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1. 发明申请

WO2008095033A3 ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 审中-公开
标题翻译：用于治疗细胞凋亡的酶，编码其核酸的酶及其制备和使用它们的方法
公开(公告)号：WO2008095033A3
公开(公告)日：2008-09-18
申请号：PCT/US2008052517
申请日：2008-01-30
申请人： VERENIUM CORP , SYNGENTA PARTICIPATIONS AG , CHANG CATHY , STEGE JUSTIN T , ABOUSHADI NAHLA , DJORDJEVIC GORDANA , BURKE ELLEN , LUGINBUHL PETER , DYCAICO MARK , RICHARDSON TOBY , POLAND JOHN , HEFNER YING , MILES STACY MARIE
发明人： STEGE JUSTIN T , ABOUSHADI NAHLA , DJORDJEVIC GORDANA , BURKE ELLEN , LUGINBUHL PETER , DYCAICO MARK , RICHARDSON TOBY , POLAND JOHN , HEFNER YING , MILES STACY MARIE
IPC分类号： C07K5/00 , A61K48/00 , C12N9/00
CPC分类号： C12P19/14 , C12N9/2437 , C12N9/2445 , C12P7/04 , C12P19/02 , C12Y302/01021 , Y02E50/16 , Y02E50/17 , Y02E50/343
摘要： The invention provides polypeptides having a lignocellulolytic activity, e.g., a glycosyl hydrolase, a cellulase, an endoglucanase, a cellobiohydrolase, a beta- glucosidase, a xylanase, a mannanse, a xylosidase (e.g., a ß- xylosidase), an arabinofuranosidase, and/or a glucose oxidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides that can enzymatically process (hydrolyze) sugarcane bagasse, i.e., for sugarcane bagasse degradation, or for biomass processing, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one embodiment, the invention provides thermostable and thermotolerant forms of polypeptides of the invention. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts; for example, the invention provides a multi-enzyme system that can hydrolyze polysaccharides in a bagasse component of sugarcane processed in sugar mills. The invention provides enzymes for the bioconversion of lignocellulosic residues into fermentable sugars; and these sugars can be used as a chemical feedstock for the production of ethanol and fuels, including biofuels such as bioethanol, biopropanol, biobutanol and biodiesels.
摘要翻译：本发明提供具有木质纤维素分解活性的多肽，例如糖基水解酶，纤维素酶，内切葡聚糖酶，纤维二糖水解酶，β-葡糖苷酶，木聚糖酶，甘露聚糖，木糖苷酶（例如β-木糖苷酶），阿拉伯呋喃糖苷酶和 /或葡萄糖氧化酶活性，编码这些多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。一方面，本发明提供了可以酶促加工（水解）甘蔗渣，即甘蔗渣降解或用于生物量加工的多肽，以及编码这些酶的多核苷酸，以及制备和使用这些多核苷酸和多肽。在一个实施方案中，本发明提供本发明的多肽的耐热性和耐热性形式。本发明的多肽可用于各种药物，农业和工业环境; 例如，本发明提供了一种可以在糖厂加工的甘蔗的蔗渣组分中水解多糖的多酶体系。本发明提供用于将木质纤维素残基生物转化成可发酵糖的酶; 并且这些糖可以用作生产乙醇和燃料的化学原料，包括生物燃料如生物乙醇，生物丙醇，生物丁醇和生物柴油。

2. 发明申请

WO2008095033A8 ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 审中-公开
标题翻译：用于治疗细胞凋亡的酶，编码其核酸的酶及其制备和使用它们的方法
公开(公告)号：WO2008095033A8
公开(公告)日：2009-09-03
申请号：PCT/US2008052517
申请日：2008-01-30
申请人： VERENIUM CORP , SYNGENTA PARTICIPATIONS AG , STEGE JUSTIN T , CHANG CATHY , ABOUSHADI NAHLA , DJORDJEVIC GORDANA , BURKE ELLEN , LUGINBUHL PETER , DYCAICO MARK , RICHARDSON TOBY , POLAND JOHN , HEFNER YING , MILES STACY MARIE
发明人： STEGE JUSTIN T , CHANG CATHY , ABOUSHADI NAHLA , DJORDJEVIC GORDANA , BURKE ELLEN , LUGINBUHL PETER , DYCAICO MARK , RICHARDSON TOBY , POLAND JOHN , HEFNER YING , MILES STACY MARIE
IPC分类号： C07K5/00 , A61K48/00 , C12N9/00
CPC分类号： C12P19/14 , C12N9/2437 , C12N9/2445 , C12P7/04 , C12P19/02 , C12Y302/01021 , Y02E50/16 , Y02E50/17 , Y02E50/343
摘要： The invention provides polypeptides having a lignocellulolytic activity, e.g., a glycosyl hydrolase, a cellulase, an endoglucanase, a cellobiohydrolase, a beta- glucosidase, a xylanase, a mannanse, a xylosidase (e.g., a ß- xylosidase), an arabinofuranosidase, and/or a glucose oxidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides that can enzymatically process (hydrolyze) sugarcane bagasse, i.e., for sugarcane bagasse degradation, or for biomass processing, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one embodiment, the invention provides thermostable and thermotolerant forms of polypeptides of the invention. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts; for example, the invention provides a multi-enzyme system that can hydrolyze polysaccharides in a bagasse component of sugarcane processed in sugar mills. The invention provides enzymes for the bioconversion of lignocellulosic residues into fermentable sugars; and these sugars can be used as a chemical feedstock for the production of ethanol and fuels, including biofuels such as bioethanol, biopropanol, biobutanol and biodiesels.
摘要翻译：本发明提供具有木质纤维素分解活性的多肽，例如糖基水解酶，纤维素酶，内切葡聚糖酶，纤维二糖水解酶，β-葡糖苷酶，木聚糖酶，甘露聚糖，木糖苷酶（例如β-木糖苷酶），阿拉伯呋喃糖苷酶和 /或葡萄糖氧化酶活性，编码这些多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。一方面，本发明提供了可以酶促加工（水解）甘蔗渣，即甘蔗渣降解或用于生物量加工的多肽，以及编码这些酶的多核苷酸，以及制备和使用这些多核苷酸和多肽。在一个实施方案中，本发明提供本发明的多肽的耐热性和耐热性形式。本发明的多肽可用于各种药物，农业和工业环境; 例如，本发明提供了一种可以在糖厂加工的甘蔗的蔗渣组分中水解多糖的多酶体系。本发明提供用于将木质纤维素残基生物转化成可发酵糖的酶; 并且这些糖可以用作生产乙醇和燃料的化学原料，包括生物燃料如生物乙醇，生物丙醇，生物丁醇和生物柴油。

3. 发明专利

JP2013176393A Enzyme for treatment of lignocellulosics, nucleic acid encoding the same, and method for making and using the same 审中-公开
标题翻译：用于处理纤维素的酶，编码其的核酸及其制备和使用方法
公开(公告)号：JP2013176393A
公开(公告)日：2013-09-09
申请号：JP2013118903
申请日：2013-06-05
申请人： Verenium Corp , ヴェレニウムコーポレイション , Syngenta Participations Ag , シンジェンタパーティシペーションズアーゲー
发明人： STEGE JUSTIN T , CHANG CATHY , ABOUSHADI NAHLA , DJORDJEVIC GORDANA , BURKE ELLEN , LUGINBUHL PETER , DYCAICO MARK , RICHARDSON TOBY , POLAND JOHN , HEFNER YING , MILES STACY MARIE
IPC分类号： C12N15/09 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/26 , C12N9/42 , C12P19/00 , C13K1/02 , C13K13/00
CPC分类号： C12P19/14 , C12N9/2437 , C12N9/2445 , C12P7/04 , C12P19/02 , C12Y302/01021 , Y02E50/16 , Y02E50/17 , Y02E50/343
摘要： PROBLEM TO BE SOLVED: To provide polypeptides having a lignocellulolytic activity, polynucleotides encoding these polypeptides, and methods for making and using these polynucleotides and polypeptides.SOLUTION: There are disclosed isolated, synthesized or recombinant nucleic acids containing nucleic acid sequences (polynucleotides) encoding a polypeptide having at least 80% of sequence identity (homology) to SEQ ID NO: 33 and a lignocellulosic activity, nucleic acid sequences encoding an enzymatically active fragment of the polypeptide, or nucleic acid sequences encoding a polypeptide capable of forming an antibody specifically binding to SEQ ID NO: 34 and/or its fragment.
摘要翻译：要解决的问题：提供具有木质纤维素分解活性的多肽，编码这些多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。解决方案：公开了分离的，合成的或重组的含有核酸序列（多核苷酸）与SEQ ID NO：33具有至少80％的序列同一性（同源性）和木质纤维素活性的多肽，编码多肽酶促活性片段的核酸序列，或编码能够形成特异性结合 SEQ ID NO：34和/或其片段。

4. 发明公开

EP2074136A4 ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 审中-公开
标题翻译：酶处理木质纤维素，用于编码这些AND METHOD FOR生产和使用核酸
公开(公告)号：EP2074136A4
公开(公告)日：2012-11-07
申请号：EP08728602
申请日：2008-01-30
申请人： VERENIUM CORP , SYNGENTA PARTICIPATIONS AG
发明人： STEGE JUSTIN T , ABOUSHADI NAHLA , DJORDJEVIC GORDANA , BURKE ELLEN , LUGINBUHL PETER , DYCAICO MARK , RICHARDSON TOBY , POLAND JOHN , HEFNER YING , MILES STACY MARIE , CHANG CATHY
IPC分类号： C07K5/00 , A61K48/00 , C12N9/00 , C12N9/42 , C12P7/10 , C12P19/02
CPC分类号： C12P19/14 , C12N9/2437 , C12N9/2445 , C12P7/04 , C12P19/02 , C12Y302/01021 , Y02E50/16 , Y02E50/17 , Y02E50/343
摘要： The invention provides polypeptides having a lignocellulolytic activity, e.g., a glycosyl hydrolase, a cellulase, an endoglucanase, a cellobiohydrolase, a beta-glucosidase, a xylanase, a mannanse, a xylosidase (e.g., a &bgr;-xylosidase), an arabinofuranosidase, and/or a glucose oxidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides that can enzymatically process (hydrolyze) sugarcane bagasse, i.e., for sugarcane bagasse degradation, or for biomass processing, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one embodiment, the invention provides thermostable and thermotolerant forms of polypeptides of the invention. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts; for example, the invention provides a multi-enzyme system that can hydrolyze polysaccharides in a bagasse component of sugarcane processed in sugar mills. The invention provides enzymes for the bioconversion of lignocellulosic residues into fermentable sugars; and these sugars can be used as a chemical feedstock for the production of ethanol and fuels, including biofuels such as bioethanol, biopropanol, biobutanol and biodiesels.

5. 发明专利

AR065544A1 ENZIMAS PARA EL TRATAMIENTO DE LIGNOCELULOSICOS ACIDOS NUCLEICOS QUE LAS CODIFICAN Y METODOS PARA PREPARARLAS Y USARLAS 未知
公开(公告)号：AR065544A1
公开(公告)日：2009-06-17
申请号：ARP080100387
申请日：2008-01-30
申请人： VERENIUM CORP , SYNGENTA PARTICIPATIONS AG
发明人： LUGINBUHL PETER , DYCAICO MARCK , STEGE JUSTIN T , RICHARDSON TOBY , POLAND JOHN , HEFNER YING , ABOUSHADI NAHLA , DJORDJEVIC GORDANA , CHANG CATHY , BURKE ELLEN
IPC分类号： C12N9/24 , C12N15/56 , C12N15/11 , C12N15/63 , C12N5/10 , C12N1/15 , C12N1/19 , C12N1/21 , A01K67/00 , A01H5/00 , A01H5/10 , C12Q1/68 , G01N33/50
摘要： La presente solicitud provee polipéptidos con actividad lignocelulítica, por ejemplo, una actividad de glicosilhidrolasa, celulasa, endoglucanasa, celobiohidrolasa, beta-glucosidase, xilanasa, mananasa, xilosidasa (por ejemplo alfa-xilosidasa),arabinofuranosidasa y/o glucosaoxidasa, polinucleotidos que codifican estos polipéptidos y métodos para preparar y usar estos polinucleotidos y polipéptidos. En un aspecto la presente solicitud provee polipéptidos capaces de procesar enzimáticamente(hidrolizar) bagazo de cana de azucar, por ejemplo, para la degradacion del bagazo de cana de azucar o para el procesamiento de biomasa, y polinucleotidos que codifican dichas enzimas, y la preparacion y el uso de estos polinucleotidos ypolipéptidos. En una forma de realizacion, se provee formas termoestables y termotolerantes de los polipéptidos de la presente. Dichos polipéptidos se pueden usar en diversos contextos farmacéuticos, agrícolas e industriales, por ejemplo, se proveeun sistema multienzimático capaz de hidrolizar los polisacáridos en un componente de bagazo de la cana de azucar procesada en molinos azucareros. La presente acta provee enzimas para la bioconversion de residuos lignocelulosicos en azucaresfermentables; y estos azucares se pueden usar como alimentacion química para la produccion de etanol y combustibles, incluso biocombustibles tales como bioetanol, biopropanol, biobutanol y biodiesel, Reivindicacion 1 Un ácido nucleico aislado,sintético o recombinante, que comprende (a) una secuencia de ácido nucleico (polinucleotido) que tiene al menos 50%, 51%, 52%. 53%, 54%, 55%, 56%, 57%, 58%, 59%, 60%, 61%, 62%, 63%, 64%, 65%, 66%, 67%, 68%, 69%, 70%, 71%, 72%, 73%, 74%, 75%, 76%,77%, 78%, 79%, 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, o más o completa (100%) identidad de secuencia con SEQ ID N°:1, SEQ ID N°:3, SEQ ID N°:5, SEQ ID N°:7, SEQ ID N°:9, SEQ ID N°:11, SEQID N°:13, SEQ ID N°:15, SEQ ID N°:17, SEQ ID N°:19, SEQ ID N°:21, SEQ ID N°:23, SEQ ID N°:25, SEQ ID N°:27, SEQ ID N°:29, SEQ ID N°:31, SEQ ID N°:33, SEQ ID N°:35, SEQ ID N°:37, SEQ ID N°:39, SEQ ID N°:41, SEQ ID N°:43, SEQ ID N°:45, SEQ ID N°:47,SEQ ID N°:49, SEQ ID N°:51, SEQ ID N°:53, SEQ ID N°:55, SEQ ID N°:57, SEQ ID N°:59, SEQ ID N°:61, SEQ ID N°:63, SEQ ID N°:65, SEQ ID N°:67, SEQ ID N°:69, SEQ ID N°:71, SEQ ID N°:73, SEQ ID N°:75. SEQ ID N°:77, SEQ ID N°:79, SEQ ID N°:81, SEQ IDN°:83, SEQ ID N°:85, SEQ ID N°:87, SEQ ID N°:89, SEQ ID N°:91, SEQ ID N°:93, SEQ ID N°:95, SEQ ID N°:97, SEQ ID N°:99. SEQ ID N°:101, SEQ ID N°:103, SEQ ID N°:105, SEQ ID N°:107, SEQ ID N°:109, SEQ ID N°:111, SEQ ID N°:113, SEQ ID N°:115, SEQ IDN°:117, SEQ ID N°:119, SEQ ID N°:121, SEQ ID N°:123, SEQ ID N°:125, SEQ ID N°:127, SEQ ID N°:129, SEQ ID N°:131, SEQ ID N°:133, SEQ ID N°:135, SEQ ID N°:137, SEQ ID N°:139, SEQ ID N°:141, SEQ ID N°:143, SEQ ID N°:145, SEQ ID N°:147, SEQ ID N°:149,SEQ ID N°:151, SEQ ID N°:153, SEQ ID N°:155, SEQ ID N°:157, SEQ ID N°:159, SEQ ID N°:161, SEQ ID N°:163, SEQ ID N°:165, SEQ ID N°:167. SEQ ID N°:169, SEQ ID N°:171, SEQ ID N°:173, SEQ ID N°:175, SEQ ID N°:177, SEQ ID N°:179, SEQ ID N°:181, SEQ IDN°:183, SEQ ID N°:185, SEQ ID N°:187, SEQ ID N°:189, SEQ ID N°:191, SEQ ID N°:193, SEQ ID N°:195, SEQ ID N°:197, SEQ ID N°:199, SEQ ID N°:201, SEQ ID N°:203, SEQ ID N°:205, SEQ ID N°:207, SEQ ID N°:209, SEQ ID N°:211, SEQ ID N°:213, SEQ ID N°:215,SEQ ID N°:217, SEQ ID N°:219, SEQ ID N°:221, SEQ ID N°:223, SEQ ID N°:225, SEQ ID N°:227, SEQ ID N°:229, SEQ ID N°:231, SEQ ID N°:233, SEQ ID N°:235, SEQ ID N°:237, SEQ ID N°:239, SEQ ID N°:241, SEQ ID N°:243, SEQ ID N°:245, SEQ ID N°:247, SEQ IDN°:249, SEQ ID N°:251, SEQ ID N°:253, SEQ ID N°:255, SEQ ID N°:257, SEQ ID N°:259, SEQ ID N°:261, SEQ ID N°:263, SEQ ID N°:265, SEQ ID N°:267, SEQ ID N°:269, SEQ ID N°:271, SEQ ID N°:273, SEQ ID N°:275, SEQ ID N°:277, SEQ ID N°:279, SEQ ID N°:281,SEQ ID N°:283, SEQ ID N°:285, SEQ ID N°:287, SEQ ID N°:289, SEQ ID N°:291, SEQ ID N°:293, SEQ ID N°:295, SEQ ID N°:297, SEQ ID N°:299, SEQ ID N°:301, SEQ ID N°:303, SEQ ID N°:305, SEQ ID N°:307, SEQ ID N°:309, SEQ ID N°:311, SEQ ID N°:313, SEQ IDN°:315, SEQ ID N°:317, SEQ ID N°:319, SEQ ID N°:321, SEQ ID N°:323, SEQ ID N°:325, SEQ ID N°:327, SEQ ID N°:329, SEQ ID N°:331, SEQ ID N°:333, SEQ ID N°:335, SEQ ID N°:337, SEQ ID N°:339, SEQ ID N°:341, SEQ ID N°:343, SEQ ID N°:345, SEQ ID N°;347,SEQ ID N°:349, SEQ ID N°:351, SEQ ID N°: 353, SEQ ID N°:355, SEQ ID N°:357, SEQ ID N°:359, SEQ ID N°:361, SEQ ID N°:363, SEQ ID N°:365, SEQ ID N°:367, SEQ ID N°:369, SEQ ID N°:370, SEQ ID N°:372, SEQ ID N°:373, SEQ ID N°:375, SEQ ID N°:376, SEQ IDN°:378, SEQ ID N°:379, SEQ ID N°:381, SEQ ID N°:382, SEQ ID N°:384, SEQ ID N°:385, SEQ ID N°:387, SEQ ID N°:388, SEQ ID N°:390, SEQ ID N°:391, SEQ ID N°:393, SEQ ID N°:394, SEQ ID N°:396, SEQ ID N°:397, SEQ ID N°:399, SEQ ID N°:400, SEQ ID N°:402,SEQ ID N°:403, SEQ ID N°:403, SEQ ID N°:405, SEQ ID N°:406, SEQ ID N°:408, SEQ ID N°:409, SEQ ID N°:411, SEQ ID N°:412, SEQ ID N°:414, SEQ ID N°:415, SEQ ID N°:417, SEQ ID N°:418, SEQ ID N°:420, SEQ ID N°:421, SEQ ID N°:423, SEQ ID N°:425, SEQ IDN°:427, SEQ ID N°:429, SEQ ID N°:431, SEQ ID N°:433, SEQ ID N°:435, SEQ ID N°:437, SEQ ID N°:439, SEQ ID N°:441, SEQ ID N°:443, SEQ ID N°:445, SEQ ID N°:447, SEQ ID N°:449, SEQ ID N°:451, SEQ ID N°:453, SEQ ID N°:455, SEQ ID N°:457, SEQ ID N°:459,SEQ ID N°:461, SEQ ID N°:463, SEQ ID N°:465, SEQ ID N°:467, SEQ ID N°:469, y/o SEQ ID N°:471, SEQ ID N°:480, SEQ ID N°:481, SEQ ID N°:482, SEQ ID N°:483, SEQ ID N°:484, SEQ ID N°:485, SEQ ID N°:486, SEQ ID N°:487, SEQ ID N°:488, y todas las otrassecuencias impares numeradas entre SEQ ID N°:489 y SEQ ID N°:700, SEQ ID N°:707, SEQ ID N°:708, SEQ ID N°:709, SEQ ID N°:710, SEQ ID N°:711, SEQ ID N°:712, SEQ ID N°:713, SEQ ID N°:714, SEQ ID N°:715, SEQ ID N°:716, SEQ ID N°:717, SEQ ID N°:718, y/oSEQ ID N°:720, sobre una region de al menos aproximadamente 20, 30, 40, 50, 75, 100, 150, 200, 250, 300, 350, 400, 450, 500, 550, 600, 650, 700, 750, 800, 850, 900, 1000, 1050, 1100, 1150, o más residuos, o la longitud total de un cADN, transcripto(mARN) o gen, en donde el ácido nucleico (polinucleotido) codifica un polipéptido que tiene una actividad lignocelulosica, o codifica un polipéptido o péptido capaz de generar un anticuerpo que específicamente se une con SEQ ID N°:2, SEQ ID N°:4,SEQ ID N°:6, SEQ ID N°:8, SEQ ID N°:10, SEQ ID N°:12, SEQ ID N°:14, SEQ ID N°:16, SEQ ID N°:18, SEQ ID N°:20, SEQ ID N°:22, SEQ ID N°:24, SEQ ID N°:26, SEQ ID N°:28, SEQ ID N°:30, SEQ ID N°:32, SEQ ID N°:34, SEQ ID N°:36, SEQ ID N°:38, SEQ ID N°:40,SEQ ID N°:42, SEQ ID N°:44, SEQ ID N°:46, SEQ ID N°:48, SEQ ID N°:50, SEQ ID N°:52, SEQ ID N°:54, SEQ ID N°:56, SEQ ID N°:58, SEQ ID N°:60, SEQ ID N°:62, SEQ ID N°:64, SEQ ID N°:66, SEQ ID N°:68, SEQ ID N°:70, SEQ ID N°:72, SEQ ID N°:74, SEQ IDN°:76, SEQ ID N°:78, SEQ ID N°:80, SEQ ID N°:82, SEQ ID N°:84, SEQ ID N°:86, SEQ ID N°:88, SEQ ID N°:90, SEQ ID N°:92, SEQ ID N°:94, SEQ ID N°:96, SEQ ID N°:98, SEQ ID N°:100, SEQ ID N°:102, SEQ ID N°:104, SEQ ID N°:106, SEQ ID N°:108, SEQ IDN°:110, SEQ ID N°:112, SEQ ID N°:114, SEQ ID N°:116, SEQ ID N°:118, SEQ ID N°:120, SEQ ID N°:122, SEQ ID N°:124, SEQ ID N°:126, SEQ ID N°:128, SEQ ID N°:130, SEQ ID N°:132, SEQ ID N°:134, SEQ ID N°:136, SEQ ID N°:138, SEQ ID N°:140, SEQ ID N°:142,SEQ ID N°:143, SEQ ID N°:146, SEQ ID N°:148, SEQ ID N°:150, SEQ ID N°:152, SEQ ID N°:154, SEQ ID N°:156, SEQ ID N°:158, SEQ ID N°:160, SEQ ID N°:162, SEQ ID N°:164, SEQ ID N°:166, SEQ ID N°:168, SEQ ID N°:170, SEQ ID N°:172, SEQ ID N°:174, SEQ IDN°:176, SEQ ID N°:178, SEQ ID N°:180, SEQ ID N°:182, SEQ ID N°:184, SEQ ID N°:186, SEQ ID N°:188, SEQ ID N°:190, SEQ ID N°:192, SEQ ID N°:194, SEQ ID N°:196, SEQ ID N°:198, SEQ ID N°:200, SEQ ID N°:202, SEQ ID N°:204, SEQ ID N°:206, SEQ ID N°:209,SEQ ID N°:210, SEQ ID N°:212, SEQ ID N°:214, SEQ ID N°:216, SEQ ID N°:218, SEQ ID N°:220, SEQ ID N°:222, SEQ ID N°:224, SEQ ID N°:226, SEQ ID N°:228, SEQ ID N°:230, SEQ ID N°:232, SEQ ID N°:234, SEQ ID N°:236, SEQ ID N°:238, SEQ ID N°:240, SEQ IDN°:242, SEQ ID N°:244, SEQ ID N°:246, SEQ ID N°:248, SEQ ID N°:250, SEQ ID N°:252, SEQ ID N°:254, SEQ ID N°:256, SEQ ID N°:258, SEQ ID N°:260, SEQ ID N°:262, SEQ ID N°:264, SEQ ID N°:266, SEQ ID N°:268, SEQ ID N°:270, SEQ ID N°:272, SEQ ID N°:274,SEQ ID N°:276, SEQ ID N°:278, SEQ ID N°:280, SEQ ID N°:282, SEQ ID N°:284, SEQ ID N°:286, SEQ ID N°:288, SEQ ID N°:290, SEQ ID N°:292, SEQ ID N°:294, SEQ ID N°:296, SEQ ID N°:298, SEQ ID N°:300, SEQ ID N°:302, SEQ ID N°:304, SEQ ID N°:306, SEQ IDN°:308, SEQ ID N°:310, SEQ ID N°:312, SEQ ID N°:314, SEQ ID N°:316, SEQ ID N°:318, SEQ ID N°:320, SEQ ID N°:322, SEQ ID N°:324, SEQ ID N°:326, SEQ ID N°:328, SEQ ID N°:330, SEQ ID N°:332, SEQ ID N°:334, SEQ ID N°:336, SEQ ID N°:338, SEQ ID N°:340,SEQ ID N°:342, SEQ ID N°: 344, SEQ ID N°:346, SEQ ID N°:348, SEQ ID N°:350, SEQ ID N°:352, SEQ ID N°:354, SEQ ID N°:356, SEQ ID N°:358, SEQ ID N°:360, SEQ ID N°:362, SEQ ID N°:364, SEQ ID N°:368, SEQ ID N°:371, SEQ ID N°:374, SEQ ID N°:377, SEQ IDN°:380, SEQ ID N°:383, SEQ ID N°:386, SEQ ID N°:389, SEQ ID N°:392, SEQ ID N°:395, SEQ ID N°:398, SEQ ID N°:401, SEQ ID N°:404, SEQ ID N°:407, SEQ ID N°:410, SEQ ID N°:413, SEQ ID N°:416, SEQ ID N°:419, SEQ ID N°:422, SEQ ID N°:424, SEQ ID N°:426,SEQ ID N°:428, SEQ ID N°:430, SEQ ID N°:432, SEQ ID N°:434, SEQ ID N°:436, SEQ ID N°:438, SEQ ID N°:440, SEQ ID N°:442, SEQ ID N°:444, SEQ ID N°:446, SEQ ID N°:448, SEQ ID N°:450, SEQ ID N°:452, SEQ ID N°:454, SEQ ID N°:456, SEQ ID N°:458, SEQ IDN°:460, SEQ ID N°:462, SEQ ID N°:464, SEQ ID N°:466, SEQ ID N°:468, SEQ ID N°:470 y/o SEQ ID N°:472, SEQ ID N°:473, SEQ ID N°:474, SEQ ID N°:475, SEQ ID N°:476, SEQ ID N°:477, SEQ ID N°:478, SEQ ID N°:479, y todos los numeros de secuencias entre SEQID N°:490 y SEQ ID N°:700, SEQ ID N°:719 y/o SEQ ID N°:721, y/o sus subsecuencias (fragmentos) enzimáticamente activas, en donde opcionalmente la actividad l

6. 发明专利

CA2674721C ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 未知
公开(公告)号：CA2674721C
公开(公告)日：2018-04-03
申请号：CA2674721
申请日：2008-01-30
申请人： VERENIUM CORP , SYNGENTA PARTICIPATIONS AG
发明人： STEGE JUSTIN T , ABOUSHADI NAHLA , DJORDJEVIC GORDANA , BURKE ELLEN , LUGINBUHL PETER , DYCAICO MARK , RICHARDSON TOBY , POLAND JOHN , HEFNER YING , MILES STACY MARIE , CHANG CATHY
IPC分类号： C12N15/56 , A01K67/027 , A01N63/02 , A01P1/00 , A21D8/04 , A23C9/12 , A23L2/66 , A61K38/47 , A62D3/02 , B09C1/10 , C02F3/00 , C07H21/00 , C07K5/00 , C07K16/40 , C07K19/00 , C10L1/04 , C11D3/386 , C11D7/42 , C12N9/00 , C12N9/10 , C12N9/24 , C12N15/11 , C12N15/54 , C12N15/67 , C12P1/00 , C12P7/02 , C12P7/10 , C12P19/00 , C12P19/34 , C12Q1/34 , C40B40/06 , C40B40/10 , C40B50/06 , D06M16/00 , D21H25/02 , G01N33/53 , G01N33/573 , G06F19/22
摘要： The invention provides polypeptides having a lignocellulolytic activity, e.g., a glycosyl hydrolase, a cellulase, an endoglucanase, a cellobiohydrolase, a beta- glucosidase, a xylanase, a mannanse, a xylosidase (e.g., a .beta.- xylosidase), an arabinofuranosidase, and/or a glucose oxidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides that can enzymatically process (hydrolyze) sugarcane bagasse, i.e., for sugarcane bagasse degradation, or for biomass processing, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one embodiment, the invention provides thermostable and thermotolerant forms of polypeptides of the invention. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts; for example, the invention provides a multi-enzyme system that can hydrolyze polysaccharides in a bagasse component of sugarcane processed in sugar mills. The invention provides enzymes for the bioconversion of lignocellulosic residues into fermentable sugars; and these sugars can be used as a chemical feedstock for the production of ethanol and fuels, including biofuels such as bioethanol, biopropanol, biobutanol and biodiesels.

7. 发明专利

CA2674721A1 ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS, NUCLEIC ACIDSENCODING THEM AND METHODS FOR MAKING AND USING THEM 未知
公开(公告)号：CA2674721A1
公开(公告)日：2008-08-07
申请号：CA2674721
申请日：2008-01-30
申请人： VERENIUM CORP , SYNGENTA PARTICIPATIONS AG
发明人： ABOUSHADI NAHLA , DJORDJEVIC GORDANA , BURKE ELLEN , STEGE JUSTIN T , DYCAICO MARK , LUGINBUHL PETER , POLAND JOHN , RICHARDSON TOBY , HEFNER YING , MILES STACY MARIE , CHANG CATHY
IPC分类号： C12N15/56 , A01H5/00 , A01K67/027 , A01N63/02 , A01P1/00 , A21D8/04 , A23C9/12 , A23K1/165 , A23L1/305 , A23L2/66 , A61K38/47 , A62D3/02 , B09C1/10 , C02F3/00 , C07H21/00 , C07K5/00 , C07K16/40 , C07K19/00 , C10L1/04 , C11D3/386 , C11D7/42 , C12N9/00 , C12N9/10 , C12N9/24 , C12N15/11 , C12N15/54 , C12N15/67 , C12P1/00 , C12P7/02 , C12P7/10 , C12P19/00 , C12P19/34 , C12Q1/34 , C12Q1/68 , C40B40/06 , C40B40/10 , C40B50/06 , D06M16/00 , D21H25/02 , G01N33/53 , G01N33/573 , G06F19/00
摘要： The invention provides polypeptides having a lignocellulolytic activity, e.g., a glycosyl hydrolase, a cellulase, an endoglucanase, a cellobiohydrola se, a beta- glucosidase, a xylanase, a mannanse, a xylosidase (e.g., a .beta .- xylosidase), an arabinofuranosidase, and/or a glucose oxidase activity, p olynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provide s polypeptides that can enzymatically process (hydrolyze) sugarcane bagasse, i.e., for sugarcane bagasse degradation, or for biomass processing, and pol ynucleotides encoding these enzymes, and making and using these polynucleoti des and polypeptides. In one embodiment, the invention provides thermostable and thermotolerant forms of polypeptides of the invention. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural a nd industrial contexts; for example, the invention provides a multi-enzyme s ystem that can hydrolyze polysaccharides in a bagasse component of sugarcane processed in sugar mills. The invention provides enzymes for the bioconvers ion of lignocellulosic residues into fermentable sugars; and these sugars ca n be used as a chemical feedstock for the production of ethanol and fuels, i ncluding biofuels such as bioethanol, biopropanol, biobutanol and biodiesels .

8. 发明专利

NZ578309A ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 未知
公开(公告)号：NZ578309A
公开(公告)日：2012-06-29
申请号：NZ57830908
申请日：2008-01-30
申请人： VERENIUM CORP , SYNGENTA PARTICIPATIONS AG
发明人： STEGE JUSTIN T , ABOUSHADI NAHLA , DJORDJEVIC GORDANA , BURKE ELLEN , LUGINBUHL PETER , DYCAICO MARK , RICHARDSON TOBY , POLAND JOHN , HEFNER YING , MILES STACY MARIE , CHANG CATHY
IPC分类号： C07K5/00 , A61K48/00 , C12N9/00
摘要： Disclosed are polypeptides having a lignocellulolytic activity, e.g., a glycosyl hydrolase, a cellulase, an endoglucanase, a cellobiohydrolase, a beta- glucosidase, a xylanase, a mannanse, a xylosidase (e.g., a â- xylosidase), an arabinofuranosidase, and/or a glucose oxidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides that can enzymatically process (hydrolyze) sugarcane bagasse, i.e., for sugarcane bagasse degradation, or for biomass processing, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one embodiment, the invention provides thermostable and thermotolerant forms of polypeptides of the invention. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts; for example, the invention provides a multi-enzyme system that can hydrolyze polysaccharides in a bagasse component of sugarcane processed in sugar mills. The invention provides enzymes for the bioconversion of lignocellulosic residues into fermentable sugars; and these sugars can be used as a chemical feedstock for the production of ethanol and fuels, including biofuels such as bioethanol, biopropanol, biobutanol and biodiesels.

9. 发明专利

ZA200904684B ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 未知
公开(公告)号：ZA200904684B
公开(公告)日：2011-10-26
申请号：ZA200904684
申请日：2009-07-03
申请人： VERENIUM CORP , SYNGENTA PARTICIPATIONS AG
发明人： STEGE JUSTIN , CHANG CATHY , ABOUSHADI NAHLA , DJORDJEVIC GORDANA , BURKE ELLEN , LUGINBUHL PETER , DYCAICO MARK , RICHARDSON TOBY , POLAND JOHN , HEFNER YING , MILES STACY MARIE
IPC分类号： C07K20060101 , A61K20060101 , C12N20060101
摘要： The invention provides polypeptides having a lignocellulolytic activity, e.g., a glycosyl hydrolase, a cellulase, an endoglucanase, a cellobiohydrolase, a beta-glucosidase, a xylanase, a mannanse, a xylosidase (e.g., a &bgr;-xylosidase), an arabinofuranosidase, and/or a glucose oxidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides that can enzymatically process (hydrolyze) sugarcane bagasse, i.e., for sugarcane bagasse degradation, or for biomass processing, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one embodiment, the invention provides thermostable and thermotolerant forms of polypeptides of the invention.

10. 发明专利

AU2008210495A1 Enzymes for the treatment of lignocellulosics, nucleic acids encoding them and methods for making and using them 未知
公开(公告)号：AU2008210495A1
公开(公告)日：2008-08-07
申请号：AU2008210495
申请日：2008-01-30
申请人： VERENIUM CORP , SYNGENTA PARTICIPATIONS AG
发明人： HEFNER YING , STEGE JUSTIN T , MILES STACY MARIE , POLAND JOHN , LUGINBUHL PETER , ABOUSHADI NAHLA , BURKE ELLEN , RICHARDSON TOBY , DYCAICO MARK , DJORDJEVIC GORDANA
IPC分类号： C07K5/00 , A61K48/00 , C12N9/00
摘要： The invention provides polypeptides having a lignocellulolytic activity, e.g., a glycosyl hydrolase, a cellulase, an endoglucanase, a cellobiohydrolase, a beta-glucosidase, a xylanase, a mannanse, a xylosidase (e.g., a &bgr;-xylosidase), an arabinofuranosidase, and/or a glucose oxidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides that can enzymatically process (hydrolyze) sugarcane bagasse, i.e., for sugarcane bagasse degradation, or for biomass processing, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one embodiment, the invention provides thermostable and thermotolerant forms of polypeptides of the invention.

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