专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20160199667A1 METHOD AND SYSTEM FOR DYNAMICALLY-TRIMMED SPOT SCANNING FOR ION THERAPY 审中-公开
标题翻译：用于离子治疗的动态斑点扫描的方法和系统
公开(公告)号：US20160199667A1
公开(公告)日：2016-07-14
申请号：US14897077
申请日：2014-07-03
申请人： UNIVERSITY OF IOWA RESEARCH FOUNDATION
发明人： Ryan Flynn , Daniel HYER , Dongxu WANG , Patrick HILL , Yves CLAEREBOUDT
IPC分类号： A61N5/10
CPC分类号： A61N5/1043 , A61N5/103 , A61N2005/1076 , A61N2005/1087 , A61N2005/1095 , G21K1/04 , G21K1/10
摘要： A spot scanning (SS) ion therapy system configured for dynamic trimming of an ion particle pencil beam to reduce the amount of the radiation dosage outside of a target boundary.
摘要翻译：一种点扫（SS）离子治疗系统，配置用于动态修整离子粒子笔束以减少靶边界外的辐射剂量。

2. 发明申请

US20140249406A1 COMPENSATOR-BASED BRACHYTHERAPY 审中-公开
标题翻译：基于补偿器的BRACHYTHERAPY
公开(公告)号：US20140249406A1
公开(公告)日：2014-09-04
申请号：US14072270
申请日：2013-11-05
申请人： UNIVERSITY OF IOWA RESEARCH FOUNDATION
发明人： Ryan Flynn , Yusung Kim , Xing Li , Kee-Ho Yuen
IPC分类号： A61N5/10
CPC分类号： A61N5/1001 , A61N5/1014 , A61N2005/1012 , A61N2005/1096
摘要： Compensator-based brachytherapy (CBT) for treatment of cancerous tumors or other pathologic tissues. CBT permits, in one aspect, increased dosage conformity for non-radially symmetric tumors by utilizing a device that can shield radiation emanated from an electronic brachytherapy (BT) source or non-electronic BT source. The device can comprise, in one aspect, a radiation compensator having a treated surface that comprises a position-dependent thickness based at least on a radiation therapy plan specific to a patient and geometry of a patient region to be treated. In an additional or alternative aspect, the device can comprise a source of radiation movably inserted into an enclosure coupled to the radiation compensator. As part of CBT, in one implementation, the radiation source can reside at a plurality of locations within the radiator compensator during a respective plurality of dwell times based on the radiation therapy plan.
摘要翻译：用于治疗癌性肿瘤或其他病理组织的基于补偿剂的近距离放射治疗（CBT）。 CBT允许在一个方面通过利用可以屏蔽从电子近距离放射治疗（BT）源或非电子BT源发出的辐射的装置来增加非径向对称肿瘤的剂量一致性。在一个方面，该装置可以包括具有经处理的表面的辐射补偿器，该处理的表面至少基于患者特有的放射治疗计划和待治疗的患者区域的几何形状包括位置依赖性厚度。在附加或替代方面，该装置可以包括可移动地插入耦合到辐射补偿器的外壳中的辐射源。作为CBT的一部分，在一个实施方案中，辐射源可以在基于辐射治疗计划的相应的多个停留时间期间驻留在辐射器补偿器内的多个位置处。

3. 发明申请

US20190126064A1 A ROTATING SHIELD BRACHYTHERAPY SYSTEM 审中-公开
公开(公告)号：US20190126064A1
公开(公告)日：2019-05-02
申请号：US16092851
申请日：2017-04-19
申请人： University of Iowa Research Foundation
发明人： Ryan Flynn , Hossein Dadkhah , Kaustubh Patwardhan , Myung Cho
IPC分类号： A61N5/10
摘要： An apparatus and method for using rotating shield brachytherapy (RSBT). In an aspect, the RSBT system and method can be used to maintain or increase tumor dose relative to conventional techniques with a dramatic reduction in radiation dose to the urethra, rectum, and bladder in the treatment of prostate cancer through placing partially shielded radiation sources away from sensitive tissues. In an aspect, the invention is an apparatus and method for the precise angular and linear positioning of multiple partially-shielded radiation sources in interstitial needles. In a further aspect, the invention comprises a monitoring and control apparatus for the precise and simultaneous angular positioning of multiple shield-containing catheters in the RBST system by measuring and correcting deviations between actual and desired catheter angular positions and depth in real time before and during treatment delivery.

4. 发明授权

US09776017B2 Method and system for dynamically-trimmed spot scanning for ion therapy 有权
公开(公告)号：US09776017B2
公开(公告)日：2017-10-03
申请号：US14897077
申请日：2014-07-03
申请人： UNIVERSITY OF IOWA RESEARCH FOUNDATION
发明人： Ryan Flynn , Daniel Hyer , Dongxu Wang , Patrick Hill , Yves Claereboudt
IPC分类号： A61N5/10 , G21K1/04 , G21K1/10
CPC分类号： A61N5/1043 , A61N5/103 , A61N2005/1076 , A61N2005/1087 , A61N2005/1095 , G21K1/04 , G21K1/10
摘要： A spot scanning (SS) ion therapy system configured for dynamic trimming of an ion particle pencil beam to reduce the amount of the radiation dosage outside of a target boundary.

5. 发明申请

US20170165500A1 ADVANCED ROTATING-SHIELD BRACHYTHERAPY AND PLANNING OF THE SAME 审中-公开
公开(公告)号：US20170165500A1
公开(公告)日：2017-06-15
申请号：US14803427
申请日：2015-07-20
申请人： UNIVERSITY OF IOWA RESEARCH FOUNDATION
发明人： Ryan Flynn , Xiaodong WU , Yunlong Liu , Quentin Adams , Drake Edwards , Shirin Enger , Brittany Rae Woodin , Hossein Dadkhan
IPC分类号： A61N5/10
CPC分类号： A61N5/1002 , A61N5/1007 , A61N5/1027 , A61N5/103 , A61N5/1044 , A61N2005/1005 , A61N2005/1094
摘要： Systems and methods for rotating shield brachytherapy. In an aspect, some of the systems and methods can be used to facilitate shield selection for use in rotating shield brachytherapy. In an aspect, the invention is a shielded needle or catheter system with a rotational controller for delivering radioisotope-based interstitial rotating shield brachytherapy (I-RSBT). In an aspect, the catheter system can utilize paddle-based RSBT. Further provided are methods and systems for helical RSBT.

6. 发明授权

US11013935B2 Rotating shield brachytherapy system 有权
公开(公告)号：US11013935B2
公开(公告)日：2021-05-25
申请号：US16092851
申请日：2017-04-19
申请人： University of Iowa Research Foundation
发明人： Ryan Flynn , Hossein Dadkhah , Kaustubh Patwardhan , Myung Cho
IPC分类号： A61N5/10 , A61B18/00
摘要： An apparatus and method for using rotating shield brachytherapy (RSBT). In an aspect, the RSBT system and method can be used to maintain or increase tumor dose relative to conventional techniques with a dramatic reduction in radiation dose to the urethra, rectum, and bladder in the treatment of prostate cancer through placing partially shielded radiation sources away from sensitive tissues. In an aspect, the invention is an apparatus and method for the precise angular and linear positioning of multiple partially-shielded radiation sources in interstitial needles. In a further aspect, the invention comprises a monitoring and control apparatus for the precise and simultaneous angular positioning of multiple shield-containing catheters in the RBST system by measuring and correcting deviations between actual and desired catheter angular positions and depth in real time before and during treatment delivery.

7. 发明授权

US10029118B2 Advanced rotating-shield brachytherapy and planning of the same 有权
公开(公告)号：US10029118B2
公开(公告)日：2018-07-24
申请号：US14803427
申请日：2015-07-20
申请人： UNIVERSITY OF IOWA RESEARCH FOUNDATION
发明人： Ryan Flynn , Hossein Dadkhah
IPC分类号： A61N5/10
摘要： Systems and methods for rotating shield brachytherapy. In an aspect, some of the systems and methods can be used to facilitate shield selection for use in rotating shield brachytherapy. In an aspect, the invention is a shielded needle or catheter system with a rotational controller for delivering radioisotope-based interstitial rotating shield brachytherapy (I-RSBT). In an aspect, the catheter system can utilize paddle-based RSBT. Further provided are methods and systems for helical RSBT.

8. 发明申请

US20180200540A1 SYSTEM AND METHOD FOR AN INTENSITY MODULATED RADIATION THERAPY DEVICE 审中-公开
公开(公告)号：US20180200540A1
公开(公告)日：2018-07-19
申请号：US15408824
申请日：2017-01-18
申请人： UNIVERSITY OF IOWA RESEARCH FOUNDATION
发明人： Ryan Flynn , Junyi Xia , Timothy J. Waldron , Yusung Kim , Bryan G. Allen , Brennen M. Wears , Hongtao Ding
IPC分类号： A61N5/10
CPC分类号： A61N5/1001 , A61N5/1045 , A61N5/1083
摘要： Systems and methods for low energy radiation x-ray radiation therapy system for use at a target within a cavity of a subject. In an aspect, the system uses an aperture shaping device used to shape the radiation beam from the low energy radiation source. In an aspect, the aperture shaping device includes a plurality of leaf assemblies which include leaves configured to form the aperture and engage the radiation beam. In an aspect, the present invention utilizes a geared mechanics approach to create an aperture using only one dial input. The design ensures that the field size of the collimator remains a constant shape as it is opened and closed. In an aspect, the overall size of the collimator may be scaled to accommodate various radiation therapy requirements.

9. 发明申请

US20150367144A1 ADVANCED ROTATING-SHIELD BRACHYTHERAPY AND PLANNING OF THE SAME 审中-公开
标题翻译：先进的旋转屏蔽及其规划
公开(公告)号：US20150367144A1
公开(公告)日：2015-12-24
申请号：US14418274
申请日：2013-03-15
申请人： University of Iowa Research Foundation
发明人： Ryan Flynn , Xiaodong Wu , Yunlong Liu , Quentin Adams , Drake Edwards , Shirin Enger , Brittany Rae Woodin
IPC分类号： A61N5/10
CPC分类号： A61N5/1031 , A61N5/1001 , A61N5/1007 , A61N5/1027 , A61N5/103 , A61N5/1039 , A61N5/1048 , A61N2005/1008 , A61N2005/1018 , A61N2005/1035 , A61N2005/1074 , A61N2005/1094
摘要： Systems and methods for rotating shield brachytherapy. In an aspect, some of the systems and methods can be used to facilitate shield selection for use in rotating shield brachytherapy. In an aspect, the invention is a shielded needle or catheter system with a rotational controller for delivering radioisotope-based interstitial rotating shield brachytherapy (I-RSBT), In an aspect, I-RSBT needles can deliver dose distributions that can be non-radially symmetric about each needle, enabling reduced doses to sensitive normal tissues. Further provided are methods and systems for selecting an emission angle for use in S-RSBT and for sequencing the rotating shields. Further provided are methods and system for the multiple application of M-RSBT in a single setting.
摘要翻译：旋转屏蔽近距离放射治疗的系统和方法。在一个方面，可以使用一些系统和方法来促进用于旋转屏蔽近距离放射治疗的屏蔽选择。一方面，本发明是具有用于输送基于放射性同位素的间隙旋转屏蔽近距离放射治疗（I-RSBT）的旋转控制器的屏蔽针或导管系统。一方面，I-RSBT针可以递送可以非径向的剂量分布对称关于每个针，使敏感正常组织减少剂量。还提供了用于选择在S-RSBT中使用的发射角并用于对旋转屏蔽进行排序的方法和系统。还提供了在单个设置中多次应用M-RSBT的方法和系统。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式