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1. 发明授权

US06242430B1 Cyclodextrin-based rotaxane dyes, labeling agent using the dye, and a method for labeling 失效
标题翻译：基于环糊精的轮烷染料，使用染料的标记试剂和标记方法
公开(公告)号：US06242430B1
公开(公告)日：2001-06-05
申请号：US09301635
申请日：1999-04-29
申请人： Tomomi Suzuki , Hitoshi Nohta , Shigetoshi Okazaki
发明人： Tomomi Suzuki , Hitoshi Nohta , Shigetoshi Okazaki
IPC分类号： A61K3120
CPC分类号： B82Y5/00 , A61K47/6951 , C09B57/00
摘要： This invention provides rotaxane type dyes. Specifically, the rotaxane type dye according to the invention has a rotaxane structure which binds dye molecules to both of the termini of a chain group penetrating a cyclodextrin ring, which possesses excellent water-solubility, and which is capable of having a plurality of different dyes.
摘要翻译：本发明提供了轮烷型染料。具体地说，根据本发明的轮烷型染料具有将染料分子结合到贯穿环糊精环的链基团的两末端的轮烷结构，其具有优异的水溶性，并且能够具有多种不同的染料。

2. 发明申请

US20060039520A1 Target for generating deuteron and target apparatus for generating deuteron comprising the same 审中-公开
标题翻译：用于产生氘核的目标和用于产生包含该氘核的氘核的目标装置
公开(公告)号：US20060039520A1
公开(公告)日：2006-02-23
申请号：US10533453
申请日：2003-12-16
申请人： Hironori Takahashi , Shigetoshi Okazaki , Shinji Ohsuka
发明人： Hironori Takahashi , Shigetoshi Okazaki , Shinji Ohsuka
IPC分类号： H05H6/00 , G21B1/00
CPC分类号： H05H6/00 , H05H3/02
摘要： The present invention relates to a deuteron generating target having a construction for generating deuteron efficiently, and a deuteron generating target apparatus including the same. The deuteron generating target is constructed by providing an upper film mainly composed of a deuterated organic compound onto a base film mainly composed of a halogen-containing organic compound.
摘要翻译：本发明涉及具有用于有效地产生氘核的结构的氘核产生靶，以及含有该氘核产生靶的装置。氘核产生靶是通过将主要由氘代有机化合物组成的上部膜提供到主要由含卤素的有机化合物组成的基底膜上构成的。

3. 发明授权

US5905030A Method and apparatus for assaying enzymatic reaction 失效
标题翻译：用于测定酶反应的方法和装置
公开(公告)号：US5905030A
公开(公告)日：1999-05-18
申请号：US77928
申请日：1998-06-05
申请人： Shigetoshi Okazaki , Hiroyuki Matsumoto
发明人： Shigetoshi Okazaki , Hiroyuki Matsumoto
IPC分类号： G01N21/552 , C12Q1/34 , C12Q1/00
CPC分类号： G01N21/552
摘要： A method and apparatus for measuring enzyme activity by supplying a substrate solution and an enzyme solution into a reaction vessel combined with a total reflection absorption prism is disclosed. A measurement solution (40) in which the enzyme solution and the substrate solution are combined together is kept at a constant temperature within the reaction vessel (26) by a temperature control unit (23), and is stirred by a stirrer (21). Infrared light (36) emitted from an infrared light source (3) is made incident on the interface between a total reflection absorption prism (28) disposed in contact with the measurement solution (40) and the measurement solution (40) from the side of the total reflection absorption prism (28) and is totally reflected by the interface. The spectrum of transmitted infrared light (37) thus totally reflected and emitted is detected by an infrared light detector (5). According to thus detected spectrum, a change in the infrared absorption spectrum or absorbance is determined, whereby the enzyme reaction in the measurement solution (40) is measured.
摘要翻译： PCT No.PCT / JP97 / 00513 Sec。 371日期：1998年6月5日 102（e）1998年6月5日PCT 1997年2月24日提交PCT公布。出版物WO97 / 32198 日期1997年8月4日公开了一种通过将底物溶液和酶溶液供给到与全反射吸收棱镜结合的反应容器中来测量酶活性的方法和装置。将酶溶液和底物溶液组合在一起的测量溶液（40）通过温度控制单元（23）在反应容器（26）内保持恒定温度，并通过搅拌器（21）搅拌。从红外光源（3）发射的红外光（36）入射到与测量溶液（40）接触设置的全反射吸收棱镜（28）和测量溶液（40）之间的界面上，全反射吸收棱镜（28），并被界面全反射。由红外光检测器（5）检测由此全反射和发射的透射红外光（37）的光谱。根据如此检测的光谱，测定红外吸收光谱或吸光度的变化，由此测量测量溶液（40）中的酶反应。

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