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1. 发明授权

US06723047B1 Volition induction apparatus and input/output apparatus which use optical measuring instrument, and recording medium 有权
标题翻译：使用光学测量仪器和记录介质的感应装置和输入/输出装置
公开(公告)号：US06723047B1
公开(公告)日：2004-04-20
申请号：US10009187
申请日：2001-12-07
申请人： Tsuyoshi Yamamoto , Atsushi Maki , Yoshitoshi Ito , Yuichi Yamashita , Hideaki Koizumi
发明人： Tsuyoshi Yamamoto , Atsushi Maki , Yoshitoshi Ito , Yuichi Yamashita , Hideaki Koizumi
IPC分类号： A61B500
CPC分类号： G06F3/015 , A61B5/486 , A63F2250/26 , Y10S128/905
摘要： It has long been unclear in what degree the brain should be activated and how much the blood volume should be varied for controlling a signal by measuring the concentration of metabolic substance in the tissue or change of concentration thereof using the light and by using the result of measurement. The present invention provides an optical measuring system which can present the concentration of metabolic substance in the tissue which may be detected with a subject by itself or the target value of change of the concentration. Thereby, it is now possible for the subject by itself to more easily detect and control the concentration of metabolic substance in the tissue or change of concentration thereof. As a result, cerebral information can be extracted in direct to realize various applications such as control of the game machines and welfare facilities.
摘要翻译：长期以来，不清楚大脑应该被激活的程度以及通过使用光测量组织中代谢物质的浓度或其浓度的变化来控制信号来改变血容量，并且通过使用测量。本发明提供一种光学测量系统，其可以呈现组织中代谢物质的浓度，其可以由受试者自身检测或目标浓度变化值。因此，现在可以使受试者本身更容易地检测和控制组织中代谢物质的浓度或其浓度的变化。因此，可以直接提取脑信息，实现游戏机和福利设施的控制等各种应用。

2. 发明授权

US06321110B1 Device for controlling equipment by using signals from a living body 失效
标题翻译：通过使用生物体信号控制设备的装置
公开(公告)号：US06321110B1
公开(公告)日：2001-11-20
申请号：US09385419
申请日：1999-08-30
申请人： Yoshitoshi Ito , Hideaki Koizumi , Atsushi Maki , Yuichi Yamashita , Tsuyoshi Yamamoto
发明人： Yoshitoshi Ito , Hideaki Koizumi , Atsushi Maki , Yuichi Yamashita , Tsuyoshi Yamamoto
IPC分类号： A61B600
CPC分类号： G06F3/015
摘要： A device for controlling equipment includes a light projector adapted to project light onto a head of a living body, a light collecting device for collecting the light having passed through the head from the light projector, a light measuring device for measuring an intensity of the light collected by the light collecting device, a memory device for storing a previous history of changes of the intensity of the light measured by the light measuring device, a signal judging circuit for judging if both the intensity of the light measured by the light measuring device and the previous history of changes of the intensity of the light satisfy a predetermined condition, a display device for displaying the intensity of the light measured by the light measuring device and a result obtained by the signal judging circuit, and a control signal generating circuit for generating a control signal to be supplied to an external equipment if the predetermined condition is satisfied.
摘要翻译：一种用于控制设备的装置，包括适用于将光投射到生物体的头部上的光投射器，用于收集从光投影仪通过头部的光的光收集装置，用于测量光强度的光测量装置由光收集装置收集的存储装置，用于存储由光测量装置测量的光的强度变化的先前历史的存储装置，用于判断由光测量装置测量的光的强度和光的强度变化的先前历史满足预定条件，用于显示由光测量装置测量的光的强度的显示装置和由信号判断电路获得的结果的控制信号产生电路，如果满足预定条件，则提供给外部设备的控制信号。

3. 发明授权

US06895269B2 Device for controlling equipment by using signals from a living body 失效
标题翻译：通过使用生物体信号控制设备的装置
公开(公告)号：US06895269B2
公开(公告)日：2005-05-17
申请号：US09987334
申请日：2001-11-14
申请人： Yoshitoshi Ito , Hideaki Koizumi , Atsushi Maki , Yuichi Yamashita , Tsuyoshi Yamamoto
发明人： Yoshitoshi Ito , Hideaki Koizumi , Atsushi Maki , Yuichi Yamashita , Tsuyoshi Yamamoto
IPC分类号： G06F3/00 , G06F3/01 , A61B6/00
CPC分类号： G06F3/015
摘要： A device for controlling equipment includes at least one light projector adapted to project light onto a head of a living body. A light collecting section for collecting the light having passed through the head, a light measuring section for measuring an intensity of the light collected by the light collecting section, a memory section for storing a previous history of changes of the intensity of the light measured, a signal judging section for judging if both the intensity of the light measured by said light measuring section and the previous history of changes of the intensity of the light satisfy a predetermined condition, a displaying section for displaying the intensity of the light measured and a result obtained by the signal judging section, and a control signal generating section for generating a control signal for external equipment.
摘要翻译：一种用于控制设备的设备包括至少一个适于将光投射到生物体的头部上的投影仪。用于收集通过头部的光的聚光部分，用于测量由聚光部分收集的光的强度的光测量部分，用于存储测量的光的强度变化的先前历史的存储部分，信号判断部分，用于判断由所述光测量部分测量的光的强度和光的强度变化的先前历史是否都满足预定条件;显示部分，用于显示所测量的光的强度和结果由信号判定部获得的控制信号生成部，生成外部设备的控制信号。

4. 发明授权

US07286870B2 Optical system for measuring metabolism in a body and imaging method 有权
标题翻译：用于测量身体代谢的光学系统和成像方法
公开(公告)号：US07286870B2
公开(公告)日：2007-10-23
申请号：US09900144
申请日：2001-07-09
申请人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
发明人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
IPC分类号： A61B6/00
CPC分类号： A61B5/0059 , A61B5/0042 , A61B5/055 , A61B5/14552 , A61B5/14553 , A61B5/18 , A61B5/6814 , A61B5/7207 , A61B5/7228 , A61B6/03 , A61B6/507 , A61B2562/0219 , A61B2562/0233 , A61B2562/046
摘要： In an optical measurement system and imaging method adapted to measure in vivo information in a living body without harming the living body, light rays of a plurality of wavelengths which are modulated in intensity with a plurality of different frequencies are irradiated on a plurality of irradiation positions on the surface of a living body, and time-variable changes in living body transmitting light intensity levels corresponding to the respective wavelengths and the respective irradiation positions are measured at different positions on the surface of the living body. Light is utilized to image the results of the measurements, in which the measuring time is shortened by estimating fluctuation attributable to the living body, and the presence or absence of a change in measured signal can be decided easily by displaying an estimation signal and a measured signal at a time.
摘要翻译：在适于测量活体内的体内信息而不损害生物体的光学测量系统和成像方法中，以多个不同频率强度调制的多个波长的光线照射在多个照射位置在生物体的表面上，在生物体的表面的不同位置测量发射对应于各个波长和各个照射位置的光强度水平的生物体的随时间变化。光被用于对测量结果进行成像，其中通过估计归因于生物体的波动来缩短测量时间，并且可以通过显示估计信号和测量的信号来容易地确定测量信号的变化的存在或不存在信号一次。

5. 发明授权

US08050744B2 Optical system for measuring metabolism in a body and imaging method 有权
标题翻译：用于测量身体代谢的光学系统和成像方法
公开(公告)号：US08050744B2
公开(公告)日：2011-11-01
申请号：US11037338
申请日：2005-01-19
申请人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
发明人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
IPC分类号： A61B6/00 , A61B5/00
CPC分类号： A61B5/0059 , A61B5/0042 , A61B5/055 , A61B5/14552 , A61B5/14553 , A61B5/18 , A61B5/6814 , A61B5/7207 , A61B5/7228 , A61B6/03 , A61B6/507 , A61B2562/0219 , A61B2562/0233 , A61B2562/046
摘要： In an optical measurement system and imaging method adapted to measure in vivo information in a living body without harming the living body, light rays of a plurality of wavelengths which are modulated in intensity with a plurality of different frequencies are irradiated on a plurality of irradiation positions on the surface of a living body, and time-variable changes in living body transmitting light intensity levels corresponding to the respective wavelengths and the respective irradiation positions are measured at different positions on the surface of the living body. Light is utilized to image the results of the measurements, in which the measuring time is shortened by estimating fluctuation attributable to the living body, and the presence or absence of a change in measured signal can be decided easily by displaying an estimation signal and a measured signal at a time.
摘要翻译：在适于测量活体内的体内信息而不损害生物体的光学测量系统和成像方法中，以多个不同频率强度调制的多个波长的光线照射在多个照射位置在生物体的表面上，在生物体的表面的不同位置测量发射对应于各个波长和各个照射位置的光强度水平的生物体的随时间变化。光被用于对测量结果进行成像，其中通过估计归因于生物体的波动来缩短测量时间，并且可以通过显示估计信号和测量的信号来容易地确定测量信号的变化的存在或不存在信号一次。

6. 发明授权

US5803909A Optical system for measuring metabolism in a body and imaging method 失效
标题翻译：用于测量身体代谢的光学系统和成像方法
公开(公告)号：US5803909A
公开(公告)日：1998-09-08
申请号：US539871
申请日：1995-10-06
申请人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
发明人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
IPC分类号： A61B5/00 , A61B5/05 , A61B5/055 , A61B5/18 , A61B6/00 , A61B6/03
CPC分类号： A61B5/0059 , A61B5/0042 , A61B5/14552 , A61B5/14553 , A61B5/18 , A61B5/6814 , A61B2562/0219 , A61B2562/0233 , A61B2562/046 , A61B5/055 , A61B5/7207 , A61B5/7228 , A61B6/03 , A61B6/507
摘要： Light rays of a plurality of wavelengths which are modulated in intensity with a plurality of different frequencies are irradiated on a plurality of irradiation positions on the surface of a living body, and time-variable changes in living body transmitting light intensity levels corresponding to the respective wavelengths and the respective irradiation positions are measured at different positions on the surface Changes in concentration values of absorbers are determined from the living body transmitting light intensity levels and a measuring point is set on a perpendicular extending through an intermediate point between the incident point and each detection point to image a function of the living body. The measuring time is shortened by estimating fluctuation attributable to the living body, and a local change in hemodynamic movement can be measured by detecting light rays transmitting through the interior of the living body by light detection at two different sites (equidistant from the light incident point) on a subject and by separating only the local change in hemodynamic movement from an overall change in hemodynamic movement in the living body in accordance with a logarithmic difference between the two detection signals.
摘要翻译：以多个不同频率强度调制的多个波长的光线照射在生物体的表面上的多个照射位置上，并且生物体的时间变化透射与各个相对应的光强度水平波长和各个照射位置在表面上的不同位置被测量吸收体的浓度值的变化由生物体透射光强度水平确定，并且测量点设置在延伸穿过入射点和每个之间的中间点的垂直检测点成像生物体的功能。通过估计生物体的波动来缩短测量时间，并且可以通过在两个不同位置（等于光入射点的光检测）检测透射通过生物体内部的光线来测量血液动力学运动的局部变化），并且根据两个检测信号之间的对数差异仅分离血液动力学运动的局部变化与生物体中的血液动力学运动的总体变化。

7. 发明申请

US20050171440A1 Optical system for measuring metabolism in a body and imaging method 有权
公开(公告)号：US20050171440A1
公开(公告)日：2005-08-04
申请号：US11037338
申请日：2005-01-19
申请人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
发明人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
IPC分类号： A61B5/00 , A61B5/05 , A61B5/055 , A61B5/18 , A61B6/00 , A61B6/03
CPC分类号： A61B5/0059 , A61B5/0042 , A61B5/055 , A61B5/14552 , A61B5/14553 , A61B5/18 , A61B5/6814 , A61B5/7207 , A61B5/7228 , A61B6/03 , A61B6/507 , A61B2562/0219 , A61B2562/0233 , A61B2562/046
摘要： In an optical measurement system and imaging method adapted to measure in vivo information in a living body without harming the living body, light rays of a plurality of wavelengths which are modulated in intensity with a plurality of different frequencies are irradiated on a plurality of irradiation positions on the surface of a living body, and time-variable changes in living body transmitting light intensity levels corresponding to the respective wavelengths and the respective irradiation positions are measured at different positions on the surface of the living body. Light is utilized to image the results of the measurements, in which the measuring time is shortened by estimating fluctuation attributable to the living body, and the presence or absence of a change in measured signal can be decided easily by displaying an estimation signal and a measured signal at a time.

8. 发明授权

US06282438B1 Optical system for measuring metabolism in a body and imaging method 失效
标题翻译：用于测量身体代谢的光学系统和成像方法
公开(公告)号：US06282438B1
公开(公告)日：2001-08-28
申请号：US09203610
申请日：1998-12-02
申请人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
发明人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
IPC分类号： A61B600
CPC分类号： A61B5/0059 , A61B5/0042 , A61B5/055 , A61B5/14552 , A61B5/14553 , A61B5/18 , A61B5/6814 , A61B5/7207 , A61B5/7228 , A61B6/03 , A61B6/507 , A61B2562/0219 , A61B2562/0233 , A61B2562/046
摘要： Light rays of a plurality of wavelengths which are modulated in intensity with a plurality of different frequencies are irradiated on a plurality of irradiation positions on the surface of a living body, and time-variable changes in living body transmitting light intensity levels corresponding to the respective wavelengths and the respective irradiation positions are measured at different positions on the surface of the living body. After completion of the measurement or during the measurement, changes in concentration values of absorbers in the living body are determined from the living body transmitting light intensity levels of the plurality of wavelengths detected at the respective detection points and a measuring point is set on a perpendicular extending through an intermediate point between the incident point and each detection point so as to image a function of the living body. In living body optical measurement system and method, the measuring time is shortened by estimating fluctuation attributable to the living body, the presence or absence of a change in measured signal can be decided easily by displaying an estimation signal and a measured signal at a time, and a local change in. hemodynamic movement can be measured by detecting light rays transmitting through the interior of the living body by the two light detectors disposed at different two sites (equidistant from the light incident point) on a subject and by separating only the local change in hemodynamic movement from an overall change in hemodynamic movement in the living body in accordance with a logarithmic difference between the two detection signals.
摘要翻译：以多个不同频率强度调制的多个波长的光线照射在生物体的表面上的多个照射位置上，并且生物体的时间变化透射与各个相对应的光强度水平波长和各个照射位置在生物体的表面上的不同位置处被测量。在测量完成之后或在测量期间，生物体中的吸收体的浓度值的变化是根据在各个检测点处检测到的多个波长的光强度水平来发射的，并且将测量点设定在垂直方向延伸穿过入射点和每个检测点之间的中间点，以便对活体的功能进行成像。在生物体光学测量系统和方法中，通过估计归因于生物体的波动来缩短测量时间，通过一次显示估计信号和测量信号可以容易地确定测量信号的变化是否存在，并且可以通过检测设置在被摄体上不同的两个位置（等于光入射点的位置）的两个光检测器检测通过生物体的内部的光线，并且仅分离本地根据两个检测信号之间的对数差异，从生物体的血液动力学运动的总体变化中改变血流动力学运动。

9. 发明授权

US07440794B2 Optical system for measuring metabolism in a body and imaging method 有权
标题翻译：用于测量身体代谢的光学系统和成像方法
公开(公告)号：US07440794B2
公开(公告)日：2008-10-21
申请号：US11037282
申请日：2005-01-19
申请人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
发明人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
IPC分类号： A61B5/00
CPC分类号： A61B5/0059 , A61B5/0042 , A61B5/055 , A61B5/14552 , A61B5/14553 , A61B5/18 , A61B5/6814 , A61B5/7207 , A61B5/7228 , A61B6/03 , A61B6/507 , A61B2562/0219 , A61B2562/0233 , A61B2562/046
摘要： In an optical measurement system and imaging method adapted to measure in vivo information in a living body without harming the living body, light rays of a plurality of wavelengths which are modulated in intensity with a plurality of different frequencies are irradiated on a plurality of irradiation positions on the surface of a living body, and time-variable changes in living body transmitting light intensity levels corresponding to the respective wavelengths and the respective irradiation positions are measured at different positions on the surface of the living body. Light is utilized to image the results of the measurements, in which the measuring time is shortened by estimating fluctuation attributable to the living body, and the presence or absence of a change in measured signal can be decided easily by displaying an estimation signal and a measured signal at a time.
摘要翻译：在适于测量活体内的体内信息而不损害生物体的光学测量系统和成像方法中，以多个不同频率强度调制的多个波长的光线照射在多个照射位置在生物体的表面上，在生物体的表面的不同位置测量发射对应于各个波长和各个照射位置的光强度水平的生物体的随时间变化。光被用于对测量结果进行成像，其中通过估计归因于生物体的波动来缩短测量时间，并且可以通过显示估计信号和测量的信号来容易地确定测量信号的变化的存在或不存在信号一次。

10. 发明授权

US07715904B2 Optical system for measuring metabolism in a body and imaging method 有权
标题翻译：用于测量身体代谢的光学系统和成像方法
公开(公告)号：US07715904B2
公开(公告)日：2010-05-11
申请号：US11037339
申请日：2005-01-19
申请人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
发明人： Atsushi Maki , Hideaki Koizumi , Fumio Kawaguchi , Yuichi Yamashita , Yoshitoshi Ito
IPC分类号： A61B6/00 , A61B5/00
CPC分类号： A61B5/0059 , A61B5/0042 , A61B5/055 , A61B5/14552 , A61B5/14553 , A61B5/18 , A61B5/6814 , A61B5/7207 , A61B5/7228 , A61B6/03 , A61B6/507 , A61B2562/0219 , A61B2562/0233 , A61B2562/046
摘要： In an optical measurement system and imaging method adapted to measure in vivo information in a living body without harming the living body, light rays of a plurality of wavelengths which are modulated in intensity with a plurality of different frequencies are irradiated on a plurality of irradiation positions on the surface of a living body, and time-variable changes in living body transmitting light intensity levels corresponding to the respective wavelengths and the respective irradiation positions are measured at different positions on the surface of the living body. Light is utilized to image the results of the measurements, in which the measuring time is shortened by estimating fluctuation attributable to the living body, and the presence or absence of a change in measured signal can be decided easily by displaying an estimation signal and a measured signal at a time.
摘要翻译：在适于测量活体内的体内信息而不损害生物体的光学测量系统和成像方法中，以多个不同频率强度调制的多个波长的光线照射在多个照射位置在生物体的表面上，在生物体的表面的不同位置测量发射对应于各个波长和各个照射位置的光强度水平的生物体的随时间变化。光被用于对测量结果进行成像，其中通过估计归因于生物体的波动来缩短测量时间，并且可以通过显示估计信号和测量的信号来容易地确定测量信号的变化的存在或不存在信号一次。

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