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1. 发明申请

WO2016089432A2 POTENTIAL OF ZERO CHARGE-BASED CAPACITIVE DEIONIZATION 审中-公开
标题翻译：零电荷电容性离子化的潜力
公开(公告)号：WO2016089432A2
公开(公告)日：2016-06-09
申请号：PCT/US2015/000142
申请日：2016-01-15
申请人： UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION , GAO, Xin , OMOSEBI, Ayokunle , LANDON, James, Richardson , LIU, Kunlei
发明人： GAO, Xin , OMOSEBI, Ayokunle , LANDON, James, Richardson , LIU, Kunlei
IPC分类号： C02F1/469
CPC分类号： C02F1/4691 , C02F2001/46138 , C02F2209/05
摘要： The invention is a capacitive, aka electrostatic, deionization apparatus and method that solves the problem of short lifetime of conventional capacitive deiohization (CDI) and of membrane capacitive deionization (MCDI) devices and methods by shifting the Potential of Zero Charge of electrode surfaces through surface modifications. Such electrode surface modifications provide very long lifetime capacitive deionization devices and methods.
摘要翻译：本发明是一种电容式静电去离子装置和方法，它解决了常规电容去磁（CDI）和膜电容去离子（MCDI）装置和方法的短寿命问题，通过表面修饰使电极表面零电荷。这种电极表面改性提供了非常长寿命的电容去离子装置和方法。

2. 发明申请

WO2022173705A1 RECOVERY OF VALUABLE MATERIALS AND GRAPHITE FROM END-OF-LIFE LITHIUM-ION BATTERIES 审中-公开
公开(公告)号：WO2022173705A1
公开(公告)日：2022-08-18
申请号：PCT/US2022/015522
申请日：2022-02-07
申请人： UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION
发明人： GAO, Xin , LIU, Kunlei , HUANG, Neng
IPC分类号： B09B3/00 , C22B26/12 , H01M10/54
摘要： A method of recovering valuable materials from a black mass of lithium ion batteries may be broadly described as including the steps of decomposing the black mass to produce a reduced black mass, extracting lithium from the reduced black mass and separating and recovering magnetic alloy materials and non-magnetic materials from the reduced black mass. An apparatus for recovering valuable materials from a black mass of lithium ion batteries includes a thermal reactor, a stirring reactor, a solid-liquid separator, an oven and a magnet-assisted vibration device.

3. 发明公开

EP3044820A1 POTENTIAL OF ZERO CHARGE MODIFIED CARBON BASED ELECTRODE FOR DESALINATION 审中-公开
标题翻译： DURCH EIN NULLLADUNGSPOTENTIAL MODIFIZIERTE KOHLENSTOFFBASIERTE ELEKTRODE ZUR ENTSALZUNG
公开(公告)号：EP3044820A1
公开(公告)日：2016-07-20
申请号：EP14843583.7
申请日：2014-09-10
申请人： UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION
发明人： LANDON, James , LIU, Kunlei , GAO, Xin , OMOSEBI, Ayokunle
IPC分类号： H01M4/13
CPC分类号： H01M4/366 , C02F1/46109 , C02F2001/46138 , C02F2001/46142 , C02F2103/08 , H01M4/133
摘要： An electrode is provided which includes a carbon-based material coated with a film which modifies the material's potential of zero charge. A method for producing the electrode includes steps of infiltrating a woven carbon cloth with a solution containing resorcinol and formaldehyde, polymerizing the solution infiltrated woven carbon cloth, subjecting the infiltrated and polymerized woven carbon cloth to a solvent-exchange process, carbonizing the woven carbon cloth and coating the carbonized woven carbon cloth with a film.
摘要翻译：提供了一种电极，其包括涂覆有膜的碳基材料，其修饰材料的零电荷的电位。一种电极的制造方法，其特征在于，使用含有间苯二酚和甲醛的溶液浸渍编织碳布，聚合渗液的碳布，使渗透聚合的编织碳布进行溶剂交换处理，将编织碳布碳化并用薄膜涂覆碳化编织碳布。

4. 发明公开

EP3226992A2 POTENTIAL OF ZERO CHARGE-BASED CAPACITIVE DEIONIZATION 无效
标题翻译：零电荷电容性离子化的潜力
公开(公告)号：EP3226992A2
公开(公告)日：2017-10-11
申请号：EP15864882.4
申请日：2016-01-15
申请人： University of Kentucky Research Foundation
发明人： GAO, Xin , OMOSEBI, Ayokunle , LANDON, James, Richardson , LIU, Kunlei
IPC分类号： B01D15/36 , C25B9/04 , H01G2/22 , H01G4/04 , H01G5/012 , H01M10/05
CPC分类号： C02F1/4691 , C02F2001/46138 , C02F2209/05
摘要： The invention is a capacitive, aka electrostatic, deionization apparatus and method that solves the problem of short lifetime of conventional capacitive deionization (CDI) and of membrane capacitive deionization (MCDI) devices and methods by shifting the Potential of Zero Charge of electrode surfaces through surface modifications. Such electrode surface modifications provide very long lifetime capacitive deionization devices and methods.
摘要翻译：本发明是一种电容式静电去离子装置和方法，其通过将电极表面的零电荷电位移动通过表面来解决常规电容去极化（CDI）和膜电容去离子化（MCDI）装置和方法的短寿命问题修改。这种电极表面改性提供了非常长寿命的电容去离子装置和方法。

5. 发明公开

EP3868788A1 MULTI-SPECIFIC ANTIBODY, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 审中-实审
公开(公告)号：EP3868788A1
公开(公告)日：2021-08-25
申请号：EP20878020.5
申请日：2020-07-08
申请人： Gao, Xin
发明人： QIAN, Niliang , LI, Hongjie , YANG, Cuima , WANG, Fuyu , PAN, Xiujie , LIU, Yunhui , HU, Dongmei , GAO, Xin
IPC分类号： C07K16/46 , C12N15/13 , C12N15/63 , C12N5/10 , A61K39/395 , A61P35/00
摘要： The present application provides a multispecific antibody and preparation method and use thereof. The multispecific antibody comprises:
a) a Fab fragment specifically binding to a first antigen, wherein the Fab fragment consists of a light chain and CH1 and a variable region of a heavy chain;
b) a first peptide linker with the N-terminal end fused to the heavy chain;
c) a second peptide linker with the N-terminal end fused to the light chain,
wherein only one disulfide bond can be formed between the first and the second peptide linkers, and each of the first and the second peptide linkers is independently selected from the group consisting of a peptide linker comprising any of the sequences as set forth in SEQ ID NO.1-2, wherein X represents any amino acid other than Cys, or is absent.
The antibody can be readily produced by recombinant expression and can simultaneously target two different antigens or different epitopes of the same antigen, or multiple epitopes of more different antigens.

6. 发明申请

WO2011041013A1 ELECTROCHEMICAL DESALINATION SYSTEM AND METHOD 审中-公开
标题翻译：电化学脱盐系统及方法
公开(公告)号：WO2011041013A1
公开(公告)日：2011-04-07
申请号：PCT/US2010/042505
申请日：2010-07-20
申请人： GENERAL ELECTRIC COMPANY , NIU, Ran , YANG, Hai , BARBER, John, H. , HU, Min , XIONG, Rihua , CAI, Wei , GAO, Xin , LIU, Yunfeng
发明人： NIU, Ran , YANG, Hai , BARBER, John, H. , HU, Min , XIONG, Rihua , CAI, Wei , GAO, Xin , LIU, Yunfeng
IPC分类号： C02F1/469
CPC分类号： C02F1/4691 , C02F2103/08 , C02F2201/46135 , C02F2201/4614 , C02F2209/005
摘要： An electrochemical desalination system (10) includes a first and a second electrochemical device (12, 14) and a controller (18). The first and second electrochemical devices (12, 14) each comprises a electrochemical desalination module comprising at least one pair of electrodes (32, 33, 34, 35) and a compartment between each pair of electrodes (32, 33, 34, 35) for receiving an electrolyte solution. Each of the first and second electrochemical desalination devices comprises a plurality of successive operation cycles. Each cycle comprises a charging mode of operation for charging each pair of electrodes (32, 33, 34, 35) and for adsorbing ions in the electrolyte solution on the electrodes, and a discharging mode of operation for discharging the pair of electrodes (32, 33, 34, 35) and for desorbing ions from the pair of electrodes (32, 33, 34, 35). One of the first and second electrochemical desalination devices is in a discharging mode and the at least one pair of electrodes release electrical current, while the other of the first and second electrochemical desalination devices is in a charging mode of operation and receives the electrical current released from said one of the first and second electrochemical desalination device.
摘要翻译：电化学脱盐系统（10）包括第一和第二电化学装置（12,14）和控制器（18）。第一和第二电化学装置（12,14）各自包括电化学脱盐模块，其包括至少一对电极（32,33,34,35）和每对电极（32,33,34,35）之间的隔室，用于接收电解质溶液。第一和第二电化学脱盐装置中的每一个包括多个连续的操作循环。每个循环包括用于对每对电极（32,33,34,35）充电并用于将电解质中的离子吸附在电极上的充电操作模式，以及用于将一对电极（32,33,34） 33,34,35），并且用于从一对电极（32,33,34,35）解吸离子。第一和第二电化学脱盐装置之一处于放电模式，并且至少一对电极释放电流，而第一和第二电化学脱盐装置中的另一个处于充电操作模式并且接收释放的电流从所述第一和第二电化学脱盐装置中的一个。

7. 发明申请

WO2012088643A1 VACUUM CHAMBER METHOD TO FORM POLYMER COATINGS ON POROUS SUPPORT 审中-公开
标题翻译：在多孔支撑上形成聚合物涂层的真空室方法
公开(公告)号：WO2012088643A1
公开(公告)日：2012-07-05
申请号：PCT/CN2010/002227
申请日：2010-12-31
申请人： GENERAL ELECTRIC COMPANY , BARBER, John , YANG, Hai , LU, Su , MACDONALD, Russell, James , DENG, Zhigang , GAO, Xin
发明人： BARBER, John , YANG, Hai , LU, Su , MACDONALD, Russell, James , DENG, Zhigang , GAO, Xin
IPC分类号： H01M4/88 , H01M4/96
CPC分类号： H01M4/0402 , B05D1/32 , B05D5/12 , C02F1/4693 , C02F2001/46128 , C23C18/06 , H01M4/8657 , H01M4/8892 , H01M4/96 , H01M2004/8694 , Y02E60/50
摘要： A bi-polar electrode having ion exchange polymers on opposite faces (13A, 13B) of a porous substrate is formed using a method that includes providing an electrode substrate (12) with activated carbon layers on opposite faces (13A, 13B) of the electrode substrate (12), wherein said faces have an outer perimeter band (14) void of the activated carbon layers. Gaskets (16A, 16B) are placed against the outer perimeter band (14) of the electrode substrate (12) void of activated carbon and the electrode substrate (12) is clamped between two rigid plates (18A, 18B) to form a first airtight chamber (20A) on one side (15A) of the electrode substrate (12) and a second airtight chamber (20B) on the opposite side (15B) of the electrode substrate (12). A first polymerizable monomer mixture having an anion exchange group is added into the first chamber (20A) and a second polymerizable monomer mixture having a cation exchange group is added into the second chamber (20B). The first and second polymerizable monomer mixtures are then polymerized in an oven.
摘要翻译：在多孔基材的相对面（13A，13B）上具有离子交换聚合物的双极电极使用包括在电极的相对面（13A，13B）上设置活性碳层的电极基板（12）衬底（12），其中所述表面具有无活性碳层的外周边带（14）。垫圈（16A，16B）抵靠电极基底（12）的外周带（14）放置在活性炭的空隙处，并且电极基片（12）夹在两个刚性板（18A，18B）之间以形成第一气密在电极基板（12）的一侧（15A）上的室（20A）和电极基板（12）的相对侧（15B）上的第二气密室（20B）。将具有阴离子交换基团的第一可聚合单体混合物加入到第一室（20A）中，并且将具有阳离子交换基团的第二可聚合单体混合物加入到第二室（20B）中。然后将第一和第二可聚合单体混合物在烘箱中聚合。

8. 发明申请

WO2012003877A1 MILLING DEVICE WITH ADJUSTABLE MILLING OPERATION 审中-公开
标题翻译：具有可调磨削操作的铣削装置
公开(公告)号：WO2012003877A1
公开(公告)日：2012-01-12
申请号：PCT/EP2010/059872
申请日：2010-07-09
申请人： FREWITT FABRIQUE DE MACHINES SA , GAO, Xin , VIRDIS, Antoine
发明人： GAO, Xin
IPC分类号： B02C4/42 , B02C4/26 , B02C18/26 , B02C18/06
CPC分类号： B02C25/00 , B02C4/26 , B02C4/42 , B02C18/062 , B02C18/144 , B02C18/24 , B02C18/26 , B02C2023/165
摘要： A milling device (1) for performing a milling operation comprising a milling unit (2) comprising a housing (3) defining a milling chamber (16) that can be filled with a material to be milled, a rotor assembly (4) rotatably mounted in the housing (3), and a screen assembly (13) for fractionating the material milled by the rotor assembly (4) in movement and extending below the rotor assembly (4); and a drive unit (20) adapted for controlling the movements of the rotor assembly (4) relative to the screen assembly (13) during the milling operation; wherein said drive unit (20) is configured to produce an oscillating movement of the rotor assembly (4), the oscillating movement having an oscillation angle that can be varied during the milling operation when controlling the movements of the rotor assembly (4) relative to the screen assembly (13). The milling device (1) has improved milling efficiency.
摘要翻译：一种用于执行铣削操作的铣削装置（1），其包括铣削单元（2），所述铣削单元（2）包括限定可被待铣削材料填充的铣削室（16）的壳体（3），转子组件（4）在所述壳体（3）中，以及筛网组件（13），用于分级由所述转子组件（4）铣削的材料移动并延伸到所述转子组件（4）的下方; 以及驱动单元（20），其适于在所述铣削操作期间控制所述转子组件（4）相对于所述筛网组件（13）的运动; 其中所述驱动单元（20）构造成产生所述转子组件（4）的摆动运动，所述摆动运动具有摆动角度，所述摆动角度在所述铣削操作期间可以在控制所述转子组件（4）相对于屏幕组件（13）。铣削装置（1）具有提高的铣削效率。

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