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1. 发明授权

US07022300B2 Process for producing inorganic spheres 失效
标题翻译：生产无机球体的方法
公开(公告)号：US07022300B2
公开(公告)日：2006-04-04
申请号：US10618656
申请日：2003-07-15
申请人： Toshiya Matsubara , Masaharu Tanaka , Shin Tatematsu , Kazuhiko Yamada , Kenji Yamada , Kenichi Ebata , Hajime Katayama , Kentarou Tsunozaki
发明人： Toshiya Matsubara , Masaharu Tanaka , Shin Tatematsu , Kazuhiko Yamada , Kenji Yamada , Kenichi Ebata , Hajime Katayama , Kentarou Tsunozaki
IPC分类号： C01B33/12
CPC分类号： C01B33/124 , B01F3/0811 , B01F5/0475 , B01J13/06
摘要： A process for producing inorganic spheres, which comprises injecting an aqueous liquid containing an inorganic compound through an inlet hole into an organic liquid which flows at a flow rate of from 0.001 to 2 m/s in a laminar flow state in a flow path to form a W/O type emulsion, and solidifying the aqueous liquid containing an inorganic compound in the W/O type emulsion.
摘要翻译：一种无机球体的制造方法，其特征在于，将含有无机化合物的含水液体通过入口孔注入到以流路为流量的0.001〜2m / s的有机液体中，形成流路 W / O型乳液，并且在W / O型乳液中固化含有无机化合物的含水液体。

2. 发明申请

US20080267853A1 PROCESS FOR PRODUCING INORGANIC SPHERES 审中-公开
标题翻译：生产无机球体的方法
公开(公告)号：US20080267853A1
公开(公告)日：2008-10-30
申请号：US12146563
申请日：2008-06-26
申请人： Toshiya Matsubara , Masaharu Tanaka , Hajime Katayama , Kenji Yamada
发明人： Toshiya Matsubara , Masaharu Tanaka , Hajime Katayama , Kenji Yamada
IPC分类号： C01B33/32
CPC分类号： B01J13/02 , B01F3/0811 , B01F5/0475 , B01J2/06 , B01J13/04 , C01B33/193
摘要： To provide a process for producing inorganic spheres having a substantially uniform particle size with high productivity. In a process for producing inorganic spheres, which comprises a step of injecting an alkaline aqueous liquid containing an inorganic compound into a laminar flow of an organic liquid containing a surfactant through micropores to form a W/O type emulsion, and a step of solidifying droplets of the aqueous liquid containing an inorganic compound in the W/O type emulsion by an acid to form inorganic spheres, as the organic liquid, one which is brought into contact with an acid in a state of the W/O type emulsion or after separated from the W/O type emulsion, or one which is brought into contact with the aqueous liquid and then separated and recovered, is used.
摘要翻译：提供具有高生产率的具有基本上均匀粒径的无机球的方法。在制备无机球体的方法中，其包括将含有无机化合物的碱性含水液体通过微孔注入到含有表面活性剂的有机液体的层流中以形成W / O型乳液的步骤，以及固化液滴的步骤的W / O型乳液中含有无机化合物的水性液体，形成无机球，作为有机液体，与W / O型乳液状态下的酸接触或分离后使用W / O型乳液，或与水性液体接触然后分离回收的乳液。

3. 发明授权

US07442356B2 Process for producing inorganic spheres 失效
标题翻译：生产无机球体的方法
公开(公告)号：US07442356B2
公开(公告)日：2008-10-28
申请号：US11271905
申请日：2005-11-14
申请人： Toshiya Matsubara , Masaharu Tanaka , Hajime Katayama , Kenji Yamada
发明人： Toshiya Matsubara , Masaharu Tanaka , Hajime Katayama , Kenji Yamada
IPC分类号： C01B33/32 , C01B33/12 , C01F1/00 , C01F3/00 , C01F7/00 , C01G15/00 , C22B21/00 , C22B35/00 , C22B58/00 , C22B61/00 , B01F3/04 , B01F17/00 , C09K3/00
CPC分类号： B01J13/02 , B01F3/0811 , B01F5/0475 , B01J2/06 , B01J13/04 , C01B33/193
摘要： To provide a process for producing inorganic spheres having a substantially uniform particle size with high productivity. In a process for producing inorganic spheres, which comprises a step of injecting an alkaline aqueous liquid containing an inorganic compound into a laminar flow of an organic liquid containing a surfactant through micropores to form a W/O type emulsion, and a step of solidifying droplets of the aqueous liquid containing an inorganic compound in the W/O type emulsion by an acid to form inorganic spheres, as the organic liquid, one which is brought into contact with an acid in a state of the W/O type emulsion or after separated from the W/O type emulsion, or one which is brought into contact with the aqueous liquid and then separated and recovered, is used.
摘要翻译：提供具有高生产率的具有基本上均匀粒径的无机球的方法。在制备无机球体的方法中，其包括将含有无机化合物的碱性含水液体通过微孔注入到含有表面活性剂的有机液体的层流中以形成W / O型乳液的步骤，以及固化液滴的步骤的W / O型乳液中含有无机化合物的水性液体，形成无机球，作为有机液体，与W / O型乳液状态下的酸接触或分离后使用W / O型乳液，或与水性液体接触然后分离回收的乳液。

4. 发明申请

US20060067864A1 Process for producing inorganic spheres 失效
标题翻译：生产无机球体的方法
公开(公告)号：US20060067864A1
公开(公告)日：2006-03-30
申请号：US11271905
申请日：2005-11-14
申请人： Toshiya Matsubara , Masaharu Tanaka , Hajime Katayama , Kenji Yamada
发明人： Toshiya Matsubara , Masaharu Tanaka , Hajime Katayama , Kenji Yamada
IPC分类号： C01F7/00 , C01B33/00 , B01F3/08 , B01F3/12
CPC分类号： B01J13/02 , B01F3/0811 , B01F5/0475 , B01J2/06 , B01J13/04 , C01B33/193
摘要： To provide a process for producing inorganic spheres having a substantially uniform particle size with high productivity. In a process for producing inorganic spheres, which comprises a step of injecting an alkaline aqueous liquid containing an inorganic compound into a laminar flow of an organic liquid containing a surfactant through micropores to form a W/O type emulsion, and a step of solidifying droplets of the aqueous liquid containing an inorganic compound in the W/O type emulsion by an acid to form inorganic spheres, as the organic liquid, one which is brought into contact with an acid in a state of the W/O type emulsion or after separated from the W/O type emulsion, or one which is brought into contact with the aqueous liquid and then separated and recovered, is used.
摘要翻译：提供具有高生产率的具有基本上均匀粒径的无机球的方法。在制备无机球体的方法中，其包括将含有无机化合物的碱性含水液体通过微孔注入到含有表面活性剂的有机液体的层流中以形成W / O型乳液的步骤，以及固化液滴的步骤的W / O型乳液中含有无机化合物的水性液体，形成无机球，作为有机液体，与W / O型乳液状态下的酸接触或分离后使用W / O型乳液，或与水性液体接触然后分离回收的乳液。

5. 发明授权

US07537746B2 Process and apparatus for producing inorganic spheres 有权
标题翻译：用于生产无机球体的方法和装置
公开(公告)号：US07537746B2
公开(公告)日：2009-05-26
申请号：US10864593
申请日：2004-06-10
申请人： Toshiya Matsubara , Masaharu Tanaka , Kenji Yamada , Hajime Katayama
发明人： Toshiya Matsubara , Masaharu Tanaka , Kenji Yamada , Hajime Katayama
IPC分类号： C01B33/12 , B01J35/08 , B29B9/00 , B22D11/01 , B22F9/00 , B28B17/00 , B29C67/02
CPC分类号： B01J2/08 , B01F3/0807 , B01F5/0475 , B01F13/0059 , B01F2215/0431 , B01F2215/045 , B01J13/046
摘要： A process for producing inorganic spheres, which comprises injecting an aqueous liquid containing an inorganic compound into a laminar flow of an organic liquid which runs at a flow rate of from 0.001 to 2 m/s in a flow path compartmentalized by a partition wall through a plurality of inlet holes formed in one partition wall to form a W/O type emulsion containing the organic liquid as a dispersion medium and the aqueous liquid containing the inorganic compound as a dispersed phase, and solidifying the aqueous liquid containing an inorganic compound in the W/O type emulsion, wherein the partition wall having a plurality of inlet holes is made of a metal sheet having a surface subjected to water repellent treatment.
摘要翻译：一种无机球体的制造方法，其特征在于，将含有无机化合物的水性液体注入到通过分隔壁分隔的流路中以0.001〜2m / s的流量流过的有机液体的层流多个入口孔形成在一个分隔壁中，以形成含有有机液体作为分散介质的W / O型乳液和含有无机化合物作为分散相的含水液体，并将含有无机化合物的水性液体固化在W / O型乳液，其中具有多个入口孔的分隔壁由具有防水处理表面的金属片制成。

6. 发明申请

US20060034788A1 Skin cosmetic 审中-公开
标题翻译：皮肤化妆品
公开(公告)号：US20060034788A1
公开(公告)日：2006-02-16
申请号：US11196521
申请日：2005-08-04
申请人： Masaakira Horino , Toshiya Matsubara , Masaharu Tanaka , Taizo Miyoshi , Masaki Inoue
发明人： Masaakira Horino , Toshiya Matsubara , Masaharu Tanaka , Taizo Miyoshi , Masaki Inoue
IPC分类号： A61K8/25
CPC分类号： A61Q1/02 , A61K8/25 , A61K2800/412 , A61Q1/12 , A61Q19/08
摘要： There is provided a cosmetic, particularly a skin cosmetic, excellent in imparting transparency (transparent feeling) to the skin, conditioning the skin texture and making wrinkles and hair follicles imperceptible when applied. The cosmetic comprises a powder of porous spherical silica having an average particle size (based on volume) from 3.0 to 20 μm, a maximum particle size of 50 μm or smaller, and a pore volume from 1.5 to 3.0 cm3/g, wherein the powder is characterized in that the minimum value of dlog (storage elasticity)/dlog (shear stress) is −10 or more, when 40 g of squalane is added to 15 cm3 of apparent volume of said powder of porous spherical silica, the resulting paste is charged in thickness of 2 mm between parallel plates of 2.5 cm diameter, one of the plates is subjected to an angular vibration to another in a frequency of 2 Hz, dynamic viscoelasticity is measured by increasing an average shear stress between the plates from 10 Pa to 10 kPa and correlation between log (shear stress) versus log (storage elasticity) is measured.
摘要翻译：提供了赋予皮肤透明度（透明感）优异的化妆品，特别是皮肤化妆品，其在使用时不易察觉，调理皮肤纹理并使皱纹和毛囊变得不可察觉。化妆品包括平均粒度（基于体积）为3.0〜20μm，最大粒径为50μm以下，孔体积为1.5〜3.0cm 3的多孔性球状二氧化硅粉末， SUP> / g，其中粉末的特征在于当将40g角鲨烷加入15cm 3 / sup时，dlog（储存弹性）/ dlog（剪切应力）的最小值为-10或更大所述多孔球形二氧化硅粉末的表观体积，将所得糊料以2.5cm直径的平行板之间的厚度为2mm填充，其中一块板以2Hz的频率进行另一个振动，动态通过将板之间的平均剪切应力从10Pa增加到10kPa来测量粘弹性，并测量log（剪切应力）对log（存储弹性）之间的相关性。

7. 发明授权

US6048470A Alumina sol, alumina hydrate powder and processes for their production 失效
公开(公告)号：US6048470A
公开(公告)日：2000-04-11
申请号：US992906
申请日：1997-12-18
申请人： Katsumasa Nakahara , Kenji Yamada , Hachiro Hirano , Toshiya Matsubara
发明人： Katsumasa Nakahara , Kenji Yamada , Hachiro Hirano , Toshiya Matsubara
IPC分类号： C01F7/02 , B32B5/16
CPC分类号： B82Y30/00 , C01F7/02 , C01F7/025 , C01P2002/60 , C01P2004/62 , C01P2004/64 , C01P2006/12 , C01P2006/14 , C01P2006/16 , C01P2006/60 , Y10T428/256 , Y10T428/257 , Y10T428/2982 , Y10T428/2991
摘要： A process for producing an alumina sol, which comprises stirring a dispersion of an alumina hydrate having a solid content of from 1 to 40 wt % at a pH of from 7 to 12 with an effective consumptive power of at least 0.5 kW/m.sup.3 for aggregation treatment, and then adding an acid thereto for peptization treatment.

8. 发明授权

US06342293B1 Alumina sol, alumina hydrate powder and processes for their production 有权
标题翻译：氧化铝溶胶，氧化铝水合物粉末及其生产工艺
公开(公告)号：US06342293B1
公开(公告)日：2002-01-29
申请号：US09489941
申请日：2000-01-24
申请人： Katsumasa Nakahara , Kenji Yamada , Hachiro Hirano , Toshiya Matsubara
发明人： Katsumasa Nakahara , Kenji Yamada , Hachiro Hirano , Toshiya Matsubara
IPC分类号： B32B516
CPC分类号： B82Y30/00 , C01F7/02 , C01F7/025 , C01P2002/60 , C01P2004/62 , C01P2004/64 , C01P2006/12 , C01P2006/14 , C01P2006/16 , C01P2006/60 , Y10T428/249979 , Y10T428/256 , Y10T428/257 , Y10T428/2982 , Y10T428/2991
摘要： A process for producing an alumina sol, which comprises stirring a dispersion of an alumina hydrate having a solid content of from 1 to 40 wt % at a pH of from 7 to 12 with an effective consumptive power of at least 0.5 kW/m3 for aggregation treatment, and then adding an acid thereto for peptization treatment.
摘要翻译：一种氧化铝溶胶的制造方法，其特征在于，将pH7〜12的固体成分浓度为1〜40重量％的水合氧化铝的分散液搅拌至少为0.5kW / m 3以上的有效消耗功率处理，然后加入酸进行胶溶处理。

9. 发明申请

US20130210039A1 BLOOD INSULIN RESISTANCE AND DIABETES MARKER PROGRANULIN, METHOD FOR ANALYZING CONCENTRATION OF PROGRANULIN IN BLOOD SAMPLE, AND METHOD FOR SCREENING FOR SUBSTANCE THAT IMPROVES INSULIN RESISTANCE AND IMPROVES OR SUPPRESSES DIABETES 审中-公开
标题翻译：血清抗胰蛋白酶抗性和糖尿病标记物，用于分析血清样品浓度的方法，以及用于筛选改善胰岛素抵抗和改善或抑制糖尿病的物质的方法
公开(公告)号：US20130210039A1
公开(公告)日：2013-08-15
申请号：US13819704
申请日：2011-07-13
申请人： Toshiya Matsubara , Makoto Watanabe , Susumu Seino , Kohtaro Minami , Osamu Nishimura , Ayako Mita
发明人： Toshiya Matsubara , Makoto Watanabe , Susumu Seino , Kohtaro Minami , Osamu Nishimura , Ayako Mita
IPC分类号： G01N33/68
CPC分类号： G01N33/6893 , G01N2333/475 , G01N2500/00 , G01N2500/10 , G01N2800/042
摘要： The present invention provides a marker capable of detecting insulin resistance and diabetes in a collected blood sample, a method for analyzing said marker, a method for screening a substance improving insulin resistance, and improving or suppressing diabetes. A blood insulin resistance marker and a blood diabetes marker, which comprises a polypeptide comprising at least 15 continuous amino acids in an amino acid sequence constituting progranulin. A method for analyzing a blood marker, which comprises the steps of: measuring a concentration of an insulin resistance marker or a diabetes marker in a collected blood sample; and comparing the measured concentration with a normal blood concentration of the marker. A method for screening a substance improving insulin resistance, and improving or suppressing diabetes, which comprises the steps of: administering a candidate substance to a living body expressing insulin resistance or suffering from diabetes; measuring a blood concentration of a marker in the living body after administration; and comparing the measured concentration of the marker with a blood concentration of the marker not administered with the candidate substance.
摘要翻译：本发明提供能够检测收集的血液样品中的胰岛素抵抗和糖尿病的标记物，分析所述标记物的方法，用于筛选改善胰岛素抵抗的物质的方法，以及改善或抑制糖尿病。一种血液胰岛素抵抗标记物和血液糖尿病标志物，其包含在构成颗粒体蛋白前体的氨基酸序列中包含至少15个连续氨基酸的多肽。一种分析血液标记物的方法，包括以下步骤：测量所收集的血液样品中胰岛素抵抗标志物或糖尿病标志物的浓度; 并将测量的浓度与标记物的正常血液浓度进行比较。一种筛选改善胰岛素抵抗的物质，改善或抑制糖尿病的方法，包括以下步骤：将候选物质施用于表达胰岛素抵抗或患有糖尿病的活体; 测定给药后的生物体中的标记物的血液浓度; 并将标记物的测定浓度与未施用候选物质的标记物的血液浓度进行比较。

10. 发明授权

US4734821A Electrolytic capacitor 失效
标题翻译：电解电容器
公开(公告)号：US4734821A
公开(公告)日：1988-03-29
申请号：US49297
申请日：1987-05-13
申请人： Takeshi Morimoto , Yoshiki Hamatani , Toshiya Matsubara , Naoto Iwano , Hideo Shimizu
发明人： Takeshi Morimoto , Yoshiki Hamatani , Toshiya Matsubara , Naoto Iwano , Hideo Shimizu
IPC分类号： H01G9/02 , H01G9/022 , H01G9/00
CPC分类号： H01G9/022
摘要： An electrolytic capacitor comprising a capacitor element and an electrolyte impregnated to the element, wherein the electrolyte comprises an organic polar solvent and a solute dissolved in the solvent, said solute being selected from the group consisting of a quaternary ammonium salt of an aromatic carboxylic acid, a quaternary ammonium salt of cycloalkene carboxylic acid and a quaternary ammonium salt of an unsaturated aliphatic carboxylic acid.
摘要翻译：一种电解电容器，包括电容器元件和浸渍到元件中的电解质，其中所述电解质包含有机极性溶剂和溶解在溶剂中的溶质，所述溶质选自芳族羧酸的季铵盐，环烯烃羧酸的季铵盐和不饱和脂族羧酸的季铵盐。

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