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1. 发明申请

WO2012041867A3 COMBINED ANTIGEN AND DNA VACCINE FOR PREVENTING AND TREATING AUTOIMMUNE DISEASES 审中-公开
标题翻译：用于预防和治疗自身免疫性疾病的联合抗生素和DNA疫苗
公开(公告)号：WO2012041867A3
公开(公告)日：2012-06-07
申请号：PCT/EP2011066797
申请日：2011-09-27
申请人： UNIV CHINA AGRICULTURAL , LEONARD THOMAS CHARLES , WANG BIN , GENG SHUANG , JIN JIN
发明人： WANG BIN , GENG SHUANG , JIN JIN
IPC分类号： A61K39/00 , A61K39/35 , A61K48/00
CPC分类号： A61K39/35 , A61K39/0008 , A61K2039/53
摘要： The present invention relates to treating and preventing symptoms of an allergy, asthma, an autoimmune disease, and transplant rejection using a combination vaccine containing an antigen and a DNA encoding the antigen.
摘要翻译：本发明涉及使用含有抗原和编码抗原的DNA的组合疫苗来治疗和预防过敏症，哮喘，自身免疫性疾病和移植排斥的症状。

2. 发明申请

WO2007076084A3 ALLERGY INHIBITOR COMPOSITIONS AND KITS AND METHODS OF USING THE SAME 审中-公开
标题翻译：过敏抑制剂组合物和用途及其使用方法
公开(公告)号：WO2007076084A3
公开(公告)日：2008-12-24
申请号：PCT/US2006049161
申请日：2006-12-22
申请人： UNIV CHINA AGRICULTURAL , WYETH CORP , WANG BIN , JIN HUALI , KANG YOUMIN , CHU HSIEN-JUE , NG KALEUNG
发明人： WANG BIN , JIN HUALI , KANG YOUMIN , CHU HSIEN-JUE , NG KALEUNG
IPC分类号： A61K39/00 , A61K39/02 , A61K39/12 , A61K39/36 , A61K39/385 , A61K39/395
CPC分类号： A61K39/35 , A61K39/0003 , A61K39/0005 , A61K39/0008 , A61K2039/53 , A61K2039/57
摘要： Compositions and kits for inhibiting an allergic response against an allergenic protein are disclosed. The compositions comprise a eukaryotic cell expression vector containing nucleotide sequences encoding an allergenic protein or a polypeptide that comprises an antigenic epitope of said allergenic protein; and an allergenic protein or a polypeptide that comprises an antigenic epitope of the allergenic protein. The kits comprise a first container which comprises a eukaryotic cell expression vector containing nucleotide sequences encoding an allergenic protein or a polypeptide that comprises an antigenic epitope of the allergenic protein and a second container which comprises an allergenic protein or a polypeptide that comprises an antigenic epitope of said allergenic protein. Compositions and kits for inhibiting an allergic response against an flea allergenic protein; a feline allergenic protein; a canine allergenic protein; a dust mite allergenic protein; a peanut allergenic protein; a Japanese cedar allergenic protein; and a blomia tropicalis allergenic protein are disclosed. Methods if using such compositions and kits are also disclosed.
摘要翻译：公开了抑制对变应原性蛋白质的过敏反应的组合物和试剂盒。所述组合物包含含有编码过敏原蛋白或包含所述变应原蛋白的抗原表位的多肽的核苷酸序列的真核细胞表达载体; 以及包含过敏原蛋白的抗原表位的过敏原蛋白或多肽。所述试剂盒包括第一容器，其包含含有编码过敏原蛋白的核苷酸序列的真核细胞表达载体或包含过敏原蛋白的抗原表位的多肽，第二容器包含过敏原蛋白或包含抗原表位的多肽说过敏性蛋白质。用于抑制针对跳蚤过敏原蛋白质的过敏反应的组合物和试剂盒; 猫过敏原蛋白; 犬过敏蛋白; 尘螨过敏原蛋白; 花生过敏蛋白; 日本雪松过敏蛋白; 并且公开了热带炎热带炎性过敏蛋白。还公开了使用这些组合物和试剂盒的方法。

3. 发明公开

EP3106174A4 IMMUNOTHERAPEUTIC COMPOSITION, THERAPEUTIC METHOD AND DIAGNOSTIC METHOD 审中-公开
标题翻译： IMMUNTHERAPEUTISCHE ZUSAMMENSETZUNG，THERAPEUTISCHES VERFAHREN UND DIAGNOSEVERFAHREN
公开(公告)号：EP3106174A4
公开(公告)日：2017-08-09
申请号：EP15749159
申请日：2015-02-10
申请人： WANG BIN , JIN JIN , XIE XIAOPING , HE ZHONGHUAI , YU QINGLING , BEIJING ADVACCINE BIOTECHNOLOGY CO LTD
发明人： WANG BIN , JIN JIN , XIE XIAOPING , HE ZHONGHUAI , YU QINGLING
IPC分类号： A61K38/20 , A61P31/16
CPC分类号： A61K38/20 , A61K39/145 , A61K48/00 , A61K2039/55527 , C12N2760/16134 , G01N33/6869 , G01N2333/11 , G01N2333/54 , G01N2800/26

4. 发明专利

AU2018200638A1 Immunotherapeutic composition, therapeutic method and diagnostic method 未知
公开(公告)号：AU2018200638A1
公开(公告)日：2018-03-08
申请号：AU2018200638
申请日：2018-01-25
申请人： BEIJING ADVACCINE BIOTECHNOLOGY CO LTD , HE ZHONGHUAI , JIN JIN , WANG BIN , XIE XIAOPING , YU QINGLING
发明人： JIN JIN , XIE XIAOPING , WANG BIN , YU QINGLING , HE ZHONGHUAI
IPC分类号： A61K38/20 , A61P31/16
摘要： Disclosed herein is a immunotherapeutic composition comprising IL-17. Also disclosed herein is a method of increasing an immune response in a subject in need thereof. The method may include administering the immunotherapeutic composition to the subject. The increased immune response may protect against an influenza virus. Further disclosed herein is a method of diagnosing influenza viral infection. Sheet 1/14 -750 -*H5NI +0.5pg/mI rlL-17A 0.1pg/ml rIL-17A*IL-17A KO 100. 0, 0 A 124 1 Days * -9 4-4£ -J 0 H5N1 + + + IL-17AKO rIL-17A

5. 发明专利

CA2937970A1 IMMUNOTHERAPEUTIC COMPOSITION, METHOD OF TREATMENT, AND METHOD OF DIAGNOSIS 未知
公开(公告)号：CA2937970A1
公开(公告)日：2015-08-20
申请号：CA2937970
申请日：2015-02-10
申请人： YU QINGLING , WANG BIN , JIN JIN , XIE XIAOPING , HE ZHONGHUAI , BEIJING ADVACCINE BIOTECHNOLOGY CO LTD
发明人： YU QINGLING , WANG BIN , JIN JIN , XIE XIAOPING , HE ZHONGHUAI
IPC分类号： A61K38/20 , A61P31/16
摘要： Disclosed is an immunotherapeutic composition comprising IL-17. Also disclosed is a method of increasing the required immune response of subjects. The method can comprise applying the immunotherapeutic composition to subjects. The increased immune response can protect against flu virus. Further disclosed is a method of diagnosing flu virus infection.

6. 发明专利

AU2015218098A1 Immunotherapeutic composition, therapeutic method and diagnostic method 未知
公开(公告)号：AU2015218098A1
公开(公告)日：2016-09-15
申请号：AU2015218098
申请日：2015-02-10
申请人： BEIJING ADVACCINE BIOTECHNOLOGY CO LTD , HE ZHONGHUAI , JIN JIN , WANG BIN , XIE XIAOPING , YU QINGLING
发明人： WANG BIN , JIN JIN , XIE XIAOPING , HE ZHONGHUAI , YU QINGLING
IPC分类号： A61K38/20 , A61P31/16
摘要： Disclosed is an immunotherapeutic composition comprising IL-17. Also disclosed is a method of increasing the required immune response of subjects. The method can comprise applying the immunotherapeutic composition to subjects. The increased immune response can protect against flu virus. Further disclosed is a method of diagnosing flu virus infection.

7. 发明公开

EP1716863A4 T CELL IMMUNE RESPONSE INHIBITOR 审中-公开
标题翻译： T细胞免疫反应抑制剂
公开(公告)号：EP1716863A4
公开(公告)日：2010-08-18
申请号：EP05706576
申请日：2005-01-31
申请人： UNIV CHINA AGRICULTURAL
发明人： WANG BIN , YU QINGLING , JIN HUALI , KANG YOUMIN
IPC分类号： A61K38/16 , A61K39/00 , A61K48/00 , A61P37/02
CPC分类号： A61K39/00 , A61K48/00 , A61K2039/57

8. 发明公开

EP1963513A4 ALLERGY INHIBITOR COMPOSITIONS AND KITS AND METHODS OF USING THE SAME 有权
标题翻译：过敏炎性组合物和药盒和施用方法
公开(公告)号：EP1963513A4
公开(公告)日：2010-07-14
申请号：EP06848810
申请日：2006-12-22
申请人： UNIV CHINA AGRICULTURAL , WYETH LLC
发明人： WANG BIN , JIN HUALI , KANG YOUMIN , CHU HSIEN-JUE , NG KALEUNG
IPC分类号： A61K39/00 , A61K39/02 , A61K39/12 , A61K39/36 , A61K39/385 , A61K39/395
CPC分类号： A61K39/35 , A61K39/0003 , A61K39/0005 , A61K39/0008 , A61K2039/53 , A61K2039/57
摘要： Compositions and kits for inhibiting an allergic response against an allergenic protein are disclosed. The compositions comprise a eukaryotic cell expression vector containing nucleotide sequences encoding an allergenic protein or a polypeptide that comprises an antigenic epitope of said allergenic protein; and an allergenic protein or a polypeptide that comprises an antigenic epitope of the allergenic protein. The kits comprise a first container which comprises a eukaryotic cell expression vector containing nucleotide sequences encoding an allergenic protein or a polypeptide that comprises an antigenic epitope of the allergenic protein and a second container which comprises an allergenic protein or a polypeptide that comprises an antigenic epitope of said allergenic protein. Compositions and kits for inhibiting an allergic response against an flea allergenic protein; a feline allergenic protein; a canine allergenic protein; a dust mite allergenic protein; a peanut allergenic protein; a Japanese cedar allergenic protein; and a blomia tropicalis allergenic protein are disclosed. Methods if using such compositions and kits are also disclosed.

9. 发明公开

EP2140884A4 A VACCINE PREVENTING AND/OR TREATING AUTOIMMUNE DISEASES 有权
标题翻译：疫苗用于预防和/或治疗自身免疫疾病
公开(公告)号：EP2140884A4
公开(公告)日：2010-06-02
申请号：EP08714993
申请日：2008-03-19
申请人： UNIV CHINA AGRICULTURAL
发明人： WANG BIN , JIN HUALI , KANG YOUMIN , ZHANG WENJUAN , YU YANG , LI JINYAO
IPC分类号： A61K39/00 , A61K31/7088 , A61P3/10 , A61P37/00
CPC分类号： A61K39/0008 , A01K2267/0325 , A61K2039/53 , A61K2039/545
摘要： The present invention discloses a vaccine preventing and/or treating autoimmune diseases. Its active component is: the mixture consisting of a protein antigen causing an autoimmune disease or the epitope polypeptides thereof, and the recombinant eukaryotic vector with the coding genes of an autoantigen or the epitope polypeptides thereof inserted into multiple cloning sites. The autoantigen is insulin, glutamic acid decarboxylase or heat shock protein, myelin oligodendrocyte glycoprotein, two myelin antigens, zona pellucida 3, myoglobulin, type II collagen, thyroglobulin, cell membrane surface antigen, type II colloid antigen, acetylcholine receptor, thyrocyte cell surface antigen, salivary gland duct antigen, thyroglobulin, superantigen, or interphotoreceptor retinoid binding protein. The vaccine can inhibit the proliferation of T cells of immune animals and humans, induce the occurrence of immune suppression, as well as prevent and/or treat autoimmune diseases effectively.

10. 发明公开

EP3247745A4 FLUOROPOLYMER-BASED POLYMER BLENDS, POLYMER FILMS, AND POLARIZER PROTECTIVE FILMS 有权
公开(公告)号：EP3247745A4
公开(公告)日：2018-07-11
申请号：EP16740841
申请日：2016-01-22
申请人： AKRON POLYMER SYSTEMS INC , ZHENG XIAOLIANG , HARRIS FRANK W , KUO THAUMING , WANG BIN , GERMROTH TED CALVIN , ZHANG DONG , MCWILLIAMS DOUGLAS S
发明人： ZHENG XIAOLIANG , HARRIS FRANK W , KUO THAUMING , WANG BIN , GERMROTH TED , ZHANG DONG , MCWILLIAMS DOUGLAS S
IPC分类号： C08L27/12 , C08J5/18 , C08L33/08 , G02B5/30 , G02F1/1335
CPC分类号： G02B5/305 , C08F12/20 , C08K5/3415 , C08L25/18 , C08L33/08 , C08L33/12 , G02B1/04 , G02B1/14 , G02B5/3083 , C08L27/12 , C08L33/10
摘要： A polymer blend includes a combination of an acrylic polymer and a styrenic fluoropolymer. The polymer blend may be used to make polymer films having a single glass transition temperature, a polarizing plate, or a display device with enhanced optical properties.

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