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1. 发明申请

WO2009089103A1 METHODS FOR FERMENTATION OF XYLOSE AND HEXOSE SUGARS 审中-公开
标题翻译：用于发酵XYLOSE和HEXOSE糖的方法
公开(公告)号：WO2009089103A1
公开(公告)日：2009-07-16
申请号：PCT/US2009/030033
申请日：2009-01-02
申请人： UNIVERSITY OF TOLEDO , VARANASI, Sasidhar , RAO, Kripa , RELUE, Patricia, Ann , YUAN, Dawei
发明人： VARANASI, Sasidhar , RAO, Kripa , RELUE, Patricia, Ann , YUAN, Dawei
IPC分类号： C12N1/00
CPC分类号： C12M21/18 , C12M21/12 , C12N1/16 , C12N1/18 , C12N11/00 , C12N11/18 , C12P7/06 , C12P7/14 , Y02E50/17
摘要： Methods and systems for the isomerization and/or fermentation of xylose and hexose sugars are disclosed.
摘要翻译：公开了用于木糖和己糖的异构化和/或发酵的方法和系统。

2. 发明申请

WO2008112291A2 BIOMASS PRETREATMENT 审中-公开
标题翻译：生物量预处理
公开(公告)号：WO2008112291A2
公开(公告)日：2008-09-18
申请号：PCT/US2008/003357
申请日：2008-03-13
申请人： THE UNIVERSITY OF TOLEDO , VARANASI, Sasidhar , SCHALL, Constance, Ann , DADI, Anantharam, Prasad , ANDERSON, Jared , RAO, Kripa , PARIPATI, Praveen , KUMAR, Guneet
发明人： VARANASI, Sasidhar , SCHALL, Constance, Ann , DADI, Anantharam, Prasad , ANDERSON, Jared , RAO, Kripa , PARIPATI, Praveen , KUMAR, Guneet
IPC分类号： C12P19/20 , C12P19/14
CPC分类号： C12P19/14 , C12P7/10 , C12P19/02 , C12P2201/00 , Y02E50/16 , Y02E50/17 , Y02E50/30
摘要： A method for lignocellulose conversion to sugar with improvements in yield and rate of sugar production has been developed by using ionic liquid pretreatment. This new pretreatment strategy substantially improves the efficiency (in terms of yield and reaction rates) of saccharification of lignocellulosic biomass. Cellulose and hemicellulose, when hydrolyzed into their sugars, can be converted into ethanol fuel through well established fermentation technologies. These sugars also form the feedstocks for production of variety of chemicals and polymers. The complex structure of biomass requires proper pretreatment to enable efficient saccharification of cellulose and hemicellulose components to their constituent sugars. Current pretreatment approaches suffer from slow reaction rates of cellulose hydrolysis (by using the enzyme cellulase) and low yields.
摘要翻译：通过使用离子液体预处理已经开发了木糖纤维素转化成糖的方法，其产率和产糖率得到提高。这种新的预处理策略显着提高了木质纤维素生物质糖化的效率（产率和反应速率）。当水解成糖时，纤维素和半纤维素可通过成熟的发酵技术转化为乙醇燃料。这些糖也形成用于生产各种化学品和聚合物的原料。生物质的复杂结构需要适当的预处理，以使纤维素和半纤维素成分能有效地糖化成其组成的糖。目前的预处理方法受到纤维素水解反应速度慢（通过使用酶纤维素酶）和低产率的影响。

3. 发明申请

WO2011057293A1 LIQUID RECOVERY AND PURIFICATION IN BIOMASS PRETREATMENT PROCESS 审中-公开
标题翻译：液体回收和净化生物量预处理过程
公开(公告)号：WO2011057293A1
公开(公告)日：2011-05-12
申请号：PCT/US2010/056076
申请日：2010-11-09
申请人： THE UNIVERSITY OF TOLEDO , LIPSCOMB, Glenn , VARANASI, Sasidhar
发明人： LIPSCOMB, Glenn , VARANASI, Sasidhar
IPC分类号： D21C11/00
CPC分类号： D21C11/00
摘要： The invention includes a process for recovering the liquids used in pretreatment of biomass for production of biofuels and other biomass based products. Liquid recovery and purification minimizes waste production and enhances process profitability.
摘要翻译：本发明包括用于回收用于生物燃料预处理和生物燃料生产的其他生物质基产品的液体回收方法。液体回收和净化最大限度地减少了废物的产生并提高了工艺的盈利能力。

4. 发明申请

WO2011133536A1 ALDOSE-KETOSE TRANSFORMATION FOR SEPARATION AND/OR CHEMICAL CONVERSION OF C6 AND C5 SUGARS FROM BIOMASS MATERIALS 审中-公开
标题翻译：用于从生物质材料分离和/或化学转化C6和C5糖的ALDOSE-KETOSE转化
公开(公告)号：WO2011133536A1
公开(公告)日：2011-10-27
申请号：PCT/US2011/033030
申请日：2011-04-19
申请人： THE UNIVERSITY OF TOLEDO , VARANASI, Sasidhar , RELUE, Patricia , LI, Bin
发明人： VARANASI, Sasidhar , RELUE, Patricia , LI, Bin
IPC分类号： C08B1/00 , C08K5/07
CPC分类号： C07H3/02 , B01J19/00 , C07H1/06 , C07H1/08 , C12M25/18 , C12M47/10 , C12N9/92 , C12Y503/01005 , C13K13/007 , Y02E50/17
摘要： Systems for converting aldose sugars to ketose sugars and separating and/or concentrating these sugars using differences in the sugars' abilities to bind to specific affinity ligands are described.
摘要翻译：描述了使用醛结合特异性亲和配体的能力差异将醛糖转化为酮糖糖并分离和/或浓缩这些糖的系统。

5. 发明申请

WO2012064868A2 IONIC LIQUID RECOVERY AND PURIFICATION IN BIOMASS TREATMENT PROCESSES 审中-公开
标题翻译：离子液体回收和净化生物质处理工艺
公开(公告)号：WO2012064868A2
公开(公告)日：2012-05-18
申请号：PCT/US2011/060021
申请日：2011-11-09
申请人： SUGANIT SYSTEMS, INC. , THE UNIVERSITY OF TOLEDO , LIPSCOMB, Glenn , VARANASI, Sasidhar , PARIPATI, Praveen , DADI, Anantharam, P.
发明人： LIPSCOMB, Glenn , VARANASI, Sasidhar , PARIPATI, Praveen , DADI, Anantharam, P.
IPC分类号： C02F3/12
CPC分类号： B01D61/58 , B01D61/025 , B01D61/027 , B01D61/145 , B01D61/147 , B01D61/362 , B01D61/422 , Y02E50/16
摘要： The invention includes a process for recovering ionic liquids used in the treatment of biomass for production of biofuels and other biomass-based products. Ionic liquid recovery and purification minimizes waste production and enhances process profitability.
摘要翻译：本发明包括用于回收用于生物质处理生物燃料和其他基于生物质的产品的离子液体回收方法。离子液体回收和净化最大限度地减少了废物的产生并提高了工艺的盈利能力。

6. 发明申请

WO2015066287A1 METHODS FOR HIGH YIELD PRODUCTION OF FURANS FROM BIOMASS SUGARS AT MILD OPERATING CONDITIONS 审中-公开
标题翻译：在轻度操作条件下从生物质糖中富集产生呋喃的方法
公开(公告)号：WO2015066287A1
公开(公告)日：2015-05-07
申请号：PCT/US2014/063091
申请日：2014-10-30
申请人： THE UNIVERSITY OF TOLEDO
发明人： ALIPOUR, Siamak , LI, Bin , VARANASI, Sasidhar , RELUE, Patricia , VIAMAJALA, Sridhar
IPC分类号： C07D307/50
CPC分类号： C12P17/04 , C07D307/50
摘要： Facile methods for high-yield furfural and HMF production from biomass sugars are described. The methods generally involve converting the biomass sugars in high yield to their ketose isomers, resulting in furan production under low temperature and pressure conditions with efficient recycling of the process streams.
摘要翻译：描述了用于从生物质糖生产高产率糠醛和HMF的简便方法。这些方法通常包括将高产量的生物质糖转化为它们的酮糖异构体，从而在低温和高压条件下生产呋喃，并有效循环工艺流。

7. 发明申请

WO2015031762A1 ENZYMATIC DIGESTION OF MICROALGAL BIOMASS FOR LIPID, SUGAR, AND PROTEIN RECOVERY 审中-公开
标题翻译：用于脂肪，糖和蛋白质恢复的微生物生物量的酶消化
公开(公告)号：WO2015031762A1
公开(公告)日：2015-03-05
申请号：PCT/US2014/053421
申请日：2014-08-29
申请人： THE UNIVERSITY OF TOLEDO
发明人： VADLAMANI, Agasteswar , TAYLOR, David, J. , RELUE, Patricia , VIAMAJALA, Sridhar , SHAO, Heng , VARANASI, Sasidhar
IPC分类号： C12P1/00
CPC分类号： C12P7/46 , C12P7/6463 , C12P19/02 , C12P19/14 , C12P21/06 , C12P2203/00 , C12Y302/01001 , C12Y304/21014
摘要： Methods for the recovery of lipids, sugars, and proteins from microbial biomass by enzymatic digestion are disclosed. The methods involve treating microalgae with a fungal acid protease, or with a mixture of at least one protease and at least one amylase.
摘要翻译：公开了通过酶消化从微生物生物质中回收脂质，糖和蛋白质的方法。该方法包括用真菌酸性蛋白酶或至少一种蛋白酶与至少一种淀粉酶的混合物处理微藻。

8. 发明申请

WO2015200200A1 CROSS METATHESIS APPROACH TO C11-C13 FATTY-CHAIN AMINO ESTERS FORM OLEIC ACID DERIVATIVES 审中-公开
标题翻译： C11-C13脂肪链烷基酯衍生物的交联方法
公开(公告)号：WO2015200200A1
公开(公告)日：2015-12-30
申请号：PCT/US2015/036944
申请日：2015-06-22
申请人： THE UNIVERSITY OF TOLEDO
发明人： YAMAMOTO, Kana , VIAMAJALA, Sridhar , VARANASI, Sasidhar , NGUYEN, Kim , ABEL, Godwin , MUDIYANSELAGE, Ajith, Yapa
IPC分类号： C07C6/04
CPC分类号： C07C227/04 , C07C67/303 , C07C67/333 , C07C229/08 , C07C253/30 , C07C255/23 , C07C69/732 , C07C69/675
摘要： A concise method of producing nylon 11, 12, or 13 precursors from oleic acid or an ester of oleic acid is described. The method involves cross-metathesis reactions as the key C-C bond formation step. Subsequent steps are provided to convert the metathesis product to the corresponding nylon precursors. Also provided are the products of the method.
摘要翻译：描述了从油酸或油酸酯生产尼龙11,12或13前体的简明方法。该方法涉及交叉复分解反应作为关键的C-C键形成步骤。提供随后的步骤以将复分解产物转化成相应的尼龙前体。还提供了该方法的产品。

9. 发明申请

WO2016004299A1 RING CLOSING METATHESIS APPROACH TO PRODUCE PRECURSORS OF NYLON 11, 12, AND 13 FROM OLEIC ACID 审中-公开
标题翻译：生产尼龙前列腺素11,12和13的环状封闭细胞生物学方法
公开(公告)号：WO2016004299A1
公开(公告)日：2016-01-07
申请号：PCT/US2015/038976
申请日：2015-07-02
申请人： THE UNIVERSITY OF TOLEDO
发明人： YAMAMOTO, Kana , VIAMAJALA, Sridhar , VARANASI, Sasidhar , MUDIYANSELAGE, Ajith Yapa , ABEL, Godwin
IPC分类号： C07C6/04
CPC分类号： C07D225/02
摘要： Provided herein is a method of producing C11, C12, and C13 nylon precursors from oleic acid or esters of oleic acid, the method involving amide formation, ring-closing metathesis, and hydrogenation. Further provided are the products of the method described. Provided herein is a method for producing a lactam, the method comprising the steps of converting oleic acid or an ester of oleic acid into an amide having a general formula of H3C-(CH2)rCH=CH-(CH2)rCONR-(CH2)n-CH=CH2, wherein n is 1, 2, or 3, and R is either hydrogen or benzyl; subjecting the amide to a ring-closing metathesis reaction to produce an intermediate having a general formula of -(CH2)rCONR-(CH2) n-CH=CH2-, wherein n is 1, 2, or 3, R is either hydrogen or benzyl, and both ends are connected to each other; and hydrogenating the intermediate to produce a saturated lactam. In certain embodiments, the saturated lactam has a formula of -NH-(CH2) 10-CO-.
摘要翻译：本文提供了一种从油酸或油酸酯生产C11，C12和C13尼龙前体的方法，涉及酰胺形成，闭环复分解和氢化的方法。还提供了所述方法的产物。本发明提供了制备内酰胺的方法，该方法包括以下步骤：将油酸或油酸酯转化为通式为H3C-（CH2）rCH = CH-（CH2）rCONR-（CH2） n-CH = CH 2，其中n为1,2或3，并且R为氢或苄基; 使酰胺进行闭环复分解反应以产生具有通式为 - （CH 2）r CONR-（CH 2）n -CH = CH 2 - 的中间体，其中n为1,2或3，R为氢或苄基，并且两端彼此连接; 并氢化中间体以产生饱和内酰胺。在某些实施方案中，饱和内酰胺具有式-NH-（CH 2）10 -CO-的式。

10. 发明申请

WO2015066598A1 METHODS FOR HIGH YIELD PRODUCTION OF FURANS FROM BIOMASS SUGARS AT MILD OPERATING CONDITIONS 审中-公开
标题翻译：从生物量糖在奶牛营养条件下高产生产的方法
公开(公告)号：WO2015066598A1
公开(公告)日：2015-05-07
申请号：PCT/US2014/063661
申请日：2014-11-03
申请人： THE UNIVERSITY OF TOLEDO
发明人： ALIPOUR, Siamak , LI, Bin , VARANASI, Sasidhar , RELUE, Patricia , VIAMAJALA, Sridhar
IPC分类号： B01J19/00
CPC分类号： C12P17/04 , C07D307/50
摘要： Facile methods for high-yield furfural and HMF production from biomass sugars are described. The methods generally involve converting the biomass sugars in high yield to their ketose isomers, resulting in furan production under low temperature and pressure conditions with efficient recycling of the process streams.
摘要翻译：描述了生物质糖高产糠醛和HMF生产的简便方法。所述方法通常涉及将生物质糖高收率地转化为它们的酮糖异构体，从而在低温和高压条件下生产呋喃并有效回收工艺流。

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