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    • 7. 发明申请
    • ORAL COMPOSITIONS AND METHOD FOR PRODUCING THEREOF
    • 口腔组合物及其生产方法
    • WO2012082103A1
    • 2012-06-21
    • PCT/US2010/060114
    • 2010-12-13
    • COLGATE-PALMOLIVE COMPANYGU, BenHASSAN, Mahmoud
    • GU, BenHASSAN, Mahmoud
    • A61Q11/00A61K8/92A61K8/73
    • A61K8/731A61K8/922A61Q11/00
    • Methods of preparing a dentifrice comprising polymer matrix film with menthol therein are disclosed. The methods comprise combining a polymer matrix film that comprises hydrophobic additives and is free of a low solubility flavorant such as menthol with a dentifrice base comprising a low solubility flavorant such as menthol and maintaining the combined polymer matrix film with the dentifrice base comprising low solubility flavorant for an amount of time sufficient for an amount of a low solubility flavorant to transfer from the dentifrice base comprising low solubility flavorant to the polymer matrix film and establish an equilibrium of menthol concentration between the polymer matrix film and the dentifrice base. Products comprising low solubility flavorant-free polymer matrix film in a dentifrice base comprising low solubility flavorant are also disclosed.
    • 公开了制备含有薄荷醇的聚合物基质膜的洁齿剂的方法。 所述方法包括组合包含疏水性添加剂的聚合物基质膜,并且不含低溶解度食用香料如薄荷醇,其中含有低分子量调味剂如薄荷醇的洁牙剂碱,并且将含有低溶解度食用香料的洁牙剂底物保持在组合的聚合物基质膜中 足以使一定量的低溶解度食用香料从包含低溶解度食用香料的洁牙剂基质转移到聚合物基质膜上,并建立聚合物基质膜和洁齿剂基质之间的薄荷醇浓度的平衡。 还公开了包含低溶解性食用香料的洁牙剂底物中含有低溶解度无味剂的聚合物基质膜的产品。