专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

EP2059587B1 LACCASES FOR PULP BIO-BLEACHING 有权
标题翻译：漆酶对生物漂白纸浆
公开(公告)号：EP2059587B1
公开(公告)日：2012-01-04
申请号：EP07837576.3
申请日：2007-08-31
申请人： Verenium Corporation , BASF SE
发明人： KEROVUO, Janne Samuli , HAREMZA, Sylke , KOCH, Oliver , HABICHER, Tilo , ROBERTSON, Dan , DESANTIS, Grace , MCCANN, Ryan , LUGINBUHL, Peter
IPC分类号： C12N9/02 , C12N1/20 , C12N15/00 , C12Q1/00 , C12Q1/34 , C12Q1/68 , C12P21/06 , C12P21/04 , A61K38/44 , C07H21/04 , C07K1/00
CPC分类号： C12N9/0061 , C12N15/09 , C12P5/00 , C12P7/00 , C12P19/00 , C12Y110/03002 , D21C5/005 , D21C9/005 , D21C9/1063
摘要： Provided herein are isolated laccase enzymes and nucleic acids encoding them. Also provided are mediators for laccase reactions. Also provided herein are methods for using laccases to oxidize lignins and other phenolic and aromatic compounds, such as for bio-bleaching and decolorization of wood pulp under high temperature and pH conditions to facilitate a substantial reduction in use of bleaching chemicals, as well as for treatment of fibers.

2. 发明公开

EP2059587A2 LACCASES FOR PULP BIO-BLEACHING 有权
标题翻译：漆酶对生物漂白纸浆
公开(公告)号：EP2059587A2
公开(公告)日：2009-05-20
申请号：EP07837576.3
申请日：2007-08-31
申请人： Verenium Corporation , BASF SE
发明人： KEROVUO, Janne Samuli , HAREMZA, Sylke , KOCH, Oliver , HABICHER, Tilo , ROBERTSON, Dan , DESANTIS, Grace , MCCANN, Ryan , LUGINBUHL, Peter
IPC分类号： C12N9/02 , C12N1/20 , C12N15/00 , C12Q1/00 , C12Q1/34 , C12Q1/68 , C12P21/06 , C12P21/04 , A61K38/44 , C07H21/04 , C07K1/00 , C07K16/00
CPC分类号： C12N9/0061 , C12N15/09 , C12P5/00 , C12P7/00 , C12P19/00 , C12Y110/03002 , D21C5/005 , D21C9/005 , D21C9/1063
摘要： Provided herein are isolated laccase enzymes and nucleic acids encoding them. Also provided are mediators for laccase reactions. Also provided herein are methods for using laccases to oxidize lignins and other phenolic and aromatic compounds, such as for bio-bleaching and decolorization of wood pulp under high temperature and pH conditions to facilitate a substantial reduction in use of bleaching chemicals, as well as for treatment of fibers.

3. 发明申请

WO2008143679A2 NUCLEIC ACIDS AND PROTEINS AND METHODS FOR MAKING AND USING THEM 审中-公开
标题翻译：核酸和蛋白质及其制备和使用方法
公开(公告)号：WO2008143679A2
公开(公告)日：2008-11-27
申请号：PCT/US2007/070284
申请日：2007-06-01
申请人： VERENIUM CORPORATION , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , CALIFORNIA INSTITUTE OF TECHNOLOGY , CHANG, Cathy , MATHUR, Eric, J. , CAYOUETTE, Michelle , ROBERTSON, Dan, E. , HUGENHOLTZ, Philip , WARNECKE, Falk , LEADBETTER, Jared , IVANOVA, Natalia , LUGINBUHL, Peter , HUTCHISON, Don
发明人： CHANG, Cathy , MATHUR, Eric, J. , CAYOUETTE, Michelle , ROBERTSON, Dan, E. , HUGENHOLTZ, Philip , WARNECKE, Falk , LEADBETTER, Jared , IVANOVA, Natalia , LUGINBUHL, Peter , HUTCHISON, Don
IPC分类号： C12N9/24
CPC分类号： C12Y302/01015 , C12N9/2437 , C12Y302/01004 , C12Y302/01006 , C12Y302/01039 , C12Y302/01067 , C12Y302/01082
摘要： The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs. Polypeptides of the invention can be used in food processing, brewing, bath additives, alcohol production, peptide synthesis, enantioselectivity, hide preparation in the leather industry, waste management and animal degradation, silver recovery in the photographic industry, medical treatment, silk degumming, biofilm degradation, biomass conversion to a biofuel (e.g., a bioethanol, biomethanol, biopropanol or biobutanol, a biodiesel, etc.), biodefense, antimicrobial agents and disinfectants, personal care and cosmetics, biotech reagents, in corn wet milling and pharmaceuticals such as digestive aids and anti-inflammatory (anti-phlogistic) agents.
摘要翻译：本发明提供多肽，包括酶，结构蛋白和结合蛋白，编码这些多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。本发明的多肽，包括酶和抗体以及核酸可用于工业，实验，食品和饲料加工，营养和药物应用中，例如用于食品和饲料添加剂，着色剂，中性药物，化妆品和药物需求。本发明的多肽可用于食品加工，酿造，浴添加剂，酒精生产，肽合成，对映选择性，皮革行业中的皮革制备，废物管理和动物降解，摄影工业中的银回收，医疗，丝绸脱胶，生物膜降解，生物燃料转化为生物燃料（例如生物乙醇，生物甲醇，生物丙醇或生物丁醇，生物柴油等），生物防治剂，抗微生物剂和消毒剂，个人护理和化妆品，生物技术试剂，玉米湿法研磨和药物如消化助剂和抗炎（抗炎）药剂。

4. 发明申请

WO2007103989A2 ALDOLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 审中-公开
标题翻译： ALDOLASES，编码它们的核酸以及制备和使用它们的方法
公开(公告)号：WO2007103989A2
公开(公告)日：2007-09-13
申请号：PCT/US2007/063515
申请日：2007-03-07
申请人： VERENIUM CORPORATION , BURKE, Ellen , HICKS, Paula, M. , LUGINBUHL, Peter , RICHARDSON, Toby , WEINER, David, P. , ZHAO, Lishan
发明人： BURKE, Ellen , HICKS, Paula, M. , LUGINBUHL, Peter , RICHARDSON, Toby , WEINER, David, P. , ZHAO, Lishan
IPC分类号： C12N9/10
CPC分类号： C12N9/88 , A01K2217/05 , A61K38/00 , C07K2317/92 , C12N9/1022 , C12N15/8243 , C12P17/10 , C12Y401/03016 , C12Y401/03017 , Y02E50/16 , Y02E50/17

5. 发明申请

WO2009088753A1 ISOMERASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 审中-公开
标题翻译：异构体，编码它们的核酸及其制备和使用它们的方法
公开(公告)号：WO2009088753A1
公开(公告)日：2009-07-16
申请号：PCT/US2008/088066
申请日：2008-12-22
申请人： VERENIUM CORPORATION , WEINER, David , BURKE, Ellen , LUGINBUHL, Peter , BUENO, Analia , CUENCA, Joslin , DE SOUZA, Mervyn, L. , KOLLMANN, Sherry
发明人： WEINER, David , BURKE, Ellen , LUGINBUHL, Peter , BUENO, Analia , CUENCA, Joslin , DE SOUZA, Mervyn, L. , KOLLMANN, Sherry
IPC分类号： C12Q1/533 , C12N9/90 , C12N15/61 , A61K38/52 , C07K16/40
CPC分类号： C12N9/90 , A01K67/0275 , A01K2217/05 , A01K2227/10 , A23G3/366 , A23G4/123 , A23G4/14 , A23K20/189 , A23L29/06 , A23V2002/00 , A61K38/00 , A61K38/52 , C12Q1/533 , C12Y501/00 , C12Y501/01
摘要： This invention relates generally to enzymes, polynucleotides encoding the enzymes, the use of such polynucleotides and polypeptides and more specifically to enzymes having isomerase activity, e.g., racemase activity, e.g., amino acid racemase activity, alanine racemase activity, and/or epimerase activity, and/or catalyze the re¬ arrangement of atoms within a molecule, catalyze the conversion of one isomer into another, catalyze the conversion of an optically active substrate into a raceme, which is optically inactive, catalyze the interconversion of substrate enantiomers, catalyze the stereochemical inversion around the asymmetric carbon atom in a substrate having only one center of asymmetry, catalyze the stereochemical inversion of the configuration around an asymmetric carbon atom in a substrate having more than one asymmetric center, and/or catalyze the racemization of amino acids. Thus, the invention provides enzymes, compositions, methods for production of pharmaceutical compositions, pharmaceutical intermediates, antibiotics, sweeteners, peptide enzymes, peptide hormones, fuel and fuel additive compositions, foods and food additives, beverage and beverage additives, feeds and feed additives, drugs and drug additives, dietary supplements, textiles, wood, paper, pulp, and detergents comprising the polypeptides or polynucleotides in accordance with the invention.
摘要翻译：本发明一般涉及酶，编码酶的多核苷酸，这种多核苷酸和多肽的用途，更具体地涉及具有异构酶活性的酶，例如消旋酶活性，例如氨基酸消旋酶活性，丙氨酸消旋酶活性和/或差向异构酶活性，和/或催化分子内原子的重新排列，催化一种异构体转化为另一种异构体，催化光学活性底物转变成光学无活性的外消旋催化底物对映异构体的相互转化，催化立体化学在仅具有一个不对称中心的底物中的不对称碳原子周围反转，催化具有多于一个不对称中心的底物中不对称碳原子周围的构型的立体化学反转，和/或催化氨基酸的外消旋化。因此，本发明提供了用于生产药物组合物，药物中间体，抗生素，甜味剂，肽酶，肽激素，燃料和燃料添加剂组合物，食品和食品添加剂，饮料和饮料添加剂，饲料和饲料添加剂的酶，组合物，药物和药物添加剂，膳食补充剂，纺织品，木材，纸，纸浆和洗涤剂，其包含根据本发明的多肽或多核苷酸。

6. 发明申请

WO2008027501A3 LACCASES FOR PULP BIO-BLEACHING 审中-公开
公开(公告)号：WO2008027501A3
公开(公告)日：2008-03-06
申请号：PCT/US2007/019124
申请日：2007-08-31
申请人： VERENIUM CORPORATION , KEROVUO, Janne, Samuli , HAREMZA, Sylke , KOCH, Oliver , HABICHER, Tilo , ROBERTSON, Dan , DESANTIS, Grace , MCCANN, Ryan , LUGINBUHL, Peter
发明人： KEROVUO, Janne, Samuli , HAREMZA, Sylke , KOCH, Oliver , HABICHER, Tilo , ROBERTSON, Dan , DESANTIS, Grace , MCCANN, Ryan , LUGINBUHL, Peter
IPC分类号： C12N9/02 , C12N1/20 , C12N15/00 , C12Q1/00 , C12Q1/34 , C12Q1/68 , C12P21/06 , C12P21/04 , A61K38/44 , C07H21/04 , C07K1/00 , C07K16/00
摘要： Provided herein are isolated laccase enzymes and nucleic acids encoding them. Also provided are mediators for laccase reactions. Also provided herein are methods for using laccases to oxidize lignins and other phenolic and aromatic compounds, such as for bio-bleaching and decolorization of wood pulp under high temperature and pH conditions to facilitate a substantial reduction in use of bleaching chemicals, as well as for treatment of fibers.

7. 发明申请

WO2009088949A1 TRANSFERASES AND OXIDOREDUCTASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 审中-公开
标题翻译：转移和氧化还原，核酸编码及其制备和使用方法
公开(公告)号：WO2009088949A1
公开(公告)日：2009-07-16
申请号：PCT/US2008/088675
申请日：2008-12-31
申请人： VERENIUM CORPORATION , WEINER, David , LUGINBUHL, Peter , BUENO, Analia , CUENCA, Joslin , MARASCO, Erin
发明人： WEINER, David , LUGINBUHL, Peter , BUENO, Analia , CUENCA, Joslin , MARASCO, Erin
IPC分类号： C12N9/10 , C12N9/02 , C12Q1/48 , C12Q1/26 , C07K14/38 , C07K16/40 , C07K9/00 , A61K38/44 , A61K38/45
CPC分类号： C12N9/1096 , A21D8/042 , A61K38/00 , C12N9/0004 , C12N9/0006 , C12N9/0014 , C12N9/10 , C12N15/1137 , C12N15/63 , C12N15/86 , C12P7/10 , C12Q1/6876 , C12Y206/01021 , D06L4/40 , D06M16/003 , G01N33/573 , Y02E50/16 , Y02P20/52 , Y02T50/678
摘要： This invention relates generally to enzymes, polynucleotides encoding the enzymes, the use of such polynucleotides and polypeptides and more specifically to enzymes having transferase activity, e.g., transaminase activity, e.g., d-amino-acid transferase activity, and/or oxidoreductase activity, e.g., dehydrogenase activity, e.g., damino-acid dehydrogenase activity, and/or catalyze the transfer of a chemical group, catalyze transamination, catalyze the reaction: D-alanine + 2-oxoglutarate pyruvate + D-glutamate, and/or catalyze an oxidation-reduction reaction, catalyze the removal of hydrogen atoms, and/or catalyze the reaction: D-amino acid + H 2 O + acceptor a 2- oxo acid + NH 3 + reduced acceptor. Thus, the invention provides enzymes, compositions, methods for production of pharmaceutical compositions, pharmaceutical intermediates, antibiotics, sweeteners, peptide enzymes, peptide hormones, fuel and fuel additive compositions, foods and food additives, beverage and beverage additives, feeds and feed additives, drugs and drug additives, dietary supplements, textiles, wood, paper, pulp, and detergents comprising the polypeptides or polynucleotides in accordance with the invention.
摘要翻译：本发明一般涉及酶，编码酶的多核苷酸，这种多核苷酸和多肽的用途，更具体地涉及具有转移酶活性的酶，例如转氨酶活性，例如，d-氨基酸转移酶活性和/或氧化还原酶活性，例如，脱氢酶活性，例如脱氨酸脱氢酶活性和/或催化化学基团的转移，催化转氨酶，催化反应：D-丙氨酸+ 2-氧戊二酸酯<=>丙酮酸盐+ D-谷氨酸盐和/或催化氧化还原反应，催化氢原子的去除和/或催化反应：D-氨基酸+ H2O +受体3 +还原受体。因此，本发明提供了用于生产药物组合物，药物中间体，抗生素，甜味剂，肽酶，肽激素，燃料和燃料添加剂组合物，食品和食品添加剂，饮料和饮料添加剂，饲料和饲料添加剂的酶，组合物，药物和药物添加剂，膳食补充剂，纺织品，木材，纸，纸浆和洗涤剂，其包含根据本发明的多肽或多核苷酸。

8. 发明申请

WO2008095033A2 ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 审中-公开
标题翻译：用于处理木质纤维体的酶，编码它们的核酸以及制备和使用它们的方法
公开(公告)号：WO2008095033A2
公开(公告)日：2008-08-07
申请号：PCT/US2008/052517
申请日：2008-01-30
申请人： VERENIUM CORPORATION , SYNGENTA PARTICIPATIONS AG , CHANG, Cathy , STEGE, Justin, T. , ABOUSHADI, Nahla , DJORDJEVIC, Gordana , BURKE, Ellen , LUGINBUHL, Peter , DYCAICO, Mark , RICHARDSON, Toby , POLAND, John , HEFNER, Ying , MILES, Stacy, Marie
发明人： STEGE, Justin, T. , ABOUSHADI, Nahla , DJORDJEVIC, Gordana , BURKE, Ellen , LUGINBUHL, Peter , DYCAICO, Mark , RICHARDSON, Toby , POLAND, John , HEFNER, Ying , MILES, Stacy, Marie
CPC分类号： C12P19/14 , C12N9/2437 , C12N9/2445 , C12P7/04 , C12P19/02 , C12Y302/01021 , Y02E50/16 , Y02E50/17 , Y02E50/343
摘要： The invention provides polypeptides having a lignocellulolytic activity, e.g., a glycosyl hydrolase, a cellulase, an endoglucanase, a cellobiohydrolase, a beta- glucosidase, a xylanase, a mannanse, a xylosidase (e.g., a β- xylosidase), an arabinofuranosidase, and/or a glucose oxidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides that can enzymatically process (hydrolyze) sugarcane bagasse, i.e., for sugarcane bagasse degradation, or for biomass processing, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one embodiment, the invention provides thermostable and thermotolerant forms of polypeptides of the invention. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts; for example, the invention provides a multi-enzyme system that can hydrolyze polysaccharides in a bagasse component of sugarcane processed in sugar mills. The invention provides enzymes for the bioconversion of lignocellulosic residues into fermentable sugars; and these sugars can be used as a chemical feedstock for the production of ethanol and fuels, including biofuels such as bioethanol, biopropanol, biobutanol and biodiesels.
摘要翻译：
本发明提供了一种具有木质纤维素酶活性，例如，糖基水解酶，纤维素酶，内切葡聚糖酶，纤维二糖水解，β-葡糖苷酶，木聚糖酶，甘露聚糖酶，木糖苷酶的多肽（例如，β - 木糖苷酶），阿拉伯呋喃糖苷酶和/或葡萄糖氧化酶活性，编码这些多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。在一个方面，本发明提供了能够酶处理（水解）甘蔗渣，即用于甘蔗渣降解或用于生物质处理的多肽，以及编码这些酶的多核苷酸，以及制备和使用这些多核苷酸和多肽。在一个实施方案中，本发明提供了本发明的热稳定和耐热形式的多肽。本发明的多肽可以用于各种制药，农业和工业领域; 例如，本发明提供了一种多酶体系，其能够水解在糖厂中加工的甘蔗的甘蔗渣组分中的多糖。本发明提供了用于将木质纤维素残基生物转化成可发酵糖的酶; 这些糖可以用作生产乙醇和燃料的化学原料，包括生物燃料，如生物乙醇，生物丙醇，生物丁醇和生物柴油。

9. 发明申请

WO2008080093A2 AMYLASES AND GLUCOAMYLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 审中-公开
标题翻译： AMYLASES和GLUCOAMYLASES，编码它们的核酸以及制备和使用它们的方法
公开(公告)号：WO2008080093A2
公开(公告)日：2008-07-03
申请号：PCT/US2007/088631
申请日：2007-12-21
申请人： VERENIUM CORPORATION , SYNGENTA PARTICIPATIONS AG , SLUPSKA, Malgorzata , HAZLEWOOD, Geoff , CHANG, Cathy , LUGINBUHL, Peter , BURKE, Ellen , CAYOUETTE, Michelle , GUNAVARDENA, Uvini , GHASSEMIAN, Majid , SILVERSTONE, Aron , ZHANG, Yan
发明人： SLUPSKA, Malgorzata , HAZLEWOOD, Geoff , CHANG, Cathy , LUGINBUHL, Peter , BURKE, Ellen , CAYOUETTE, Michelle , GUNAVARDENA, Uvini , GHASSEMIAN, Majid , SILVERSTONE, Aron , ZHANG, Yan
IPC分类号： C12N9/28
CPC分类号： C12N9/96 , C12N9/2408 , C12N9/2414 , C12N9/2425 , C12N9/2428 , Y02E50/16 , Y02E50/17
摘要： In one aspect, the invention is directed to polypeptides having an amylase and/or glucoamylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of polysaccharide, oligosaccharide or starch into sugars. In one aspect, the invention provides delayed release compositions comprising an desired ingredient coated by a latex polymer coating. In alternative embodiments, enzymes are used to make biofuels, e.g., ethanol, butanol, propanol, or a gasoline-ethanol mix, including a bioethanol, biopropanol, biobutanol, or a biodiesel, or for any form of fuel or biomass processing.
摘要翻译：一方面，本发明涉及具有淀粉酶和/或葡糖淀粉酶活性的多肽，编码所述多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。在一个方面，本发明的多肽可以用作淀粉酶，例如α-淀粉酶，以催化多糖，寡糖或淀粉水解成糖。在一个方面，本发明提供了包含通过胶乳聚合物涂层涂覆的期望成分的延迟释放组合物。在替代实施方案中，使用酶来制造生物燃料，例如乙醇，丁醇，丙醇或汽油 - 乙醇混合物，包括生物乙醇，生物丙醇，生物丁醇或生物柴油，或用于任何形式的燃料或生物质处理。

10. 发明授权

EP2238261B1 Isomerases, nucleic acids encoding them and methods for making and using them 有权
标题翻译：异构酶，核酸，其编码和它们的制备方法和用途
公开(公告)号：EP2238261B1
公开(公告)日：2013-12-04
申请号：EP08870439.0
申请日：2008-12-22
申请人： Verenium Corporation
发明人： WEINER, David , BURKE, Ellen , LUGINBUHL, Peter , BUENO, Analia , CUENCA, Joslin , DE SOUZA, Mervyn, L. , KOLLMANN, Sherry
IPC分类号： C12N9/90 , C12Q1/533 , A61K38/52 , A01K67/027
CPC分类号： C12N9/90 , A01K67/0275 , A01K2217/05 , A01K2227/10 , A23G3/366 , A23G4/123 , A23G4/14 , A23K20/189 , A23L29/06 , A23V2002/00 , A61K38/00 , A61K38/52 , C12Q1/533 , C12Y501/00 , C12Y501/01

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式