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1. 发明授权

US08437838B2 Methods and devices for identifying overdetection of cardiac signals 有权
标题翻译：识别心脏信号过度检测的方法和装置
公开(公告)号：US08437838B2
公开(公告)日：2013-05-07
申请号：US13607256
申请日：2012-09-07
申请人： Jay A. Warren , Venugopal Allavatam , Rick Sanghera , Surekha Palreddy
发明人： Jay A. Warren , Venugopal Allavatam , Rick Sanghera , Surekha Palreddy
IPC分类号： A61B5/04 , A61B5/02 , A61N1/00
CPC分类号： A61B5/0452 , A61B5/0424 , A61B5/726
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In illustrative examples, sensed data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data.
摘要翻译：植入心脏监测和治疗装置如植入式心律转复除颤器中的信号分析方法，系统和装置。在说明性示例中，分析包括检测到的事件的感测数据以识别心脏事件的可能过度检测。在一些说明性示例中，当识别出过度检测时，可以修改数据以校正过度检测，以减少过度检测的影响或忽略过度检测的数据。

2. 发明申请

US20120197334A1 Methods and Devices for Accurately Classifying Cardiac Activity 有权
标题翻译：准确分类心脏活动的方法和设备
公开(公告)号：US20120197334A1
公开(公告)日：2012-08-02
申请号：US13436448
申请日：2012-03-30
申请人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam , Surekha Palreddy
发明人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam , Surekha Palreddy
IPC分类号： A61N1/365
CPC分类号： A61B5/4836 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61B5/0468 , A61B5/7203 , A61B5/7221 , A61B5/726 , A61B5/7264 , A61N1/3621 , A61N1/36514 , A61N1/36592 , A61N1/37 , A61N1/3987
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In some examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. Several examples emphasize the use of morphology analysis using correlation to static templates and/or inter-event correlation analysis.
摘要翻译：植入心脏监测和治疗装置如植入式心律转复除颤器中的信号分析方法，系统和装置。在一些示例中，分析包括检测到的事件的捕获数据以识别心脏事件的可能过度检测。在一些说明性示例中，当识别出过度检测时，可以修改数据以校正过度检测，以减少过度检测的影响或忽略过度检测的数据。几个例子强调使用与静态模板和/或事件间相关分析相关的形态分析。

3. 发明申请

US20100331904A1 Adaptive Confirmation of Treatable Arrhythmia in Implantable Cardiac Stimulus Devices 有权
标题翻译：可植入心脏刺激装置中可治疗性心律失常的自适应确认
公开(公告)号：US20100331904A1
公开(公告)日：2010-12-30
申请号：US12826241
申请日：2010-06-29
申请人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam
发明人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam
IPC分类号： A61N1/39 , A61N1/365
CPC分类号： A61N1/3987 , A61B5/0464 , A61N1/3622 , A61N1/3925 , A61N1/3943 , A61N1/3956
摘要： Methods and devices for adjusting therapy delivery decisions in an implantable cardiac stimulus device by observing cardiac activity following an initial identification of a treatable condition. In some examples, cardiac activity that appears benign is quantified and a therapy confirmation threshold is adjusted according to how much apparently benign cardiac activity is seen after an initial identification of a treatable condition. In other examples, a new threshold is applied following the initial identification of treatable condition, removing historical data preceding the initial identification from subsequent therapy delivery decisions.
摘要翻译：用于通过在初始识别可治疗病症后观察心脏活动来调整可植入心脏刺激装置中的治疗递送决定的方法和装置。在一些实例中，显示良性的心脏活动被定量，并且根据在可治疗病症的初始鉴定之后看到多少明显良性的心脏活动来调整治疗确认阈值。在其他示例中，在可治疗条件的初始识别之后应用新阈值，从随后的治疗递送决定中移除初始识别之前的历史数据。

4. 发明申请

US20100152799A1 Implantable Defibrillator Systems and Methods with Mitigations for Saturation Avoidance and Accommodation 有权
标题翻译：植入式除颤器系统和缓解饱和度的住院方法
公开(公告)号：US20100152799A1
公开(公告)日：2010-06-17
申请号：US12636575
申请日：2009-12-11
申请人： Rick Sanghera , Venugopal Allavatam , Surekha Palreddy , Jay A. Warren
发明人： Rick Sanghera , Venugopal Allavatam , Surekha Palreddy , Jay A. Warren
IPC分类号： A61N1/39
CPC分类号： A61N1/3704 , A61N1/048 , A61N1/0504 , A61N1/0563 , A61N1/3702 , A61N1/3968 , A61N1/3987
摘要： Methods and implantable devices that address response to, or avoidance of, likely non-cardiac voltages including afterpotentials from external or internal stimulus. Some examples are directed toward methods of operation in implantable medical devices, the methods configured for identifying saturation of input circuitry and mitigating the effects of such saturation. Some examples are directed toward implantable cardiac stimulus or monitoring devices that include methods for identifying saturated conditions and mitigating the effects of such saturation.
摘要翻译：解决可能的非心脏电压（包括来自外部或内部刺激的后电位）的响应或避免的方法和可植入装置。一些示例涉及可植入医疗设备中的操作方法，该方法被配置用于识别输入电路的饱和度并减轻这种饱和的影响。一些示例涉及可植入心脏刺激或监测装置，其包括用于识别饱和状况和减轻这种饱和的影响的方法。

5. 发明授权

US09149637B2 Adaptive confirmation of treatable arrhythmia in implantable cardiac stimulus devices 有权
标题翻译：可植入心脏刺激装置中可治疗心律失常的自适应确认
公开(公告)号：US09149637B2
公开(公告)日：2015-10-06
申请号：US12826241
申请日：2010-06-29
申请人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam
发明人： Jay A. Warren , Rick Sanghera , Venugopal Allavatam
IPC分类号： A61N1/39 , A61N1/365 , A61N1/362 , A61B5/0464
CPC分类号： A61N1/3987 , A61B5/0464 , A61N1/3622 , A61N1/3925 , A61N1/3943 , A61N1/3956
摘要： Methods and devices for adjusting therapy delivery decisions in an implantable cardiac stimulus device by observing cardiac activity following an initial identification of a treatable condition. In some examples, cardiac activity that appears benign is quantified and a therapy confirmation threshold is adjusted according to how much apparently benign cardiac activity is seen after an initial identification of a treatable condition. In other examples, a new threshold is applied following the initial identification of treatable condition, removing historical data preceding the initial identification from subsequent therapy delivery decisions.
摘要翻译：用于通过在初始识别可治疗病症后观察心脏活动来调整可植入心脏刺激装置中的治疗递送决定的方法和装置。在一些实例中，显示良性的心脏活动被定量，并且根据在可治疗病症的初始鉴定之后看到多少明显良性的心脏活动来调整治疗确认阈值。在其他示例中，在可治疗条件的初始识别之后应用新阈值，从随后的治疗递送决定中移除初始识别之前的历史数据。

6. 发明授权

US08565878B2 Accurate cardiac event detection in an implantable cardiac stimulus device 有权
标题翻译：在可植入心脏刺激装置中精确的心脏事件检测
公开(公告)号：US08565878B2
公开(公告)日：2013-10-22
申请号：US12399901
申请日：2009-03-06
申请人： Venugopal Allavatam , Surekha Palreddy , Rick Sanghera , Jay A. Warren
发明人： Venugopal Allavatam , Surekha Palreddy , Rick Sanghera , Jay A. Warren
IPC分类号： A61N1/36
CPC分类号： A61N1/3987 , A61B5/0245 , A61B5/0452 , A61B5/04525 , A61B5/726 , A61N1/365 , A61N1/3704
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In some illustrative examples, detected events are analyzed to identify changes in detected event amplitudes. When detected event amplitudes are dissimilar from one another, a first set of detection parameters may be invoked, and, when detected event amplitudes are similar to one another, a second set of detection parameters may be invoked. Additional methods determine whether the calculated heart rate is “high” or “low,” and then may select a third set of detection parameters for use when the calculated heart rate is high.
摘要翻译：植入式心脏监测和治疗装置如植入式心律转复除颤器中的信号分析方法，系统和装置。在一些说明性示例中，分析检测到的事件以识别检测到的事件振幅的变化。当检测到的事件幅度彼此不同时，可以调用第一组检测参数，并且当检测到的事件幅度彼此相似时，可以调用第二组检测参数。另外的方法确定计算的心率是“高”还是“低”，然后可以选择第三组检测参数，以便在计算心率高时使用。

7. 发明申请

US20110098775A1 Adaptive Waveform Appraisal in an Implantable Cardiac System 有权
标题翻译：植入式心脏系统中的自适应波形评估
公开(公告)号：US20110098775A1
公开(公告)日：2011-04-28
申请号：US12913647
申请日：2010-10-27
申请人： Venugopal Allavatam , Rick Sanghera , Jay A. Warren
发明人： Venugopal Allavatam , Rick Sanghera , Jay A. Warren
IPC分类号： A61N1/08
CPC分类号： A61B5/04012 , A61N1/37 , A61N1/3706 , A61N1/3987
摘要： Methods and implantable devices for cardiac signal analysis. The methods and devices make use of waveform appraisal techniques to distinguish event detections into categories for suspect events and waveform appraisal passing events. When adjustments are made to the data entering analysis for waveform appraisal, the waveform appraisal thresholds applied are modified as well. For example, when the data analysis window for waveform appraisal changes in length, a waveform appraisal threshold is modified. Other changes, including changes in sensing characteristics with which waveform appraisal operates may also result in changes to the waveform appraisal threshold including changes in gain, sensing vector, activation of other devices, implantee posture and other examples which are explained.
摘要翻译：用于心脏信号分析的方法和可植入装置。方法和设备利用波形评估技术将事件检测区分为可疑事件和波形评估传递事件的类别。当对输入波形评估分析的数据进行调整时，也会修改应用的波形评估阈值。例如，当波形评估的数据分析窗口长度变化时，波形评估阈值被修改。其他变化，包括波形评估操作的检测特性的变化也可能导致波形评估阈值的变化，包括增益，感测向量，其他设备的激活，植入者姿势以及其他所示示例的变化。

8. 发明申请

US20090259271A1 Methods and Devices for Accurately Classifying Cardiac Activity 有权
标题翻译：准确分类心脏活动的方法和设备
公开(公告)号：US20090259271A1
公开(公告)日：2009-10-15
申请号：US12399914
申请日：2009-03-06
申请人： Venugopal Allavatam , Surekha Palreddy , Rick Sanghera , Jay A. Warren
发明人： Venugopal Allavatam , Surekha Palreddy , Rick Sanghera , Jay A. Warren
IPC分类号： A61N1/365
CPC分类号： A61N1/3987 , A61B5/024 , A61B5/04014 , A61B5/0452 , A61B5/6847 , A61B5/726 , A61N1/3704 , A61N1/3956
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In illustrative examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. New methods for organizing the use of morphology and rate analysis in an overall architecture for rhythm classification and cardiac signal analysis are also discussed.
摘要翻译：植入心脏监测和治疗装置如植入式心律转复除颤器中的信号分析方法，系统和装置。在说明性示例中，分析包括检测到的事件的捕获数据以识别心脏事件的可能过度检测。在一些说明性示例中，当识别出过度检测时，可以修改数据以校正过度检测，以减少过度检测的影响或忽略过度检测的数据。还讨论了在节律分类和心脏信号分析的整体架构中组织使用形态学和速率分析的新方法。

9. 发明申请

US20120271185A1 Robust Rate Calculation in an Implantable Cardiac Stimulus or Monitoring Device 有权
标题翻译：可植入心脏刺激或监测装置中的稳健率计算
公开(公告)号：US20120271185A1
公开(公告)日：2012-10-25
申请号：US13451393
申请日：2012-04-19
申请人： Rick Sanghera , Venugopal Allavatam , Jay A. Warren , Mark R. Schroeder
发明人： Rick Sanghera , Venugopal Allavatam , Jay A. Warren , Mark R. Schroeder
IPC分类号： A61B5/0468
CPC分类号： A61B5/0452 , A61B5/0245 , A61B5/042 , A61B5/046 , A61B5/0468 , A61B5/7203 , A61B5/7221 , A61N1/36592 , A61N1/3704 , A61N1/3956
摘要： Devices and methods for analyzing cardiac signal data. An illustrative method includes identifying a plurality of detected events and measuring intervals between the detected events for use in rate estimation. In the illustrative embodiment, a set of intervals is used to make the rate estimation by first discarding selected intervals from the set. The remaining intervals are then used to calculate an estimated interval, for example by averaging the remaining intervals.
摘要翻译：用于分析心脏信号数据的装置和方法。一种说明性方法包括识别多个检测到的事件并测量检测到的事件之间的间隔，以用于速率估计。在说明性实施例中，使用一组间隔通过首先从组中丢弃所选择的间隔来进行速率估计。然后，剩余的间隔用于计算估计的间隔，例如通过对剩余间隔进行平均。

10. 发明授权

US08265749B2 Methods and devices for accurately classifying cardiac activity 有权
公开(公告)号：US08265749B2
公开(公告)日：2012-09-11
申请号：US12637438
申请日：2009-12-14
申请人： Venugopal Allavatam , Surekha Palreddy , Rick Sanghera , Jay A. Warren
发明人： Venugopal Allavatam , Surekha Palreddy , Rick Sanghera , Jay A. Warren
IPC分类号： A61B5/0452
CPC分类号： A61N1/3987 , A61B5/024 , A61B5/04014 , A61B5/0452 , A61B5/6847 , A61B5/726 , A61N1/3704 , A61N1/3956
摘要： Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In illustrative examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. New methods for organizing the use of morphology and rate analysis in an overall architecture for rhythm classification and cardiac signal analysis are also discussed.

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