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    • 1. 发明授权
    • Reagent pouch for use in a modular automated diagnostic apparatus
    • 用于模块化自动诊断仪器的试剂袋
    • US06178832B2
    • 2001-01-30
    • US09350054
    • 1999-07-08
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • G01N100
    • G01N35/1002G01N35/00712G01N35/1095
    • A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement so that a biological sample does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of calibration and cleaning fluids and the aspiration of fluids into the analysis apparatus from different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensor chamber are structured to mechanically stack and interlock and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
    • 一种模块化自动诊断分析仪,具有用于抽样抽吸的流体输入模块,用于选择流体的阀模块和用于流体运动的泵模块,使得生物样品不与阀系统接触,通过该阀系统将校准物和空气引入到 流体路径 流体进入模块包围一个抽吸管,该抽吸管与分析机构底盘可旋转地并可滑动地接合,以移动到不同的位置,用于引入校准和清洁流体,以及从不同类型的样品容器将流体抽吸到分析装置中。 擦拭密封件从抽吸管的外表面去除吸入流体的残留物,并将残留物吸入分析装置中进行处置。 安装在传感器室中的传感器模块被构造成机械地堆叠和互锁,并且每个传感器模块包括流体密封的通道和传感器元件。 高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。 独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物,其中每个袋壁包括多层材料,其中至少一层是薄的柔性玻璃材料。 壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈,使得试剂袋中没有气泡被捕获。
    • 2. 发明授权
    • Fluid entry mechanism for a modular automated diagnostic apparatus
    • 模块化自动诊断仪的流体输入机构
    • US06418800B1
    • 2002-07-16
    • US09663719
    • 2000-09-15
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • G01N100
    • G01N35/1002G01N35/00712G01N35/1095
    • A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement, so that a biological sample does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of calibration and cleaning fluids and the aspiration of fluids into the analysis apparatus from different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensor chamber are structured to mechanically stack and interlock and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
    • 一种模块化自动诊断分析仪,具有用于样品抽吸的流体入口模块,用于选择流体的阀模块和用于流体运动的泵模块,使得生物样品不与阀系统接触,通过该系统将校准物和空气引入到 流体路径。 流体进入模块包围一个抽吸管,该抽吸管与分析机构底盘可旋转地并可滑动地接合,以移动到不同的位置,用于引入校准和清洁流体,以及从不同类型的样品容器将流体抽吸到分析装置中。 擦拭密封件从抽吸管的外表面去除吸入流体的残留物,并将残留物吸入分析装置中进行处置。 安装在传感器室中的传感器模块被构造成机械地堆叠和互锁,并且每个传感器模块包括流体密封的通道和传感器元件。 高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。 独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物,其中每个袋壁包括多层材料,其中至少一层是薄的柔性玻璃材料。 壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈,使得试剂袋中没有气泡被捕获。
    • 3. 发明授权
    • Modular film sensors with record memory for a modular automated diagnostic apparatus
    • 具有记录存储器的模块化电影传感器,用于模块化自动诊断设备
    • US07127957B2
    • 2006-10-31
    • US11053277
    • 2005-02-08
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • G01N1/00
    • G01N35/1002G01N35/00712G01N35/1095G01N2035/00683
    • A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement so that a biological samples does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of fluids into the analysis apparatus from different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensors chamber are structured to mechanically stack and interlock and include film sensors with use life record memories and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
    • 一种模块化自动诊断分析仪,具有用于抽样抽吸的流体进入模块,用于选择流体的阀模块和用于流体运动的泵模块,使得生物样品不与阀系统接触,通过该系统将校准物和空气引入到 流体路径 流体进入模块包围一个抽吸管,该抽吸管与分析机构底盘可旋转地并可滑动地接合,以移动到不同的位置,以便从不同类型的样品容器将流体引入分析装置。 擦拭密封件从抽吸管的外表面去除吸入流体的残留物,并将残留物吸入分析装置中进行处置。 安装在传感器室中的传感器模块被构造成机械地堆叠和互锁并且包括具有使用寿命记录存储器的膜传感器,并且每个传感器模块包括流体密封的通道和传感器元件。 高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。 独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物,其中每个袋壁包括多层材料,其中至少一层是薄的柔性玻璃材料。 壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈,使得试剂袋中没有气泡被捕获。
    • 4. 发明授权
    • Modular automated diagnostic analysis apparatus with a self cleaning
sample input port, an improved fluid selection port, and an improved
reagent pack
    • 具有自清洁样品输入端口,改进的流体选择端口和改进的试剂盒的模块化自动诊断分析装置
    • US5983734A
    • 1999-11-16
    • US118683
    • 1998-06-30
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • G01N1/00G01N35/00G01N35/10
    • G01N35/1002G01N35/00712G01N35/1095
    • A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement so that a biological sample does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of calibration and cleaning fluids and the aspiration of fluids into the analysis apparatus from a different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensor chamber are structured to mechanically stack and interlock and each sensor module includes a fluid tight sealed passage and a sensor element. An fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pack contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
    • 一种模块化自动诊断分析仪,具有用于抽样抽吸的流体输入模块,用于选择流体的阀模块和用于流体运动的泵模块,使得生物样品不与阀系统接触,通过该阀系统将校准物和空气引入到 流体路径 流体进入模块包围一个抽吸管,该抽吸管与分析机构底盘可旋转地并可滑动地接合,以移动到不同的位置,用于引入校准和清洁流体,以及从不同类型的样品容器将流体抽吸到分析装置中。 擦拭密封件从抽吸管的外表面去除吸入流体的残留物,并将残留物吸入分析装置中进行处置。 安装在传感器室中的传感器模块被构造成机械地堆叠和互锁,并且每个传感器模块包括流体密封的通道和传感器元件。 高度抛光的陶瓷材料的流体选择阀允许阀芯通道选择性地连接到流体源。 独立的试剂盒包含在试剂袋中包括计量校准物的校准物,其中每个袋壁包括多层材料,其中至少一层是薄的柔性玻璃材料。 壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈,使得试剂袋中没有气泡被捕获。
    • 5. 发明授权
    • Fluid selection valve for a modular automated diagnostic apparatus
    • 用于模块化自动诊断仪的流体选择阀
    • US06293162B1
    • 2001-09-25
    • US09350247
    • 1999-07-08
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • G01N100
    • G01N35/1002G01N35/00712G01N35/1095
    • A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement, so that a biological sample does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of calibration and cleaning fluids and the aspiration of fluids into the analysis apparatus from different tpes of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensor chamber are structured to mechanically stack and interlock and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
    • 一种模块化自动诊断分析仪,具有用于样品抽吸的流体入口模块,用于选择流体的阀模块和用于流体运动的泵模块,使得生物样品不与阀系统接触,通过该系统将校准物和空气引入到 流体路径。 流体进入模块将抽吸管与分析机构底座可旋转地并可滑动地接合以移动到不同的位置,以引入校准和清洁流体,以及从不同的样品容器的抽吸将流体抽入分析装置。 擦拭密封件从抽吸管的外表面去除吸入流体的残留物,并将残留物吸入分析装置中进行处置。 安装在传感器室中的传感器模块被构造成机械地堆叠和互锁,并且每个传感器模块包括流体密封的通道和传感器元件。 高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。 独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物,其中每个袋壁包括多层材料,其中至少一层是薄的柔性玻璃材料。 壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈,使得试剂袋中没有气泡被捕获。
    • 6. 发明授权
    • Modular sensor system for a modular automated diagnostic apparatus
    • 用于模块化自动诊断仪的模块化传感器系统
    • US06289751B1
    • 2001-09-18
    • US09350055
    • 1999-07-08
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • G01N100
    • G01N35/1002G01N35/00712G01N35/1095
    • A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement. so that a biological sample does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of calibration and cleaning fluids and the aspiration of fluids into the analysis apparatus from different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensor chamber are structured to mechanically stack and interlock and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
    • 一种模块化自动诊断分析仪,具有用于样品抽吸的流体进入模块,用于选择流体的阀模块和用于流体运动的泵模块。 使得生物样品不与阀系统接触,通过该系统将校准物和空气引入流体路径。 流体进入模块包围一个抽吸管,该抽吸管与分析机构底盘可旋转地并可滑动地接合,以移动到不同的位置,用于引入校准和清洁流体,以及从不同类型的样品容器将流体抽吸到分析装置中。 擦拭密封件从抽吸管的外表面去除吸入流体的残留物,并将残留物吸入分析装置中进行处置。 安装在传感器室中的传感器模块被构造成机械地堆叠和互锁,并且每个传感器模块包括流体密封的通道和传感器元件。 高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。 独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物,其中每个袋壁包括多层材料,其中至少一层是薄的柔性玻璃材料。 壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈,使得试剂袋中没有气泡被捕获。
    • 7. 发明申请
    • Modular film sensors with record memory for a modular automated diagnostic apparatus
    • 具有记录存储器的模块化电影传感器,用于模块化自动诊断设备
    • US20050145020A1
    • 2005-07-07
    • US11053277
    • 2005-02-08
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • G01N1/00G01N35/00G01N35/10G01N27/416G01N33/487
    • G01N35/1002G01N35/00712G01N35/1095G01N2035/00683
    • A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement so that a biological samples does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of fluids into the analysis apparatus from different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensors chamber are structured to mechanically stack and interlock and include film sensors with use life record memories and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
    • 一种模块化自动诊断分析仪,具有用于抽样抽吸的流体进入模块,用于选择流体的阀模块和用于流体运动的泵模块,使得生物样品不与阀系统接触,通过该系统将校准物和空气引入到 流体路径 流体进入模块包围一个抽吸管,该抽吸管与分析机构底盘可旋转地并可滑动地接合,以移动到不同的位置,以便从不同类型的样品容器将流体引入分析装置。 擦拭密封件从抽吸管的外表面去除吸入流体的残留物,并将残留物吸入分析装置中进行处置。 安装在传感器室中的传感器模块被构造成机械地堆叠和互锁并且包括具有使用寿命记录存储器的膜传感器,并且每个传感器模块包括流体密封的通道和传感器元件。 高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。 独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物,其中每个袋壁包括多层材料,其中至少一层是薄的柔性玻璃材料。 壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈,使得试剂袋中没有气泡被捕获。
    • 8. 发明授权
    • Modular film sensors with record memory for modular automated diagnostic apparatus
    • 具有记录存储器的模块化电影传感器,用于模块化自动诊断设备
    • US06886421B2
    • 2005-05-03
    • US10045464
    • 2001-11-08
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • Vijay MathurTyler CoteRonald JonesJane SunSteve RettewChen YiTony MaoWill WhelanKen GalanoRichard Dussault
    • G01N1/00G01N35/00G01N35/10
    • G01N35/1002G01N35/00712G01N35/1095G01N2035/00683
    • A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement so that a biological sample does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of fluids into the analysis apparatus from different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensor chamber are structured to mechanically stack and interlock and include film sensors with use life record memories and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
    • 一种模块化自动诊断分析仪,具有用于抽样抽吸的流体输入模块,用于选择流体的阀模块和用于流体运动的泵模块,使得生物样品不与阀系统接触,通过该系统将校准物和空气引入到 流体路径 流体进入模块包围一个抽吸管,该抽吸管与分析机构底盘可旋转地并可滑动地接合,以移动到不同的位置,以便从不同类型的样品容器将流体引入分析装置。 擦拭密封件从抽吸管的外表面去除吸入流体的残留物,并将残留物吸入分析装置中进行处置。 安装在传感器室中的传感器模块被构造成机械地堆叠和互锁并且包括使用寿命记录存储器的膜传感器,并且每个传感器模块包括流体密封的通道和传感器元件。 高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。 独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物,其中每个袋壁包括多层材料,其中至少一层是薄的柔性玻璃材料。 壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈,使得试剂袋中没有气泡被捕获。