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1. 发明申请

WO2005017487A2 MATRIX FOR MALDI ANALYSIS BASED ON POROUS POLYMER MONOLITHS 审中-公开
标题翻译：基于多孔聚合物单体的MALDI分析矩阵
公开(公告)号：WO2005017487A2
公开(公告)日：2005-02-24
申请号：PCT/US2004018499
申请日：2004-06-09
申请人： UNIV CALIFORNIA
发明人： FRECHET JEAN M J , SVEC FRANTISEK , PETERSON DOMINIC S , LUO QUANZHOU
IPC分类号： G01N20060101 , H01J49/00 , H01J49/16 , G01N
CPC分类号： H01J49/0418
摘要： The use of porous polymer monolithic matrix for matrix-assisted laser desorption/ionization time of flight mass spectrometry analysis on a sample suspected of containing an analyte is herein described. The porous polymer monoliths provide a matrix suitable for use in detecting and analyzing low molecular weight and small molecules. The matrices described herein also facilitate the creation of arrays of monolithic matrices for high-throughput detection and screening using MALDI-TOF mass spectrometry and exhibit a long shelf-life.
摘要翻译：本文描述了在疑似含有分析物的样品上使用多孔聚合物整体式基质用于基质辅助激光解吸/电离飞行时间质谱分析。多孔聚合物整料提供适用于检测和分析低分子量和小分子的基质。本文所述的基质还有助于创建用于高通量检测和筛选的单片矩阵阵列，其使用MALDI-TOF质谱法并展现出长的保存期限。

2. 发明申请

WO2008061222A9 METHOD AND SYSTEM FOR SEPARATING ANALYTES 审中-公开
标题翻译：用于分离分析的方法和系统
公开(公告)号：WO2008061222A9
公开(公告)日：2008-07-24
申请号：PCT/US2007084940
申请日：2007-11-16
申请人： UNIV INDIANA RES & TECH CORP , UNIV CALIFORNIA , NUROK DAVID , NOVOTNY ALLYSON L , STACHOWIAK TIMOTHY , SVEC FRANTISEK
发明人： NUROK DAVID , NOVOTNY ALLYSON L , STACHOWIAK TIMOTHY , SVEC FRANTISEK
IPC分类号： B01D15/08
CPC分类号： G01N30/92 , B01D15/38 , B01J20/261 , B01J20/285 , B01J2220/82 , G01N27/44747 , G01N2030/285 , G01N2030/906
摘要： A method and device for performing chromatography includes placing a monolithic polymer layer in contact with a liquid mobile phase. The monolithic polymer layer may be neutral, positively charged, or negatively charged. A first electrode and second electrode are coupled to the monolithic polymer layer. An electrical potential is created between the first electrode and the second electrode. In some embodiments, the monolithic polymer layer may be placed in a sealed chamber, which may have a pressure greater than atmospheric pressure. Additionally, in some embodiments, the mobile phase is advanced through the monolithic polymer layer via one of a number of forced flow techniques.
摘要翻译：用于进行色谱分析的方法和装置包括将单片聚合物层放置成与液体流动相接触。单块聚合物层可以是中性的，带正电的或带负电荷的。第一电极和第二电极连接到单片聚合物层。在第一电极和第二电极之间产生电势。在一些实施例中，单片聚合物层可以放置在密封室中，该密封室可以具有大于大气压的压力。另外，在一些实施方式中，流动相经由单片聚合物层经由多种强制流动技术之一被推进。

3. 发明申请

WO2009137267A2 SUPERHYDROPHOBIC AND SUPERHYDROPHILIC MATERIALS, SURFACES AND METHODS 审中-公开
标题翻译：超级和超级材料，表面和方法
公开(公告)号：WO2009137267A2
公开(公告)日：2009-11-12
申请号：PCT/US2009041277
申请日：2009-04-21
申请人： UNIV CALIFORNIA , SVEC FRANTISEK , LEVKIN PAVEL A , FRECHET JEAN M J
发明人： SVEC FRANTISEK , LEVKIN PAVEL A , FRECHET JEAN M J
IPC分类号： C08J9/224 , C08J5/00 , C08J9/22 , C08K7/00 , C08L25/08 , C08L33/06 , C08L33/14
CPC分类号： C08J9/286 , C08F220/18 , C08F222/1006 , C08J5/00 , C08J2333/16 , C08L33/16 , Y10T428/24355
摘要： A broadly applicable method requiring no more than a single step facilitates the preparation of large area super hydrophobic or super hydrophilic surfaces on a variety of substrates such as such as glass, metal, plastic, paper, wood, concrete and masonry. The technique involves the free radical polymerization of common acrylic or styrenic monomers in the presence of porogenic solvents in a mold or on a free surface. The material can be semi- or fully- transparent and either super hydrophobic or super hydrophilic depending on the choice of the monomers. Because porosity and dual scale roughness are intrinsic bulk properties of the monolithic materials and not only a surface characteristic, the polymers can be powdered to produce a super hydrophobic powder or otherwise fragmented and attached to the surface of any object to render it super hydrophobic or super hydrophilic. The surface properties of the porous material may also be altered locally by photografting with selected monomers.
摘要翻译：广泛应用的方法不需要单一步骤便于在各种基材如玻璃，金属，塑料，纸，木材，混凝土和砖石上制备大面积超疏水或超亲水表面。该技术涉及常规丙烯酸或苯乙烯类单体在造孔溶剂存在下在模具中或自由表面上的自由基聚合。根据单体的选择，该材料可以是半透明的或完全透明的，并且是超疏水的或超亲水的。由于孔隙率和双重尺度粗糙度是整体材料的固有本体特性，不仅表面特性，聚合物可以被粉末化以产生超疏水性粉末，或以其他方式分散和附着到任何物体的表面，使其超疏水或超级亲水性。多孔材料的表面性质也可以通过用选择的单体进行光刻而局部改变。

4. 发明申请

WO2008061222A3 METHOD AND SYSTEM FOR SEPARATING ANALYTES 审中-公开
标题翻译：分析分析方法和系统
公开(公告)号：WO2008061222A3
公开(公告)日：2008-09-12
申请号：PCT/US2007084940
申请日：2007-11-16
申请人： UNIV INDIANA RES & TECH CORP , UNIV CALIFORNIA , NUROK DAVID , NOVOTNY ALLYSON L , STACHOWIAK TIMOTHY , SVEC FRANTISEK
发明人： NUROK DAVID , NOVOTNY ALLYSON L , STACHOWIAK TIMOTHY , SVEC FRANTISEK
IPC分类号： B01D15/08
CPC分类号： G01N30/92 , B01D15/38 , B01J20/261 , B01J20/285 , B01J2220/82 , G01N27/44747 , G01N2030/285 , G01N2030/906
摘要： A method and device for performing chromatography includes placing a monolithic polymer layer in contact with a liquid mobile phase. The monolithic polymer layer may be neutral, positively charged, or negatively charged. A first electrode and second electrode are coupled to the monolithic polymer layer. An electrical potential is created between the first electrode and the second electrode. In some embodiments, the monolithic polymer layer may be placed in a sealed chamber, which may have a pressure greater than atmospheric pressure. Additionally, in some embodiments, the mobile phase is advanced through the monolithic polymer layer via one of a number of forced flow techniques.
摘要翻译：用于进行色谱法的方法和装置包括将整体聚合物层与液体流动相接触。整体聚合物层可以是中性的，带正电的或带负电的。第一电极和第二电极耦合到整体聚合物层。在第一电极和第二电极之间产生电位。在一些实施例中，整体聚合物层可以放置在可能具有大于大气压力的压力的密封室中。另外，在一些实施方案中，流动相通过多个强制流动技术之一进入整个单体聚合物层。

5. 发明专利

CA2669725A1 METHOD AND SYSTEM FOR SEPARATING ANALYTES 未知
公开(公告)号：CA2669725A1
公开(公告)日：2008-05-22
申请号：CA2669725
申请日：2007-11-16
申请人： UNIV CALIFORNIA , UNIV INDIANA RES & TECH CORP
发明人： NOVOTNY ALLYSON L , NUROK DAVID , STACHOWIAK TIMOTHY , SVEC FRANTISEK
IPC分类号： B01D15/10 , B01D15/26
摘要： A method and device for performing chromatography includes placing a mono lithic polymer layer in contact with a liquid mobile phase. The monolithic p olymer layer may be neutral, positively charged, or negatively charged. A fi rst electrode and second electrode are coupled to the monolithic polymer lay er. An electrical potential is created between the first electrode and the s econd electrode. In some embodiments, the monolithic polymer layer may be pl aced in a sealed chamber, which may have a pressure greater than atmospheric pressure. Additionally, in some embodiments, the mobile phase is advanced t hrough the monolithic polymer layer via one of a number of forced flow techn iques.

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