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1. 发明申请

WO1998004252A1 ANTIMALARIAL AND ANTI-BABESIOSIS AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME 审中-公开
标题翻译：抗生素和抗骨质疏松剂及含有其的药物组合物
公开(公告)号：WO1998004252A1
公开(公告)日：1998-02-05
申请号：PCT/FR1997001336
申请日：1997-07-17
申请人： VIRBAC S.A. , VIAL, Henri , CALAS, Michèle , ANCELIN, Marie-Laure , GIRAL, Louis
发明人： VIRBAC S.A.
IPC分类号： A61K31/14
CPC分类号： C07D207/08 , A61K31/14 , A61K31/40 , A61K31/4025 , A61K31/4545 , A61K31/5377 , C07C211/63 , C07C215/90 , C07C217/08 , C07D211/22 , C07D295/13 , Y02A50/411
摘要： Pharmaceutical compositions having antimalarial and anti-babesiosis activity, the active principles of said compositions, and the use thereof for preparing antimalarial drugs, are disclosed.
摘要翻译：公开了具有抗疟疾和抗宝贝活性的药物组合物，所述组合物的活性成分及其制备抗疟疾药物的用途。

2. 发明申请

WO1996033743A1 WATER SOLUBLE, POWDER FORM COMPOSITIONS AND APPLICATIONS THEREOF 审中-公开
标题翻译：水溶性，粉末形式组合物及其应用
公开(公告)号：WO1996033743A1
公开(公告)日：1996-10-31
申请号：PCT/FR1996000635
申请日：1996-04-25
申请人： VIRBAC S.A. , DERRIEU, Guy , POUGNAS, Jean-Luc , BROUSSAUD, Olivier
发明人： VIRBAC S.A.
IPC分类号： A61K47/02
CPC分类号： A61K47/02 , Y10S514/951
摘要： Water soluble, powder form compositions suitable for completely and rapidly dissolving active ingredients which usually only dissolve in water in the presence of base salts, such as antibiotics of the betalactamide family, for example penicillins and their derivatives, cephalosporins and their derivatives, or other active ingredients such as sulphamides and quinolones, for oral absorption thereof and their applications. The water soluble powder form compositions contain, in combination and in powder form, at least one water soluble active ingredient, not in salt form, and with an exclusively alkaline pH, an excess of one or more strong base salts, and one or more buffers comprising one or more substances and capable of maintaining the pH of the medium at a level below the normal solubilisation pH of said active ingredient. Aqueous solution compositions obtained from said powder form compositions are also described.
摘要翻译：适用于完全和快速溶解通常仅在碱盐存在下溶解于水中的活性成分的水溶性粉末形式组合物，例如β-乳酸酰胺家族的抗生素，例如青霉素及其衍生物，头孢菌素及其衍生物或其它活性成分成分如硫胺和喹诺酮，用于口服吸收及其应用。水溶性粉末形式组合物组合含有粉末形式的至少一种水溶性活性成分，不是盐形式，并且具有纯碱性pH，过量的一种或多种强碱盐和一种或多种缓冲液包含一种或多种物质并且能够将培养基的pH保持在低于所述活性成分的正常增溶pH的水平。还描述了由所述粉末形式组合物获得的水溶液组合物。

3. 发明申请

WO1998020005A1 ARYLOXYPROPANOLAMINE DERIVATIVES, METHOD OF PREPARATION AND APPLICATIONS THEREOF 审中-公开
标题翻译：芳族聚异戊二烯衍生物，其制备方法及其应用
公开(公告)号：WO1998020005A1
公开(公告)日：1998-05-14
申请号：PCT/FR1997001963
申请日：1997-11-03
申请人： VIRBAC S.A. , ARCHIMBAULT, Philippe , LECLERC, Gérard , STROSBERG, Arthur, Donny , PIETRI-ROUXEL, France
发明人： VIRBAC S.A.
IPC分类号： C07D317/66
CPC分类号： C07C217/30 , A23K20/111 , A23K20/116 , C07C217/58 , C07C217/84 , C07D317/58 , C07D317/66
摘要： The invention concerns aryloxypropanolamine derivatives having at least an anti-diabetic and anti-fat activity and their methods of preparation and applications, particularly as human and veterinary medicine and animal food additive. These derivatives comply with the general formula (I) in which R>2 2 2 2 3 2 3 3 2 2 2 x 5
摘要翻译：本发明涉及至少具有抗糖尿病和抗脂肪活性的芳氧基丙胺胺衍生物及其制备和应用的方法，特别是作为人和兽医药物和动物食品添加剂。这些衍生物符合通式（I），其中R> 2 <表示下列基团之一：-CH 2，-CH 2，-CH 2，-CH（CH 3） CH 2， - （CH 3）= CH - ， - C（CH 3）2 - ， - CH 2， - 或 - Q表示：（i）用苯基决定的苯基3,4-二取代的亚烷基二氧基，未取代的苯并二氧杂环己烷单元，未取代的苯并间二氧杂环戊烯单元或2-取代的苯并二氧杂环己烷单元，（ii）苯基 3和/或4-取代基，（iii）包含至少两个缩合循环的缩合多环烃，（iv）环状烃系统，任选地交联，并构成包含1,2或3个循环的环烷烃。

4. 发明申请

WO1997013508A1 TOPICAL LIQUID COMPOSITION, METHOD FOR PREPARING SAME AND USES THEREOF 审中-公开
标题翻译：局部液体组合物，其制备方法及其用途
公开(公告)号：WO1997013508A1
公开(公告)日：1997-04-17
申请号：PCT/FR1996001589
申请日：1996-10-11
申请人： VIRBAC S.A. , BEUVRY, Vincent
发明人： VIRBAC S.A.
IPC分类号： A61K31/275
CPC分类号： A61K9/0017 , A61K31/277
摘要： A topical liquid endoparasiticidal composition for treating helminthic diseases caused by flukes in homoiothermic animals, a method for preparing said composition and the uses thereof are disclosed. Said composition essentially consists of a solution of closantel soda salt in at least one non-aqueous solvent selected from the group which consists of polyalcohols, ethers thereof and mixtures thereof.
摘要翻译：公开了一种用于治疗由均质动物引起的吸虫引起的蠕虫病的局部用液体杀寄生组织物，制备该组合物的方法及其应用。所述组合物基本上由钠盐在至少一种选自多元醇，其醚及其混合物的非水溶剂中的溶液组成。

5. 发明申请

WO1998017277A1 AMIDINE COMPOUNDS FOR USE IN SYSTEMIC TREATING ECTO AND/OR ENDO PARASITIC DISEASES 审中-公开
标题翻译：用于系统治疗ECTO和/或ENDO PARASITIC疾病的氨基化合物
公开(公告)号：WO1998017277A1
公开(公告)日：1998-04-30
申请号：PCT/EP1997005920
申请日：1997-10-21
申请人： VIRBAC S.A. , DERRIEU, Guy , BEUVRY, Vincent , GOZLAN, Thierry
发明人： VIRBAC S.A.
IPC分类号： A61K31/44
CPC分类号： A61K45/06 , A01N47/40 , A61K31/44 , A01N43/40 , A01N2300/00
摘要： The invention provides compounds and compositions for killing ecto and/or endo parasites which comprises administering to a warm blooded animal at least a systemically effective amount of an amidine of general formula (I) wherein A represents an optionally substituted C1-C5 alkyl and preferably a C1-C3 alkyl, and Z represents an optionally substituted C1-C5 alkyl, preferably a C1-C3 alkyl.
摘要翻译：本发明提供用于杀死ecto和/或内寄生虫的化合物和组合物，其包括向温血动物施用至少全身有效量的通式（I）的脒，其中A表示任选取代的C 1 -C 5烷基，优选 C 1 -C 3烷基，Z表示任选取代的C 1 -C 5烷基，优选C 1 -C 3烷基。

6. 发明申请

WO1989001045A1 LEISHMANIA-SPECIFIC ANTIGENS, PROCESS FOR PREPARING THEM, ANTIGENIC PROFILES CONTAINING THESE ANTIGENS AND THEIR APPLICATION TO THE DIAGNOSIS OF VISCERAL LEISHMANIASIS 审中-公开
标题翻译： LEISHMANIA特异性抗原，制备它们的方法，含有这些抗原的抗原型及其应用于粘膜感染的诊断
公开(公告)号：WO1989001045A1
公开(公告)日：1989-02-09
申请号：PCT/FR1988000400
申请日：1988-08-02
申请人： INSTITUT PASTEUR , UNIVERSITE DE COMPIEGNE (I.T.S.) , VIRBAC S.A. , BERNEMAN, Armand , ROLLAND, Xavier
发明人： INSTITUT PASTEUR , UNIVERSITE DE COMPIEGNE (I.T.S.) , VIRBAC S.A.
IPC分类号： C12P21/00
CPC分类号： C07K14/44 , C07K16/20 , G01N33/56905 , Y02A50/55
摘要： The invention concerns leishmania-specific antigens, the process for preparing them, and antigenic profiles containing these antigens. Said antigens are recognized in a specific manner by the sera of persons or animals, especially dogs, suffering from visceral leishmaniasis, which do not exhibit cross-reactions with the sera of patients suffering from other diseases. Applications to the diagnosis of visceral leishmaniasis.

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