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1. 发明申请

WO2015009260A3 A WOUND HEALING HERBAL PRODUCT 审中-公开
标题翻译：创新治疗草药产品
公开(公告)号：WO2015009260A3
公开(公告)日：2015-04-23
申请号：PCT/TR2014000273
申请日：2014-07-16
申请人： UNIV YEDITEPE
发明人： SAHIN FIKRETTIN , DEMIRCI SELAMI , DOGAN AYSEGUL , DEMIRCI SERPIL
IPC分类号： A61K36/80
CPC分类号： A61K36/80 , A61K9/0014 , A61K2236/00
摘要： In the embodiment of the invention, a product which enables wound healing and accelerates cell division and veining is obtained by using the plant extract obtained from Verbascum speciosum leaves via extraction. The obtained product can be applied to the cells of L929 (Rat Fibroplast Cell Line), HF (Human Dermal Fibroplast Cell Line) and HUVEC (Human Umbilical Vein Endothelial Cells) which is human endothelial cell line.
摘要翻译：在本发明的实施方案中，通过使用通过提取从Verbascum speciosum叶中获得的植物提取物获得能够伤口愈合并加速细胞分裂和脉络染色的产品。所得产物可应用于作为人内皮细胞系的L929（大鼠纤维板细胞系），HF（人真皮成纤维细胞系）和HUVEC（人脐静脉内皮细胞）的细胞。

2. 发明申请

WO2014196940A3 BORON ADDED ANTIMICROBIAL JOINT SEALANT 审中-公开
标题翻译： BORON添加抗微生物联合密封剂
公开(公告)号：WO2014196940A3
公开(公告)日：2015-02-26
申请号：PCT/TR2014000145
申请日：2014-06-03
申请人： UNIV YEDITEPE
发明人： SAHIN FIKRETTIN , DEMIRCI SELAMI , USTAOGLU ZEYNEP
IPC分类号： A01N55/08 , A01N25/08 , A01N25/34 , A01P1/00 , A01P3/00
CPC分类号： A01N59/14 , A01N25/10
摘要： The present invention relates to obtaining an antimicrobial joint sealant obtained by adding boron compounds therein. The surfaces of all kinds of raw materials and semi finished products produced from the joint sealant material of the present invention are protected against microbial contamination and degradation, corrosion and decay. In the invention wherein sodium borate ((Na2O)(B2O3)5.10H2O), zinc borate (2ZnO.3B2O3.3.5H2O) and potassium borate (K2B4O7.4H2O) are used as boron derivatives; it is determined that Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Botrytis spp., Aspergillus spp., Penicillium spp., Fusarium spp., Alternaria spp., Penicillium spp., and Candida spp. can be controlled by means of the said materials added to the joint sealant.
摘要翻译：本发明涉及通过在其中加入硼化合物获得的抗微生物接头密封剂。由本发明的接合密封剂材料生产的各种原材料和半成品的表面可以防止微生物污染和降解，腐蚀和腐蚀。在硼酸钠（（Na2O）（B2O3）5.10H2O），硼酸锌（2ZnO.3B2O3.3.5H2O）和硼酸钾（K2B4O7.4H2O）作为硼衍生物的本发明中，确定大肠杆菌，金黄色葡萄球菌，铜绿假单胞菌，葡萄孢属，曲霉属，青霉属，镰刀菌属，链格孢属，青霉属和假丝酵母属。可以通过添加到接头密封剂中的所述材料来控制。

3. 发明申请

WO2015009261A2 PRODUCT USED IN DIFFERENTIATION OF HUMAN TOOTH STEM CELLS 审中-公开
标题翻译：产品用于人类干细胞的分化
公开(公告)号：WO2015009261A2
公开(公告)日：2015-01-22
申请号：PCT/TR2014000274
申请日：2014-07-16
申请人： UNIV YEDITEPE
发明人： SAHIN FIKRETTIN , DEMIRCI SELAMI , DOGAN AYSEGUL , TASLI PAKIZE NESLIHAN
CPC分类号： C12N5/0654 , C12N2500/05 , C12N2500/38 , C12N2500/42 , C12N2501/39 , C12N2506/1361
摘要： The present invention discloses a boron containing product used in differentiation of human tooth germ stem cells. Sodium pentaborate pentahydrate and other boron compounds are used in the stem cell differentiation of the present invention. The invention is a product which can be applied in soft and hard tissue and organ regeneration, repair, healing and cell production technologies.
摘要翻译：本发明公开了用于人类牙胚干细胞分化的含硼产品。五硼酸五钠和其他硼化合物用于本发明的干细胞分化中。本发明是一种可应用于软硬组织和器官再生，修复，愈合和细胞生产技术的产品。

4. 发明申请

WO2012011085A3 KIT USEFUL FOR DETECTING DONKEY MEAT PRESENT IN MEAT 审中-公开
标题翻译：用于检测肉中的东西肉汤的试剂盒有用
公开(公告)号：WO2012011085A3
公开(公告)日：2012-07-26
申请号：PCT/IB2011053292
申请日：2011-07-23
申请人： UNIV YEDITEPE , YETIM HASAN , SAHIN FIKRETTIN , KESMEN ZULAL
发明人： YETIM HASAN , SAHIN FIKRETTIN , KESMEN ZULAL
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6881 , C12Q1/6851 , C12Q1/6888 , C12Q2600/158
摘要： The present invention relates to a kit comprising specific primer-probe set which is used for detecting donkey meat present in meat products by means of real-time PCR TaqMan probe technique. In the present invention contamination of donkey meat up to 0.1 picogram is enabled to be detected. The specific detection of donkey meat is made possible in raw and heat treated meat mixtures, by means of no cross-reaction until 40th cycle with horse, pork, bovine, ovine, chicken and turkey species with the kit specific to the donkey species.
摘要翻译：本发明涉及一种用于通过实时PCR TaqMan探针技术检测肉制品中存在的驴肉的特异性引物 - 探针组的试剂盒。在本发明中，可以检测到驴肉的污染物高达0.1皮克。驴肉的特异性检测可以在生肉和热处理的肉混合物中进行，通过与驴物种特异性的试剂盒不用交叉反应，直到第40个循环，马，猪肉，牛，羊，鸡和火鸡物种。

5. 发明申请

WO2015053726A3 ANTI-OBESITY PRODUCT 审中-公开
标题翻译：抗生素产品
公开(公告)号：WO2015053726A3
公开(公告)日：2015-07-16
申请号：PCT/TR2014000365
申请日：2014-10-01
申请人： UNIV YEDITEPE
发明人： SAHIN FIKRETTIN , DEMIRCI SELAMI , DOGAN AYSEGUL
IPC分类号： A61K31/69 , A61K33/22 , A61P1/04 , A61P3/00 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/10 , A61P9/12 , A61P13/12 , A61P19/02
CPC分类号： A61K33/22 , A61K31/69 , A61K2300/00
摘要： The present invention relates to a boron-containing product that may be used in obesity treatment. The invention provides an inexpensive and reliable anti-obesity product which is not toxic to the other tissues and organs of the body. The product of the invention comprises boric acid (BA) and sodium pentaborate pentahydrate (NaB).
摘要翻译：本发明涉及可用于肥胖症治疗的含硼产品。本发明提供了廉价且可靠的抗肥胖产品，其对身体的其他组织和器官是无毒的。本发明的产品包括硼酸（BA）和五硼酸钠五水合物（NaB）。

6. 发明申请

WO2015009260A9 A WOUND HEALING HERBAL PRODUCT 审中-公开
标题翻译：创伤愈合草药产品
公开(公告)号：WO2015009260A9
公开(公告)日：2015-06-25
申请号：PCT/TR2014000273
申请日：2014-07-16
申请人： UNIV YEDITEPE
发明人： SAHIN FIKRETTIN , DEMIRCI SELAMI , DOGAN AYSEGUL , DEMIRCI SERPIL
IPC分类号： A61K36/80
CPC分类号： A61K36/80 , A61K9/0014 , A61K2236/00
摘要： In the embodiment of the invention, a product which enables wound healing and accelerates cell division and veining is obtained by using the plant extract obtained from Verbascum speciosum leaves via extraction. The obtained product can be applied to the cells of L929 (Rat Fibroplast Cell Line), HF (Human Dermal Fibroplast Cell Line) and HUVEC (Human Umbilical Vein Endothelial Cells) which is human endothelial cell line.
摘要翻译：在本发明的实施方案中，通过提取使用从特比斯特叶获得的植物提取物来获得使伤口愈合并加速细胞分裂和脉络化的产品。所得产物可以用于人内皮细胞系L929（大鼠成纤维细胞系），HF（人真皮成纤维细胞系）和HUVEC（人脐静脉内皮细胞）的细胞。

7. 发明申请

WO2014053906A8 THE APPLICATION OF STEM CELLS IN THE ORTHODONTIC MAXILLARY EXPANSION 审中-公开
标题翻译：干细胞在正常超最大扩张中的应用
公开(公告)号：WO2014053906A8
公开(公告)日：2015-05-14
申请号：PCT/IB2013002203
申请日：2013-10-04
申请人： UNIV YEDITEPE
发明人： SAHIN FIKRETTIN , YALVAC MEHMET EMIR , EKIZER ABDULLAH , UYSAL TANCAN , SONMEZ MEHMET FATIH
IPC分类号： A61K35/28 , A61P19/08
CPC分类号： A61K35/28 , A61C7/10
摘要： This invention relates to the contributions of the bone marrow- and adipose tissue- derived mesenchymal stem cells applied following the maxillary expansion - a frequently used method for the orthodontic treatment - to the healing of the expanded bone tissues. In the invention, adipose tissue and bone marrow-derived stem cell applications increased the healing and quality of the bones following the maxillary expansion and the applied stem cells were involved in the bone structure. Thus, the relapse following the maxillary expansion treatment was avoided. This application will shorten the treatment period for patients undergoing the maxillary expansion treatment and the patients will not have to use apparatus for a long period of time.
摘要翻译：本发明涉及在上颌扩张之后应用的骨髓和脂肪组织衍生的间充质干细胞（经常使用的正畸治疗方法）对扩张的骨组织愈合的贡献。在本发明中，脂肪组织和骨髓来源的干细胞应用增加了上颌扩张后骨骼的愈合和质量，并且所应用的干细胞参与骨结构。因此，避免了上颌扩张治疗后的复发。该应用将缩短上颌扩张治疗患者的治疗期，患者长时间不用使用器械。

8. 发明申请

WO2014053906A3 THE APPLICATION OF STEM CELLS IN THE ORTHODONTIC MAXILLARY EXPANSION 审中-公开
标题翻译：干细胞在正畸扩张中的应用
公开(公告)号：WO2014053906A3
公开(公告)日：2014-05-30
申请号：PCT/IB2013002203
申请日：2013-10-04
申请人： UNIV YEDITEPE
发明人： SAHIN FIKRETTIN , YALVAC MEHMET EMIR , EKIZER ABDULLAH , UYSAL TANCAN
IPC分类号： A61K35/28 , A61P19/08
CPC分类号： A61K35/28 , A61C7/10
摘要： This invention relates to the contributions of the bone marrow- and adipose tissue- derived mesenchymal stem cells applied following the maxillary expansion - a frequently used method for the orthodontic treatment - to the healing of the expanded bone tissues. In the invention, adipose tissue and bone marrow-derived stem cell applications increased the healing and quality of the bones following the maxillary expansion and the applied stem cells were involved in the bone structure. Thus, the relapse following the maxillary expansion treatment was avoided. This application will shorten the treatment period for patients undergoing the maxillary expansion treatment and the patients will not have to use apparatus for a long period of time.
摘要翻译：本发明涉及在扩张的骨组织愈合后上颌骨扩张 - 一种常用的正畸治疗方法 - 之后应用的骨髓和脂肪组织衍生的间充质干细胞的贡献。在本发明中，脂肪组织和骨髓衍生的干细胞应用增加了上颌骨扩张后骨的愈合和质量，并且所应用的干细胞参与了骨结构。因此，避免了上颌扩张治疗后的复发。此应用将缩短上颌扩张治疗患者的治疗周期，患者不必长时间使用仪器。

9. 发明专利

CA3115456A1 USE OF MUTANT P53 GENE TARGETED LEAD BORATE NANOPARTICLES IN CANCER TREATMENT AND PRODUCTION METHOD OF THESE NANOPARTICLES 未知
公开(公告)号：CA3115456A1
公开(公告)日：2020-04-30
申请号：CA3115456
申请日：2018-11-08
申请人： UNIV YEDITEPE
发明人： SAHIN FIKRETTIN , TASLI PAKIZE NESLIHAN , KIRBAS OGUZ KAAN , HAYAL TAHA BARTU , BOZKURT BATUHAN TURHAN , BULBUL BERNA , BEYAZ SEDA
IPC分类号： A61K33/241 , A61P35/00
摘要： The present invention relates to use of nano-sized lead borate compounds for treatment purposes due to their selective anticancer activity on p53 mutant breast cancer cell line, T47D. The method of synthesizing nano-sized lead borates of the present invention comprises the steps of preparing a borate buffer solution by sodium hydroxide and boric acid, dissolving lead nitrate (and preferably PEG) in distilled water by stirring, mixing the borate buffer solution with the lead nitrate (and preferably PEG) solution, washing the resulting solution with distilled water and drying to remove the impurities.

10. 发明专利

DK2983641T3 POLYMERBASERET HYDROGEL 未知
公开(公告)号：DK2983641T3
公开(公告)日：2020-03-16
申请号：DK14737346
申请日：2014-04-08
申请人： UNIV YEDITEPE
发明人： SAHIN FIKRETTIN , DEMIRCI SELAMI , DOGAN AYSEGUL
IPC分类号： A61Q19/08 , A61K8/04 , A61K8/19 , A61K8/90 , A61K9/00 , A61K47/32 , A61K47/34 , A61L15/26 , A61L15/44 , A61L15/46 , A61L26/00 , A61Q17/00

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