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    • 1. 发明申请
    • ENDOSCOPE APPARATUS
    • 内窥镜装置
    • US20100053312A1
    • 2010-03-04
    • US12516074
    • 2007-11-22
    • Toshiaki WatanabeRyo Karasawa
    • Toshiaki WatanabeRyo Karasawa
    • H04N7/18
    • A61B1/041A61B1/00096A61B1/00165A61B1/00181A61B1/043A61B1/0638A61B1/07
    • The distal end of an inserted portion, having a simple structure, is reduced in diameter, loss of light incident from a body cavity is reduced, and light from two different directions is observed simultaneously and in a separated fashion. Provided is an endoscope apparatus (1) including an inserted portion (2) to be inserted inside a body cavity; a first dichroic mirror (8), disposed in a distal end portion of the inserted portion (2), that transmits light (L4) in a first wavelength band, which is incident from a longitudinal axial direction and that deflects light (L2) in a second wavelength band, which is incident from a radial direction, in the longitudinal axial direction, thereby multiplexing it with the light (L4) in the first wavelength band; a second dichroic mirror (13) that splits the light (L2, L4) multiplexed by the first dichroic mirror (8) into each wavelength band; and two image-acquisition units (16, 17) that respectively acquire the light (L2, L4) in the first and second wavelength bands split by the second dichroic mirror (13).
    • 具有简单结构的插入部分的远端的直径减小,从体腔入射的光的损失减少,并且同时并以分离的方式观察来自两个不同方向的光。 提供一种内窥镜装置(1),其具有插入体腔内的插入部(2) 设置在所述插入部分(2)的远端部分中的第一分色镜(8),其透射从纵向轴向入射的第一波长带中的光(L4),并使光(L2)偏转 从纵向轴向从径向入射的第二波长带,由此将其与第一波长带中的光(L4)进行多路复用; 将由所述第一分色镜(8)复用的光(L2,L4)分割成各波长带的第二分色镜(13) 以及分别获取由第二分色镜(13)分割的第一和第二波长带中的光(L2,L4)的两个图像获取单元(16,17)。
    • 2. 发明申请
    • FLUORESCENCE ENDOSCOPE APPARATUS
    • 荧光内窥镜装置
    • US20100036262A1
    • 2010-02-11
    • US12531999
    • 2008-03-14
    • Toshiaki WatanabeRyo Karasawa
    • Toshiaki WatanabeRyo Karasawa
    • A61B1/07A61B6/00
    • H04N5/2256A61B1/00009A61B1/043A61B1/0638A61B1/0646A61B5/0071A61B5/0084H04N2005/2255
    • The effect of noise light originating in a light guide portion is removed by simple calculations, and a clear fluorescence image that facilitates distinction between lesion tissue and normal tissue is acquired. Provided is a fluorescence endoscope apparatus including an insertion portion inserted into a body cavity; a light source unit that is disposed at a base end of the insertion portion and that emits excitation light and reference light that contains at least a part of the wavelength band of fluorescence produced by the excitation light; a light guide portion that guides the excitation light and the reference light emitted from the light source unit to a distal end of the insertion portion; an irradiation control unit that switches between a first irradiation state in which the excitation light guided by the light guide portion is radiated onto an inner wall of the body cavity and a second irradiation state in which the reference light is radiated onto the inner wall of the body cavity; an image-acquisition unit that acquires reflected light of the reference light and the fluorescence returning from the inner wall of the body cavity to the insertion portion; and an image computing unit that generates a fluorescence image signal by calculating the difference between a first image-acquisition signal acquired by the image-acquisition unit in the first irradiation state and a second image-acquisition signal acquired in the second irradiation state.
    • 通过简单的计算来消除起源于导光部分的噪声光的影响,并且获得有助于区分病变组织和正常组织的透明荧光图像。 本发明提供一种荧光内窥镜装置,其具有插入体腔内的插入部, 光源单元,其设置在所述插入部的基端,并且发射激发光和包含由所述激发光产生的荧光的至少一部分波长带的参考光; 导光部,其将从光源单元发射的激发光和参照光引导到插入部的前端; 照射控制单元,其在由所述导光部分引导的激发光照射到所述体腔内壁上的第一照射状态和所述参照光照射到所述体腔的内壁上的第二照射状态之间切换 体腔; 图像获取单元,其获取参考光的反射光和从体腔的内壁返回到插入部的荧光; 以及图像计算单元,其通过计算由第一照射状态下的图像获取单元获取的第一图像获取信号与在第二照射状态中获取的第二图像采集信号之间的差异来生成荧光图像信号。
    • 3. 发明授权
    • Endoscope apparatus
    • 内窥镜装置
    • US08773521B2
    • 2014-07-08
    • US12516074
    • 2007-11-22
    • Toshiaki WatanabeRyo Karasawa
    • Toshiaki WatanabeRyo Karasawa
    • A62B1/04
    • A61B1/041A61B1/00096A61B1/00165A61B1/00181A61B1/043A61B1/0638A61B1/07
    • The distal end of an inserted portion, having a simple structure, is reduced in diameter, loss of light incident from a body cavity is reduced, and light from two different directions is observed simultaneously and in a separated fashion. Provided is an endoscope apparatus (1) including an inserted portion (2) to be inserted inside a body cavity; a first dichroic mirror (8), disposed in a distal end portion of the inserted portion (2), that transmits light (L4) in a first wavelength band, which is incident from a longitudinal axial direction and that deflects light (L2) in a second wavelength band, which is incident from a radial direction, in the longitudinal axial direction, thereby multiplexing it with the light (L4) in the first wavelength band; a second dichroic mirror (13) that splits the light (L2, L4) multiplexed by the first dichroic mirror (8) into each wavelength band; and two image-acquisition units (16, 17) that respectively acquire the light (L2, L4) in the first and second wavelength bands split by the second dichroic mirror (13).
    • 具有简单结构的插入部分的远端的直径减小,从体腔入射的光的损失减少,并且同时并以分离的方式观察来自两个不同方向的光。 提供一种内窥镜装置(1),其具有插入体腔内的插入部(2) 设置在所述插入部分(2)的远端部分中的第一分色镜(8),其透射从纵向轴向入射的第一波长带中的光(L4),并使光(L2)偏转 从纵向轴向从径向入射的第二波长带,由此将其与第一波长带中的光(L4)进行多路复用; 将由所述第一分色镜(8)复用的光(L2,L4)分割成各波长带的第二分色镜(13) 以及分别获取由第二分色镜(13)分割的第一和第二波长带中的光(L2,L4)的两个图像获取单元(16,17)。
    • 4. 发明申请
    • FLUORESCENCE ENDOSCOPE
    • 荧光内窥镜
    • US20100020163A1
    • 2010-01-28
    • US12518377
    • 2007-12-07
    • Toshiaki WatanabeAtsushi OkawaYasushige IshiharaRyo Karasawa
    • Toshiaki WatanabeAtsushi OkawaYasushige IshiharaRyo Karasawa
    • H04N7/18
    • A61B5/0071A61B1/00165A61B1/043A61B5/0084A61B2560/0223
    • A fluorescence endoscope is provided that can easily judge whether body-cavity tissue is benign or malignant when fluorescence generated at the entire inner circumferential face of the body cavity serving as a subject is observed. The fluorescence endoscope includes: an insertion portion (5) be inserted into a body cavity (3); a balloon (15) brought into contact with an inner wall of the body cavity (3) located in radial directions of the insertion portion (5), thereby positioning the insertion portion (5) with respect to the body cavity (3) in the radial directions of the insertion portion (5); a light emitting and introducing unit (17, 19) emits excitation light for irradiating the inner wall, outward in the radial directions of the insertion portion (5), and introduces fluorescence generated at the inner wall to the inside of the insertion portion (5) from a plurality of different radial directions of the insertion portion (5); an image-acquisition unit (21) acquires an image with the fluorescence introduced by the light emitting and introducing unit (17, 19); a correction-signal calculating unit (57) calculates a correction signal for correcting an image-acquisition signal output from the image-acquisition unit (21), based on a distance between the insertion portion (5) and a contact surface of the balloon (15) that is brought into contact with the inner wall; and a signal processing unit (57) corrects the intensity of the image-acquisition signal based on the correction signal and generates an image signal from the corrected image-acquisition signal.
    • 提供了一种荧光内窥镜,其可以容易地判断当观察到在用作对象的体腔的整个内周面处产生的荧光时,体腔组织是良性还是恶性。 荧光内窥镜包括:插入部(5)插入体腔(3)中; 与所述体腔(3)的位于所述插入部(5)的径向方向的内壁接触的气囊(15),从而将所述插入部(5)相对于所述体腔(3)定位在所述插入部 插入部分(5)的径向方向; 发光引入单元(17,19)发射用于照射插入部(5)的径向外侧的内壁的激发光,并且将在内壁产生的荧光引入到插入部(5)的内部 )从所述插入部(5)的多个不同的径向方向移动; 图像获取单元(21)获取由发光和导入单元(17,19)引入的荧光的图像。 校正信号计算单元(57)基于插入部分(5)和气球的接触表面之间的距离来计算用于校正从图像获取单元(21)输出的图像采集信号的校正信号 15)与内壁接触; 并且信号处理单元(57)基于校正信号校正图像采集信号的强度,并从校正后的图像采集信号生成图像信号。
    • 8. 发明授权
    • In-vivo information acquisition apparatus and in-vivo information acquisition apparatus system
    • 体内信息获取装置和体内信息采集装置系统
    • US08195276B2
    • 2012-06-05
    • US10564303
    • 2005-03-24
    • Akio UchiyamaHironobu TakizawaRyo Karasawa
    • Akio UchiyamaHironobu TakizawaRyo Karasawa
    • A61B5/05
    • A61B1/041A61B1/00016A61B1/273A61B1/31A61B5/0031A61B5/062A61B5/073A61B5/14503A61B5/14539A61B5/14546A61B5/6884
    • There is provided an in-vivo information acquisition apparatus capable of detecting high-accuracy in-vivo information substantially at the same time in a plurality of different examination sites in a body cavity and an in-vivo information acquisition apparatus system capable of introducing a plurality of in-vivo information acquisition apparatuses into a patient at the same time. The in-vivo information acquisition apparatus includes a specimen-collecting section for collecting a specimen at an examination site in a body cavity, a specimen-evaluating section for evaluating the specimen collected by the specimen-collecting section and outputting an evaluation result, a labeling section having identification information unique to the in-vivo information acquisition apparatus, a communication section for receiving a signal transmitted from the outside and for transmitting to the outside the evaluation result output by the specimen-evaluating section, and a power supply section for supplying electrical power.
    • 提供了一种体内信息获取装置,其能够在体腔中的多个不同的检查部位和能够引入多个体内的体内信息获取装置系统中基本上同时检测高精度的体内信息 的体内信息获取装置同时进入患者。 体内信息获取装置包括:体腔内的检查部位收集标本的检体收集部;评价收集部收集的标本的评价部,输出评价结果;标签 具有针对体内信息获取装置特有的识别信息的部分,通信部,其接收从外部发送的信号,并向外部发送由检体评价部输出的评价结果​​;以及电源部, 功率。