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1. 发明申请

WO2023079455A1 INTEGRATED PROCESS FOR THE PRODUCTION OF POLYHYDROXYALKANOATES AND BIOETHANOL FROM LIGNOCELLULOSE HYDROLYZATE 审中-公开
公开(公告)号：WO2023079455A1
公开(公告)日：2023-05-11
申请号：PCT/IB2022/060557
申请日：2022-11-02
申请人： VERSALIS S.P.A.
发明人： RODIGHIERO, Valentina , ERCOLE, Alessia , RIVA, Daniele , DEL SEPPIA, Alessandro , PRANDO, Tommaso , FRATTINI, Alessandra
IPC分类号： C12P7/625 , C12P7/10 , C12P7/14 , C12R1/05 , C12R1/07 , C12R1/38 , C12R1/85
摘要： Integrated process for the production of polyhydroxyalkanoates (PHAs) and bioethanol from lignocellulosic hydrolyzate comprising the following steps: (a) feeding at least a part of said lignocellulosic hydrolyzate to a first fermentation device in the presence of at least one microorganism capable of using sugars with six carbon atoms (C6) and organic acids, obtaining a first fermentation broth; (b) subjecting the first fermentation broth obtained in said step (a) to separation obtaining an aqueous suspension of cellular biomass comprising at least one polyhydroxyalkanoate (PHA) and an aqueous phase comprising sugars with five carbon atoms (C5) in a quantity greater than or equal to 10 g/L, preferably between 12 g/L and 100 g/L; (c) optionally, feeding at least a part of the aqueous phase obtained in said step (b), to a second fermentation device in the presence of at least one microorganism capable of using both sugars with five carbon atoms (C5) and sugars with six carbon atoms (C6), obtaining a second fermentation broth (inoculum); (d) feeding at least a part of the aqueous phase obtained in said step (b) and, optionally, the second fermentation broth (inoculum) obtained in said step (c) and/or at least a part of said lignocellulosic hydrolyzate, to a third fermentation device in the presence of at least one microorganism capable of using both sugars with five carbon atoms (C5) and sugars with six carbon atoms (C6), obtaining a third fermentation broth; (e) subjecting said third fermentation broth to separation obtaining bioethanol. The aforementioned polyhydroxyalkanoates (PHAs) can be advantageously used in various applications, in particular in the medical, pharmacological, agricultural, engineering and food fields. The aforementioned bioethanol can be advantageously used as it is, or mixed with fossil fuels, for automotive purposes, or, suitably purified, in the production of biochemicals (for example, disinfectants).

2. 发明申请

WO2019016703A1 VARIANT OF OLEAGINOUS YEAST AND ITS USE FOR THE PRODUCTION OF LIPIDS 审中-公开
公开(公告)号：WO2019016703A1
公开(公告)日：2019-01-24
申请号：PCT/IB2018/055301
申请日：2018-07-17
申请人： VERSALIS S.P.A. , UNIVERSITÀ DEGLI STUDI DI MILANO
发明人： RODIGHIERO, Valentina , FRANZOSI, Giuliana , COMPAGNO, Concetta , CAPUSONI, Claudia
IPC分类号： C12N1/16 , C12P7/64 , C12R1/645
摘要： The present invention relates to a variant of oleaginous yeast of the species Trichosporon oleaginosus characterized by mutations affecting cell wall synthesis that change the morphology thereof with respect to the wild-type strain of the same species. In particular, thanks to said mutations, cell aggregates are formed which, with respect to the wild-type strain of the same species, lower the viscosity of the culture broth, are more easily separable therefrom and thus make their recovery easier. Said variant of oleaginous yeast of the species Trichosporon oleaginosus is also characterized by yields of oleaginous cellular biomass and intracellular accumulation of lipids that are similar or even higher than those of the wild-type strain. Further, the present invention relates to a process for the production of lipids through said variant of oleaginous yeast of the species Trichosporon oleaginosus. The lipids thus obtained can be advantageously used as synthesis intermediates, particularly in the so-called "green chemistry" sector, or in the production of biofuels such as, for example, "biodiesel" or "green diesel", which can be used as such, or mixed with other fuels for transportation.

4. 发明公开

EP3655521A1 VARIANT OF OLEAGINOUS YEAST AND ITS USE FOR THE PRODUCTION OF LIPIDS 有权
公开(公告)号：EP3655521A1
公开(公告)日：2020-05-27
申请号：EP18755320.1
申请日：2018-07-17
申请人： Versalis S.p.A.
发明人： RODIGHIERO, Valentina , FRANZOSI, Giuliana , COMPAGNO, Concetta , CAPUSONI, Claudia
IPC分类号： C12N1/16 , C12P7/64 , C12R1/645

5. 发明公开

EP4444857A1 PROCESS FOR HYDRATING YEASTS IN DEHYDRATED FORM 审中-公开
公开(公告)号：EP4444857A1
公开(公告)日：2024-10-16
申请号：EP22822227.9
申请日：2022-12-06
申请人： Versalis S.p.A.
发明人： RODIGHIERO, Valentina , GASTALDO, Elena , OTTONELLO, Piero , DEL SEPPIA, Alessandro , PRANDO, Tommaso , FRATTINI, Alessandra
IPC分类号： C12N1/16 , C12N1/22 , C12P7/10 , C12N1/18
CPC分类号： C12P7/10 , C12N1/22 , C12N1/18 , Y02E50/10

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