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    • 1. 发明申请
    • METHOD AND DEVICE FOR MICROREACTOR PRESSURE CONTROL
    • 微型压力控制的方法和装置
    • WO2009082535A2
    • 2009-07-02
    • PCT/US2008080200
    • 2008-10-16
    • UNIV CALIFORNIAVAN DAM R MICHAELLIU KANSHEN KWANG-FU CLIFTONTSENG HSIAN-RONG
    • VAN DAM R MICHAELLIU KANSHEN KWANG-FU CLIFTONTSENG HSIAN-RONG
    • C12M1/02
    • B01J19/0093B01J2219/00783B01J2219/00907B01J2219/0097
    • A microfluidic device has a device body, wherein the device body defines a microfluidic reactor and a pressure control system therein, the pressure control system being arranged proximate the microfluidic reactor. The microfluidic device also has a fluid-permeable membrane arranged between the microfluidic reactor and the pressure control system, the fluid-permeable membrane having a surface area and thickness such that a fluid can pass from a high pressure side to a low pressure side of said fluid-permeable membrane during operation of the microfluidic device to at least one of change a pressure in the microfluidic reactor in a preselected manner, to maintain a substantially constant pressure in the microfluidic reactor, to change a composition of fluids in the microfluidic reactor, or maintain a composition of fluids in the microfluidic reactor. A method on performing chemical reactions includes introducing a plurality of chemical substances into a microfluidic reactor, wherein the microfluidic reactor has a fluid-permeable membrane between at least a portion of the microfluidic reactor and a microfluidic pressure control system; and at least one of pressurizing with a fluid or evacuating a region of the pressure control system proximate the fluid-permeable membrane to cause fluid to pass through the fluid-permeable membrane in a predetermined manner in order to cause a predetermined effect on a chemical reaction in the microfluidic reactor.
    • 微流体装置具有装置主体,其中装置主体在其中限定微流体反应器和压力控制系统,压力控制系统布置在微流体反应器附近。 微流体装置还具有布置在微流体反应器和压力控制系统之间的流体渗透膜,流体可渗透膜具有表面积和厚度,使得流体可以从所述流体可渗透膜的高压侧到低压侧 将微流体装置操作期间的流体可渗透膜以至少一种以预选的方式改变微流体反应器中的压力,以保持微流体反应器中基本上恒定的压力,以改变微流体反应器中的流体的组成,或 保持微流体反应器中的流体组成。 执行化学反应的方法包括将多种化学物质引入到微流体反应器中,其中所述微流体反应器在所述微流控反应器的至少一部分与微流控压力控制系统之间具有流体可渗透膜; 以及至少一个用流体加压或排出压力控制系统的靠近流体可渗透膜的区域,以使流体以预定的方式通过流体可渗透膜,以对化学反应产生预定的影响 在微流体反应器中。