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1. 发明申请

WO2011063416A2 MICROFLUIDIC DEVICES FOR THE CAPTURE OF BIOLOGICAL SAMPLE COMPONENTS 审中-公开
标题翻译：用于捕获生物样品组分的微流体装置
公开(公告)号：WO2011063416A2
公开(公告)日：2011-05-26
申请号：PCT/US2010057894
申请日：2010-11-23
申请人： GEN HOSPITAL CORP , BARBER THOMAS A , SHAH AJAY , WALSH JOHN , TONER MEHMET , KAPUR RAVI
发明人： BARBER THOMAS A , SHAH AJAY , WALSH JOHN , TONER MEHMET , KAPUR RAVI
IPC分类号： G01N35/08 , G01N1/28 , G01N33/48 , G01N33/53 , G01N33/574
CPC分类号： G01N33/57492 , B01L3/502753 , B01L2300/0816 , B01L2400/0487 , B01L2400/086 , G01N15/1484 , G01N33/537 , G01N33/54306 , G01N33/56972
摘要： Methods and systems for selectively capturing analytes, such as cells, e.g., circulating tumor cells (CTCs), from fluid samples are disclosed. The methods include contacting the sample with an analyte binding moiety that selectively binds to the analytes; optionally separating first components of the sample including a majority of the analytes bound to the binding moieties from second components of the sample using size-based separation, e.g., in a microfluidic channel; adding to the first components of the sample a plurality of binding agents under conditions that enable a plurality of the binding agents to be linked to the analyte binding moieties to form multivalent tagging agents bound to the analyte; passing the first components of the sample past a surface to which is attached a plurality of capture agents that selectively bind to the binding agents; and capturing the analytes by providing conditions that enable the multivalent tagging agents bound to the analytes to bind to one or more of the capture agents.
摘要翻译：公开了用于从流体样品中选择性地捕获分析物例如细胞例如循环肿瘤细胞（CTC）的方法和系统。所述方法包括使样品与选择性结合分析物的分析物结合部分接触; 任选地使用基于尺寸的分离（例如在微流体通道中）分离样品的第一组分，所述第一组分包含与样品的第二组分结合的结合部分的大部分分析物; 在允许多个结合剂连接到分析物结合部分以形成与分析物结合的多价标签试剂的条件下，向样品的第一组分加入多种结合剂; 使样品的第一组分通过附着有选择性结合粘合剂的多个捕获剂的表面; 并通过提供使得能够与分析物结合的多价标签试剂与一种或多种捕获剂结合的条件来捕获分析物。

2. 发明申请

WO2009059112A2 MOTOR DRIVE MECHANISM FOR AN ELECTRONIC DEADBOLT LOCK 审中-公开
标题翻译：用于电子脱扣锁的电机驱动机构
公开(公告)号：WO2009059112A2
公开(公告)日：2009-05-07
申请号：PCT/US2008081964
申请日：2008-10-31
申请人： SCHLAGE LOCK CO , BOGDANOV VICTOR , LEVESQUE ALFRED SIMON , WALSH JOHN
发明人： BOGDANOV VICTOR , LEVESQUE ALFRED SIMON , WALSH JOHN
IPC分类号： E05B15/10 , E05B9/02 , E05B47/00
CPC分类号： E05B63/0017 , E05B47/0012 , E05B47/0692 , E05B2047/0016 , E05B2047/0023 , E05B2047/0026 , E05B2047/0031 , E05B2047/0086 , Y10T70/7062 , Y10T70/7113
摘要： An apparatus including a motor that has a rotatable output shaft extending outward from the motor and defining a rotational axis. The apparatus also includes a coupler that is coupled to the output shaft for rotation therewith, and a coil spring that is coupled to the coupler without external attachment means such that rotation of the coupler is transferred to the coil spring.
摘要翻译：一种包括马达的装置，其具有从马达向外延伸并且限定旋转轴线的可旋转输出轴。该装置还包括耦合到耦合到输出轴以与之一起旋转的耦合器，以及耦合到耦合器而没有外部附接装置的螺旋弹簧，使得耦合器的旋转传递到螺旋弹簧。

3. 发明申请

WO2012083150A3 METHODS FOR THE ISOLATION, ACCUMULATION CHARACTERIZATION AND/OR IDENTIFICATION OF MICROORGANISMS USING A FILTRATION AND SAMPLE TRANSFER DEVICE 审中-公开
标题翻译：用过滤和样品转移装置分离，积累表征和/或鉴定微生物的方法
公开(公告)号：WO2012083150A3
公开(公告)日：2012-08-02
申请号：PCT/US2011065449
申请日：2011-12-16
申请人： BIO MERIEUX INC , WALSH JOHN , HYMAN JONES , RONSICK CHRISTOPHER S
发明人： WALSH JOHN , HYMAN JONES , RONSICK CHRISTOPHER S
IPC分类号： B01L3/00
CPC分类号： B01L3/50255 , B01L3/561 , B01L2300/0681
摘要： The present invention is directed to methods, devises and kits for separating, accumulating, characterizing and/or identifying microorganisms known to be present or that may be present in a test sample. The method of the invention comprises optional lysing non-microorganism cells and/or particulates that may be present in a test sample, followed by a subsequent filtration step for isolation and/or accumulation of microorganisms. In one embodiment, a filtration and sample transfer device is used for isolation and/or accumulation of microorganisms by filtration. Once the microorganisms have been filtered for isolation and/or accumulation microorganisms, the isolated and/or accumulated microorganisms can be analyzing to acquire measurements for the characterization and/or identification of said microorganisms.
摘要翻译：本发明涉及用于分离，积累，表征和/或鉴定已知存在或可能存在于测试样品中的微生物的方法，设备和试剂盒。本发明的方法包括任选的裂解非微生物细胞和/或可能存在于测试样品中的颗粒，接着是随后的用于分离和/或积聚微生物的过滤步骤。在一个实施方案中，过滤和样品转移装置用于通过过滤分离和/或积累微生物。一旦微生物已被过滤以分离和/或积累微生物，就可以分析分离的和/或积累的微生物以获得用于所述微生物的表征和/或鉴定的测量。

4. 发明申请

WO2007008694A2 ELECTRONIC LOCK ACTUATOR WITH HELICAL DRIVE MEMBER 审中-公开
标题翻译：带螺旋驱动部件的电子锁定执行器
公开(公告)号：WO2007008694A2
公开(公告)日：2007-01-18
申请号：PCT/US2006026572
申请日：2006-07-07
申请人： HARROW PRODUCTS LLC , WALSH JOHN
发明人： WALSH JOHN
IPC分类号： E05B47/06
CPC分类号： E05B47/0661 , E05B47/0012 , E05B47/068 , E05B2047/0016 , E05B2047/0023 , E05B2047/0031 , Y10T70/5416 , Y10T70/5827 , Y10T70/7062 , Y10T70/7068 , Y10T70/7102 , Y10T70/713
摘要： An actuator assembly is for a lock including a handle, a latch, a retractor for retracting the latch when the handle rotates, and a lock member displaceable between locked and unlocked positions, which either releasably couples the handle with the retractor or releasably prevents handle rotation. The actuator includes a motor having a shaft rotatable about an axis and a coupler spring disposed about the axis and having a first end coupled with the lock member and a second end. A drive member is coupled or integrally formed with the motor shaft and has a helical drive surface threadably engaged with the coupler spring second end, such that rotation of the shaft displaces the coupler spring along the axis to move the lock member between the locked and unlocked positions. Preferably, the drive member includes a spring coupled with the motor shaft and threadably engaged with the coupler spring.
摘要翻译：致动器组件用于包括手柄，闩锁，当手柄旋转时用于收回闩锁的收缩器的锁定器，以及可在锁定位置和解锁位置之间移动的锁定构件，锁定构件可释放地将手柄与牵开器联接或可释放地防止手柄旋转。致动器包括具有可绕轴线旋转的轴的马达以及围绕轴线设置的联接器弹簧，联接器弹簧具有与锁定构件联接的第一端和第二端。驱动构件与马达轴联接或一体形成并且具有与联接器弹簧第二端螺纹接合的螺旋驱动表面，使得轴的旋转使联接器弹簧沿轴线移动，以将锁定构件在锁定和解锁之间移动位置。优选地，驱动构件包括与马达轴联接并与联接器弹簧螺纹接合的弹簧。

5. 发明授权

US744887A Sectional plastic step. 失效
标题翻译：部分塑料步骤。
公开(公告)号：US744887A
公开(公告)日：1903-11-24
申请号：US1903153620
申请日：1903-04-21
申请人： WALSH JOHN
发明人： WALSH JOHN
CPC分类号： E04F11/022

6. 发明申请

WO2010077304A3 METHODS FOR THE CHARACTERIZATION OF MICROORGANISMS ON SOLID OR SEMI-SOLID MEDIA 审中-公开
标题翻译：用于表征固体或半固体培养基上微生物的方法
公开(公告)号：WO2010077304A3
公开(公告)日：2010-09-30
申请号：PCT/US2009006545
申请日：2009-12-15
申请人： BIO MERIEUX INC , WALSH JOHN , HYMAN JONES , THORPE THURMAN
发明人： WALSH JOHN , HYMAN JONES , THORPE THURMAN
IPC分类号： G01N33/50
CPC分类号： C12Q1/04
摘要： The present invention relates to methods and systems for scanning, detecting, and monitoring microorganisms on solid or semi-solid media using intrinsic fluorescence (IF) measurements. The methods are further directed to detection, characterization and/or identification of microorganisms on a solid or semi-solid media using intrinsic fluorescence (IF) measurements that are characteristic of said microorganisms.
摘要翻译：本发明涉及使用固有荧光（IF）测量在固体或半固体培养基上扫描，检测和监测微生物的方法和系统。所述方法进一步涉及使用固有荧光（IF）测量（其是所述微生物的特征）在固体或半固体培养基上检测，表征和/或鉴定微生物。

7. 发明申请

WO2008063390A3 WAGERING GAME WITH 3D GAMING ENVIRONMENT USING DYNAMIC CAMERA 审中-公开
标题翻译：使用动态相机3D游戏环游戏
公开(公告)号：WO2008063390A3
公开(公告)日：2008-07-17
申请号：PCT/US2007023259
申请日：2007-11-05
申请人： WMS GAMING INC , JOHNSON KEVIN , WALSH JOHN
发明人： JOHNSON KEVIN , WALSH JOHN
IPC分类号： A63F9/24
CPC分类号： G07F17/32
摘要： A gaming system for playing a wagering game includes an input device for receiving a wager to play a wagering game, a display, and a controller. The controller is configured to display a three-dimensional view of at least a portion of a gaming environment and one or more movable visual elements disposed within the gaming environment. The controller is further configured to dynamically retain within the field of view a center point of a selected set of the movable visual elements.
摘要翻译：用于玩投注游戏的游戏系统包括用于接收下注以玩下注游戏的输入装置，显示器和控制器。控制器被配置为显示游戏环境的至少一部分和设置在游戏环境内的一个或多个可移动视觉元素的三维视图。控制器还被配置为在视场内动态地保持所选择的一组可移动视觉元件的中心点。

8. 发明申请

WO2007021560A3 THREE-DIMENSIONAL GAMING SYSTEM ENVIRONMENTS 审中-公开
标题翻译：三维游戏系统环境
公开(公告)号：WO2007021560A3
公开(公告)日：2007-04-26
申请号：PCT/US2006030191
申请日：2006-08-03
申请人： WMS GAMING INC , WALSH JOHN , PACEY LARRY , HORNIK JEREMY
发明人： WALSH JOHN , PACEY LARRY , HORNIK JEREMY
IPC分类号： A63F9/24
CPC分类号： G07F17/3202 , G07F17/3211
摘要： Methods and apparatus affecting the interaction between events, objects, and three-dimensional wagering game environment are described herein.
摘要翻译：本文描述了影响事件，对象和三维投注游戏环境之间的相互作用的方法和装置。

9. 发明专利

CH399083A Organe de fixation destiné à être appliqué à un matériau en feuilles 未知
公开(公告)号：CH399083A
公开(公告)日：1966-03-31
申请号：CH245663
申请日：1963-02-26
申请人： WALSH JOHN & CO INSERTS LTD
发明人： WALSH JOHN
IPC分类号： F16B37/06

10. 发明专利

CA115907A SAFETY DEVICE FOR ELEVATORS 未知
公开(公告)号：CA115907A
公开(公告)日：1908-12-29
申请号：CA115907D
申请日：1908-12-03
申请人： WALSH JOHN
发明人： WALSH JOHN

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