的治疗通过使用抗细胞因子-BY
公开(公告)号：EP2068919A2
公开(公告)日：2009-06-17
申请号：EP07841952.0
申请日：2007-09-06
申请人： Warsaw Orthopedic, Inc.
发明人： ZANELLA, John M.
IPC分类号： A61K39/395
CPC分类号： C07K16/24 , A61K2039/505
摘要： A method for treating tendonitis and bursitis in a subject involves providing an effective amount of an anti-cytokine agent to a musculo-tendinious structure. Anti-cytokine agents, such as, TNF-α inhibitors, NF-B inhibitors, IL-1 inhibitors, IL-6 inhibitors, IL-8 inhibitors, IL-12 inhibitors, IL-15 inhibitors, IL-10, Interferon-gamma (IFN-gamma) act to prevent further inflammation initiated by cytokine factors. One embodiment includes, adding with the anti-cytokine agent one or more of an antibiotic or analgesic. Delivery of the anti-cytokine agent may be provided to the affected musculo-tendinious structure by injection, implantation, or a transdermal patch. These agents, individually or in combination directly address the underlying causes of tendonitis, bursitis and associated tendinopathies that result in inflammation and pain.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式