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    • 2. 发明专利
    • Vascular characterization using ultrasound imaging
    • NZ615910A
    • 2015-11-27
    • NZ61591012
    • 2012-04-13
    • UNIV MINNESOTA
    • EBBINI EMAD SLIU DALONGWAN YAYUNCASPER ANDREW J
    • A61B8/08A61B8/06
    • An imaging method and a system for vascular imaging are disclosed. The system comprises one or more ultrasound transducers and a processing apparatus. The one or more transducers are configured to deliver ultrasound energy to a vascular region resulting in pulse-echo data therefrom. The processing apparatus is configured to control the capture of pulse-echo data at a frame rate such that measured displacement of a vessel wall defining at least one portion of a blood vessel in the vascular region and measured average blood flow through the at least one portion of the blood vessel have a quasi-periodic profile over time to allow motion tracking of both the vessel wall and the blood flow simultaneously; generate strain and shear strain image data for the region in which the at least one portion of the vessel is located using speckle tracking. The speckle tracking comprises using multi-dimensional correlation of pulse-echo data of one or more speckle regions undergoing deformation in the region in which the at least one portion of a blood vessel is located and the multi-dimensional correlation comprises determining a cross-correlation peak for the sampled pulse-echo data based on phase and magnitude gradients ofthe cross-correlated pulse-echo data; and The processing apparatus is further configured to identify at least one vascular characteristic of the vascular region in which at least one portion of a blood vessel is located based on the strain and shear strain image data. The at least one vascular characteristic comprises at least one of a flow characteristic associated with flow through the blood vessel, a structural characteristic associated with the blood vessel, and a hemodynamic characteristic associated with the blood vessel