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1. 发明申请

WO2010020668A1 A COSMETIC COMPOSITION 审中-公开
标题翻译：化妆品组合物
公开(公告)号：WO2010020668A1
公开(公告)日：2010-02-25
申请号：PCT/EP2009/060754
申请日：2009-08-20
申请人： UNILEVER NV , UNILEVER PLC , HINDUSTAN UNILEVER LIMITED , GADGIL, Vijay, Ramchandra , GAURAV, Kumar , KUNJUPILLAI, Balu
发明人： GADGIL, Vijay, Ramchandra , GAURAV, Kumar , KUNJUPILLAI, Balu
IPC分类号： A61K8/35 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/368 , A61K8/40 , A61K8/416
摘要： The present application relates to a composition which includes water-soluble 1,3-diketone sunscreens, more particularly, water-soluble dibenzoylmethane sunscreens, where the sunscreens exhibit relatively low photodegradation; and a method for reducing the photodegradation of the water-soluble 1,3-diketone sunscreens. It is an object of the present application to provide a composition, which includes a water-soluble 1,3-diketone sunscreen, where the photodegradation of 1,3-diketone sunscreen is relatively low. The present inventors have found that water-soluble dibenzoylmethanes too suffer from the problem of photodegradation. It has been found that use of conventional stabilizers do not provide adequate stability. It has also been found that the stability of water-soluble 1,3-diketones is affected in the presence of conventional emulsifiers/surfactants, which are often included in cosmetic compositions.
摘要翻译：本申请涉及包含水溶性1,3-二酮防晒剂，更具体地说是水溶性二苯甲酰甲烷防晒剂的组合物，其中防晒剂显示相对低的光降解; 以及降低水溶性1,3-二酮防晒剂的光降解的方法。本申请的目的是提供一种组合物，其包含水溶性1,3-二酮防晒剂，其中1,3-二酮防晒剂的光降解相对较低。本发明人发现，水溶性二苯甲酰甲烷也遭受光降解的问题。已经发现使用常规的稳定剂不能提供足够的稳定性。还已经发现，在常规的乳化剂/表面活性剂的存在下，水溶性1,3-二酮的稳定性受到影响，这常常包括在化妆品组合物中。

2. 发明申请

WO2011045150A2 A PERSONAL CARE COMPOSITION 审中-公开
标题翻译：个人护理组合
公开(公告)号：WO2011045150A2
公开(公告)日：2011-04-21
申请号：PCT/EP2010/063891
申请日：2010-09-21
申请人： UNILEVER NV , UNILEVER PLC , HINDUSTAN UNILEVER LIMITED , SHUKLA, Ravi, Kant , GADGIL, Vijay, Ramchandra , BANDYOPADHYAY, Punam , HEGDE, Anil, Shankarnarayana
发明人： SHUKLA, Ravi, Kant , GADGIL, Vijay, Ramchandra , BANDYOPADHYAY, Punam , HEGDE, Anil, Shankarnarayana
CPC分类号： A61Q17/04 , A61K8/355 , A61K8/602 , A61K8/97 , A61Q15/00 , A61Q19/02
摘要： The present invention relates to a personal care composition for topical application comprising selective fractions of natural materials having photoprotective and skin lightening applications. The inventors found that certain fractions of natural materials which are rich in anthroquinones or naphthaquinones e.g. those from the Rubiaceae family provide for enhanced broad spectrum photoprotection especially in the visible range while also exhibiting enhanced activity in a biochemical pathway viz. tyrosinase inhibition which is indicative of improved skin lightening.
摘要翻译：本发明涉及一种用于局部应用的个人护理组合物，其包含具有光保护和皮肤增亮应用的天然材料的选择性部分。本发明人发现，富含蒽醌或萘醌的天然物质的某些馏分如来自茜草科的那些提供增强的广谱光保护，特别是在可见光范围内，同时也表现出增强的生物化学途径的活性。酪氨酸酶抑制指示改善皮肤亮度。

3. 发明申请

WO2011144536A1 A PERSONAL CARE COMPOSITION 审中-公开
标题翻译：个人护理组合
公开(公告)号：WO2011144536A1
公开(公告)日：2011-11-24
申请号：PCT/EP2011/057790
申请日：2011-05-13
申请人： UNILEVER NV , UNILEVER PLC , HINDUSTAN UNILEVER LIMITED , BANDYOPADHYAY, Punam , BANSAL, Vishi , GADGIL, Vijay, Ramchandra , SHARIFF, Rezwan , SHUKLA, Ravi, Kant
发明人： BANDYOPADHYAY, Punam , BANSAL, Vishi , GADGIL, Vijay, Ramchandra , SHARIFF, Rezwan , SHUKLA, Ravi, Kant
IPC分类号： A61K8/97 , A61Q19/02
CPC分类号： A61K8/97 , A61K8/498 , A61Q19/02
摘要： The present invention relates to a personal care composition for topical application having a skin lightening application. It is an object of the present invention to provide for a personal care composition that comprises fractions obtained from natural sources that gives enhanced skin lightening as compared to known fractions from natural sources.
摘要翻译：本发明涉及一种具有皮肤增亮应用的局部应用的个人护理组合物。本发明的目的是提供一种个人护理组合物，其包含与天然来源的已知级分相比提供增强的皮肤增亮的天然来源获得的级分。

4. 发明公开

EP2571483A1 A PERSONAL CARE COMPOSITION 有权
标题翻译：个人护理成分
公开(公告)号：EP2571483A1
公开(公告)日：2013-03-27
申请号：EP11721476.7
申请日：2011-05-13
申请人： Unilever NV , Unilever PLC
发明人： BANDYOPADHYAY, Punam , BANSAL, Vishi , GADGIL, Vijay, Ramchandra , SHARIFF, Rezwan , SHUKLA, Ravi, Kant
IPC分类号： A61K8/97 , A61Q19/02
CPC分类号： A61K8/97 , A61K8/498 , A61Q19/02
摘要： The present invention relates to a personal care composition for topical application having a skin lightening application. It is an object of the present invention to provide for a personal care composition that comprises fractions obtained from natural sources that gives enhanced skin lightening as compared to known fractions from natural sources.
摘要翻译：本发明涉及用于具有皮肤美白应用的局部应用的个人护理组合物。本发明的一个目的是提供一种个人护理组合物，其包含从天然来源获得的组分，与来自天然来源的已知组分相比，其提供增强的皮肤增亮。

5. 发明公开

EP2488153A2 A PERSONAL CARE COMPOSITION 审中-公开
标题翻译： KÖRPERPFLEGEZUSAMMENSETZUNG
公开(公告)号：EP2488153A2
公开(公告)日：2012-08-22
申请号：EP10754761.4
申请日：2010-09-21
申请人： Unilever NV , Unilever PLC
发明人： SHUKLA, Ravi, Kant , GADGIL, Vijay, Ramchandra , BANDYOPADHYAY, Punam , HEGDE, Anil, Shankarnarayana
IPC分类号： A61K8/35 , A61K8/60 , A61K8/97 , A61Q17/04 , A61Q19/02
CPC分类号： A61Q17/04 , A61K8/355 , A61K8/602 , A61K8/97 , A61Q15/00 , A61Q19/02
摘要： The present invention relates to a personal care composition for topical application comprising selective fractions of natural materials having photoprotective and skin lightening applications. The inventors found that certain fractions of natural materials which are rich in anthroquinones or naphthaquinones e.g. those from the Rubiaceae family provide for enhanced broad spectrum photoprotection especially in the visible range while also exhibiting enhanced activity in a biochemical pathway viz. tyrosinase inhibition which is indicative of improved skin lightening.
摘要翻译：本发明涉及一种用于局部应用的个人护理组合物，其包含具有光保护和皮肤增亮应用的天然材料的选择性部分。本发明人发现，富含蒽醌或萘醌的天然物质的某些馏分如来自茜科科的家族提供增强的广谱光保护，特别是在可见光范围内，同时也表现出增强的生物化学途径的活性。 ty-rosinase抑制，这表明改善皮肤亮度。

6. 发明申请

WO2018029080A1 HAIR TREATMENT COMPOSITION 审中-公开
标题翻译：头发护理组合物
公开(公告)号：WO2018029080A1
公开(公告)日：2018-02-15
申请号：PCT/EP2017/069676
申请日：2017-08-03
申请人： UNILEVER N.V. , UNILEVER PLC , CONOPCO, INC., D/B/A UNILEVER
发明人： DAS, Somnath , GADGIL, Vijay, Ramchandra , GHOSH, Debjani , JAGADISH, Nidhi
IPC分类号： A61Q7/00 , A61K8/19 , A61K8/20
摘要： The present invention relates to hair treatment compositions. In particular, the invention relates to hair treatment compositions that stimulate hair growth. Various compounds and combinations thereof have been reported for use in the treatment of hair to stimulate growth. Although the hair treatment compositions in the prior art provides for hair growth, there is unmet need for improved and superior compositions. It is therefore an object of the present invention to provide an improved and superior composition for stimulating hair growth. Disclosed is a hair treatment composition comprising (i) a polymorph of calcium carbonate; (ii) a water-soluble compound of calcium; and (iii) a suitable carrier. wherein said polymorph is at least one of calcite, vaterite or aragonite and wherein particle size of said polymorph is 1 µm to 10 µm.
摘要翻译：本发明涉及头发处理组合物。具体地说，本发明涉及刺激毛发生长的头发处理组合物。据报道，各种化合物及其组合已被用于治疗毛发以刺激生长。尽管现有技术中的头发处理组合物为毛发生长提供了条件，但仍未满足改进的和优异的组合物。因此，本发明的一个目的是提供用于刺激毛发生长的改进的和优异的组合物。公开了一种头发处理组合物，其包含（i）碳酸钙的多晶型物; （ii）钙的水溶性化合物; 和（iii）合适的载体。其中所述多晶型物是方解石，球霰石或文石中的至少一种，并且其中所述多晶型物的粒径为1微米至10微米。

7. 发明申请

WO2016071113A1 ANTI-AGEING COMPOSITION 审中-公开
标题翻译：抗老化组合物
公开(公告)号：WO2016071113A1
公开(公告)日：2016-05-12
申请号：PCT/EP2015/074406
申请日：2015-10-21
申请人： UNILEVER PLC , UNILEVER N.V. , CONOPCO, INC., D/B/A UNILEVER
发明人： BANSAL, Vishi , CASEY, John , GADGIL, Vijay, Ramchandra , WAINWRIGHT, Linda, Jane
IPC分类号： A61K8/31 , A61K8/34 , A61Q5/00 , A61Q7/00 , A61K8/97
CPC分类号： A61Q7/00 , A61K8/31 , A61K8/345 , A61K8/97 , A61Q5/00
摘要： The invention relates to an anti-ageing composition, in particular to a composition for treating hair ageing. Thus in one aspect of the invention, an oral or topical anti-ageing composition is provided, the oral or topical anti-ageing composition comprising a combination of a carotenoid and an aqueous or hydroalcoholic extract of the leaf and whole herb of Andrographis paniculata, wherein the oral or topical anti-ageing composition comprises more than 0.4% w/w andrographolide, and wherein the oral or topical anti-ageing composition excludes 18% dry weight Gymnema sylvastre leaf or 3% dry weight Andropogan muricatus root or 10% dry weight Achytantus aspera stem and leaf or 5% dry weight Withania somnifera root. The carotenoid is preferably lycopene or lutein. Features of hair ageing include hair loss, thinning hair, loss of shine and increased number of grey hairs.
摘要翻译：本发明涉及一种抗衰老组合物，特别涉及一种治疗头发老化的组合物。因此，在本发明的一个方面，提供口服或局部抗衰老组合物，所述口服或局部抗衰老组合物包含类胡萝卜素和泛酸穿心莲的全部药草的水合或水醇提取物的组合，其中口服或局部抗衰老组合物包含大于0.4％w / w穿心莲内酯，并且其中口服或局部抗衰老组合物不包括18％干重的Gymnema sylvastre叶或3％干重的安非他酮或10％干重Achytantus 茎叶和叶片或干重5％的干燥根茎。类胡萝卜素优选为番茄红素或叶黄素。头发老化的特征包括脱发，头发稀疏，光泽丧失和灰发数量增加。

8. 发明申请

WO2018095699A1 COSMETIC COMPOSITION COMPRISING NATURAL ACTIVES 审中-公开
公开(公告)号：WO2018095699A1
公开(公告)日：2018-05-31
申请号：PCT/EP2017/077737
申请日：2017-10-30
申请人： UNILEVER N.V. , UNILEVER PLC , CONOPCO, INC., D/B/A UNILEVER
发明人： GADGIL, Vijay, Ramchandra , KALATHIL, Ramitha , PERUMAL, Rajkumar , SHUKLA, Ravi, Kant , VAIDYA, Ashish, Anant
IPC分类号： A61K8/49 , A61Q17/00
摘要： Disclosed is a cosmetic composition comprising: (i) 0.1 to 10 % by weight pongamol; (ii) 0.1 to 10 % by weight karanjin; and, (iii) 0.1 to 40 % by weight of a solvent whose Total Hildebrand Parameter (5t) value is 18 to 26 MPa 0.5 at 25°C, wherein said composition comprises not more than 2 % by weight pongamia oil. The composition provides abrasion resistant photoprotection to skin.

9. 发明申请

WO2015101468A1 A NOVEL SUNSCREEN MOLECULE AND COMPOSITIONS THEREOF 审中-公开
标题翻译：一种新型SUNSCREEN分子及其组合物
公开(公告)号：WO2015101468A1
公开(公告)日：2015-07-09
申请号：PCT/EP2014/077324
申请日：2014-12-11
申请人： UNILEVER N.V. , UNILEVER PLC , CONOPCO, INC., D/B/A UNILEVER
发明人： CHAVAN, Mohan, Vijaykumar , GADGIL, Vijay, Ramchandra , KUNJUPILLAI, Balu , VAIDYA, Ashish, Anant
IPC分类号： C07J9/00 , C07J41/00 , A61K8/63
CPC分类号： A61K8/63 , A61K2800/57 , A61Q17/04 , C07J9/005 , C07J41/0094
摘要： The present invention relates to a broad spectrum stable sunscreen molecule having the general structure (Formula) where "X" is an organic sunscreen belonging to the UVA class and "Y" is an organic sunscreen belonging to UVB class or vice-versa. The invention also relates to a stable sunscreen composition comprising the inventive sunscreen molecule, a UV-B organic sunscreen and a cosmetically acceptable base. The invention also relates to a method of providing UV protection to the sun-exposed parts of human or animal body comprising the step of applying the above composition.
摘要翻译：本发明涉及具有一般结构（式）的广谱稳定防晒分子，其中“X”是属于UVA类的有机防晒霜，“Y”是属于UVB类的有机防晒剂，反之亦然。本发明还涉及一种稳定的防晒组合物，其包含本发明的防晒剂分子，UV-B有机防晒剂和美容上可接受的碱。本发明还涉及向人体或动物体的阳光暴露部分提供紫外线防护的方法，其包括应用上述组合物的步骤。

10. 发明申请

WO2016045902A1 ANTI-AGEING COMPOSITION COMPRISING RESVERATROL AND ANDROGRAPHOLIDE 审中-公开
标题翻译：包含RESVERATROL和ANDROGRAPHOLIDE的抗老化组合物
公开(公告)号：WO2016045902A1
公开(公告)日：2016-03-31
申请号：PCT/EP2015/069551
申请日：2015-08-26
申请人： UNILEVER PLC , UNILEVER N.V. , CONOPCO, INC., D/B/A UNILEVER
发明人： BANSAL, Vishi , CASEY, John , GADGIL, Vijay, Ramchandra , WAINWRIGHT, Linda, Jane
IPC分类号： A61K9/00 , A61K36/889 , A61Q19/08 , A61K31/05 , A61P17/18
CPC分类号： A61K9/0053 , A61K8/0216 , A61K8/347 , A61K8/97 , A61K9/08 , A61K31/05 , A61K36/19 , A61K2800/92 , A61Q19/08 , A61K2300/00
摘要： The invention relates to an oral anti-ageing composition, in particular to an oral anti-ageing composition comprising resveratrol and an aqueous or hydroalcoholic extract of the leaf and whole herb of Andrographis paniculata. The inventors have observed a synergistic up-regulation of haemoxygenase-1 (HO-1) in primary human dermal fibroblast cells treated with a combination of aqueous extract of the whole herb of Andrographis paniculata and resveratrol. Thus in a first aspect of the invention, an oral anti-ageing composition is provided, the oral anti-ageing composition comprising resveratrol and an aqueous or hydroalcoholic extract of the leaf and whole herb of Andrographis paniculata, wherein the oral or topical anti-ageing composition comprises more than 0.4 % w/w andrographolide, wherein the oral anti-ageing composition comprises a daily dosage of 10 to 500, preferably 50 to 300 mg resveratrol in the form of one or more unit doses. Other aspects of the invention are also described.
摘要翻译：本发明涉及一种口服抗衰老组合物，特别是涉及一种口服抗衰老组合物，其包含白藜芦醇和穿心莲的叶和全草药的水溶液或水醇提取物。发明人已经观察到，使用穿心莲和白藜芦醇的全草药水提物处理的原代人真皮成纤维细胞中，加氧酶-1（HO-1）的协同上调。因此，在本发明的第一方面中，提供了一种口服抗衰老组合物，所述口服抗衰老组合物包含白藜芦醇和黄连衣原体的叶和全药草的水溶液或水醇提取物，其中口服或局部抗衰老组合物包含大于0.4％w / w穿心莲内酯，其中口服抗衰老组合物包含10至500，优选50至300mg白藜芦醇的日剂量，其为一种或多种单位剂量的形式。还描述了本发明的其它方面。

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