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1. 发明申请

WO2009042489A2 DYNAMIC ROD 审中-公开
标题翻译：动态ROD
公开(公告)号：WO2009042489A2
公开(公告)日：2009-04-02
申请号：PCT/US2008/076815
申请日：2008-09-18
申请人： VERTIFLEX, INC. , ALTARAC, Moti , REGLOS, Joey Camia , HAYES, Stanley Kyle , KIM, Daniel H.
发明人： ALTARAC, Moti , REGLOS, Joey Camia , HAYES, Stanley Kyle , KIM, Daniel H.
IPC分类号： A61B17/70 , A61B17/58
CPC分类号： A61B17/7023 , A61B17/6491 , A61B17/7005 , A61B17/7025 , A61B17/7028 , A61B17/7031
摘要： A dynamic rod implantable into a patient and connectable between two vertebral anchors in adjacent vertebral bodies is provided. The rod fixes the adjacent vertebral bodies dynamically providing immediate postoperative stability and support of the spine. The rod comprises a first rod portion having a first engaging portion connected to a second rod portion having a second engaging portion. The rod includes at least a one bias element configured to bias a deflection or translation of the first rod portion relative to the second rod portion. The first engaging portion includes at least one side or integral spring formed in the first engaging portion to bias a deflection of the second rod portion relative to the first rod portion. The rod permits relative movement of the first and second rod portions allowing the rod to carry some of the natural flexion and extension moments that the spine is subject to.
摘要翻译：提供了一种可植入患者并可连接在相邻椎体内的两个椎骨锚之间的动态杆。该杆动态地固定相邻的椎体，为脊柱提供即时的术后稳定性和支撑。该杆包括第一杆部分，该第一杆部分具有连接到具有第二接合部分的第二杆部分的第一接合部分。该杆包括至少一个偏置元件，该偏置元件被配置为偏置第一杆部分相对于第二杆部分的偏转或平移。第一接合部分包括形成在第一接合部分中的至少一个侧面或一体式弹簧，以偏压第二杆部分相对于第一杆部分的偏转。杆允许第一和第二杆部分的相对运动，从而允许杆承载脊柱所经受的一些自然的弯曲和伸展力矩。

2. 发明申请

WO2009100190A2 DYNAMIC ROD 审中-公开
标题翻译：动态ROD
公开(公告)号：WO2009100190A2
公开(公告)日：2009-08-13
申请号：PCT/US2009/033174
申请日：2009-02-05
申请人： VERTIFLEX, INC. , HAYES, Stanley Kyle , REGLOS, Joey Camia , ALTARAC, Moti , KIM, Daniel H.
发明人： HAYES, Stanley Kyle , REGLOS, Joey Camia , ALTARAC, Moti , KIM, Daniel H.
IPC分类号： A61B17/70 , A61F2/44
CPC分类号： A61B17/7005 , A61B17/7004 , A61B17/7013 , A61B17/7023 , A61B17/7025 , A61B17/7028
摘要： A dynamic rod implantable into a patient and connectable between two vertebral anchors in adjacent vertebral bodies is provided. The dynamic rod fixes the vertebral bodies together in a dynamic fashion providing immediate postoperative stability and support of the spine. The dynamic rod comprises a first rod portion and a second rod portion connected together. The dynamic rod further includes at least a one bias element configured to provide a bias force in response to deflection or translation of the first rod portion relative to the second rod portion. The dynamic rod includes a locking construct which advantageously enables the extension and/or angulation of one rod portion with respect to the other rod portion to be reversibly locked in position. The dynamic rod permits relative movement of the first and second rod portions allowing the rod to carry some of the natural flexion and extension moments of the spine.
摘要翻译：提供了植入患者体内并可在相邻椎体内的两个椎骨锚固件之间连接的动态杆。动态杆将椎体以动态方式固定在一起，提供立即术后稳定性和支撑脊柱。动态杆包括连接在一起的第一杆部分和第二杆部分。动态杆还包括至少一个偏置元件，其构造成响应于第一杆部分相对于第二杆部分的偏转或平移而提供偏置力。动态杆包括锁定构造，其有利地使得一个杆部分相对于另一个杆部分的延伸和/或成角可逆地锁定在适当位置。动态杆允许第一和第二杆部分的相对运动，允许杆承载脊柱的一些自然弯曲和伸展力矩。

3. 发明申请

WO2009114479A2 INTERSPINOUS PROCESS SPACER INSTRUMENT SYSTEM WITH DEPLOYMENT INDICATOR 审中-公开
标题翻译：具有部署指示器的互动过程间隔仪器系统
公开(公告)号：WO2009114479A2
公开(公告)日：2009-09-17
申请号：PCT/US2009/036561
申请日：2009-03-09
申请人： VERTIFLEX, INC. , TEBBE, Shawn , ALTARAC, Moti , KIM, Daniel H.
发明人： TEBBE, Shawn , ALTARAC, Moti , KIM, Daniel H.
IPC分类号： A61B17/70 , A61F2/44 , A61B17/88
CPC分类号： A61B17/7065
摘要： A percutaneous and minimally invasive instrument system for implanting an interspinous process spacer into a patient is disclosed. The insertion instrument system includes an inserter and a driver. The inserter is configured to releasably clamp to an interspinous process spacer for its delivery, implantation and deployment. The driver is configured for removable insertion into a proximal end of a passageway of the inserter. The driver has a distal spacer engaging portion configured to engage that part of the spacer requiring activation for the deployment of the spacer from at least one undeployed configuration to at least one deployed configuration and vice versa. As the spacer goes from the undeployed to the deployed configuration and vice versa, the system advantageously provides a degree of deployment information to the user via at least one deployment indicator.
摘要翻译：公开了一种用于将棘突间间隔物植入患者体内的经皮和微创手术系统。插入仪器系统包括插入器和驱动器。插入器构造成可释放地夹紧到棘突间间隔件用于其递送，植入和展开。驱动器被配置为可移除地插入到插入器的通道的近端中。驱动器具有远侧间隔件接合部分，其构造成接合需要激活的间隔件的该部分以将间隔件从至少一个未部署构造部署到至少一个部署构造，反之亦然。当间隔物从未部署到部署配置并且反之亦然时，系统有利地通过至少一个部署指示器向用户提供一定程度的部署信息。

4. 发明申请

WO2009086010A2 SPACER INSERTION INSTRUMENT 审中-公开
公开(公告)号：WO2009086010A2
公开(公告)日：2009-07-09
申请号：PCT/US2008/087527
申请日：2008-12-18
申请人： VERTIFLEX, INC. , ALTARAC, Moti , TEBBE, Shawn , KIM, Daniel H.
发明人： ALTARAC, Moti , TEBBE, Shawn , KIM, Daniel H.
IPC分类号： A61B17/56 , A61B17/34
CPC分类号： A61B17/7074 , A61B17/025 , A61B17/7062 , A61B17/7065 , A61B17/7067 , A61B2017/00004 , A61B2017/0256 , A61F2/0077
摘要： A percutaneous and minimally invasive instrument for inserting an interspinous process spacer into a patient is disclosed. The instrument includes a first assembly connected to a handle assembly. The first assembly includes an inner shaft located inside an outer shaft and configured for translational motion with respect to the outer shaft. The relative translational motion causes one of the outer or inner shafts to move with respect to the other and thereby deflect at least one prong formed on one of the inner or outer shafts wherein such deflection causes engagement with a juxtapositioned interspinous spacer. The instrument further includes a driver configured for removable insertion into a proximal end of a passageway of the instrument. The driver has a distal spacer engaging portion configured to engage that part of the spacer requiring activation for deployment of the spacer from an undeployed configuration to a deployed configuration and vice versa.
摘要翻译：公开了一种用于将棘突间间隔物插入患者的经皮且微创的器械。该仪器包括连接到手柄组件的第一组件。第一组件包括内轴，该内轴位于外轴的内部并且被配置为相对于外轴平移运动。相对平移运动导致外轴或内轴中的一个相对于另一个移动，并由此偏转形成在内轴或外轴中的一个上的至少一个叉，其中这种偏转导致与并置的棘突间间隔物接合。器械还包括构造成可移除地插入器械的通道的近端中的驱动器。驱动器具有远端间隔件接合部分，该远端间隔件接合部分配置成接合需要激活的间隔件的该部分以将间隔件从未展开构型展开到展开构型，反之亦然。

5. 发明申请

WO2006099285A2 PERCUTANEOUS ENDOSCOPIC ACCESS TOOLS FOR THE SPINAL EPIDURAL SPACE AND RELATED METHODS OF TREATMENT 审中-公开
标题翻译：椎间盘突出部位内窥镜获取工具及相关治疗方法
公开(公告)号：WO2006099285A2
公开(公告)日：2006-09-21
申请号：PCT/US2006/008888
申请日：2006-03-10
申请人： THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , SPINE VIEW, INC. , KIM, Daniel H. , CHIN, Singfatt
发明人： KIM, Daniel H. , CHIN, Singfatt
IPC分类号： A61F7/00 , A61F7/12 , A61B17/58 , A61B1/00 , A61B17/60
CPC分类号： A61B17/00234 , A61B17/0218 , A61B17/320036 , A61B17/3421 , A61B18/1477 , A61B18/22 , A61B2017/003 , A61B2017/00557 , A61B2017/22038 , A61B2017/3445 , A61B2018/1425 , A61B2018/143 , A61B2018/1475 , A61B2090/306 , A61B2090/3614 , A61F2/4611 , A61F2002/4627
摘要： Several alternative spinal access devices are described. A number of alternative methods for performing therapies in the spinal region using the described spinal access devices are also described.
摘要翻译：描述了几种替代的脊柱入路装置。还描述了使用所描述的脊椎进入装置在脊柱区域中进行治疗的许多替代方法。

6. 发明申请

WO2007142617A2 FABRICATION AND USE OF BIOCOMPATIBLE MATERIALS FOR TREATING AND REPAIRING HERNIATED SPINAL DISCS 审中-公开
标题翻译：生物化学材料的治疗和使用用于治疗和修复接受治疗的脊髓损伤
公开(公告)号：WO2007142617A2
公开(公告)日：2007-12-13
申请号：PCT/US2006/018856
申请日：2006-05-15
申请人： SARATECH, INC. , THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , KIM, Daniel H. , FRANK, Curtis W.
发明人： KIM, Daniel H. , FRANK, Curtis W.
IPC分类号： A61F2/44
CPC分类号： A61F2/442 , A61B17/7095 , A61B17/8836 , A61F2/441 , A61F2/4611 , A61F2002/0086 , A61F2002/009 , A61F2002/30032 , A61F2002/30062 , A61F2002/30075 , A61F2002/30224 , A61F2002/30235 , A61F2002/30583 , A61F2002/30588 , A61F2002/30601 , A61F2002/30677 , A61F2002/3092 , A61F2002/3093 , A61F2002/30932 , A61F2002/30971 , A61F2002/4435 , A61F2002/444 , A61F2002/4627 , A61F2002/4685 , A61F2210/0004 , A61F2210/0061 , A61F2210/0085 , A61F2230/0069 , A61F2250/003 , A61L27/18 , A61L27/56 , A61L2400/06 , A61L2430/38 , C08L75/04
摘要： The present invention involves the fabrication and use of biocompatible polymers that are injected percutaneously into the inner portion of a defective region of a spinal disc and swell or expand or subsequently cure in situ to form a disc nucleus prosthesis. The polymers may be synthetic or natural (e.g., collagen), and may be provided in forms including, but not limited to hydrogels, compressible foams, cords, balloons, etc. Subsequent to injection into a target space or void within the disc, one or more cell binding agents, growth factors, and/or drugs on or within the cured polymer then interact with the remaining portion of the disc to support tissue ingrowth and to achieve a higher probability of biological mimicking.
摘要翻译：本发明涉及生物相容性聚合物的制造和使用，所述生物相容性聚合物经皮注射到脊椎盘的缺陷区域的内部并膨胀或膨胀或随后在原位固化以形成椎间盘假体。聚合物可以是合成的或天然的（例如胶原），并且可以以包括但不限于水凝胶，可压缩泡沫，帘线，气球等的形式提供。在注入到盘中的目标空间或空隙中之后，一个或更多的细胞粘附剂，生长因子和/或药物在固化的聚合物上或内部，然后与盘的剩余部分相互作用以支持组织向内生长并实现更高的生物模拟概率。

7. 发明申请

WO2007124201A2 DEVICES, SYSTEMS AND METHODS FOR TREATING INTERVERTEBRAL DISCS 审中-公开
标题翻译：用于治疗椎间盘的装置，系统和方法
公开(公告)号：WO2007124201A2
公开(公告)日：2007-11-01
申请号：PCT/US2007/062689
申请日：2007-02-23
申请人： SARATECH, INC. , KIM, Daniel H.
发明人： KIM, Daniel H.
IPC分类号： A61F2/44
CPC分类号： A61F2/442 , A61F2/4611 , A61F2002/30062 , A61F2002/30092 , A61F2002/30576 , A61F2002/30579 , A61F2002/4435 , A61F2002/4495 , A61F2002/4627 , A61F2210/0004 , A61F2210/0014 , A61F2310/00023 , A61F2310/0097
摘要： Devices, systems, and methods are provided for treating intervertebral discs. In one embodiment, the systems include instruments for implanting the disc repair devices in a minimally invasive manner. The methods are directed to the minimally invasive implantation of one or more of the disc repair devices to within the intervertebral disc.
摘要翻译：提供了用于治疗椎间盘的装置，系统和方法。在一个实施例中，系统包括用于以微创方式植入椎间盘修复装置的器械。这些方法涉及将一个或多个椎间盘修复装置的微创植入到椎间盘内。

8. 发明申请

WO2007106079A2 PERCUTANEOUS ACCESS AND VISUALIZATION OF THE SPINE 审中-公开
标题翻译：皮肤的皮肤访问和可视化
公开(公告)号：WO2007106079A2
公开(公告)日：2007-09-20
申请号：PCT/US2006/008576
申请日：2006-03-10
申请人： THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , SPINE VIEW, INC. , KIM, Daniel H. , CHIN, Singfatt
发明人： KIM, Daniel H. , CHIN, Singfatt
IPC分类号： A61B1/00
CPC分类号： A61B1/018 , A61B1/00082 , A61B1/00085 , A61B1/3135 , A61B17/0218 , A61B18/14 , A61B2090/373
摘要： Devices, systems and methods are provided for the percutaneous access and visualization of the spine for the purposes of diagnosing and/or treating a target area of the spine or the surrounding tissue.
摘要翻译：为了诊断和/或治疗脊柱或周围组织的目标区域，提供用于经皮进入和可视化脊柱的装置，系统和方法。

9. 发明申请

WO2006045091A3 SYSTEMS AND METHODS FOR POSTERIOR DYNAMIC STABILIZATION OF THE SPINE 审中-公开
公开(公告)号：WO2006045091A3
公开(公告)日：2006-04-27
申请号：PCT/US2005/038021
申请日：2005-10-20
申请人： THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , KIM, Daniel H.
发明人： KIM, Daniel H.
IPC分类号： A61B17/56
摘要： Systems and devices for dynamically stabilizing the spine are provided. The systems include a superior component for attachment to a superior vertebra of a spinal motion segment and an inferior component for attachment to an inferior vertebral of a spinal motion segment. The interconnection between the two components enables the spinal motion segment to move in a manner that mimics the natural motion of the spinal motion segment. Methods are also provided for stabilizing the spine and for implanting the subject systems.

10. 发明申请

WO2020086110A1 APPARATUS AND METHOD FOR TRANSORAL MINIMALLY INVASIVE TREATMENT OF GASTROINTESTINAL DISEASES 审中-公开
公开(公告)号：WO2020086110A1
公开(公告)日：2020-04-30
申请号：PCT/US2019/018627
申请日：2019-02-19
申请人： KIM, Daniel H.
发明人： KIM, Daniel H.
IPC分类号： A61N1/36 , A61N1/05 , A61B18/14 , A61N5/06
摘要： Provided herein as a transoral minimally invasive method and a system thereof for the treatment of gastrointestinal diseases and/or obesity, which at least partially encircles a part of the gastrointestinal tract, such as esophagus of the patient by advancing an elongated deformable portion of a neurostimulator assembly endoluminally to the subfascial area from the outer wall of the esophagus and introducing the elongated deformable portion subfascially in the subfascial area, whereby at least one part of the encircled esophagus will be modulated using a modulator.

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