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1. 发明申请

US20100262020A1 PROBE APPARATUS FOR RECOGNIZING ABNORMAL TISSUE 审中-公开
标题翻译：用于识别异常组织的探针装置
公开(公告)号：US20100262020A1
公开(公告)日：2010-10-14
申请号：US12684837
申请日：2010-01-08
申请人： Vadim Backman , Bradley Gould , Andrew Cittadine , Jeremy Rogers , Hemant Roy
发明人： Vadim Backman , Bradley Gould , Andrew Cittadine , Jeremy Rogers , Hemant Roy
IPC分类号： A61B6/00
CPC分类号： A61B5/0084
摘要： The present invention relates to probe apparatuses and component combinations thereof that are used to recognize possibly abnormal living tissue using a detected early increase in microvascular blood supply and corresponding applications. In one embodiment there is disclosed an apparatus that emits broadband light obtained from a light source onto microvasculature of tissue disposed within a human body and receives interacted light that is obtained from interaction of the broadband light with the microvasculature for transmission to a receiver. Different further embodiments include combinations of optical fibers, polarizers and lenses that assist in the selection of a predetermined depth profile of interacted light. In another embodiment, a kit apparatus is described that has various probe tips and/or light transmission elements that provide for various combinations of predetermined depth profiles of interacted light. In a further embodiment, a method of making a spectral data probe for depth range detection selectivity for detection of blood within microvasculature of tissue is described.
摘要翻译：本发明涉及用于利用检测到的微血管血液供应的早期增加和相应应用来识别可能的异常活体组织的探针装置及其组分组合。在一个实施例中，公开了一种将从光源发射的宽带光发射到设置在人体内的组织的微血管上的装置，并且接收从宽带光与微血管系统的相互作用获得的相互作用的光，以便传输到接收器。不同的另外的实施例包括有助于选择相互作用的光的预定深度分布的光纤，偏振器和透镜的组合。在另一个实施例中，描述了具有各种探针尖端和/或光透射元件的套件装置，其提供了相互作用的光的预定深度分布的各种组合。在另一个实施方案中，描述了制备用于深度范围检测选择性的光谱数据探针以检测组织微血管内的血液的方法。

2. 发明授权

US10813553B2 Handheld optical probe in combination with a fixed-focus fairing 有权
公开(公告)号：US10813553B2
公开(公告)日：2020-10-27
申请号：US14001556
申请日：2012-03-01
申请人： Stephen A. Boppart , Paul Scott Carney , Andrew Cittadine
发明人： Stephen A. Boppart , Paul Scott Carney , Andrew Cittadine
IPC分类号： A61B5/00 , G01B9/02 , G01B11/00
摘要： An intraoperative probe and a system for optically imaging a surgically significant volume of tissue or other scattering medium. An illumination source generates an illuminating beam that is conveyed to the vicinity of the tissue and a beam splitter, that may be no more than an optical phase reference, splits the illuminating beam into a sample beam along a sample beam path and a reference beam along a reference beam path. A scanning mechanism scans a portion of the sample beam across a section of the scattering medium, while a detector detects return beams from both the reference beam path and the sample beam path and generates an interference signal. A processor computationally moves an effective focus of the sample beam without physical variation of focus of the sample beam. The probe may have a sterilizable fairing that may be detachable.

3. 发明申请

US20130345558A1 Hand-Held Fixed-Focus Optical Probe 审中-公开
标题翻译：手持固定焦点光学探头
公开(公告)号：US20130345558A1
公开(公告)日：2013-12-26
申请号：US14001556
申请日：2012-03-01
申请人： Stephen A. Boppart , Paul Scott Carney , Andrew Cittadine
发明人： Stephen A. Boppart , Paul Scott Carney , Andrew Cittadine
IPC分类号： A61B5/00
摘要： An intraoperative probe and a system for optically imaging a surgically significant volume of tissue or other scattering medium. An illumination source generates an illuminating beam that is conveyed to the vicinity of the tissue and a beam splitter, that may be no more than an optical phase reference, splits the illuminating beam into a sample beam along a sample beam path and a reference beam along a reference beam path. A scanning mechanism scans a portion of the sample beam across a section of the scattering medium, while a detector detects return beams from both the reference beam path and the sample beam path and generates an interference signal. A processor computationally moves an effective focus of the sample beam without physical variation of focus of the sample beam. The probe may have a sterilizable fairing that may be detachable.
摘要翻译：术中探针和用于光学地成像外科手术显着体积的组织或其它散射介质的系统。照明源产生被传送到组织附近的照明光束，并且可以不超过光相位参考的分束器将照明光束沿着样本光束路径和参考光束沿着样本光束分裂参考光束路径。扫描机构扫描样品束的一部分横跨散射介质的一部分，而检测器检测来自参考光束路径和样本光束路径的返回光束，并产生干涉信号。处理器计算地移动样本波束的有效焦点，而样品波束的焦点没有物理变化。探头可以具有可拆卸的可消毒整流罩。

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