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    • 1. 发明申请
    • ENZYME-ASSISTED NANOLITHOGRAPHY
    • 酶辅助纳米尺度
    • WO2005080255A1
    • 2005-09-01
    • PCT/EP2005/001788
    • 2005-02-21
    • UNIVERSITÄT BREMENRADMACHER, ManfredRIEMENSCHNEIDER, Leif
    • RADMACHER, ManfredRIEMENSCHNEIDER, Leif
    • B82B3/00
    • B82B3/00G01Q70/18
    • A method for enzyme-assisted nanolithography and devices for performing such methods are provided. Furthermore, supports with surfaces obtainable by the method according to the present invention are described as well as devices containing such supports, e.g. chips, microarrays and biosensors. In addition, methods for the specific coating of a tip with enzyme or effector molecules are provided, which can particularly serve for the application in scanning probe microscopy. The described methods, surfaces, supports, devices, tips and scanning probe microscopes can be used for the storage and/or analysis of data, in cell biology or for conducting measurement and examination methods, like e.g. in forensics, environmental and chemical analytics, molecular biology or pharmaceutical diagnostics.
    • 提供了酶辅助纳米光刻的方法和用于执行这些方法的装置。 此外,描述了通过根据本发明的方法可获得的表面的载体以及含有这种载体的装置,例如, 芯片,微阵列和生物传感器。 此外,提供了用酶或效应分子特异性涂覆尖端的方法,其可特别用于扫描探针显微镜中的应用。 所描述的方法,表面,支撑,装置,尖端和扫描探针显微镜可用于数据的存储和/或分析,细胞生物学或用于进行测量和检查方法,例如。 在法医,环境和化学分析,分子生物学或制药诊断。