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1. 发明申请

US20060258954A1 Biopsy forceps assemblies 有权
标题翻译：活检钳组件
公开(公告)号：US20060258954A1
公开(公告)日：2006-11-16
申请号：US11128319
申请日：2005-05-13
申请人： Tyler Timberlake , Changqing Li , Otto Anderhub , Douglas Bontrager , Gerardo Martin , Robert DeVries
发明人： Tyler Timberlake , Changqing Li , Otto Anderhub , Douglas Bontrager , Gerardo Martin , Robert DeVries
IPC分类号： A61B10/00 , A61B17/00
CPC分类号： A61B10/00 , A61B10/06 , A61B2017/00353 , A61B2017/2939 , A61B2017/320064
摘要： Embodiments of the invention include devices for obtaining tissue including a proximal actuator and a distal assembly having first and second end effectors. The first and second end effectors include the features of at least one element within the inner surface either of the first and second end effectors for aiding in the capture and retention of a targeted tissue sample.
摘要翻译：本发明的实施例包括用于获得组织的装置，包括近侧致动器和具有第一和第二端部执行器的远端组件。第一和第二末端执行器包括第一和第二末端执行器内的内表面中的至少一个元件的特征，用于帮助捕获和保持靶组织样本。

2. 发明授权

US07762960B2 Biopsy forceps assemblies 有权
标题翻译：活检钳组件
公开(公告)号：US07762960B2
公开(公告)日：2010-07-27
申请号：US11128319
申请日：2005-05-13
申请人： Tyler Timberlake , Changqing Li , Otto Anderhub , Douglas M. Bontrager , Gerardo Martin , Robert B. DeVries
发明人： Tyler Timberlake , Changqing Li , Otto Anderhub , Douglas M. Bontrager , Gerardo Martin , Robert B. DeVries
IPC分类号： A61B10/00 , A61B17/00
CPC分类号： A61B10/00 , A61B10/06 , A61B2017/00353 , A61B2017/2939 , A61B2017/320064
摘要： Embodiments of the invention include devices for obtaining tissue including a proximal actuator and a distal assembly having first and second end effectors. The first and second end effectors include the features of at least one element within the inner surface either of the first and second end effectors for aiding in the capture and retention of a targeted tissue sample.
摘要翻译：本发明的实施例包括用于获得组织的装置，包括近侧致动器和具有第一和第二端部执行器的远端组件。第一和第二末端执行器包括第一和第二末端执行器内的内表面中的至少一个元件的特征，用于帮助捕获和保持靶组织样本。

3. 发明授权

US08317726B2 Biopsy forceps assemblies 有权
标题翻译：活检钳组件
公开(公告)号：US08317726B2
公开(公告)日：2012-11-27
申请号：US12816248
申请日：2010-06-15
申请人： Tyler Timberlake , Changqing Li , Otto Anderhub , Douglas M. Bontrager , Gerardo Martin , Robert B. DeVries
发明人： Tyler Timberlake , Changqing Li , Otto Anderhub , Douglas M. Bontrager , Gerardo Martin , Robert B. DeVries
IPC分类号： A61B17/28
CPC分类号： A61B10/00 , A61B10/06 , A61B2017/00353 , A61B2017/2939 , A61B2017/320064
摘要： Embodiments of the invention include devices for obtaining tissue including a proximal actuator and a distal assembly having first and second end effectors. The first and second end effectors include the features of at least one element within the inner surface either of the first and second end effectors for aiding in the capture and retention of a targeted tissue sample.
摘要翻译：本发明的实施例包括用于获得组织的装置，包括近侧致动器和具有第一和第二端部执行器的远端组件。第一和第二末端执行器包括第一和第二末端执行器内的内表面中的至少一个元件的特征，用于帮助捕获和保持靶组织样本。

4. 发明申请

US20100318119A1 BIOPSY FORCEPS ASSEMBLIES 有权
标题翻译：生物武器组装
公开(公告)号：US20100318119A1
公开(公告)日：2010-12-16
申请号：US12816248
申请日：2010-06-15
申请人： Tyler Timberlake , Changqing Li , Otto Anderhub , Douglas M. Bontrager , Gerardo Martin , Robert B. DeVries
发明人： Tyler Timberlake , Changqing Li , Otto Anderhub , Douglas M. Bontrager , Gerardo Martin , Robert B. DeVries
IPC分类号： A61B17/28
CPC分类号： A61B10/00 , A61B10/06 , A61B2017/00353 , A61B2017/2939 , A61B2017/320064
摘要： Embodiments of the invention include devices for obtaining tissue including a proximal actuator and a distal assembly having first and second end effectors. The first and second end effectors include the features of at least one element within the inner surface either of the first and second end effectors for aiding in the capture and retention of a targeted tissue sample.
摘要翻译：本发明的实施例包括用于获得组织的装置，包括近侧致动器和具有第一和第二端部执行器的远端组件。第一和第二末端执行器包括第一和第二末端执行器内的内表面中的至少一个元件的特征，用于帮助捕获和保持靶组织样本。

5. 发明申请

US20130085412A1 BIOPSY FORCEPS ASSEMBLIES 有权
标题翻译：生物武器组装
公开(公告)号：US20130085412A1
公开(公告)日：2013-04-04
申请号：US13658646
申请日：2012-10-23
申请人： Tyler Timberlake , Changqing Li , Otto Anderhub , Douglas M. Bontrager , Gerardo Martin , Robert B. DeVries
发明人： Tyler Timberlake , Changqing Li , Otto Anderhub , Douglas M. Bontrager , Gerardo Martin , Robert B. DeVries
IPC分类号： A61B10/06
CPC分类号： A61B10/00 , A61B10/06 , A61B2017/00353 , A61B2017/2939 , A61B2017/320064
摘要： Embodiments of the invention include devices for obtaining tissue including a proximal actuator and a distal assembly having first and second end effectors. The first and second end effectors include the features of at least one element within the inner surface either of the first and second end effectors for aiding in the capture and retention of a targeted tissue sample.
摘要翻译：本发明的实施例包括用于获得组织的装置，包括近侧致动器和具有第一和第二端部执行器的远端组件。第一和第二末端执行器包括第一和第二末端执行器内的内表面中的至少一个元件的特征，用于帮助捕获和保持靶组织样本。

6. 发明授权

US09078997B2 Catheter assembly including coiled internal bolster 有权
公开(公告)号：US09078997B2
公开(公告)日：2015-07-14
申请号：US12079954
申请日：2008-03-29
申请人： Changqing Li , Ken Brown , Alan Sundheimer , Boyd Colvin
发明人： Changqing Li , Ken Brown , Alan Sundheimer , Boyd Colvin
IPC分类号： A61M25/04 , A61M25/00 , A61M27/00 , A61M1/28 , A61M3/02 , A61J15/00 , A61B17/34
CPC分类号： A61M25/04 , A61B17/3415 , A61J15/0023 , A61J15/0038 , A61M1/285 , A61M3/02 , A61M3/0225 , A61M25/0015 , A61M25/0017 , A61M25/0041 , A61M27/008 , A61M2025/0063
摘要： A catheter assembly including a medical catheter and an internal bolster. In a preferred embodiment, the catheter is an elongated, tubular structure preferably made of a flexible, biocompatible material. The catheter is shaped to include a generally cylindrical wall terminating in a first end and in a second end, the wall coaxially surrounding and defining a longitudinal bore preferably used to convey fluids, such as food and/or medications, to a patient in need thereof. The internal bolster is an elongated, semi-tubular structure preferably made of a flexible, biocompatible material. The bolster is resiliently and reversibly transformable between a generally planar shape, when at rest, and a straightened shape, when forcibly unfurled. The bolster has an inner end and an outer end, the inner end being generally centrally located. The inner end of the bolster is insert-molded around the first end of the catheter, with the catheter and the bolster being oriented relative to one another so that the longitudinal axis of the catheter extends generally perpendicularly to the plane of the bolster in its coiled state, with the open, semi-tubular structure of the bolster facing away from the catheter.

7. 外观设计

USD490890S1 Percutaneous endoscopic gastronomy device 失效
标题翻译：经皮内镜美食装置
公开(公告)号：USD490890S1
公开(公告)日：2004-06-01
申请号：US29181032
申请日：2003-05-02
申请人： Changqing Li
设计人： Changqing Li

8. 发明授权

US08343760B2 p53 activator peptides 有权
标题翻译： p53激活肽
公开(公告)号：US08343760B2
公开(公告)日：2013-01-01
申请号：US12996196
申请日：2009-06-05
申请人： Wuyuan Lu , Davide Zella , Min Liu , Changqing Li
发明人： Wuyuan Lu , Davide Zella , Min Liu , Changqing Li
IPC分类号： C12N5/00 , C12N15/00 , C12P21/06 , C07H21/04 , A61K38/00 , A61K38/04
CPC分类号： C07K14/43522
摘要： The present invention relates to novel polypeptides that activate p53, and the polynucleotides encoding these p53 activator peptides. The present invention also relates to pharmaceutical compositions comprising the p53 activator peptides as well as methods of treating abnormal conditions, such as malignant tumors, with the methods comprising administering the pharmaceutical compositions of the present invention to a subject in need of treatment thereof.
摘要翻译：本发明涉及活化p53的新型多肽，以及编码这些p53活化肽的多核苷酸。本发明还涉及包含p53激活剂肽的药物组合物以及治疗异常病症如恶性肿瘤的方法，包括将本发明的药物组合物施用于需要治疗的受试者。

9. 发明申请

US20070140786A1 TUBE CONNECTION JOINT AND METHOD OF FORMING SAME 有权
标题翻译：管连接接头及其形成方法
公开(公告)号：US20070140786A1
公开(公告)日：2007-06-21
申请号：US11565568
申请日：2006-11-30
申请人： Herbert Sundheimer , Christopher Benning , Changqing Li
发明人： Herbert Sundheimer , Christopher Benning , Changqing Li
IPC分类号： F16B12/36
CPC分类号： F16B11/008 , A61M39/12 , A61M2039/1027 , B29C65/48 , B29C65/4835 , B29C65/4865 , B29C66/112 , B29C66/114 , B29C66/1162 , B29C66/534 , B29C66/71 , B29K2083/00 , B29L2023/007 , F16L33/34 , Y10T403/477 , Y10T403/52 , Y10T403/55 , Y10T403/559 , B29K2023/065
摘要： A connection joint (20) is described that is formed by inserting a plastic connector (10) into the end of a silicone tube (14). The connector includes a plurality of barbs (12). A reinforcing agent (16) is placed between each of the barbs (12) of the connector (10). An adhesive (18) is injected between the tube (14), the reinforcing agents (16) and the connector (10). The adhesive (18) is then cured at a predetermined temperature for a predetermined time in order to solidify the connection joint (20).
摘要翻译：描述了通过将塑料连接器（10）插入硅树脂管（14）的端部而形成的连接接头（20）。连接器包括多个倒钩（12）。在连接器（10）的每个倒钩（12）之间放置增强剂（16）。在管（14），增强剂（16）和连接器（10）之间注入粘合剂（18）。然后将粘合剂（18）在预定温度下固化预定时间，以固化连接接头（20）。

10. 发明申请

US20090182272A1 Medical catheter assembly including multi-piece connector 失效
标题翻译：医用导管组件包括多片连接器
公开(公告)号：US20090182272A1
公开(公告)日：2009-07-16
申请号：US12383354
申请日：2009-03-23
申请人： Changqing Li , Gray Wood , Herbert Alan Sundheimer , Laddvanh Bouphvichith , Patrice A. Weststrate , Laurence D. Brenner
发明人： Changqing Li , Gray Wood , Herbert Alan Sundheimer , Laddvanh Bouphvichith , Patrice A. Weststrate , Laurence D. Brenner
IPC分类号： A61M25/16 , A61M29/00
CPC分类号： A61J15/0026 , A61J15/0019 , A61J15/0034 , A61M25/0014 , A61M39/0247 , A61M39/10 , A61M39/1011 , A61M39/12 , A61M2039/1027 , A61M2039/1033 , A61M2039/1077 , F16L33/225
摘要： A medical catheter assembly including a multi-piece connector. In one embodiment, the medical catheter assembly is a PEG implanting assembly comprising a tubular dilator and a silicone feeding tube having an internal bolster at its rear end. The assembly also comprises a multi-piece connector comprising an inner ring, a fitting and an outer ring. The inner ring has an outer diameter greater than the inner diameter of the feeding tube and is coaxially disposed within the feeding tube by a friction-fit. The fitting comprises a front portion, an intermediate portion and a rear portion, the intermediate portion including a shoulder having an outer diameter greater than the inner diameter of the feeding tube. The front portion of the fitting is inserted through the rear end of the dilator and is secured to the dilator by a plurality of barbs. The shoulder and the rear portion of the fitting are inserted into the feeding tube through its rear end, with the rear portion of the fitting being inserted into the inner ring and secured thereto by mating threads. The outer ring is inserted over the feeding tube and is positioned between the shoulder and the inner ring, the outer ring being sized to securely retain the feeding tube between the outer ring and the inner ring and between the outer ring and the shoulder.
摘要翻译：一种医疗导管组件，包括多片连接器。在一个实施例中，医疗导管组件是PEG植入组件，其包括管状扩张器和在其后端具有内部枕垫的硅胶进料管。组件还包括多片连接器，其包括内环，配件和外环。内圈的外径大于进料管的内径，并通过摩擦配合同轴地设置在进料管内。该配件包括前部，中间部分和后部，中间部分包括具有大于供给管内径的外径的肩部。配件的前部插入穿过扩张器的后端，并通过多个倒钩固定到扩张器。配件的肩部和后部通过其后端插入进料管中，配件的后部插入内圈并通过配合螺纹固定在其上。外环被插入进料管上并且位于肩部和内圈之间，外圈的尺寸设计成将进料管牢固地保持在外圈和内圈之间以及在外圈和肩部之间。

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