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1. 发明申请

WO03029217A3 PYRIDINIC SULFONAMIDE DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF 审中-公开
标题翻译：吡啶磺酰胺衍生物，其生产方法及其用途
公开(公告)号：WO03029217A3
公开(公告)日：2003-08-28
申请号：PCT/EP0210532
申请日：2002-09-19
申请人： UNIV LIEGE , DELARGE JACQUES , PIROTTE BERNARD , DOGNE JEAN-MICHEL , DE LEVAL XAVIER , JULEMONT FABIEN
发明人： DELARGE JACQUES , PIROTTE BERNARD , DOGNE JEAN-MICHEL , DE LEVAL XAVIER , JULEMONT FABIEN
IPC分类号： C07D213/00 , A61K31/44 , A61P29/00 , A61P43/00 , C07D213/76 , C07D213/89
CPC分类号： C07D213/76 , C07D213/89
摘要： New pyridinic sulfonamide derivatives represented by a general formula (I), wherein R1, represents a mono- or polyhalogenated Cl-12-alkyl or a mono- or poly-halogenated C3-8-cycloalkyl group. The method of production of such derivatives and their use as active therapeutic substance in the treatment of diseases such as inflammation, arthrosis, cancer, angiogenesis and asthma are also reported.
摘要翻译：由通式（I）表示的新的吡啶磺酰胺衍生物，其中R 1表示单卤代或多卤代C 12-12 - 烷基或单 - 或多 - 卤代C 3-8 - 环烷基。还报道了这样的衍生物的制造方法及其作为活性治疗物质用于治疗诸如炎症，关节病，癌症，血管发生和哮喘的疾病的用途。

2. 发明专利

CA2460144C PYRIDINIC SULFONAMIDE DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF 未知
公开(公告)号：CA2460144C
公开(公告)日：2010-11-02
申请号：CA2460144
申请日：2002-09-19
申请人： UNIV LIEGE
发明人： DELARGE JACQUES , PIROTTE BERNARD , DOGNE JEAN-MICHEL , DE LEVAL XAVIER , JULEMONT FABIEN
IPC分类号： C07D213/00 , C07D213/76 , A61K31/44 , A61P29/00 , A61P43/00 , C07D213/89
摘要： New pyridinic sulfonamide derivatives represented by a general formula (I), wherein R~1, represents a mono- or polyhalogenated C~l-12-alkyl or a mono- or poly-halogenated C~3-8-cycloalkyl group. The method of production of such derivatives and their use as active therapeutic substance in the treatment of diseases such as inflammation, arthrosis, cancer, angiogenesis and asthma are also reported.

3. 发明专利

ES2324705T3 DERIVADOS SULFONAMIDA PIRIDINICOS, METODO DE PRODUCCION Y SU USO. 未知
公开(公告)号：ES2324705T3
公开(公告)日：2009-08-13
申请号：ES02772326
申请日：2002-09-19
申请人： UNIV LIEGE
发明人： DELARGE JACQUES , PIROTTE BERNARD , DOGNE JEAN-MICHEL , DE LEVAL XAVIER , JULEMONT FABIEN
IPC分类号： C07D213/00 , C07D213/76 , A61K31/44 , A61P29/00 , A61P43/00 , C07D213/89
摘要： Derivados sulfonamida piridínicos representados por una Fórmula general (I):** ver fórmula** en donde A representa un nitrógeno o un grupo -N=O; X representa Oxígeno, Azufre o un elemento seleccionado del grupo que consiste de (-NR3, -CR3R4, -SO, -SO2, o -CO); en donde R3 y R4 que pueden ser idénticos o diferentes, denotan cada uno independientemente un elemento seleccionado del grupo que consiste de (hidrógeno, un alquilo C 1-12 mono o polihalogenado, un cicloalquilo C 3-8 mono o polihalogenado, un alquilo C 1-12 o un cicloalquilo C 3-8); R1 representa un alquilo C1-12 mono o polihalogenado o un grupo cicloalquilo C3-8 mono o polihalogenado; R 2 representa un grupo cicloalquilo C 3-8 o un grupo arilo sustituido o no se sustituye por uno o varios elementos seleccionado del grupo que consiste de (halógeno, alquilo C1-12, cicloalquilo C3-8, R1, hidroxi, alcoxi C1-6, alcoxi C1-6-alquilo C1-6, nitro, amino, ciano, cianometilo; perhalometilo, monoalquilo C 1-6- o dialquilamino, sulfamaceiteo, alquiltio C 1-6, alquilsulfonilo C 1-6, alquilsulfinilo C 1-6, formilo, alquilcarbonilamino C 1-6,- R 5 ariltio, R 5 arilsulfinilo, R 5 arilsulfonilo, alcoxicarbonilo C 1-6, alcoxicarbonilo C1-6-, -alquilo C1-6; carbamilo; carbamilmetilo; monoalquilo C1-6- o dialquilaminocarbonilo, monoalquilo C1-6o dialquilaminotiocarbonilo, ureido, monoalquilo C1-6- o dialquilaminocarbonilamino, tioureido, monoalquilo C1-6o dialquilaminotiocarbonilamino, monoalquilo C1-6- o dialquilaminosulfonilo, carboxi, carboxi-alquilacilo C1-6, R5 arilo, R 5 arilalquilo, R 5 ariloxi), en donde R5 denota uno o varios grupos seleccionados de hidrógeno, alquilo C1-6, halógeno, hidroxi o alcoxi C1-6, y arilo denota fenilo, 1-naftilo o 2-naftilo.

4. 发明专利

AT426593T 未知
公开(公告)号：AT426593T
公开(公告)日：2009-04-15
申请号：AT02772326
申请日：2002-09-19
申请人： UNIV LIEGE
发明人： DELARGE JACQUES , PIROTTE BERNARD , DOGNE JEAN-MICHEL , DE LEVAL XAVIER , JULEMONT FABIEN
IPC分类号： C07D213/00 , C07D213/76 , A61K31/44 , A61P29/00 , A61P43/00 , C07D213/89

5. 发明专利

DE60231729D1 未知
公开(公告)号：DE60231729D1
公开(公告)日：2009-05-07
申请号：DE60231729
申请日：2002-09-19
申请人： UNIV LIEGE
发明人： DELARGE JACQUES , PIROTTE BERNARD , DOGNE JEAN-MICHEL , DE LEVAL XAVIER , JULEMONT FABIEN
IPC分类号： C07D213/00 , C07D213/76 , A61K31/44 , A61P29/00 , A61P43/00 , C07D213/89

6. 发明专利

AU2002337116B2 Pyridinic sulfonamide derivatives, method of production and use thereof 未知
公开(公告)号：AU2002337116B2
公开(公告)日：2008-01-31
申请号：AU2002337116
申请日：2002-09-19
申请人： UNIV LIEGE
发明人： LEVAL XAVIER DE , DELARGE JACQUES , JULEMONT FABIEN , DOGNE JEAN-MICHEL , PIROTTE BERNARD
IPC分类号： C07D213/00 , A61K31/44 , A61P29/00 , A61P43/00 , C07D213/76 , C07D213/89
摘要： New pyridinic sulfonamide derivatives represented by a general formula (I), wherein R 1 represents a mono- or polyhalogenated C 1-12 -alkyl or a mono- or polyhalogenated C 3-8 -cycloalkyl group. The method of production of such derivatives and their use as active therapeutic substance in the treatment of diseases such as inflammation, arthrosis, cancer, angiogenesis and asthma are also reported.

7. 发明专利

CA2460144A1 PYRIDINIC SULFONAMIDE DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF 未知
公开(公告)号：CA2460144A1
公开(公告)日：2003-04-10
申请号：CA2460144
申请日：2002-09-19
申请人： UNIV LIEGE
发明人： DELARGE JACQUES , PIROTTE BERNARD , DOGNE JEAN-MICHEL , JULEMONT FABIEN , DE LEVAL XAVIER
IPC分类号： C07D213/00 , A61K31/44 , A61P29/00 , A61P43/00 , C07D213/76 , C07D213/89
摘要： New pyridinic sulfonamide derivatives represented by a general formula (I), wherein R~1, represents a mono- or polyhalogenated C~l-12-alkyl or a mono- o r poly-halogenated C~3-8-cycloalkyl group. The method of production of such derivatives and their use as active therapeutic substance in the treatment o f diseases such as inflammation, arthrosis, cancer, angiogenesis and asthma ar e also reported.

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