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1. 发明申请

WO2007075946A1 COMPOUNDS USEFUL IN CFTR ASSAYS AND METHODS THEREWITH 审中-公开
标题翻译： CFTR测定中使用的化合物及其方法
公开(公告)号：WO2007075946A1
公开(公告)日：2007-07-05
申请号：PCT/US2006/048900
申请日：2006-12-21
申请人： VERTEX PHARMACEUTICALS INCORPORATED , SINGH, Ashvani , VAN GOOR, Fredrick , WORLEY III, Jennings, Franklin , KNAPP, Thomas
发明人： SINGH, Ashvani , VAN GOOR, Fredrick , WORLEY III, Jennings, Franklin , KNAPP, Thomas
IPC分类号： G01N33/52 , C07K14/47 , C07D215/00 , C07D471/00
CPC分类号： G01N33/5032 , G01N33/5008 , G01N33/5044 , G01N33/5088 , G01N33/6872 , G01N2800/382
摘要： The present invention relates to compounds useful in CFTR assays. The present invention also relates to compounds useful in monitoring CFTR activity in therapies for CFTR- mediated diseases. The present invention also provides an assay for use in measuring CFTR correction.
摘要翻译：本发明涉及可用于CFTR测定的化合物。本发明还涉及可用于监测CFTR介导的疾病治疗中的CFTR活性的化合物。本发明还提供了用于测量CFTR校正的测定法。

2. 发明公开

EP1974212A1 COMPOUNDS USEFUL IN CFTR ASSAYS AND METHODS THEREWITH 审中-公开
标题翻译：在CFTR测试安排合适的化合物及其方法
公开(公告)号：EP1974212A1
公开(公告)日：2008-10-01
申请号：EP06845972.6
申请日：2006-12-21
申请人： VERTEX PHARMACEUTICALS INCORPORATED
发明人： SINGH, Ashvani , VAN GOOR, Fredrick , WORLEY III, Jennings Franklin , KNAPP, Thomas
IPC分类号： G01N33/52 , C07K14/47 , C07D215/00 , C07D471/00
CPC分类号： G01N33/5032 , G01N33/5008 , G01N33/5044 , G01N33/5088 , G01N33/6872 , G01N2800/382
摘要： The present invention relates to compounds useful in CFTR assays. The present invention also relates to compounds useful in monitoring CFTR activity in therapies for CFTR- mediated diseases. The present invention also provides an assay for use in measuring CFTR correction.

3. 发明申请

WO2008045682A1 SHAPE MEMORY FILAMENT FOR SUTURE MANAGEMENT 审中-公开
标题翻译：形状记忆管理用于管理
公开(公告)号：WO2008045682A1
公开(公告)日：2008-04-17
申请号：PCT/US2007/079549
申请日：2007-09-26
申请人： KNAPP, Thomas
发明人： KNAPP, Thomas
IPC分类号： A61B17/04
CPC分类号： A61B17/3401 , A61B17/0485 , A61B2017/00867
摘要： A member of a rigid flexible elastic material, the member including a body portion and an aperture portion with the member adapted for delivery through an axial longitudinal channel of a percutaneous delivery subsystem, the aperture portion including an expanded mode having a lateral dimension greater than an inner diameter of the channel when the aperture portion extends outside the channel and a collapsed mode wherein the lateral dimension is not greater than the inner diameter of the channel when the aperture portion is within the channel, the channel including a first axial opening and a second axial opening with the aperture portion transitioning from the expanded mode to the collapsed mode when inserted into the openings and the aperture transitioning from the collapsed mode to the expanded mode when exiting from the openings.
摘要翻译：刚性柔性弹性材料的构件，所述构件包括主体部分和开口部分，所述构件适于通过经皮递送子系统的轴向纵向通道输送，所述孔部分包括具有大于当所述开口部分延伸到所述通道外部时所述通道的内径和所述折叠模式，其中当所述开口部分在所述通道内时所述横向尺寸不大于所述通道的内径，所述通道包括第一轴向开口和第二轴向开口轴向开口，当插入到开口中时孔径部分从扩张模式转换到折叠模式，并且当从开口离开时，孔从折叠模式转变到扩张模式。

4. 发明申请

WO2011023294A1 VERFAHREN ZUR VERARBEITUNG EINES EINEN ANALOG BESTIMMTEN WERT FÜR AUSGANGSSTROM EINES UMRICHTERS DARSTELLENDEN MESSWERTSIGNALS UND VORRICHTUNG ZUR DURCHFÜHRUNG DES VERFAHRENS 审中-公开
标题翻译：方法处理特定的模拟值的电力输出驱动器的进行读出信号和设备用于实施过程
公开(公告)号：WO2011023294A1
公开(公告)日：2011-03-03
申请号：PCT/EP2010/004903
申请日：2010-08-11
申请人： SEW-EURODRIVE GMBH & CO. KG , KNAPP, Thomas , KOLLAR, Hans Jürgen , NEUMAYER, Ulrich , HAMMEL, Wolfgang
发明人： KNAPP, Thomas , KOLLAR, Hans Jürgen , NEUMAYER, Ulrich , HAMMEL, Wolfgang
IPC分类号： H03M3/02
CPC分类号： H03M3/462 , H03M1/645
摘要： Verfahren zur Verarbeitung eines einen analog bestimmten Wert für Ausgangsstrom eines Umrichters darstellenden Messwertsignals und Vorrichtung zur Durchführung des Verfahrens, wobei die von einem Sensor, insbesondere umfassend einen Shunt-Widerstand, erfassten Messwertsignale einem jeweiligen Verarbeitungskanal zugeführt werden, der zumindest einen Delta-Sigma-Modulator aufweist.
摘要翻译：一种用于处理用于逆变器的输出电流的一个模拟特定值用于执行该方法执行测量信号和设备的方法，所述测量值的信号，特别是包括由传感器检测的分流电阻器，被提供给相应的处理通道，所述至少一个Δ-Σ调制器有。

5. 发明申请

WO2008045683A1 SHAPE MEMORY FILAMENT FOR SUTURE MANAGEMENT 审中-公开
标题翻译：用于缝合管理的形状记忆细丝
公开(公告)号：WO2008045683A1
公开(公告)日：2008-04-17
申请号：PCT/US2007/079554
申请日：2007-09-26
申请人： KNAPP, Thomas , UIHLEIN, Bernhard , THOMPSON, Stanley , COONAHAN, Timothy , TAYLOR, Jon
发明人： KNAPP, Thomas , UIHLEIN, Bernhard , THOMPSON, Stanley , COONAHAN, Timothy , TAYLOR, Jon
IPC分类号： A61B17/24
CPC分类号： A61B17/0485 , A61B17/0401 , A61B17/06066 , A61B17/06166 , A61B2017/00867 , A61B2017/061
摘要： A member of a rigid flexible elastic material, the member including a body portion and an aperture portion with the member adapted for delivery through an axial longitudinal channel of a percutaneous delivery subsystem, the aperture portion including an expanded mode having a lateral dimension greater than an inner diameter of the channel when the aperture portion extends outside the channel and a collapsed mode wherein the lateral dimension is not greater than the inner diameter of the channel when the aperture portion is within the channel, the channel including a first axial opening and a second axial opening with the aperture portion transitioning from the expanded mode to the collapsed mode when inserted into the openings and the aperture transitioning from the collapsed mode to the expanded mode when exiting from the openings.
摘要翻译：刚性柔性弹性材料的构件，所述构件包括主体部分和孔部分，所述构件适于通过经皮递送子系统的轴向纵向通道输送，所述孔部分包括膨胀部分模式，当孔口部分延伸到通道外时具有大于通道内径的横向尺寸;以及折叠模式，其中当孔口部分在通道内时，横向尺寸不大于通道的内径，通道包括第一轴向开口和第二轴向开口，当孔口部分插入开口中时从扩张模式转变到收缩模式，并且孔口在从开口离开时从收缩模式过渡到扩张模式。

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