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1. 发明申请

WO2012039137A2 A NUCLEIC ACID HAVING AN ANTI-METABOLIC SYNDROME EFFECT 审中-公开
标题翻译：一种具有抗代谢综合症效应的核酸
公开(公告)号：WO2012039137A2
公开(公告)日：2012-03-29
申请号：PCT/JP2011005325
申请日：2011-09-21
申请人： UNIV HOKKAIDO NAT UNIV CORP , SHIONOGI & CO , MITSUTAKE SUSUMU , ZAMA KOTA , IGARASHI YASUYUKI , YOSHIDA TETSUYA , TANAKA YOSHIKAZU , TAKEMOTO HIROSHI
发明人： MITSUTAKE SUSUMU , ZAMA KOTA , IGARASHI YASUYUKI , YOSHIDA TETSUYA , TANAKA YOSHIKAZU , TAKEMOTO HIROSHI
IPC分类号： C12N15/113 , A61K31/712 , A61K31/713
CPC分类号： C12N15/1137 , C12N2310/11 , C12N2310/14 , C12N2310/3231 , C12Y207/08
摘要： The problem of the present invention is to prove a medicament for decreasing body weight, a medicament for decreasing visceral fat, a medicament for decreasing triglyceride in the liver, and a method for screening a medicament for ameliorating obesity and fatty liver. The problem is solved by a method comprising measuring an activity of a candidate material for inhibiting a sphingomyelin synthetase wherein if the candidate material has an activity for inhibiting a sphingomyelin synthetase, the candidate material is judged to have at least one function selected from the consisting of an anti-obesity drug, a drug for decreasing visceral fat, a drug for treating fatty liver and an agent for increasing adiponectin expression.
摘要翻译：本发明的课题在于，提供一种降低体重的药物，降低内脏脂肪的药物，降低肝脏甘油三酯的药物及筛选改善肥胖和脂肪肝的药物的方法。该问题通过包括测定用于抑制鞘磷脂合成酶的候选物质的活性的方法来解决，其中如果候选物质具有抑制鞘磷脂合成酶的活性，则判断候选物质具有选自以下的至少一种功能：抗肥胖药物，减少内脏脂肪的药物，治疗脂肪肝的药物和增加脂联素表达的药物。

2. 发明公开

EP2481808A4 AMELIORATION OF METABOLIC SYNDROME OR METHOD FOR SCREENING FOR AMELIORATING AGENT FOR METABOLIC SYNDROME UTILIZING PHYSIOLOGICAL FUNCTION OF SPHINGOMYELIN SYNTHASE SMS2 审中-公开
标题翻译：代谢综合征或方法，以筛选缓解代谢综合征救济资金使用鞘磷脂合成酶SMS2生理功能
公开(公告)号：EP2481808A4
公开(公告)日：2013-04-10
申请号：EP10818555
申请日：2010-09-22
申请人： UNIV HOKKAIDO NAT UNIV CORP , SHIONOGI & CO
发明人： MITSUTAKE SUSUMU , IGARASHI YASUYUKI , ZAMA KOTA , YOSHIDA TETSUYA , TANAKA YOSHIKAZU , TAKEMOTO HIROSHI
IPC分类号： C12Q1/48 , C12N5/10 , C12N15/09 , G01N33/15 , G01N33/50 , G01N33/68
CPC分类号： C12Q1/48 , G01N2333/9129 , G01N2800/044

3. 发明专利

JPH08316723A SPHERICAL WAVE RADIATING DIELECTRIC ANTENNA SYSTEM USING DIELECTRIC 1/4 WAVELENGTH EXCITING ANTENNA 失效
公开(公告)号：JPH08316723A
公开(公告)日：1996-11-29
申请号：JP12190695
申请日：1995-05-19
申请人： MIZUTANI PURINTEKUSU KK , TAKEMOTO HIROSHI
发明人： TAKEMOTO HIROSHI
IPC分类号： H01Q9/30
摘要： PURPOSE: To obtain a spherical wave radiating antenna system suitable for various radio equipments for UHF to quasi-giga band. CONSTITUTION: The spherical wave radiating antenna system has a dielectric 1/4 wavelength exciting antenna ANT, a board 1 with a throughhole 2 with a throughhole electrode 3 to which the antenna is inserted and connected and with a ground conductor 5, and a matching conductor 7 connected with the board. The dielectric 1/4 wavelength exciting antenna ANT is surrounded by an antenna cap 9.

4. 发明专利

JPS5836842B2 失效
公开(公告)号：JPS5836842B2
公开(公告)日：1983-08-12
申请号：JP8080878
申请日：1978-07-03
申请人： MIZUTANI PURINTEKUSU KK , TAKEMOTO HIROSHI
发明人： TAKEMOTO HIROSHI
IPC分类号： H01Q1/12 , H01Q9/30 , H01Q9/32 , H01Q21/00 , H01Q21/20

5. 发明专利

JPS558145A JJTYPE ANTENNA 失效
公开(公告)号：JPS558145A
公开(公告)日：1980-01-21
申请号：JP8080878
申请日：1978-07-03
申请人： MIZUTANI PURINTEKUSU KK , TAKEMOTO HIROSHI
发明人： TAKEMOTO HIROSHI
IPC分类号： H01Q1/12 , H01Q9/30 , H01Q9/32 , H01Q21/00 , H01Q21/20
摘要： PURPOSE:To secure an easy matching even with a big change of the antenna capacity with installation of the arrester circuit as well as the vertical attachment of both the radiation element of 3/4 wavelength and the matching element of 1/4 wavelength onto the metal basement to be earthed. CONSTITUTION:Both radiation element 29 of 3/4 wavelength and matching element 34 of 1/4 wavelength formed with the metal pipe of an appropriate diameter are attached vertically onto earthed metal basement 30 with a constant parallel space kept between the two elements. At the same time, feed matching element 31 and 34 formed by the metal pipe are attached to basement 30 via insulator 32 and a parallel space secured between. Furthermore, element 34 is attached to circular arc type slit 33 centering on element 29 formed on basement 30 via nut 35 in such way that the space can be adjusted to element 31. In such constitution, the steady non- directive radiation of the vertically polarization is obtained at the area of 1/2 wavelength of element 29. In addition, the degree of lightning arrest is increased since element 29 and 34 can be attached directly onto basement 30.

6. 发明专利

JPS5358746A POLYGONAL CAGE ANTENNA 失效
公开(公告)号：JPS5358746A
公开(公告)日：1978-05-26
申请号：JP13395076
申请日：1976-11-08
申请人： TAKEMOTO HIROSHI
发明人： TAKEMOTO HIROSHI
IPC分类号： H01Q9/40 , H01Q1/34

7. 发明专利

JPH0853191A BOTTLE OPENER 失效
公开(公告)号：JPH0853191A
公开(公告)日：1996-02-27
申请号：JP21648094
申请日：1994-08-08
申请人： TAKEMOTO HIROSHI
发明人： TAKEMOTO HIROSHI
IPC分类号： B67B7/15
摘要： PURPOSE:To obtain a bottle opener for easily taking a tight cap off a bottle. CONSTITUTION:Four parts 1 are provided, each of which has a nonslip device 2 on the inner side and screw parts 3 consisting of a projection and a hollow. A bottle opener is formed in a square by combining the four sets of projections and hollows respectively. The bottle opener can be formed freely into a rhombus by diagonally (A versus C, B versus D) tightening it to fit the size of a cap so that a cap of any size can be gripped in it. The bottle opener is fitted around a cap freely by hand and tuned counterclockwise; then the cap even when extremely tight can be loosened in a simple manner.

8. 发明专利

JPH0826299A DEVICE FOR OPENING SHOPPING AND TRASH BAG 失效
公开(公告)号：JPH0826299A
公开(公告)日：1996-01-30
申请号：JP19267494
申请日：1994-07-13
申请人： TAKEMOTO HIROSHI
发明人： TAKEMOTO HIROSHI
IPC分类号： B65B43/26 , B65D33/00
摘要： PURPOSE:To easily open a new bag by providing nonslips on the tying part of a shopping and trash bag. CONSTITUTION:Nonslips 4 are provided at the tying parts 5 of the shopping and trash bags of polyethylene, etc. used in a large amount at a supermarket, etc. Specifically, the nonslips 4 are applied over both the side edges of the two tying parts 5 in close contact in such a manner as to bring the bulb of a finger at the first joint into contact with the nonslips from both the sides of the tying parts. When the two nonslip parts of the tying parts are rubbed against each other with the fingers, the two tying parts in close contact are slided apart in opposite directions, so that the bag can be easily opened. Concerning the formation of the nonslip 4, its thin layer is attached to the tying parts 5 via an adhesive agent of a thin layer or the tying parts are sprayed with a rapid cure nonslip agent. In this way even the mouth of the shopping or trash bag of the material high in adsorptivity and superthin in thickness can be easily opened by anybody without being moistened with a wet towel or being licked.

9. 发明专利

JPH0774531A ANTENNA DEVICE FOR BIDIRECTIONAL SIMULTANEOUS COMMUNICATION USING DIELECTRIC QUARTER WAVELENGTH EXCITATION ANTENNA 失效
公开(公告)号：JPH0774531A
公开(公告)日：1995-03-17
申请号：JP22024593
申请日：1993-09-03
申请人： MIZUTANI PURINTEKUSU KK , TAKEMOTO HIROSHI
发明人： TAKEMOTO HIROSHI
IPC分类号： H01Q9/30
摘要： PURPOSE:To obtain an antenna device which is suitable to a bidirectional simultaneous communication device by arranging the transmission antenna and the reception antenna of a dielectric quarter wavelength excitation antenna by making the antennas approach by a prescribed distance. CONSTITUTION:A dielectric quarter wavelength excitation antenna ANT-TX for transmission having a resonance frequency within a transmission frequency band is electrically connected with the contact plug 2 of an insulating box 1 and is mechanically fixed. In the same way, a dielectric quarter wavelength excitation antenna ANT-RX for reception having the resonance frequency within a reception frequency band is electrically connected with the contact plug 2' and is mechanically fixed. The transmission antenna ANT-TX and the reception antenna ANT-RX are arranged by making the antennas approach by the distance by which a desired standing wave ratio can be obtained in the transmission frequency band and the reception frequency band. By this constitution, the frequency characteristics of the antennas ANT-TX and ANT-RX changes to have wider bands, and wide transmission band width and reception band width can be obtained.

10. 发明专利

JPH0774530A DIELCTRIC QUARTER WAVELENGTH EXCITATION WAVEGUIDE BODY ANTENNA DEVICE 失效
公开(公告)号：JPH0774530A
公开(公告)日：1995-03-17
申请号：JP22024193
申请日：1993-09-03
申请人： MIZUTANI PURINTEKUSU KK , TAKEMOTO HIROSHI
发明人： TAKEMOTO HIROSHI
IPC分类号： H01Q9/30
摘要： PURPOSE:To obtain an antenna device whose beam widths not only in a horizontal direction but also in a vertical direction are large and which is small-sized and light in weight by providing a waveguide body and a matching conductor. CONSTITUTION:When a waveguide body 5 is located in the almost spherical electric field formed by a dielectric quarter wavelength excitation antenna ANT, high frequency current is flowed to the inner peripheral surface of the waveguide body 5. The high frequency current is flowed also to the outer peripheral surface of the waveguide body 5, an electric field is generated in a right angle direction to the magnetic field generated on an outer peripheral surface and the electric field is radiated as an electromagnetic wave. The part of the electric field is reflected by the inner peripheral surface, resonance energy is increased by concentrating on the antenna and the electric field itself generated from the antenna is intensified. Further, a radiation electric field is enlarged to the whole vertical direction and a vertical radiation pattern becomes a cocoon shape. A conductor 6 which is electrically connected with the waveguide body 5 and extending in the opposite direction to the antenna and in parallel with a power feeding body 1 is provided, the unbalance of the flouing of high frequency current is eliminated and the antenna ANT is made to be matched.

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