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1. 发明申请

US20070135423A1 E-fluoro-4-(pyridin-2-yl)-piperidine-1-carboxamide derivatives and related compounds which modulate the function of the vanilloid-1 receptor (vr1) for the treatment of pain 审中-公开
标题翻译： E-fluor-4-（吡啶-2-基） - 哌啶-1-甲酰胺衍生物和调节香草素-1受体（vr1）功能的相关化合物用于治疗疼痛
公开(公告)号：US20070135423A1
公开(公告)日：2007-06-14
申请号：US10577585
申请日：2004-10-27
申请人： Tracy Bayliss , Rebecca Brown , Frank Burkamp , Brian Jones , Joseph Neduvelil
发明人： Tracy Bayliss , Rebecca Brown , Frank Burkamp , Brian Jones , Joseph Neduvelil
IPC分类号： A61K31/541 , A61K31/5377 , A61K31/496 , A61K31/4545 , A61K31/454 , C07D417/02 , C07D413/02 , C07D401/02
CPC分类号： C07D451/04 , C07D401/04
摘要： Compounds of formula (I): wherein: A1 is phenyl, a six-membered aromatic heterocycle containing one, two or three nitrogen atoms, or a five-membered aromatic heterocycle containing up to four heteroatoms chosen from O, N and S, at most one heteroatom being O or S; A2 is phenyl, a six-membered aromatic heterocycle containing one, two or three nitrogen atoms, or a five-membered aromatic heterocycle containing up to four heteroatoms chosen from O, N and S, at most one heteroatom being O or S; L is a bond or C1-6alkylene; R1 and R2 independently chosen from hydrogen and C1-6alkyl or R1 and R2 may, together, form a methylene or ethylene bridge; W is halogen, C1-6alkyl, haloC1-6alkyl, C1-6alkoxy or haloC1-6alkoxy; X is O, S or NR3 or X, together with the atom to which it is attached, and Y, form an unsaturated five-membered ring together with A2; Y is a bond, C1-4alkylene, NH or NH(CH2)1-3; or a pharmaceutically acceptable salt thereof; other substituents are defined in claim 1; which are useful as therapeutic compounds, particularly in the treatment of pain and other conditions ameliorated by the modulation of the function of the vanilloid-1 receptor (VR1).
摘要翻译：式（I）化合物：其中：A 1是苯基，含有一个，两个或三个氮原子的六元芳族杂环，或含有至多四个选自以下的杂原子的五元芳族杂环： O，N和S，最多一个杂原子是O或S; A 2是苯基，含有一个，两个或三个氮原子的六元芳族杂环，或含有至多四个选自O，N和S的杂原子的五元芳族杂环，最多一个杂原子是O或S; L是键或C 1-6 - 亚烷基; R 1和R 2独立地选自氢和C 1-6烷基或R 1和R 2 > 2可以一起形成亚甲基或乙烯桥; W是卤素，C 1-6烷基，卤代C 1-6烷基，C 1-6 - 烷氧基或卤代C 1-6 烷氧基; X是O，S或NR 3或X，连同其所连接的原子，Y与A 2形成不饱和五元环; Y是一个键，C 1-4亚烷基，NH或NH（CH 2 CH 2）1-3。或其药学上可接受的盐; 其它取代基如权利要求1中所定义; 其可用作治疗化合物，特别是用于治疗通过调节香草素-1受体（VR1）的功能而改善的疼痛和其它病症。

2. 发明申请

US20070135454A1 Bicyclic pyrimidin-4(3h)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1-receptor(vr1) 审中-公开
标题翻译：调节香草醇-1-受体（vr1）功能的双环嘧啶-4（3h） - 酮及其类似物和衍生物
公开(公告)号：US20070135454A1
公开(公告)日：2007-06-14
申请号：US10578855
申请日：2004-11-12
申请人： Tracy Bayliss , Gregory Hollingworth , Rebecca Jarvis , Brian Jones , Timothy Sparey
发明人： Tracy Bayliss , Gregory Hollingworth , Rebecca Jarvis , Brian Jones , Timothy Sparey
IPC分类号： A61K31/519 , C07D498/02 , C07D491/02 , C07D487/02
CPC分类号： C07D473/22 , C07D471/04 , C07D473/18 , C07D473/24 , C07D495/04 , C07D513/04
摘要： Compounds of formula (I); which are useful as therapeutic compounds, particularly in the treatment of pain and other conditions ameliorated by the modulation of the function of the vanilloid-1 receptor (VR1).
摘要翻译：式（I）化合物; 其可用作治疗化合物，特别是用于治疗通过调节香草素-1受体（VR1）的功能而改善的疼痛和其它病症。

3. 发明申请

US20060229307A1 Substituted-1-phthalazinamines as vr-1 antagonists 失效
标题翻译：取代的1-酞嗪胺作为vr-1拮抗剂
公开(公告)号：US20060229307A1
公开(公告)日：2006-10-12
申请号：US10555235
申请日：2004-04-05
申请人： Peter Blurton , Frank Burkamp , Stephen Fletcher , Brian Jones , Edward Mclver
发明人： Peter Blurton , Frank Burkamp , Stephen Fletcher , Brian Jones , Edward Mclver
IPC分类号： A61K31/5377 , A61K31/503 , C07D487/02
CPC分类号： C07D401/04 , C07D403/04 , C07D471/04
摘要： The present invention provides a compound of formula (I): in which Ar and R1 are phenyl or a heteroaromatic group, R2 is generally hydrogen, R3 is hydrogen or alkyl and X, Y and Z are generally CH or N as VR-1 antagonists; or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising it; its use in therapy; use of it to manufacture medicaments to treat pain or inflammation; and methods of treating pain or inflammation.
摘要翻译：本发明提供式（I）化合物：其中Ar和R 1是苯基或杂芳基，R 2通常是氢，R 3 H，Y和Z通常为CH或N作为VR-1拮抗剂; 或其药学上可接受的盐; 包含它的药物组合物; 其用于治疗; 使用它来制造治疗疼痛或炎症的药物; 以及治疗疼痛或炎症的方法。

4. 发明公开

US20230330708A1 TOWEL INCLUDING SCRUBBING ELEMENT 审中-公开
公开(公告)号：US20230330708A1
公开(公告)日：2023-10-19
申请号：US17659149
申请日：2022-04-13
申请人： Brian Jones
发明人： Brian Jones
IPC分类号： B08B1/00 , A47L25/00
CPC分类号： B08B1/006 , A47L25/00
摘要： An example towel may include a main body and a scrubbing element coupled to a first side of the main body. The main body may include a first material. The scrubbing element may include a second material that may be different from the first material.

5. 发明授权

US09550315B2 Delivering liquid additive 有权
标题翻译：提供液体添加剂
公开(公告)号：US09550315B2
公开(公告)日：2017-01-24
申请号：US13263298
申请日：2010-03-26
申请人： Brian Jones , Keith Bell , Andrew Stuart Overend , Mark Frost
发明人： Brian Jones , Keith Bell , Andrew Stuart Overend , Mark Frost
IPC分类号： B29C31/10 , B01F3/12 , B01F11/02 , B29B7/94 , B29K105/00
CPC分类号： B29C31/10 , B01F3/1242 , B01F11/0266 , B29B7/94 , B29K2105/0005
摘要： A reservoir assembly (40) comprises a container (4), a support assembly (42) on which the container (4) is mounted and fixed and a rotary electric vibrator device (44) coupled to the support assembly (42). The container holds a shear thinning additive for a plastics material. The reservoir assembly is arranged so that on operation of the device (44), an appropriate frequency and amplitude of vibration is applied to the container (4) and, therefore, its contents. As a result, a liquid dispersion in the container is shear thinned and recovery of dispersion from the container is increased.
摘要翻译：储存器组件（40）包括容器（4），支撑组件（42），容器（4）安装在其上并固定在其上，以及联接到支撑组件（42）的旋转电动振动器装置（44）。容器容纳用于塑料材料的剪切稀化添加剂。储存器组件被布置成使得在装置（44）的操作上，将适当的振动频率和振幅施加到容器（4），并因此施加其内容物。结果，容器中的液体分散体被剪切变薄，并且从容器中回收分散体。

6. 发明授权

US09260233B2 Formulations 有权
标题翻译：配方
公开(公告)号：US09260233B2
公开(公告)日：2016-02-16
申请号：US13833710
申请日：2013-03-15
申请人： Brian Jones , John Pickles , Harry Baker
发明人： Brian Jones , John Pickles , Harry Baker
IPC分类号： B65D25/08 , B65D77/06 , B65B3/04 , B65D5/40 , B01F9/00 , B01F15/00
CPC分类号： B01F9/0023 , B01F9/0001 , B01F15/0074 , B01F15/00753 , B65B3/04 , B65D5/40 , B65D77/062 , B65D77/065
摘要： A receptacle includes a cardboard box in which is arranged a plastics container. A first securement element associated with the plastics container is positioned in a gap defined by the cardboard of the box thereby to restrict movement of the container within the box.
摘要翻译：容器包括纸板箱，其中布置有塑料容器。与塑料容器相关联的第一固定元件定位在由盒的纸板限定的间隙中，从而限制容器在盒内的移动。

7. 发明授权

US08613388B2 Check accepting and cash dispensing automated banking machine system and method 有权
标题翻译：检查接收和现金分发自动银行机系统和方法
公开(公告)号：US08613388B2
公开(公告)日：2013-12-24
申请号：US13428007
申请日：2012-03-23
申请人： Thomas A. VanKirk , Jon E. Washington , Brian Jones , William D. Beskitt , Harry Thomas Graef , David A. Peters , Damon J. Blackford , Dale H. Blackson , Edward L. Laskowski , Songtao Ma , Tim Crews , Wayne Warren , Martin J. Brown , Todd Galloway , Kenneth Turocy , Douglas T. Dominick , Jasen J. Smolk , Brian E. Lucas , Bradley Lightner , James Meek , Robert W. Barnett , Mike Ryan , James R. Kay , Mark A. Ward , Victor Bell , William McCarthy , Matthew Pahl , Keith Carpenter , Laura Drozda
发明人： Thomas A. VanKirk , Jon E. Washington , Brian Jones , William D. Beskitt , Harry Thomas Graef , David A. Peters , Damon J. Blackford , Dale H. Blackson , Edward L. Laskowski , Songtao Ma , Tim Crews , Wayne Warren , Martin J. Brown , Todd Galloway , Kenneth Turocy , Douglas T. Dominick , Jasen J. Smolk , Brian E. Lucas , Bradley Lightner , James Meek , Robert W. Barnett , Mike Ryan , James R. Kay , Mark A. Ward , Victor Bell , William McCarthy , Matthew Pahl , Keith Carpenter , Laura Drozda
IPC分类号： G07F19/00
CPC分类号： G06Q20/042 , G06Q20/1085 , G07D11/0084 , G07F19/20
摘要： An automated banking machine operates responsive to data read from user cards to accept checks and dispense cash to authorized machine users. The machine can compare image data and magnetic data obtained from a check to determine the genuineness of the check. The machine can also determine whether a machine user is authorized to exchange a check for cash. A cash dispenser can be operated to dispense cash to a machine user in exchange for a deposited check. The machine dispenses the cash responsive to communications with a transaction host.
摘要翻译：一种自动银行业务器响应于从用户卡读取的数据来接受对被授权的机器用户的支票和现金的操作。该机器可以比较从支票获取的图像数据和磁数据，以确定支票的真实性。机器还可以确定机器用户是否有权交换支票以支付现金。可以使用自动取款机将现金分配给机器用户以换取存放支票。该机器响应于与交易主机的通信而分配现金。

8. 发明授权

US08128083B2 Cash dispensing automated banking machine and method 有权
标题翻译：现金分配自动银行机和方法
公开(公告)号：US08128083B2
公开(公告)日：2012-03-06
申请号：US11894192
申请日：2007-08-20
申请人： H. Thomas Graef , Kenneth C. Kontor , Michael Harty , Brian Jones
发明人： H. Thomas Graef , Kenneth C. Kontor , Michael Harty , Brian Jones
IPC分类号： B65H3/06 , B65H3/52
CPC分类号： B65H3/5207 , B65H3/06 , B65H3/0623 , B65H3/0638 , B65H3/0653 , B65H2301/423 , B65H2402/5441 , B65H2403/51 , B65H2404/17 , B65H2404/531 , B65H2404/5311 , B65H2404/5512 , B65H2511/135 , B65H2511/524 , B65H2515/34 , B65H2601/11 , B65H2601/123 , B65H2601/321 , B65H2601/324 , B65H2701/1912 , Y10T403/32852 , Y10T403/32991 , B65H2220/11
摘要： An automated banking machine (10) includes a sheet picking mechanism (210). The sheet picking mechanism includes a rotatable picking member (212). With each rotation an end sheet (266) can be picked from a stack (264) of sheets. The picking member (212) has an outer surface section that includes a high friction portion (256) axially adjacent to a low friction portion (258). The low friction portion comprises an arcuate projecting portion that reduces risk of damage to a leading edge area of the end sheet due to opposed picking and stripping forces.
摘要翻译：自动银行机（10）包括纸张拾取机构（210）。片材拾取机构包括可旋转拾取构件（212）。通过每次旋转，可以从片材的堆叠（264）拾取端片（266）。拾取构件（212）具有包括与低摩擦部分（258）轴向相邻的高摩擦部分（256）的外表面部分。低摩擦部分包括弧形突出部分，其减少由于相反的拾取和剥离力而损坏端片的前缘区域的风险。

9. 发明申请

US20100176190A1 Check accepting and cash dispensing automated banking machine system and method 有权
标题翻译：检查接收和现金分发自动银行机系统和方法
公开(公告)号：US20100176190A1
公开(公告)日：2010-07-15
申请号：US12661276
申请日：2010-03-12
申请人： Thomas A. VanKirk , Jon E. Washington , Brian Jones , William D. Beskitt , Harry Thomas Graef , David A. Peters , Damon J. Blackford , Dale H. Blackson , Edward L. Laskowski , Songtao Ma , Tim Crews , Wayne Warren , Martin J. Brown , Todd Galloway , Kenneth Turocy , Douglas T. Dominik , Jason J. Smolk , Brian E. Lucas , Bradley Lightner , James Meek , Robert W. Barnett , Mike Ryan , James R. Kay , Mark A. Ward , Victor Bell , William McCarthy , Matthew Pahl , Keith Carpenter , Laura Drozda
发明人： Thomas A. VanKirk , Jon E. Washington , Brian Jones , William D. Beskitt , Harry Thomas Graef , David A. Peters , Damon J. Blackford , Dale H. Blackson , Edward L. Laskowski , Songtao Ma , Tim Crews , Wayne Warren , Martin J. Brown , Todd Galloway , Kenneth Turocy , Douglas T. Dominik , Jason J. Smolk , Brian E. Lucas , Bradley Lightner , James Meek , Robert W. Barnett , Mike Ryan , James R. Kay , Mark A. Ward , Victor Bell , William McCarthy , Matthew Pahl , Keith Carpenter , Laura Drozda
IPC分类号： G07F19/00 , G06K5/00
CPC分类号： G07D11/0084 , G06Q20/042 , G06Q20/1085 , G07F19/20
摘要： An automated banking machine that operates responsive to data read from user cards which accepts checks and dispenses cash to users. The machine operates to acquire image and magnetic data from deposited checks to determine the genuineness of checks and the authority of a user to receive cash for such checks. Cash may be dispensed to the user in exchange for the deposited check. The machine dispenses cash responsive to communications with a transaction host.
摘要翻译：一种自动银行机器，其响应于从用户卡读取的数据进行操作，该数据接收检查并向用户分配现金。该机器用于从存放的检查中获取图像和磁性数据，以确定检查的真实性以及用户接受这种检查的现金的权限。可以将现金分配给用户以换取已存的支票。该机器响应于与交易主机的通信而分配现金。

10. 发明授权

US07739588B2 Leveraging markup language data for semantically labeling text strings and data and for providing actions based on semantically labeled text strings and data 有权
标题翻译：利用标记语言数据来语义标记文本字符串和数据，并根据语义标记的文本字符串和数据提供动作
公开(公告)号：US07739588B2
公开(公告)日：2010-06-15
申请号：US10608267
申请日：2003-06-27
申请人： Jeff Reynar , Brian Jones , Ziyi Wang
发明人： Jeff Reynar , Brian Jones , Ziyi Wang
IPC分类号： G06F15/00
CPC分类号： G06F17/218 , G06F17/2247 , G06F17/241
摘要： Markup language data applied to text or data is leveraged for providing helpful actions on certain types of text or data such as names, addresses, etc. Selected portions of text or data entered into a document and any associated markup language data are passed to an action dynamically linked library (DLL) for obtaining actions associated with markup language elements applied to the text or data. The text or data may be passed to a recognizer DLL for recognition of certain data types. The recognizer DLL utilizes markup language data associated with the text or data to assist recognition and labeling of text or data. After all applicable text and/or data is recognized and labeled, an action DLL is called for actions associated with the labeled text or data.
摘要翻译：应用于文本或数据的标记语言数据被用于为某些类型的文本或数据（例如姓名，地址等）提供有用的操作。输入到文档中的文本或数据的所选部分以及任何相关联的标记语言数据被传递到动作动态链接库（DLL），用于获取与应用于文本或数据的标记语言元素相关联的操作。文本或数据可以被传递到识别器DLL以识别某些数据类型。识别器DLL利用与文本或数据相关联的标记语言数据来辅助文本或数据的识别和标签。在所有适用的文本和/或数据被识别和标记之后，将调用与标记的文本或数据相关联的操作的动作DLL。

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