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    • 1. 发明授权
    • Phase difference controller and method for controlling phase difference
    • 相位差控制器和控制相位差的方法
    • US5298973A
    • 1994-03-29
    • US909378
    • 1992-07-06
    • Tomoyuki FukazawaMitsuru SanoNobuyuki Sakayanagi
    • Tomoyuki FukazawaMitsuru SanoNobuyuki Sakayanagi
    • G01J4/04G02B26/06G01J4/00G02F1/01
    • G02B26/06
    • Phas difference controller for use in equipments having a photoelastic modulator, such as ellipsometers and optical rotatory dispersion meters. For enabling the photoelastic modulator to produce the constant amplitude of the phase difference regardless of the change in the wavelength of light incident into the photoelastic modulator, and regardless of the change in the temperature of the photoelastic modulator itself or its atmosphere, the controller has a birefringence polarizer which splits incident light into two linearly polarized light beams, ordinary light and extraordinary light. One of them acts as reference light LR and the other one acts as main light LM. These light beams pass through a photoelastic modulator which is forced to vibrate at angular frequency of .omega.. After that, the passed reference light LR is detected by a photomultiplier via an analyzer. The photoelastic modulator is forced to vibrate at angular frequency of .omega. so that the ratio of the amplitude of the ac component of angular frequency of 2.omega. to the dc component included in the output signal of the photomultiplier is maintained constant.
    • Phas差分控制器,用于具有光弹性调制器的设备,如椭偏仪和旋光分散仪。 为了使光弹性调制器能够产生相位差的恒定幅度,而与入射到光弹性调制器中的光的波长无关,并且无论光弹性调制器本身或其大气的温度如何变化,控制器具有 双折射偏振器将入射光分为两个线性偏振光束,普通光和非凡光。 其中一个作为参考光LR,另一个用作主光LM。 这些光束通过被迫以(ω)的角频率振动的光弹性调制器。 之后,通过光电倍增管经由分析器检测通过的基准光LR。 光弹性调制器被强制以(ω)的角频率振动,使得角频率为2(ω)的交流分量的振幅与包含在光电倍增器的输出信号中的直流分量的比率保持恒定。
    • 3. 发明授权
    • Highly sensitive detection method of amino acid derivative
    • 氨基酸衍生物的高灵敏度检测方法
    • US5538896A
    • 1996-07-23
    • US211339
    • 1994-05-09
    • Akira TsugitaMasaharu KamoMitsuru Sano
    • Akira TsugitaMasaharu KamoMitsuru Sano
    • G01N33/68G01N33/00
    • G01N33/6824
    • To easily detect an amino acid derivative with high sensitivity in carrying out amino acid sequence analysis of a protein from an amino terminal, 2-anilino-5-thiazolinone amino acid derivative is reacted with a volatile primary amine represented by the general formula X-NH.sub.2, wherein X denotes a hydrocarbon containing a halogen to form a phenylthiocarbamyl amino acid derivative, and the phenylthiocarbamyl amino acid derivative is detected by using a gas chromatograph provided with an ECD. Accordingly, amino acid sequencing may be performed with high sensitivity without the need to use harmful radioisotope labeled or fluorescent amino compounds.
    • PCT No.PCT / JP93 / 00744 Sec。 371日期1994年5月9日 102(e)日期1994年5月9日PCT提交1993年6月2日PCT公布。 公开号WO94 / 02854 日期1994年2月3日为了容易地从氨基末端进行氨基酸序列分析蛋白质的高灵敏度检测氨基酸衍生物,将2-苯胺基-5-噻唑啉酮氨基酸衍生物与由 通式X-NH 2,其中X表示含有卤素以形成苯基硫代氨基甲酰基氨基酸衍生物的烃,苯基硫代氨基甲酰基氨基酸衍生物通过使用具有ECD的气相色谱仪进行检测。 因此,可以高灵敏度地进行氨基酸测序,而不需要使用有害的放射性同位素标记或荧光氨基化合物。