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1. 发明授权

US08253937B2 Optical evaluation method by means of laser pulses and corresponding apparatus 有权
标题翻译：光学评估方法采用激光脉冲和相应装置
公开(公告)号：US08253937B2
公开(公告)日：2012-08-28
申请号：US12626057
申请日：2009-11-25
申请人： Vishnu Vardhan Krishnamachari , William C. Hay , Volker Seyfried , Bernd Widzgowski
发明人： Vishnu Vardhan Krishnamachari , William C. Hay , Volker Seyfried , Bernd Widzgowski
IPC分类号： G01J3/44
CPC分类号： G01N21/63
摘要： An optical evaluation method and an apparatus for performing said method are described. First laser pulses of a first type and second laser pulses of a second type that differs from the first type are sent onto a sample to be examined. The sample is hit with first incident light from the two laser pulses in at least one manner of simultaneously, within a very short time lag between the two laser pulses, and a time-correlated manner of the two laser pulses, thereby generating a first optical signal, and hit with second incident light from the two laser pulses, thereby generating a second optical signal. The generated first and second optical signals are detected with at least one detector; and an electronic difference between the first and second optical signals is generated.
摘要翻译：描述了用于执行所述方法的光学评估方法和装置。第一类型的第一激光脉冲和第二类型的与第一类型不同的第二激光脉冲被发送到要检查的样品上。在两个激光脉冲之间的非常短的时间间隔内，以两个激光脉冲的时间相关方式，以至少一种方式同时来自两个激光脉冲的第一入射光和第二激光脉冲的时间相关方式，信号，并用来自两个激光脉冲的第二入射光击中，从而产生第二光信号。产生的第一和第二光信号用至少一个检测器检测; 并且产生第一和第二光信号之间的电子差异。

2. 发明申请

US20100134793A1 OPTICAL EVALUATION METHOD BY MEANS OF LASER PULSES AND CORRESPONDING APPARATUS 有权
标题翻译：激光脉冲和相关装置的光学评估方法
公开(公告)号：US20100134793A1
公开(公告)日：2010-06-03
申请号：US12626057
申请日：2009-11-25
申请人： Vishnu Vardhan Krishnamachari , William C. Hay , Volker Seyfried , Bernd Widzgowski
发明人： Vishnu Vardhan Krishnamachari , William C. Hay , Volker Seyfried , Bernd Widzgowski
IPC分类号： G01J3/30 , G01J3/44
CPC分类号： G01N21/63
摘要： An optical evaluation method and an apparatus for performing said method are described. First laser pulses of a first type and second laser pulses of a second type that differs from the first type are sent onto a sample to be examined. The sample is hit with first incident light from the two laser pulses in at least one manner of simultaneously, within a very short time lag between the two laser pulses, and a time-correlated manner of the two laser pulses, thereby generating a first optical signal, and hit with second incident light from the two laser pulses, thereby generating a second optical signal. The generated first and second optical signals are detected with at least one detector; and an electronic difference between the first and second optical signals is generated.
摘要翻译：描述了用于执行所述方法的光学评估方法和装置。第一类型的第一激光脉冲和第二类型的与第一类型不同的第二激光脉冲被发送到要检查的样品上。在两个激光脉冲之间的非常短的时间间隔内，以两个激光脉冲的时间相关方式，以至少一种方式同时来自两个激光脉冲的第一入射光和第二激光脉冲的时间相关方式，信号，并用来自两个激光脉冲的第二入射光击中，从而产生第二光信号。产生的第一和第二光信号用至少一个检测器检测; 并且产生第一和第二光信号之间的电子差异。

3. 发明授权

US08610996B2 Tunable multiple laser pulse scanning microscope and method of operating the same 有权
标题翻译：可调多重激光脉冲扫描显微镜及其操作方法
公开(公告)号：US08610996B2
公开(公告)日：2013-12-17
申请号：US12775395
申请日：2010-05-06
申请人： Vishnu Vardhan Krishnamachari , William C. Hay
发明人： Vishnu Vardhan Krishnamachari , William C. Hay
IPC分类号： G02F1/11
CPC分类号： G02B21/0032 , G02B21/0076
摘要： A tunable multiple laser pulse scanning microscope and a method of operating the same is described, applying two pulsed laser beams with distinct wavelengths incident on a scanning spot of a sample to be imaged simultaneously or at a specific time delay. The microscope comprises at least two pulsed laser light sources emitting laser light of distinct wavelengths, an acousto-optic tunable filter (AOTF) for tuning at least one of the laser pulses, a delay stage provided upstream of the AOTF, and an actuator for moving delay stage depending on the time delay. As a result, the wavelength of at least one type of pulses is tuned, and the delay between at least two pulses of distinct wavelengths is adjusted.
摘要翻译：描述了可调多激光脉冲扫描显微镜及其操作方法，应用两个具有不同波长的脉冲激光束入射到要同时成像的样品的扫描点或者以特定的时间延迟。显微镜包括至少两个发射不同波长的激光的脉冲激光光源，用于调谐至少一个激光脉冲的声光可调谐滤波器（AOTF），设置在AOTF上游的延迟级，以及用于移动的致动器延迟时间取决于时间延迟。结果，调谐至少一种类型的脉冲的波长，并且调整不同波长的至少两个脉冲之间的延迟。

4. 发明申请

US20110273768A1 TUNABLE MULTIPLE LASER PULSE SCANNING MICROSCOPE AND METHOD OF OPERATING THE SAME 有权
标题翻译：多功能激光脉冲扫描显微镜及其操作方法
公开(公告)号：US20110273768A1
公开(公告)日：2011-11-10
申请号：US12775395
申请日：2010-05-06
申请人： Vishnu Vardhan Krishnamachari , William C. Hay
发明人： Vishnu Vardhan Krishnamachari , William C. Hay
IPC分类号： G02B21/06 , G02F1/39
CPC分类号： G02B21/0032 , G02B21/0076
摘要： A tunable multiple laser pulse scanning microscope and a method of operating the same is described, applying two pulsed laser beams with distinct wavelengths incident on a scanning spot of a sample to be imaged simultaneously or at a specific time delay. The microscope comprises at least two pulsed laser light sources emitting laser light of distinct wavelengths, an acousto-optic tunable filter (AOTF) for tuning at least one of the laser pulses, a delay stage provided upstream of the AOTF, and an actuator for moving delay stage depending on the time delay. As a result, the wavelength of at least one type of pulses is tuned, and the delay between at least two pulses of distinct wavelengths is adjusted.
摘要翻译：描述了可调多激光脉冲扫描显微镜及其操作方法，应用两个具有不同波长的脉冲激光束入射到要同时成像的样品的扫描点或者以特定的时间延迟。显微镜包括至少两个发射不同波长的激光的脉冲激光光源，用于调谐至少一个激光脉冲的声光可调谐滤波器（AOTF），设置在AOTF上游的延迟级，以及用于移动的致动器延迟时间取决于时间延迟。结果，调谐至少一种类型的脉冲的波长，并且调整不同波长的至少两个脉冲之间的延迟。

5. 发明授权

US08488118B2 Apparatus and method for multi-modal imaging in nonlinear raman microscopy 有权
标题翻译：非线性拉曼显微镜多模态成像装置及方法
公开(公告)号：US08488118B2
公开(公告)日：2013-07-16
申请号：US13048353
申请日：2011-03-15
申请人： Vishnu Vardhan Krishnamachari
发明人： Vishnu Vardhan Krishnamachari
IPC分类号： G01J3/44
CPC分类号： G01J3/10 , G01J3/02 , G01J3/0224 , G01J3/36 , G01J3/44 , G01N21/65 , G01N2021/653 , G01N2021/655
摘要： An apparatus for the microscopic examination of an object has an illumination system which generates a first illumination light beam and a second illumination light beam. A first polarization filter (28) circularly polarizes the first illumination light beam. A second polarization filter (32) linearly polarizes the second illumination light beam. A modulator (34) allows a modulation of the polarized second illumination light beam. An excitation optical system directs the two illumination light beams onto an object. A detection optical system directs detection light beams emanating from the object onto at least two detector units, a first detector unit detecting a first nonlinear Raman effect and a second detector unit detecting a second nonlinear Raman effect.
摘要翻译：用于物体的显微镜检查的装置具有产生第一照明光束和第二照明光束的照明系统。第一偏振滤光器（28）使第一照明光束圆偏振。第二偏振滤光器（32）使第二照明光束线性偏振。调制器（34）允许调制偏振的第二照明光束。激发光学系统将两个照明光束引导到物体上。检测光学系统将从物体发出的检测光束引导到至少两个检测器单元，检测第一非线性拉曼效应的第一检测器单元和检测第二非线性拉曼效应的第二检测器单元。

6. 发明申请

US20110222054A1 Apparatus and Method for Multi-Modal Imaging in Nonlinear Raman Microscopy 有权
标题翻译：非线性拉曼显微镜多模态成像装置与方法
公开(公告)号：US20110222054A1
公开(公告)日：2011-09-15
申请号：US13048353
申请日：2011-03-15
申请人： Vishnu Vardhan Krishnamachari
发明人： Vishnu Vardhan Krishnamachari
IPC分类号： G01J3/44
CPC分类号： G01J3/10 , G01J3/02 , G01J3/0224 , G01J3/36 , G01J3/44 , G01N21/65 , G01N2021/653 , G01N2021/655
摘要： An apparatus for the microscopic examination of an object has an illumination system which generates a first illumination light beam and a second illumination light beam. A first polarization filter (28) circularly polarizes the first illumination light beam. A second polarization filter (32) linearly polarizes the second illumination light beam. A modulator (34) allows a modulation of the polarized second illumination light beam. An excitation optical system directs the two illumination light beams onto an object. A detection optical system directs detection light beams emanating from the object onto at least two detector units, a first detector unit detecting a first nonlinear Raman effect and a second detector unit detecting a second nonlinear Raman effect.
摘要翻译：用于物体的显微镜检查的装置具有产生第一照明光束和第二照明光束的照明系统。第一偏振滤光器（28）使第一照明光束圆偏振。第二偏振滤光器（32）使第二照明光束线性偏振。调制器（34）允许调制偏振的第二照明光束。激发光学系统将两个照明光束引导到物体上。检测光学系统将从物体发出的检测光束引导到至少两个检测器单元，检测第一非线性拉曼效应的第一检测器单元和检测第二非线性拉曼效应的第二检测器单元。

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