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1. 发明公开

KR20120031202A Composition for treatment or prevention of colitis 审中-公开
标题翻译：用于治疗或预防住院的组合物
公开(公告)号：KR20120031202A
公开(公告)日：2012-03-30
申请号：KR20120018764
申请日：2012-02-24
申请人： UNIV KYUNG HEE UNIV IND COOP GROUP
发明人： KIM DONG HYUN , HAN MYUNG JOO , JOH EUN HA , LEE IN AH
IPC分类号： A61K31/56 , A61K36/344 , A61P1/00
CPC分类号： A61K31/704 , A23L29/035 , A61K31/192 , A61K31/194 , A61K36/344 , A61K2236/19 , Y10S514/886
摘要： PURPOSE: A composition for treating or preventing colitis including the saponin is provided to control IL-1 beta, IL-6, and expression of tumor necrosis factor alpha, thereby effective for colitis treatment. CONSTITUTION: A composition for treating or preventing colitis comprises lancemacide X, echinocystic acid 3-O-β-Dglucuronopyranoside: EAG, or saponin of echinocystic acid as an active ingredient. The saponin is isolated from Condonopsis lanceolata Trautv fermentation product. The colitis is either ulcerative colitis or Crohn's disease. The pharmaceutical composition for colitis treatment or prevention comprises codonopsis lanceolata which includes Condonopsis lancemacide X, echinocystic acid 3-O-β-Dglucuronopyranoside: EAG, or saponin of echinocystic acid as the active ingredient. The fermentation product is obtained by extracting of codonopsis lanceolata after fermentating or fermentating codonopsis lanceolata extracts. The fermentation is lactobacillus fermentation. A food composition for colitis improvement or prevention comprises Condonopsis lancemacide X, echinocystic acid 3-O-β-Dglucuronopyranoside: EAG, or saponin of echinocystic acid as the active ingredient.
摘要翻译：目的：提供治疗或预防包括皂苷在内的结肠炎的组合物，以控制IL-1β，IL-6和肿瘤坏死因子α的表达，从而有效治疗结肠炎。构成：用于治疗或预防结肠炎的组合物，其包含杀虫剂X，棘球绦虫酸酯3-E-D-谷氨酰吡喃糖苷，EAG或皂角苷作为活性成分。皂甙与Condonopsis lanceolata Trautv发酵产物分离。结肠炎是溃疡性结肠炎或克罗恩病。用于结肠炎治疗或预防的药物组合物包括密码子披针菇，其包括放线菌素Lancemacide X，棘球囊虫酸3-O-β-D-葡萄糖醛酸吡喃糖苷：EAG或棘球ic酸的皂苷作为活性成分。发酵产物通过在发酵或发酵密码子提取物后提取密码子来获得。发酵是乳杆菌发酵。用于结肠炎改善或预防的食物组合物包括放线菌素Lancemacide X，棘球囊酸3-O-β-D-葡萄糖醛酸吡喃糖苷：EAG或棘球ic酸的皂角苷作为活性成分。

2. 发明公开

KR20120026588A Composition for prevention or treatment of cancer or hiv 审中-公开
标题翻译：预防或治疗癌症或艾滋病毒的组合物
公开(公告)号：KR20120026588A
公开(公告)日：2012-03-19
申请号：KR20120018829
申请日：2012-02-24
申请人： UNIV KYUNG HEE UNIV IND COOP GROUP
发明人： KIM DONG HYUN , HAN MYUNG JOO , JOH EUN HA , KIM YU RI
IPC分类号： A61K31/7048 , A61K31/365 , A61P31/18
CPC分类号： A61K31/365 , A23L29/035 , A23V2200/322 , A23V2200/324 , A61K31/7048 , Y10S514/885
摘要： PURPOSE: A composition for preventing or treating cancer or HIV is provided to treat and/or prevent cancer, HIV infectious diseases, HIV dementia, or HIV neural cell injury. CONSTITUTION: A pharmaceutical composition for preventing or treating HIV infectious diseases, AIDS, HIV dementia, or HIV neural cell injury contains arctigenin or arctinin as an active ingredient. The HIV infectious diseases are a macrophage or microglia cell infectious disease. A pharmaceutical composition for preventing or treating cancer contains artinin as an active ingredient.
摘要翻译：目的：提供用于预防或治疗癌症或HIV的组合物，用于治疗和/或预防癌症，HIV感染性疾病，HIV痴呆或HIV神经细胞损伤。构成：用于预防或治疗艾滋病毒感染性疾病，艾滋病，艾滋病毒痴呆或HIV神经细胞损伤的药物组合物含有作为活性成分的弓形虫素或抗坏血酸蛋白酶。 HIV感染性疾病是巨噬细胞或小胶质细胞感染性疾病。用于预防或治疗癌症的药物组合物含有artinin作为活性成分。

3. 发明公开

KR20120005896A Composition for treatment or prevention of colitis 有权
标题翻译：用于治疗或预防住院的组合物
公开(公告)号：KR20120005896A
公开(公告)日：2012-01-17
申请号：KR20100066589
申请日：2010-07-09
申请人： UNIV KYUNG HEE UNIV IND COOP GROUP
发明人： KIM DONG HYUN , HAN MYUNG JOO , JOH EUN HA , LEE IN AH
IPC分类号： A61K31/56 , A61K36/424 , A61K36/48 , A61P1/04
CPC分类号： A61K31/704 , A23L29/035 , A61K31/047 , A61K36/25 , A61K36/344 , A61K36/424 , A61K36/48 , A61K2236/19 , Y10S514/886
摘要： PURPOSE: A pharmaceutical composition containing saponin is provided to effectively prevent or treat colitis. CONSTITUTION: A pharmaceutical composition for preventing or treating colitis contains saponin as an active ingredient, including soyasaponin I, soyasaponin Ab[3-O-beta-D-glucopyranosyl-(1→2)-beta-Dgalactopyranosyl-(1→2)-O-beta-D-glucuronopyranosyl, 22-O-beta-D-2,3,4,6-tetra acetyl-glucopyranosyl (1→2)-alpha-L-arabinopyranosyl soyasapogenol A], soyasapogenol A, soyasapogenol B, gypenoside LXXIV, gypenoside XLV, TN-2[2alpha,3beta,20(S)-trihydroxydammar-24-ene-20-O-[alpha-L-rhamnosyl (1→6)-beta-D-glucopyranoside], kalopanaxsaponin H, kalopanaxsaponin B, kalopanaxsaponin A, lancemacide X, echinocystic acid 3-O-beta-Dglucuronopyranoside, or echinocystic acid. The sponin is isolated from extract or fermentation of soybean, bean sprout, Gynostemma pentaphyllum, kalopanacis Cortex, or Condonopsis lanceolata Trautv. The colitis includes UC(ulcerative colitis) or Crohn's disease(CD). The pharmaceutical composition also contains the extract or fermentation as an active ingredient.
摘要翻译：目的：提供含有皂苷的药物组合物，有效预防或治疗结肠炎。构成：用于预防或治疗结肠炎的药物组合物含有皂苷作为活性成分，包括大豆皂苷I，大豆皂苷Ab [3-O-β-D-吡喃葡萄糖基 - （1→2）-β-半乳糖吡喃糖基 - （1→2） - O-β-D-葡萄糖醛酸吡喃糖基，22-O-β-D-2,3,4,6-四乙酰 - 吡喃葡萄糖基（1→2）-alpha- L-阿拉伯吡喃糖基大豆皂甙A]，大豆皂甙元A，大豆皂甙元B， LXXIV，gypenoside XLV，TN-2 [2α，3β，20（S） - 三氢羟基-24-烯-20-O- [α-L-鼠李糖基（1→6）-β-D-吡喃葡萄糖苷]，kalopanaxsaponin H， kalopanaxsaponin B，kopopanaxsaponin A，氯磺草胺X，棘球囊酸3-O-β-D-葡萄糖醛酸吡喃糖苷或棘球囊酸。从大豆，豆芽，绞股蓝，绞股蓝皮质或绞股蓝提取物的提取物或发酵中分离出来。结肠炎包括UC（溃疡性结肠炎）或克罗恩氏病（CD）。药物组合物还含有提取物或发酵作为活性成分。

4. 发明公开

KR20120031203A Composition for prevention or treatment of cancer or hiv 有权
标题翻译：预防或治疗癌症或艾滋病毒的组合物
公开(公告)号：KR20120031203A
公开(公告)日：2012-03-30
申请号：KR20120018831
申请日：2012-02-24
申请人： UNIV KYUNG HEE UNIV IND COOP GROUP
发明人： KIM DONG HYUN , HAN MYUNG JOO , JOH EUN HA , KIM YU RI
IPC分类号： A61K31/352 , A61P31/18 , A61P35/00
摘要： PURPOSE: A composition for treating or preventing human immunodeficiency virus(HIV) is provided to treat or prevent human immunodeficiency virus(HIV) infection, and HIV dementia. CONSTITUTION: A composition for treating or preventing human immunodeficiency virus(HIV) comprises tangeretin, nobiletin, apigenin, or kaempherol as an active ingredient. The human immunodeficiency virus infection is a latent human immunodeficiency virus infection. The human immunodeficiency virus infection is either cell infection of macrophage or microglia cell. A food composition for treating and preventing cancer comprises tangeretin, nobiletin, apigenin, or kaempherol as an active ingredient.
摘要翻译：目的：提供用于治疗或预防人类免疫缺陷病毒（HIV）的组合物，用于治疗或预防人类免疫缺陷病毒（HIV）感染和HIV痴呆。构成：用于治疗或预防人体免疫缺陷病毒（HIV）的组合物，其中包括作为活性成分的正德宁，诺贝利，芹菜素或山奈酚。人类免疫缺陷病毒感染是潜在的人类免疫缺陷病毒感染。人体免疫缺陷病毒感染是巨噬细胞或小神经胶质细胞的细胞感染。用于治疗和预防癌症的食物组合物包括作为活性成分的正德宁，诺贝利蛋白，芹菜素或山奈酚。

5. 发明公开

KR20150097442A Composition comprising extracts of Codonopsis lanceolata or compounds isolated therefrom for preventing, improving or treating obesity or obesity-related disease 有权
标题翻译：包含用于预防，改善或治疗肥胖或与肥胖有关的疾病的分离物的番茄红素或其化合物的提取物的组合物
公开(公告)号：KR20150097442A
公开(公告)日：2015-08-26
申请号：KR20150105809
申请日：2015-07-27
申请人： UNIV KYUNG HEE UNIV IND COOP GROUP
发明人： HAN MYUNG JOO , KIM DONG HYUN , CHUNG JA YONG
IPC分类号： A61K31/015 , A23L1/30 , A61K31/70 , A61K31/702 , A61K36/344
摘要： 본 발명은 발효 더덕 추출물, 란세마사이드 A(lancemaside A), 에키노사이스틱산(echinocystic acid) 및 이들의 약학적 또는 식품학적으로 허용가능한 염으로 이루어진 군에서 선택되는 1종 이상을 유효 성분으로 포함하는 비만 또는 비만 관련 질환의 예방, 개선 또는 치료용 조성물을 제공한다. 본 발명에 따른 발효 더덕 추출물, 란세마사이드 A(lancemaside A), 에키노사이스틱산(echinocystic acid) 등은 약학 조성물 또는 기능성 식품 조성물을 구성하는 식의약적 소재로 사용될 수 있다. 특히, 본 발명에 따른 란세마사이드 A(lancemaside A), 에키노사이스틱산(echinocystic acid)은 AMPK(AMP-activated protein kinase)를 활성화시키고 지방합성 관련 유전자의 발현을 하향 조절시키기 때문에 전구지방세포의 지방세포로의 분화시 분화를 억제하는 효과 및 중성지질의 축적을 억제하는 효과가 우수하다.
摘要翻译：在本发明中提供的是含有选自由发酵的党参（Pseudopopsis）披针丝提取物（lantmaside A），棘
果虫酸（echinocystic acid）以及药学或细胞学上可接受的盐组成的组中的一种或多种组合物作为预防或治疗肥胖或肥胖相关的活性成分疾病。根据本发明的这种发酵的党参紫杉醇提取物，蓝假丁酸酯A和棘皮囊酸可以用作构成药物组合物或功能性食品组合物的食品和药物成分。特别地，根据本发明的发酵党参披针叶提取物（lantmaside A）和棘球绦虫酸（echinocystic acid）活化AMP-活化蛋白激酶（AMPK），降低脂肪生成相关基因的表达，从而具有极好的抑制前脂肪细胞分化的作用脂肪细胞和抑制中性脂质积累的作用。

6. 发明公开

KR20120031037A Composition for prevention or treatment of cancer or hiv 审中-公开
标题翻译：预防或治疗癌症或艾滋病毒的组合物
公开(公告)号：KR20120031037A
公开(公告)日：2012-03-29
申请号：KR20120018830
申请日：2012-02-24
申请人： UNIV KYUNG HEE UNIV IND COOP GROUP
发明人： KIM DONG HYUN , HAN MYUNG JOO , JOH EUN HA , KIM YU RI
IPC分类号： A61K31/704 , A61K31/70 , A61P31/00 , A61P31/18
CPC分类号： A61K31/704 , A23L29/035 , A23V2200/324 , Y10S514/885
摘要： PURPOSE: A composition for treating or preventing cancer or human immunodeficiency virus(HIV) is provided to inhibit AKT activation, suppress phosphoinisitide 3-kinase(PI3K), and beta activate glycogen synthase kinase 3 beta(GSK3). CONSTITUTION: A composition for treating or preventing human immunodeficiency virus(HIV), HIV infection, HIV dementia, and cancer comprises kalopanaxsaponin A as an active ingredient. The human immunodeficiency virus infection is a latent infection. The human immunodeficiency virus infection is macrophage or microglia cell infection. A food composition for treating and preventing HIV infection, acquired immune deficiency syndrome(AIDS), HIV nerve cell damage, and HIV dementia comprises kalopanaxsaponin A as an active ingredient. A pharmaceutical composition for treating and preventing cancer comprises kalopanaxsaponin A as an active ingredient. A food composition for treating and preventing cancer comprises kalopanaxsaponin A as an active ingredient.
摘要翻译：目的：提供一种用于治疗或预防癌症或人类免疫缺陷病毒（HIV）的组合物，用于抑制AKT活化，抑制磷酸西来肽3-激酶（PI3K）和β激活糖原合酶激酶3β（GSK3）。构成：用于治疗或预防人类免疫缺陷病毒（HIV），HIV感染，艾滋病毒痴呆和癌症的组合物包括喀土坡素A作为活性成分。人体免疫缺陷病毒感染是一种潜伏感染。人体免疫缺陷病毒感染是巨噬细胞或小胶质细胞感染。用于治疗和预防HIV感染，获得性免疫缺陷综合征（AIDS），HIV神经细胞损伤和HIV痴呆的食物组合物包括作为有效成分的喀喇昆仑皂甙A. 用于治疗和预防癌症的药物组合物包括作为活性成分的喀喇昆仑皂甙A. 用于治疗和预防癌症的食物组合物包括作为有效成分的喀喇昆仑皂甙A.

7. 发明公开

KR20120027042A Composition for treatment or prevention of colitis 有权
标题翻译：用于治疗或预防住院的组合物
公开(公告)号：KR20120027042A
公开(公告)日：2012-03-20
申请号：KR20120018763
申请日：2012-02-24
申请人： UNIV KYUNG HEE UNIV IND COOP GROUP
发明人： KIM DONG HYUN , HAN MYUNG JOO , JOH EUN HA , LEE IN AH
IPC分类号： A61K31/704 , A61K36/25 , A61P35/00
CPC分类号： A61K31/704 , A23L29/035 , A23V2200/32 , A61K36/25 , Y10S514/886 , Y10S514/925
摘要： PURPOSE: A pharmaceutical composition containing saponin for preventing or treating colitis and a food composition are provided. CONSTITUTION: A pharmaceutical composition for preventing or treating colitis contains saponin of kalopanaxsaponin H, kalopanaxsaponin B, or kalopanaxsaponin A as an active ingredient. The saponin is isolated from Kalopanacis Cortex extracts or fermentation. The colitis includes ulcerative colitis or Crohn's disease. A pharmaceutical composition for preventing or treating colitis contains kalopanaxsaponin H, kalopanaxsaponin B, or kalopanaxsaponin A as an active ingredient.
摘要翻译：目的：提供含有皂苷的药物组合物，用于预防或治疗结肠炎和食物组合物。构成：用于预防或治疗结肠炎的药物组合物含有卡波菌素H皂甙皂甙皂甙皂甙皂甙B或胭脂虫素A皂甙A作为活性成分。皂角苷分离自卡拉帕拉西斯皮草提取物或发酵。结肠炎包括溃疡性结肠炎或克罗恩氏病。用于预防或治疗结肠炎的药物组合物含有作为有效成分的卡波帕他皂甙H，胭脂红onin素B或胭脂红s素A.

8. 发明专利

CA2910250A1 COMPOSITION FOR PREVENTING, IMPROVING OR TREATING COLITIS INCLUDING COMBINED EXTRACTS 未知
公开(公告)号：CA2910250A1
公开(公告)日：2014-10-30
申请号：CA2910250
申请日：2014-02-17
申请人： UNIV KYUNG HEE UNIV IND COOP GROUP
发明人： KIM DONG HYUN , HAN MYUNG JOO
IPC分类号： A61K36/8964 , A61K31/70 , A61K36/718 , A61P1/00
摘要： The present invention relates to a novel use of an Anemarrhena asphodeloides root extract and the like, and a Rhizoma Coptidis extract and the like, and specifically, provides a composition for preventing, relieving or treating colitis, containing, as active ingredients: at least one selected from the Anemarrhena asphodeloides rootextract, an alcohol-soluble fraction of the Anemarrhena asphodeloides rootextract having a carbon number of 3 to 8, mangiferin, a pharmaceutically acceptable salt of mangiferin, neomangiferin, or a pharmaceutically acceptable salt of neomangiferin; and at least one selected from the Rhizoma Coptidis extract or an alcohol-soluble fraction of the Rhizoma Coptidis extract having a carbon number of 3 to 8. According to the present invention, complex extracts comprising the Anemarrhena asphodeloides root extract and the like, and the Rhizoma Coptidis extract and the like can have excellent prevention or treatment activity against colitis in animal models, and thus can be used as ingredients for food and pharmaceutical use provided to a pharmaceutical composition or a functional food composition.

9. 发明专利

HK1212387A1 LACTIC ACID BACTERIA CAPABLE OF PREVENTING AND OR TREATING SENESCENCE AND DEMENTIA 未知
公开(公告)号：HK1212387A1
公开(公告)日：2016-06-10
申请号：HK16100354
申请日：2016-01-13
申请人： UNIV KYUNG HEE UNIV IND COOP GROUP
发明人： KIM DONG-HYUN , HAN MYUNG JOO , JUNG IL-HOON , JUNG MYUNG-AH
IPC分类号： C12N20060101 , A23L33/00 , A61K35/747 , A61P20060101 , C12R20060101
摘要： The present invention provides a novel lactic acid bacterium having antioxidant and anti-aging functions and a dementia alleviation effect, and more specifically, provides Lactobacillus pentosus var. plantarum C29 KCCM11291P and Lactobacillus curvatus C3 KCCM430009. In addition, the present invention provides an antioxidant and anti-aging pharmaceutical composition and a dietary supplement containing the Lactobacillus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009 of the present invention as an active ingredient, and a composition for preventing or treating dementia and a dietary supplement for preventing or alleviating dementia, containing Lactobacillus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009 as an active ingredient. Additionally, the present invention provides a composition for preventing or treating dementia, containg a fermentation composition, as an active ingredient, fermented by Lactobacullus pentosus var. plantarum C29 KCCM11291P or Lactobacillus curvatus C3 KCCM430009.

10. 发明专利

AU2014258204A1 Composition for preventing, relieving or treating colitis, containing complex extracts 未知
公开(公告)号：AU2014258204A1
公开(公告)日：2015-11-12
申请号：AU2014258204
申请日：2014-02-17
申请人： UNIV KYUNG HEE UNIV IND COOP GROUP
发明人： KIM DONG HYUN , HAN MYUNG JOO
IPC分类号： A61K36/8964 , A61K31/70 , A61K36/718 , A61P1/00
摘要： The present invention relates to a novel use of an

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