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1. 发明申请

WO2010095911A2 COMPOSITION FOR ENHANCING IMMUNITY CONTAINING PLANT STEM CELL LINE DERIVED FROM CAMBIUM OF PANAX GINSENG INCLUDING WILD GINSENG OR GINSENG AS AN ACTIVE INGREDIENT 审中-公开
标题翻译：用于增强含人参的人参茎干细胞系（含野生人参或人参为活性成分）的免疫力的组合物
公开(公告)号：WO2010095911A2
公开(公告)日：2010-08-26
申请号：PCT/KR2010001116
申请日：2010-02-23
申请人： UNHWA CORP , LEE DAE HEE , JANG MI OK , LIM MIN JUNG , HONG SUN MI , JIN YOUNG WOO , LEE EUN KYONG
发明人： LEE DAE HEE , JANG MI OK , LIM MIN JUNG , HONG SUN MI , JIN YOUNG WOO , LEE EUN KYONG
IPC分类号： A61K36/258 , A61P37/00
CPC分类号： A61K36/258 , A01H4/005 , A23L33/105 , A23V2002/00 , C12N5/04 , A23V2200/324 , A23V2250/2124
摘要： The present invention relates to a composition for enhancing immunity containing a cell line derived from the cambium of Panax ginseng including wild ginseng or ginseng, or the grounded substance, extract, or culture medium of the cell line as an active ingredient. The cell line and ground substance, extract, and culture medium of the cell line according to the present invention compose a natural product-derived composition. The cell line, ground substance, extract, and culture medium are safe to a human body by minimizing side effects of a conventional immunity booster, and also effectively increase activity of NK cells charging innate immunity. As well, the cell line, ground substance, extract, and culture medium appear to enhance acquired immunity by increasing proliferation rate of lymph node cells when re-exposing the cells to an antigen in a specific immune reaction, thus are useful as an immunity booster. Especially, the cell line, ground substance, extract, and culture medium also effectively increase the number of bone marrow cells, thus are not only used as an immune reaction adjuvant, but also used in preventing and treating anemia caused by hematopoiesis.
摘要翻译：本发明涉及用于增强免疫力的组合物，其含有来自人参形成层的细胞系，包括野山参或人参，或者细胞系的研磨物质，提取物或培养基作为活性成分。根据本发明的细胞系的细胞系和基础物质，提取物和培养基构成天然产物衍生的组合物。通过使常规免疫增强剂的副作用最小化，细胞系，基础物质，提取物和培养基对人体是安全的，并且还有效地增加NK细胞充电先天免疫的活性。同样，细胞系，基础物质，提取物和培养基通过在特定的免疫反应中将细胞再次暴露于抗原时增加淋巴结细胞的增殖速率而增强获得性免疫，因此可用作免疫增强剂。特别是细胞系，粉碎物，提取物和培养基也有效地增加了骨髓细胞的数量，因此不仅可以用作免疫反应佐剂，而且还可以用于预防和治疗造血系统引起的贫血症。

2. 发明申请

WO2010019016A3 COMPOSITION FOR PREVENTING OR TREATING LIVER DISEASES, CONTAINING PLANT STEM CELL LINES DERIVED FROM THE CAMBIUM OF PANAX GINSENG INCLUDING MOUNTAIN GINSENG OR GINSENG AS ACTIVE INGREDIENT 审中-公开
标题翻译：用于预防或治疗肝病的组合物，含有源自人参的人参茎干细胞系，包括人参山参或人参作为活性成分
公开(公告)号：WO2010019016A3
公开(公告)日：2010-06-17
申请号：PCT/KR2009004563
申请日：2009-08-14
申请人： UNHWA BIOTECH CORP , JIN YOUNG WOO , LEE EUN KYONG , LIM MIN JUNG , KIM YOUNG MEE , HONG SUN MI , JANG MI OK , GU IN SOOK , CHOI KUM E
发明人： JIN YOUNG WOO , LEE EUN KYONG , LIM MIN JUNG , KIM YOUNG MEE , HONG SUN MI , JANG MI OK , GU IN SOOK , CHOI KUM E
IPC分类号： A61K36/258 , A23L1/30 , A61K35/00 , C12N5/04
CPC分类号： A61K36/258 , A01H4/005 , A23L33/105 , A61K36/25 , C12N5/04
摘要： The present invention relates to a composition for the prevention or treatment of liver diseases, containing, as active ingredients, one or more of the following: homogeneous cell lines derived from the cambium of Panax ginseng including mountain ginseng or regular ginseng, a fraction thereof, an extraction thereof, and a culture thereof. The homogeneous cell lines derived from the cambium of Panax ginseng including mountain or regular ginseng, a fraction thereof, an extraction thereof, and a culture thereof, minimize the negative side effects of existing therapeutic agents for liver diseases, and are safe for the human body. Further, the present invention is useful in preventing and treating liver diseases as it increases the s-antibody (HBsAb) and the e-antibody (HBeAb) to the hepatitis virus and inhibits the growth of the hepatitis virus. Further, the present invention is useful as functional foods for improving the hepatic function as it lowers the liver damage index.
摘要翻译：本发明涉及用于预防或治疗肝脏疾病的组合物，其含有以下一种或多种作为活性成分：衍生自人参形成层的同质细胞系，包括山参或普通人参，其部分，其提取物及其培养物。来源于人参形成层（包括高山或正常人参）的成分细胞系，其部分，其提取物及其培养物使现有治疗剂对肝病的负面影响最小化，并且对人体是安全的。另外，本发明对于肝病的预防和治疗是有用的，因为它可以增加肝炎病毒的s-抗体（HBsAb）和e抗体（HBeAb）并抑制肝炎病毒的生长。另外，本发明作为降低肝损伤指数的肝功能改善用功能性食品是有用的。

3. 发明申请

WO2010053314A2 COMPOSITION FOR CANCER PREVENTION OR TREATMENT CONTAINING AS ACTIVE INGREDIENT PLANT STEM CELL LINE DERIVED FROM CAMBIUM OF PANAX GINSENG INCLUDING WILD GINSENG OR GINSENG 审中-公开
标题翻译：含有野生人参或人参的人参皂甙衍生的含有活性成分植物干细胞系的癌症预防或治疗组合物
公开(公告)号：WO2010053314A2
公开(公告)日：2010-05-14
申请号：PCT/KR2009006523
申请日：2009-11-06
申请人： UNHWA BIOTECH CORP , JIN YOUNG WOO , LEE EUN KYONG , LIM MIN JUNG , JANG MI OK , HONG SUN MI
发明人： JIN YOUNG WOO , LEE EUN KYONG , LIM MIN JUNG , JANG MI OK , HONG SUN MI
IPC分类号： A61K36/258
CPC分类号： A61K36/258 , A01H4/005 , A23L33/105 , A23V2002/00 , C12N5/04 , A23V2200/308 , A23V2250/21
摘要： The present invention relates to a composition for cancer prevention or treatment that contains, as an active ingredient, a cell line derived from the cambium of Panax ginseng including wild ginseng or ginseng, or the grounded substance, extract or culture medium of the cell line. The cell line, and the grounded substance, extract, and culture medium of the cell line, which are natural product-derived compositions, minimize the adverse reactions of the existing therapeutic agents, and directly intervene in the growth of a cancer, effectively and safely, thereby destroying and killing cancer cells in the human body, and exhibiting the anti-cancer activities of suppressing or alleviating tumor formation and growth, which is useful for cancer prevention and treatment and alleviation of cancer symptoms.
摘要翻译：本发明涉及一种用于癌症预防或治疗的组合物，其含有源自人参的形成层（包括野山参或人参）的细胞系或该细胞系的研磨物质，提取物或培养基作为活性成分。细胞系以及作为天然产物衍生组合物的细胞系的研磨物质，提取物和培养基使现有治疗剂的不良反应最小化，并且有效且安全地直接干预癌症的生长从而破坏和杀死人体内的癌细胞，并显示抑制或缓解肿瘤形成和生长的抗癌活性，这对于癌症预防和治疗以及减轻癌症症状是有用的。

4. 发明申请

WO2010038991A3 COMPOSITION FOR PREVENTING OR TREATING AIDS CONTAINING PLANT STEM CELL LINE DERIVED FROM CAMBIUM OF PANAX GINSENG INCLUDING WILD GINSENG OR GINSENG AS ACTIVE INGREDIENT 审中-公开
标题翻译：用于预防或治疗含有PANAX GINSENG CAMBIUM的植物干细胞系的艾滋病组合物，包括金山或金山作为活性成分
公开(公告)号：WO2010038991A3
公开(公告)日：2010-06-24
申请号：PCT/KR2009005618
申请日：2009-09-30
申请人： UNHWA BIOTECH CORP , JANG MI OK , HONG SUN MI , LEE EUN KYONG , JIN YOUNG WOO
发明人： JANG MI OK , HONG SUN MI , LEE EUN KYONG , JIN YOUNG WOO
IPC分类号： A61K36/258
CPC分类号： A61K36/258 , A01H4/005 , A23L33/10 , A23L33/105 , A23V2002/00 , C12N5/04 , A23V2200/30 , A23V2250/2124
摘要： The present invention relates to a composition for preventing or treating AIDS (Acquired immunodeficiency syndrome) containing one or more among a homogenous cell line derived from a cambium of Panax ginseng including wild ginseng or ginseng, and ground raw material, extract and culture of the homogenous cell line as active ingredients. The homogenous cell line and its ground raw material, extract and culture according to the present invention are natural product-derived compositions. They minimize side effects of existing therapeutic drugs and are safe for the human body. In addition, they effectively increase the number of T-cells such as CD4+ T-cells and reduce the number of HIVs (human immunodeficiency viruses). Thus, they prevent opportunistic infection, dysneuria, and neoplasia caused by immune incompetence, and ultimately the risk of death. Therefore, they are useful for preventing and treating AIDS and relieving symptoms of AIDS.
摘要翻译：本发明涉及一种预防或治疗含有野山参或人参中人参人参人造参的均质细胞系中含有一种或多种艾滋病（获得性免疫缺陷综合征）的组合物，研磨原料，提取物和均匀培养物细胞系作为活性成分。根据本发明的均质细胞系及其研磨原料，提取物和培养物是天然产物衍生的组合物。它们可以减少现有治疗药物的副作用，并且对人体是安全的。此外，它们有效地增加了CD4 + T细胞等T细胞的数量，并减少了HIV（人类免疫缺陷病毒）的数量。因此，它们阻止机会性感染，排尿障碍和由免疫功能不全引起的瘤形成，并最终导致死亡风险。因此，它们有助于预防和治疗艾滋病，缓解艾滋病的症状。

5. 发明申请

WO2010137879A2 PLANT STEM CELL DERIVED FROM CAMBIUM OF FAMILY SALICACEAE AND METHOD FOR ISOLATING AND CULTURING SAME 审中-公开
标题翻译：来自家蚕豆沙门氏菌的植物干细胞及其分离和培养方法
公开(公告)号：WO2010137879A2
公开(公告)日：2010-12-02
申请号：PCT/KR2010003342
申请日：2010-05-26
申请人： UNHWA CORP , HONG NAM JU , JIN YOUNG WOO , LEE EUN KYONG , HONG SUN MI
发明人： HONG NAM JU , JIN YOUNG WOO , LEE EUN KYONG , HONG SUN MI
IPC分类号： C12N5/04 , C12N5/02
CPC分类号： A01H5/04 , A01H4/005
摘要： The present invention relates to a stem cell derived from the cambium of family Salicaceae and to a method for isolating and culturing the same. The stem cell derived from the cambium of family Salicaceae according to the present invention is advantageous as it is isolated in an undifferentiated state without undergoing a dedifferentiation process and stably maintained without causing a variation in the cellular growth rate and growth pattern even during long-term culture, thereby enabling large-scale culture. In addition, the stem cell derived from the cambium of family Salicaceae according to the present invention exhibits the effects of suppressing the generation of NO during the treatment of Lipopolysaccharide (LPS) and suppressing the expression of the genes of COX-2 proinflammatory cytokine, and thus can be valuably used as an excellent anti-inflammatory composition.
摘要翻译：本发明涉及源自柳叶科植物的形成层的干细胞及其分离培养方法。根据本发明的衍生自柳科科的形成层的干细胞是有利的，因为它以未分化状态分离而不进行去分化过程并且即使在长期期间也不引起细胞生长速率和生长模式的变化而稳定地保持文化，从而实现大规模文化。此外，根据本发明的源自柳叶of科的形成层的干细胞表现出抑制脂多糖（LPS）处理期间产生NO并抑制COX-2促炎细胞因子基因表达的效果，因此可以有价值地用作优异的抗炎组合物。

6. 发明申请

WO2010137918A3 PLANT STEM CELL DERIVED FROM CAMBIUM OF FAMILY SOLANACEAE, AND METHOD FOR ISOLATING AND CULTURING SAME 审中-公开
标题翻译：来自家族林分系的植物干细胞及其分离和培养方法
公开(公告)号：WO2010137918A3
公开(公告)日：2011-04-14
申请号：PCT/KR2010003424
申请日：2010-05-28
申请人： UNHWA CORP , YU YOUNG MI , KIM SO YEON , JIN YOUNG WOO , LEE EUN KYONG , HONG SUN MI
发明人： YU YOUNG MI , KIM SO YEON , JIN YOUNG WOO , LEE EUN KYONG , HONG SUN MI
IPC分类号： C12N5/04 , C12N5/02
CPC分类号： A01H4/005 , C12N5/04
摘要： The present invention relates to a plant stem cell derived from the cambium of family Solanaceae, and to a method for isolating and culturing the same. A stem cell derived from the cambium of family Solanaceae, according to the present invention, is useful as it can be isolated in an undifferentiated state without undergoing a dedifferentiation process and stably maintained without causing any variation in the cell growth rate and growth pattern even during long-term culture, thereby enabling large-scale culture. Moreover, the stem cell derived from the cambium of family Solanaceae and the culture thereof, according to the present invention, are useful for preventing and delaying aging as they have the effects of inducing biosynthesis of procollagen and more efficiently inhibiting the generation of enzymes related to aging than retinoic acid, which is known as having an excellent effect in skin wrinkle improvement.
摘要翻译：本发明涉及源自茄科的形成层的植物干细胞及其分离培养方法。根据本发明，衍生自茄科的形成层的干细胞是有用的，因为它可以以未分化状态分离而不进行去分化过程并且在不引起细胞生长速率和生长模式的任何变化的情况下即使在长期文化，从而实现大规模文化。此外，根据本发明，衍生自茄科科植物的形成层的干细胞及其培养物可用于预防和延缓衰老，因为它们具有诱导前胶原的生物合成的效果，并且更有效地抑制与老化比视黄酸，其被认为具有优异的皮肤皱纹改善效果。

7. 发明申请

WO2010137877A3 PLANT STEM CELL DERIVED FROM CAMBIUM OF FAMILY ASTERACEAE AND METHOD FOR THE ISOLATED CULTURING THEREOF 审中-公开
标题翻译：来自家蚕亚种的植物干细胞及其分离培养的方法
公开(公告)号：WO2010137877A3
公开(公告)日：2011-04-14
申请号：PCT/KR2010003340
申请日：2010-05-26
申请人： UNHWA CORP , KIM IL SUK , PAEK JIN SOO , JIN YOUNG WOO , LEE EUN KYONG , HONG SUN MI
发明人： KIM IL SUK , PAEK JIN SOO , JIN YOUNG WOO , LEE EUN KYONG , HONG SUN MI
IPC分类号： C12N5/04 , C12N5/02
CPC分类号： C12N5/04 , A61K35/12
摘要： The present invention relates to a stem cell derived from cambium of family Asteraceae and to a method for the isolated culturing thereof. The stem cell derived from cambium of family Asteraceae according to the present invention is advantageous as it is isolated at a non-differentiated state without passing through a dedifferentiation process and stably maintained without causing a variation in the cellular growth rate and growth pattern even during a long-term culture, thereby enabling a mass culture. In addition, the stem cell derived from cambium of family Asteraceae according to the present invention and the culture thereof exhibit the effects of suppressing the generation of NO during the treatment of Lipopolysaccharide (LPS) and of suppressing the expression of the genes of COX-2 proinflammatory cytokine, and thus can be valuably used as an excellent anti-inflammatory composition.
摘要翻译：本发明涉及源自菊科的形成层的干细胞及其分离培养的方法。根据本发明的源自菊科的形成层的干细胞是有利的，因为它在非分化状态下分离而不通过去分化过程并稳定地保持，而不会引起细胞生长速率和生长模式的变化，即使在长期文化，从而实现群众文化。此外，根据本发明的源自菊科的形态层的干细胞及其培养物显示出在脂多糖（LPS）处理期间抑制NO产生并抑制COX-2基因表达的效果促炎细胞因子，因此可以有价值地用作优异的抗炎组合物。

8. 发明申请

WO2010137878A9 PLANT STEM CELL DERIVED FROM CAMBIUM OF FAMILY GINGKOACEAE AND METHOD FOR THE ISOLATION THEREOF 审中-公开
标题翻译：家蝇科植物CAM植物干细胞及其分离方法
公开(公告)号：WO2010137878A9
公开(公告)日：2011-02-03
申请号：PCT/KR2010003341
申请日：2010-05-26
申请人： UNHWA CORP , HONG NAM JU , JIN YOUNG WOO , LEE EUN KYONG , HONG SUN MI
发明人： HONG NAM JU , JIN YOUNG WOO , LEE EUN KYONG , HONG SUN MI
IPC分类号： C12N5/04 , C12N5/02
CPC分类号： A01H4/005 , A01H7/00
摘要： The present invention relates to a stem cell derived from cambium of family Gingkoaceae and to method for the isolated culturing thereof. The stem cell derived from cambium of family Gingkoaceae according to the present invention is advantageous as it is isolated at a non-differentiated state without passing through a dedifferentiation process and stably maintained without causing a variation in the cellular growth rate and growth pattern even during a long-term culture, thereby enabling a mass culture. In addition, the stem cell derived from cambium of family Gingkoaceae according to the present invention showed an antioxidant effect similar to or higher than that of existing synthetic antioxidants when the radical-scavenging activity for scavenging radicals generated by the treatment of an oxidant is measured, and thus can be valuably used as an excellent anti-inflammatory composition.
摘要翻译：本发明涉及来源于银杏科的形成层的干细胞及其分离培养方法。根据本发明的来自银杏科的形成层的干细胞是有利的，因为它在非分化状态下分离而不经过去分化过程，并且即使在细胞生长速率和生长模式期间也不会引起细胞生长速率和生长模式的变化而稳定地保持长期文化，从而实现大众文化。此外，根据本发明的来自银杏科的形成层的干细胞当测量由氧化剂处理产生的清除自由基的自由基清除活性时，显示出与现有合成抗氧化剂相似或更高的抗氧化效果，因此可以有价值地用作优异的抗炎组合物。

9. 发明申请

WO2010137878A3 PLANT STEM CELL DERIVED FROM CAMBIUM OF FAMILY GINGKOACEAE AND METHOD FOR THE ISOLATION THEREOF 审中-公开
标题翻译：来自家族金银花的植物干细胞及其分离方法
公开(公告)号：WO2010137878A3
公开(公告)日：2011-04-14
申请号：PCT/KR2010003341
申请日：2010-05-26
申请人： UNHWA CORP , HONG NAM JU , JIN YOUNG WOO , LEE EUN KYONG , HONG SUN MI
发明人： HONG NAM JU , JIN YOUNG WOO , LEE EUN KYONG , HONG SUN MI
IPC分类号： C12N5/04 , C12N5/02
CPC分类号： A01H4/005 , A01H7/00
摘要： The present invention relates to a stem cell derived from cambium of family Gingkoaceae and to method for the isolated culturing thereof. The stem cell derived from cambium of family Gingkoaceae according to the present invention is advantageous as it is isolated at a non-differentiated state without passing through a dedifferentiation process and stably maintained without causing a variation in the cellular growth rate and growth pattern even during a long-term culture, thereby enabling a mass culture. In addition, the stem cell derived from cambium of family Gingkoaceae according to the present invention showed an antioxidant effect similar to or higher than that of existing synthetic antioxidants when the radical-scavenging activity for scavenging radicals generated by the treatment of an oxidant is measured, and thus can be valuably used as an excellent anti-inflammatory composition.
摘要翻译：本发明涉及源自银杏科植物的形成层的干细胞及其分离培养方法。根据本发明的源自金丝桃科的形成层的干细胞是有利的，因为它以非分化状态分离而不通过去分化过程并稳定地保持，而不会引起细胞生长速率和生长模式的变化，即使在长期文化，从而实现群众文化。此外，根据本发明的衍生自银杏科科植物科的形成层的干细胞，当测量通过处理氧化剂产生的清除自由基的自由基清除活性时，显示出与现有的合成抗氧化剂相似或更高的抗氧化作用，因此可以有价值地用作优异的抗炎组合物。

10. 发明申请

WO2009038416A2 PLANT STEM CELL LINE DERIVED FROM QUIESCENT CENTER AND METHOD FOR ISOLATING THE SAME 审中-公开
标题翻译：从QUIESCENT中心衍生的植物干细胞系及其分离方法
公开(公告)号：WO2009038416A2
公开(公告)日：2009-03-26
申请号：PCT/KR2008005604
申请日：2008-09-22
申请人： UNHWA BIOTECH CORP , YU YOUNG-MI , LEE EUN KYONG , HONG SUN MI , JIN YOUNG WOO
发明人： YU YOUNG-MI , LEE EUN KYONG , HONG SUN MI , JIN YOUNG WOO
IPC分类号： C12N5/04
CPC分类号： C12N5/04
摘要： The present invention relates to a cell line derived from the quiescent center of a plant and a method for isolating the same, more specifically, relates to a quiescent center-derived homogeneous cell line of single-cell origin, which is obtained from the quiescent center of a plant without needing a separate de-differentiation process, and a method for isolating the same.
摘要翻译：本发明涉及从植物的静止中心衍生的细胞系及其分离方法，更具体地涉及从静止中心获得的单细胞来源的静态中心衍生的均质细胞系的植物，而不需要单独的去分化过程，以及用于分离其的方法。

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