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1. 发明授权

US4313950A Antireproductive tricyclic ortho-fused nitrogen containing compounds 失效
标题翻译：抗生素三环邻位稠合含氮化合物
公开(公告)号：US4313950A
公开(公告)日：1982-02-02
申请号：US230138
申请日：1981-01-30
申请人： Umberto Guzzi , Amedeo Omodei-Sale , Giulio Galliani
发明人： Umberto Guzzi , Amedeo Omodei-Sale , Giulio Galliani
IPC分类号： C07D217/24 , C07D223/16 , C07D471/04 , C07D487/04 , A61K31/47
CPC分类号： C07D223/16 , C07D217/24 , C07D471/04 , C07D487/04 , Y10S514/96
摘要： New tricyclic ortho-fused nitrogen containing compounds of the following formula: ##STR1## wherein R and R.sub.1 are independently selected from hydrogen, fluoro, chloro, bromo and (C.sub.1 -C.sub.4)alkoxy; A may be --CH.sub.2 --, --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- or --(CH.sub.2).sub.3 --; X represents a nitrogen atom or the group CH; and salts therewith of pharmaceutically acceptable acids.The compounds possess an outstanding antireproductive utility.
摘要翻译：新的具有下式的三环邻 - 稠合氮化合物：其中R和R 1独立地选自氢，氟，氯，溴和（C 1 -C 4）烷氧基; A可以是-CH 2 - ， - CH 2 -CH 2 - ， - CH = CH - 或 - （CH 2）3 - ; X表示氮原子或基团CH; 以及其与药学上可接受的酸的盐。该化合物具有突出的抗生素效用。

2. 发明授权

US4275066A Antireproductive tricyclic ortho-fused nitrogen containing compounds 失效
标题翻译：抗生素三环邻位稠合含氮化合物
公开(公告)号：US4275066A
公开(公告)日：1981-06-23
申请号：US87371
申请日：1979-10-23
申请人： Umberto Guzzi , Amedeo Omodei-Sale' , Giulio Galliani
发明人： Umberto Guzzi , Amedeo Omodei-Sale' , Giulio Galliani
IPC分类号： A61K31/41 , A61K31/415 , A61K31/47 , A61K31/55 , A61P33/02 , C07D217/24 , C07D223/16 , C07D471/04 , C07D487/04
CPC分类号： C07D223/16 , C07D217/24 , C07D471/04 , C07D487/04 , Y10S514/96
摘要： New tricyclic ortho-fused nitrogen containing compounds of the following formula: ##STR1## wherein R and R.sub.1 are independently selected from hydrogen, fluoro, chloro, bromo and (C.sub.1 -C.sub.4)alkoxy; A may be --CH.sub.2 --, --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- or --(CH.sub.2).sub.3 --; X represents a nitrogen atom or the group CH; and salts therewith of pharmaceutically acceptable acids.The compounds possess an outstanding antireproductive utility.
摘要翻译：新的具有下式的三环邻 - 稠合氮化合物：其中R和R 1独立地选自氢，氟，氯，溴和（C 1 -C 4）烷氧基; A可以是-CH 2 - ， - CH 2 -CH 2 - ， - CH = CH - 或 - （CH 2）3 - ; X表示氮原子或基团CH; 以及其与药学上可接受的酸的盐。该化合物具有突出的抗生素效用。

3. 发明授权

US4888350A New acyl-1H-1,2,4-triazole derivatives 失效
标题翻译：新的酰基-1H-1,2,4-三唑衍生物
公开(公告)号：US4888350A
公开(公告)日：1989-12-19
申请号：US915119
申请日：1986-10-03
申请人： Amedeo Omodei-Sale' , Pietro Consonni , Giulio Galliani
发明人： Amedeo Omodei-Sale' , Pietro Consonni , Giulio Galliani
IPC分类号： C07D233/54 , C07D249/08
CPC分类号： C07D233/64 , C07D233/54 , C07D249/08
摘要： New acyl -1H-1,2,4-triazole derivatives of the formula ##STR1## wherein R may be located on one of the two adjacent nitrogen atoms and may represent hydrogen; a group R.sub.5 -CO wherein R.sub.5 is selected from (C.sub.1-4)alkyl, (C.sub.2-4)alkenyl, (C.sub.2-4)alkynyl, phenyl, phenyl substituted by one to three groups independently selected from halo, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, trifluoromethyl, cyano, nitro, amino, di-(C.sub.1-4)alkylamino, (C.sub.2-4)acylamino and methylenedioxy, benzyl, cinnamyl, amino, (C.sub.1-4)alkylamino, di-(C.sub.1 -C.sub.4)alkylamino, phenylamino, phenylamino wherein the phenyl ring may be substituted by one to three groups independently selected from halo, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, trifluoromethyl, cyano, nitro, amino, di-(C.sub.1-4)alkylamino, (C.sub.2-4)acylamino and methylendioxy, halo(C.sub.1-4)alkyl, (C.sub.1-4)alkoxy and benzyloxy; a group R.sub.6 -SO.sub.2 wherein R.sub.6 may represent (C.sub.1-4)alkyl, phenyl, phenyl substituted by a radical selected from (C.sub.1-4)alkyl and (C.sub.1-4)alkoxy, or phenactyl;R.sub.1 is selected from hydrogen, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, allyloxy, propargyloxy, trifluormethyl, phenyl, halo and dimethylamino;R.sub.2 may represent the group ##STR2## wherein R.sub.7 is hydrogen or methyl and R.sub.8 is a (C.sub.1-4)alkyl radical, the group R.sub.5.sup.--CO or the group R.sub.6.sup.-- SO.sub.2 in which R.sub.5 and R.sub.6 are defined as above, or R.sub.7 and R.sub.8 taken together may represent a further bond between the carbon and oxygen atom;R.sub.3 and R.sub.4 are independently selected from hydrogen, halo, (C.sub.1-4)alkyl and (C.sub.1-4)alkoxy;R.sub.1 and R.sub.4 taken together may also repesent a methylenedioxy group; with the provison that, when R represents hydrogen, R.sub.2 must be the group ##STR3## in which R.sub.8 must be the group R.sub.6.sup.--SO.sub.2 wherein R.sub.6 is as above defined; and salts therewith of pharmaceutically acceptable acids. The compounds possess antireproductive utility.
摘要翻译：式Ⅰ的新的酰基-1H-1,2,4-三唑衍生物，其中R可以位于两个相邻的氮原子之一上并且可以代表氢; 其中R 5选自（C 1-4）烷基，（C 2-4）烯基，（C 2-4）炔基，苯基，被一至三个独立地选自卤素，（C 1-4）烷基，（C 1-4）烷氧基，三氟甲基，氰基，硝基，氨基，二 - （C 1-4）烷基氨基，（C 2-4）酰氨基和亚甲二氧基，苄基，肉桂基，氨基，（C 1-4）烷基氨基，（C 1 -C 4）烷基氨基，苯基氨基，苯基氨基，其中苯环可以被一至三个独立地选自卤素，（C 1-4）烷基，（C 1-4）烷氧基，三氟甲基，氰基，硝基，氨基，二 - （C 1-4）烷基氨基，（C 2-4）酰氨基和甲基二氧基，卤代（C 1-4）烷基，（C 1-4）烷氧基和苄氧基; 基团R6-SO2，其中R6可以表示（C1-4）烷基，苯基，被选自（C1-4）烷基和（C1-4）烷氧基的基团取代的苯基或苯甲酰基; R 1选自氢，（C 1-4）烷基，（C 1-4）烷氧基，烯丙氧基，炔丙氧基，三氟甲基，苯基，卤素和二甲基氨基; R 2可以表示基团，其中R 7是氢或甲基，R 8是（C 1-4）烷基，R 5 -CO或其中R 5和R 6如上所定义的基团R 6 -SO 2，或R 7和一起可以代表碳和氧原子之间的另一个键; R 3和R 4独立地选自氢，卤素，（C 1-4）烷基和（C 1-4）烷氧基; R 1和R 4一起也可以代替亚甲二氧基; 当R表示氢时，R2必须是其中R8必须是R6-SO2的基团，其中R6如上所定义; 以及其与药学上可接受的酸的盐。该化合物具有抗生素效用。

4. 发明授权

US4459302A Acyl-1H-1,2,4-triazole derivatives 失效
公开(公告)号：US4459302A
公开(公告)日：1984-07-10
申请号：US87375
申请日：1979-10-23
申请人： Amedeo Omodei-Sale , Pietro Consonni , Giulio Galliani
发明人： Amedeo Omodei-Sale , Pietro Consonni , Giulio Galliani
IPC分类号： A61K31/41 , C07D233/54 , C07D249/08 , C07D249/12 , C07D405/04
CPC分类号： C07D233/64 , C07D233/54 , C07D249/08 , Y10S514/841
摘要： New acyl-1H-1,2,4-triazole derivatives of the formula ##STR1## wherein R may be located on one of the two adjacent nitrogen atoms and may represent hydrogen; a group R.sub.5 -CO wherein R.sub.5 is selected from (C.sub.1-4)alkyl, (C.sub.2-4)alkenyl, (C.sub.2-4)alkynyl, phenyl, phenyl substituted by one to three groups independently selected from halo, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, trifluoromethyl, cyano, nitro, amino, di-(C.sub.1-4)alkylamino, (C.sub.2-4)acylamino and methylenedioxy, benzyl, cinnamyl, amino, (C.sub.1-4)alkylamino, di-(C.sub.1 -C.sub.4)alkylamino, phenylamino, phenylamino wherein the phenyl ring may be substituted by one to three groups independently selected from halo, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, trifluoromethyl, cyano, nitro, amino, di-(C.sub.1-4)alkylamino, (C.sub.2-4)acylamino and methylenedioxy, halo(C.sub.1-4)alkyl, (C.sub.1-4)alkoxy and benzyloxy;a group R.sub.6 -SO.sub.2 wherein R.sub.6 may represent (C.sub.1-4)alkyl, phenyl, phenyl substituted by a radical selected from (C.sub.1-4)alkyl and (C.sub.1-4)alkoxy, or phenacyl;R.sub.1 is selected from hydrogen, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, allyloxy, propargyloxy, trifluoromethyl, phenyl, halo and dimethylamino;R.sub.2 may represent a (C.sub.1-4)alkyl radical or the group ##STR2## wherein R.sub.7 is hydrogen or methyl and R.sub.8 is a (C.sub.1-4)alkyl radical, the group R.sub.5 -CO or the group R.sub.6 -SO.sub.2 in which R.sub.5 and R.sub.6 are defined as above, or R.sub.7 and R.sub.8 taken together may represent a further bond between the carbon and oxygen atom;R.sub.3 and R.sub.4 are independently selected from hydrogen, halo, (C.sub.1-4)alkyl and (C.sub.1-4)alkoxy;R.sub.1 and R.sub.4 taken together may also represent a methylenedioxy group; with the proviso that, when R represents hydrogen, R.sub.2 must be the group ##STR3## in which R.sub.8 must be the group R.sub.5 -CO or the group R.sub.6 -SO.sub.2 wherein R.sub.5 and R.sub.6 are as above defined;and salts therewith of pharmaceutically acceptable acids. The compounds possess antireproductive utility.

5. 发明授权

US4370336A 3,5-Disubstituted-1H-1,2,4-triazole derivatives as antifertility agents 失效
标题翻译： 3,5-二取代-1H-1,2,4-三唑衍生物作为抗菌剂
公开(公告)号：US4370336A
公开(公告)日：1983-01-25
申请号：US254729
申请日：1981-04-16
申请人： Amedeo Omodei-Sale , Pietro Consonni , Giulio Galliani , Leonard Lerner
发明人： Amedeo Omodei-Sale , Pietro Consonni , Giulio Galliani , Leonard Lerner
IPC分类号： C07D249/08 , A61K31/41
CPC分类号： C07D249/08
摘要： New 3,5-disubstituted-1H-1,2,4-triazoles of formula ##STR1## wherein: R is selected from hydrogen, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, allyloxy, propargyloxy, trifluoromethyl, phenyl, fluoro, chloro and dimethylamino;R.sub.1 represents a (C.sub.1-4)alkyl group;R.sub.2 is selected from hydrogen, fluoro, chloro, (C.sub.1-4)alkyl, methoxy and ethoxy;R.sub.3 is selected from hydrogen, fluoro, chloro, (C.sub.1-4)alkyl and (C.sub.1-4)alkoxy;R and R.sub.3 taken together represent a methylenedioxy group; with the proviso that, when simultaneously R, R.sub.2 and R.sub.3 represent hydrogen,cannot be methyl;with the further proviso that, when simultaneously R.sub.2 and one of R and R.sub.3 represent hydrogen, R.sub.1 and the other of R and R.sub.3 cannot simultaneously represent methyl;and salts therewith of pharmaceutically acceptable acids.The compounds possess anti-reproductive utility.
摘要翻译：新的式（I）的3,5-二取代-1H-1,2,4-三唑其中：R选自氢，（C 1-4）烷基，（C 1-4）烷氧基，烯丙氧基，炔丙氧基，三氟甲基，苯基，氟，氯和二甲基氨基; R1表示（C1-4）烷基; R 2选自氢，氟，氯，（C 1-4）烷基，甲氧基和乙氧基; R3选自氢，氟，氯，（C1-4）烷基和（C1-4）烷氧基; R和R3一起代表亚甲二氧基; 条件是当同时R，R 2和R 3表示氢时，不能是甲基; 进一步的条件是当R 2和R 3中的一个表示氢时，R 1和R 3和R 3中的另一个不能同时表示甲基; 以及其与药学上可接受的酸的盐。这些化合物具有抗生殖效用。

6. 发明授权

US4535090A 3,5-Diphenyl-1H-1,2,4-triazoles pharmaceutical compositions and uses 失效
标题翻译： 3,5-二苯基-1H-1,2,4-三唑类药物组合物及用途
公开(公告)号：US4535090A
公开(公告)日：1985-08-13
申请号：US434451
申请日：1982-10-15
申请人： Giulio Galliani , Amedeo Omodei-Sale , Pietro Consonni , Alessandro Assandri
发明人： Giulio Galliani , Amedeo Omodei-Sale , Pietro Consonni , Alessandro Assandri
IPC分类号： A61K9/08 , A61K9/107 , A61K31/41 , A61P11/00 , C07C243/38 , C07D249/08 , C07D249/10 , C07D405/04 , C07D405/10
CPC分类号： C07D249/08 , C07C243/38 , C07D405/04 , Y10S514/843
摘要： 3,5-diphenyl-1H-1,2,4-triazoles with contragestational activity of the following formula ##STR1## wherein R may be located on one or the other of the two adjacent nitrogen atoms and may represent hydrogen or a group R.sub.5 CO-- wherein R.sub.5 is an aliphatic saturated or unsaturated hydrocarbyl containing from 1 to 20 carbon atoms, R.sub.1, R.sub.2 and R.sub.3, each independently are selected from hydrogen, lower alkyl and lower alkoxy or R.sub.2 and R.sub.3 together may represent a methylenedioxy group, and R.sub.4 is an aliphatic saturated or unsaturated hydrocarbyl group of from 1 to 20 carbons, with the proviso that when R is hydrogen or an R.sub.5 CO-- group wherein R.sub.5 contains 4 or less carbon atoms, R.sub.4 must contain 5 or more carbons.These compounds have proven to be highly effective in terminating pregnancy in several animal species after a single parenteral injection.
摘要翻译：具有下式的映射活性的3,5-二苯基-1H-1,2,4-三唑：其中R可以位于两个相邻氮原子的一个或另一个上，并且可以表示氢或基团R 5 CO- 其中R 5是含有1至20个碳原子的脂族饱和或不饱和烃基，R 1，R 2和R 3各自独立地选自氢，低级烷基和低级烷氧基，或者R 2和R 3一起可表示亚甲二氧基，并且R 4是具有1至20个碳原子的脂肪族饱和或不饱和烃基，条件是当R是氢或R5含有4个或更少碳原子的R5CO-基时，R4必须含有5个或更多个碳。已经证明这些化合物在单次肠胃外注射后在几种动物物种中终止妊娠是非常有效的。

7. 发明授权

US4409388A 1,2,4-Triazole derivatives, and their use as antifertility agents 失效
标题翻译： 1,2,4-三唑衍生物及其作为抗生育剂的用途
公开(公告)号：US4409388A
公开(公告)日：1983-10-11
申请号：US87376
申请日：1979-10-23
申请人： Amedeo Omodei-Sale' , Pietro Consonni , Giulio Galliani
发明人： Amedeo Omodei-Sale' , Pietro Consonni , Giulio Galliani
IPC分类号： A61K31/41 , C07D249/08
CPC分类号： C07D249/08
摘要： Novel 1,2,4-triazole derivatives are described having the following formula ##STR1## wherein R represents hydrogen or methyl, R.sub.1 stands for hydrogen or (C.sub.1 -C.sub.4)alkyl, or R and R.sub.1 taken together may represent a further bond between the carbon atom and the oxygen atom, R.sub.2 and R.sub.4, each independently, represent hydrogen, chloro, fluoro, bromo, (C.sub.1 -C.sub.4)alkyl or (C.sub.1 -C.sub.4)alkoxy, R.sub.3 stands for (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy, allyloxy, propargyloxy, trifluoromethyl, phenyl, chloro, fluoro, bromo or dimethylamino or R.sub.3 and R.sub.4 taken together may represent a methylenedioxy group.Also described is a process for their manufacture.Use of the novel compounds as antireproductive agents and pharmaceutical compositions containing them as active ingredients are also claimed.
摘要翻译：描述了具有下列结构式的新的1,2,4-三唑衍生物：其中R代表氢或甲基，R1代表氢或（C1-C4）烷基，或者R和R1一起代表在碳原子和氧原子，R2和R4各自独立地代表氢，氯，氟，溴，（C1-C4）烷基或（C1-C4）烷氧基，R3代表（C1-C4）烷基，（C1- C4）烷氧基，烯丙氧基，炔丙氧基，三氟甲基，苯基，氯，氟，溴或二甲基氨基或R3和R4一起表示亚甲二氧基。还描述了其制造方法。还要求保护使用新化合物作为抗生素剂和含有它们作为活性成分的药物组合物。

8. 发明授权

US4379155A 3,5-Disubstituted-1H-1,2,4-triazole derivatives 失效
标题翻译： 3,5-二取代-1H-1,2,4-三唑衍生物
公开(公告)号：US4379155A
公开(公告)日：1983-04-05
申请号：US284033
申请日：1981-07-17
申请人： Amedeo Omodei-Sale , Pietro Consonni , Giulio Galliani , Leonard J. Lerner
发明人： Amedeo Omodei-Sale , Pietro Consonni , Giulio Galliani , Leonard J. Lerner
IPC分类号： C07D249/08 , A61K31/41
CPC分类号： C07D249/08
摘要： New 3,5-disubstituted 1H-1,2,4-triazoles of formula I ##STR1## wherein: R is selected from hydrogen, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, allyloxy, propargyloxy, trifluoromethyl, phenyl, fluoro, chloro and dimethylamino;R.sub.1 represents a (C.sub.1-4)alkyl group;R.sub.2 is selected from hydrogen, fluoro, chloro, (C.sub.1-4)alkyl, methoxy and ethoxy;R.sub.3 is selected from hydrogen, fluoro, chloro, (C.sub.1-4)alkyl and (C.sub.1-4)alkoxy;R and R.sub.3 taken together represent a methylenedioxy group; with the proviso that, when R, R.sub.2 and R.sub.3 simultaneously represent hydrogen, R.sub.1 cannot be methyl;with the further proviso that, when R.sub.2 and one of R and R.sub.3 simultaneously represent hydrogen, R.sub.1 and the other of R and R.sub.3 cannot simultaneously represent methyl; and with the still further proviso that compounds of formula I are excluded wherein R.sub.2 is hydrogen and one of R and R.sub.3 is simultaneously a 2-positioned alkyl group and the other of R and R.sub.3 is hydrogen; and salts thereof with pharmaceutically acceptable acids. The compounds possess anti-reproductive utility.
摘要翻译：新的式I的3,5-二取代的1H-1,2,4-三唑其中：R选自氢，（C 1-4）烷基，（C 1-4）烷氧基，烯丙氧基，炔丙氧基，三氟甲基，苯基，氟，氯和二甲基氨基; R1表示（C1-4）烷基; R 2选自氢，氟，氯，（C 1-4）烷基，甲氧基和乙氧基; R3选自氢，氟，氯，（C1-4）烷基和（C1-4）烷氧基; R和R3一起代表亚甲二氧基; 条件是当R，R 2和R 3同时表示氢时，R 1不能是甲基; 进一步的条件是当R 2和R 3中的一个同时表示氢时，R 1和R 3和R 3中的另一个不能同时代表甲基; 并且另外的条件是排除式I化合物，其中R 2是氢，R 3和R 3之一同时是2-位烷基，R和R 3中的另一个是氢; 和其盐与药学上可接受的酸。这些化合物具有抗生殖效用。

9. 发明授权

US4370337A 1,2,4-Triazole derivatives as antifertility agents and pharmaceutical compositions containing them 失效
标题翻译： 1,2,4-三唑衍生物作为抗生育剂和含有它们的药物组合物
公开(公告)号：US4370337A
公开(公告)日：1983-01-25
申请号：US283715
申请日：1980-07-16
申请人： Amedeo Omodei-Sale' , Pietro Consonni , Giulio Galliani
发明人： Amedeo Omodei-Sale' , Pietro Consonni , Giulio Galliani
IPC分类号： C07D249/08 , A61K31/41
CPC分类号： C07D249/08
摘要： Novel 1,2,4-triazole derivatives are described having the following formula ##STR1## wherein R represents hydrogen or methyl, R.sub.1 stands for hydrogen or (C.sub.1 -C.sub.4)alkyl, or R and R.sub.1 taken together may represent a further bond between the carbon atom and the oxygen atom, R.sub.2 and R.sub.4, each independently, represent hydrogen, chloro, fluoro, bromo, (C.sub.1 -C.sub.4)alkyl or (C.sub.1 -C.sub.4)alkoxy, R.sub.3 stands for (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy, allyloxy, propargyloxy, trifluoromethyl, phenyl, chloro, fluoro, bromo or dimethylamino or R.sub.3 and R.sub.4 taken together may represent a methylenedioxy group.Also described is a process for their manufacture. Use of the novel compounds as antireproductive agents and pharmaceutical compositions containing them as active ingredient are also claimed.
摘要翻译：描述了具有下列结构式的新的1,2,4-三唑衍生物：其中R代表氢或甲基，R1代表氢或（C1-C4）烷基，或者R和R1一起代表在碳原子和氧原子，R2和R4各自独立地代表氢，氯，氟，溴，（C1-C4）烷基或（C1-C4）烷氧基，R3代表（C1-C4）烷基，（C1- C4）烷氧基，烯丙氧基，炔丙氧基，三氟甲基，苯基，氯，氟，溴或二甲基氨基或R3和R4一起表示亚甲二氧基。还描述了其制造方法。还要求保护使用新化合物作为抗再生剂和含有它们作为活性成分的药物组合物。

10. 发明授权

US5204341A 1-arylsulphonyl-2-pyrrolidone derivatives, their preparation process and the new intermediates obtained, their use as medicaments and the pharmaceutical compositions containing them 失效
标题翻译： 1-ARYLSULPHONYL-2-吡咯烷酮衍生物，其制备方法和获得的新的中间体，它们作为药物和含有它们的药物组合物使用
公开(公告)号：US5204341A
公开(公告)日：1993-04-20
申请号：US805694
申请日：1991-12-11
申请人： Emilio Toja , Carla Bonetti , Fernando Barzaghi , Giulio Galliani
发明人： Emilio Toja , Carla Bonetti , Fernando Barzaghi , Giulio Galliani
IPC分类号： A61K31/40 , A61K31/4015 , A61P25/02 , C07C311/39 , C07C311/42 , C07D207/24 , C07D207/273 , C07D207/48 , C07D401/12 , C07F9/572
CPC分类号： C07D401/12 , C07C311/39 , C07D207/48 , C07F9/5725
摘要： 1-arylsulphonyl-2-pyrrolidone derivatives for treating spasmodic disorders in gastro-enterology, in gynaecology, in obstetrics, in urology; intermediates in the preparation of such products; methods for preparing such products and pharmaceutical preparations containing such products.
摘要翻译： 1-芳基磺酰基-2-吡咯烷酮衍生物，用于治疗胃肠学，妇科，妇产科，泌尿科的痉挛性疾病; 中间体在制备此类产品时; 制备此类产品的方法和含有此类产品的药物制剂。

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