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1. 发明申请

US20110223626A1 METHOD FOR QUANTITATIVELY DETERMINING CHOLESTEROL IN LOW-DENSITY LIPOPROTEINS,REAGENT FOR QUANTITATIVE DETERMINATION,AND QUANTITATIVE DETERMINATION KIT 有权
标题翻译：低密度脂蛋白中定量测定胆固醇的方法，定量测定用试剂和定量测定试剂盒
公开(公告)号：US20110223626A1
公开(公告)日：2011-09-15
申请号：US13128444
申请日：2009-11-13
申请人： Tomomi Murakami , Tomoko Aratake , Shingo Mishima , Hideyuki Kuwata
发明人： Tomomi Murakami , Tomoko Aratake , Shingo Mishima , Hideyuki Kuwata
IPC分类号： C12Q1/60
CPC分类号： C12Q1/60 , C12Q1/26 , C12Q1/44 , G01N33/92 , G01N2800/044 , G01N2800/323
摘要： A method for measuring cholesterol in low-density lipoprotein contained in a sample, which comprises reacting a sample with (i) a combination of cholesterol ester hydrolase and cholesterol oxidase or (ii) a combination of cholesterol ester hydrolase, an oxidized coenzyme and cholesterol dehydrogenase in the presence of: [a] a polyoxyethylene-polyoxyalkylene alkylaryl ether; [b] one or more surfactants selected from the group consisting of a polyoxyethylene-polyoxyalkylene copolymer, a polyoxyethylene alkenyl ether, a polyoxyethylene branched alkyl ether, and a polyoxyethylene-polyoxyalkylene branched alkyl ether; [c] one or more surfactants selected from the group consisting of a primary amine, a secondary amine, a tertiary amine, and a quaternary ammonium; and [d] a polyanion, and measuring a substance formed or consumed in the reaction.
摘要翻译：一种用于测量样品中所含的低密度脂蛋白胆固醇的方法，其包括使样品与（i）胆固醇酯水解酶和胆固醇氧化酶的组合反应或（ii）胆固醇酯水解酶，氧化型辅酶和胆固醇脱氢酶在[a]聚氧乙烯 - 聚氧化烯烷基芳基醚的存在下; [b]一种或多种选自聚氧乙烯 - 聚氧化烯共聚物，聚氧乙烯烯基醚，聚氧乙烯支链烷基醚和聚氧乙烯 - 聚氧化烯支链烷基醚的表面活性剂; [c]一种或多种选自伯胺，仲胺，叔胺和季铵的表面活性剂; 和[d]聚阴离子，并测量反应中形成或消耗的物质。

2. 发明授权

US08685663B2 Method, reagent and kit for measuring cholesterol in low-density lipoproteins 有权
标题翻译：用于测量低密度脂蛋白胆固醇的方法，试剂和试剂盒
公开(公告)号：US08685663B2
公开(公告)日：2014-04-01
申请号：US13128444
申请日：2009-11-13
申请人： Tomomi Murakami , Tomoko Aratake , Shingo Mishima , Hideyuki Kuwata
发明人： Tomomi Murakami , Tomoko Aratake , Shingo Mishima , Hideyuki Kuwata
IPC分类号： C12Q1/60 , C12N9/16 , C12N9/04
CPC分类号： C12Q1/60 , C12Q1/26 , C12Q1/44 , G01N33/92 , G01N2800/044 , G01N2800/323
摘要： A method for measuring cholesterol in low-density lipoprotein contained in a sample, which comprises reacting a sample with (i) a combination of cholesterol ester hydrolase and cholesterol oxidase or (ii) a combination of cholesterol ester hydrolase, an oxidized coenzyme and cholesterol dehydrogenase in the presence of: [a] a polyoxyethylene-polyoxyalkylene alkylaryl ether; [b] one or more surfactants selected from the group consisting of a polyoxyethylene-polyoxyalkylene copolymer, a polyoxyethylene alkenyl ether, a polyoxyethylene branched alkyl ether, and a polyoxyethylene-polyoxyalkylene branched alkyl ether; [c] one or more surfactants selected from the group consisting of a primary amine, a secondary amine, a tertiary amine, and a quaternary ammonium; and [d] a polyanion, and measuring a substance formed or consumed in the reaction.
摘要翻译：一种用于测量样品中所含的低密度脂蛋白胆固醇的方法，其包括使样品与（i）胆固醇酯水解酶和胆固醇氧化酶的组合反应或（ii）胆固醇酯水解酶，氧化型辅酶和胆固醇脱氢酶在[a]聚氧乙烯 - 聚氧化烯烷基芳基醚的存在下; [b]一种或多种选自聚氧乙烯 - 聚氧化烯共聚物，聚氧乙烯烯基醚，聚氧乙烯支链烷基醚和聚氧乙烯 - 聚氧化烯支链烷基醚的表面活性剂; [c]一种或多种选自伯胺，仲胺，叔胺和季铵的表面活性剂; 和[d]聚阴离子，并测量反应中形成或消耗的物质。

3. 发明申请

US20130288283A1 METHOD FOR MEASURING COMPONENT TO BE MEASURED 有权
标题翻译：用于测量要测量的组件的方法
公开(公告)号：US20130288283A1
公开(公告)日：2013-10-31
申请号：US13991652
申请日：2011-12-12
申请人： Tomomi Murakami
发明人： Tomomi Murakami
IPC分类号： G01N21/77
CPC分类号： G01N21/77 , C09B21/00 , C12Q1/28 , G01N21/78 , G01N2333/908
摘要： The present invention provides a method for measuring a component to be measured in a sample, comprising converting the component to be measured in the sample into hydrogen peroxide and measuring the formed hydrogen peroxide in the presence of an α-keto acid using an oxidative-coloring chromogen. The present invention also provides a method for suppressing the influence of a peroxide on a method of converting a component to be measured in a sample into hydrogen peroxide and measuring the formed hydrogen peroxide using an oxidative-coloring chromogen, the suppression method comprising using an α-keto acid. The measuring method and the suppression method of the present invention using an α-keto acid suppress the influence of a peroxide to give an accurate measurement of the component to be measured in the sample.
摘要翻译：本发明提供了一种用于测量样品中要测量的组分的方法，包括将样品中待测量的组分转化为过氧化氢并在α-酮酸存在下使用氧化着色测量形成的过氧化氢色原本发明还提供了抑制过氧化物对样品中被测定成分转化为过氧化氢并使用氧化着色色原体测量形成的过氧化氢的方法的影响的方法，该方法包括使用α - 酸。使用α-酮酸的本发明的测量方法和抑制方法抑制过氧化物的影响，以准确测量样品中待测量的组分。

4. 发明授权

US07400556B2 Electronic timepiece with solar cell 失效
标题翻译：电子钟表带太阳能电池
公开(公告)号：US07400556B2
公开(公告)日：2008-07-15
申请号：US10541725
申请日：2003-12-12
申请人： Takashi Osa , Tomomi Murakami , Hitoshi Fujita
发明人： Takashi Osa , Tomomi Murakami , Hitoshi Fujita
IPC分类号： G04C10/00
CPC分类号： G04C10/02
摘要： An electronic timepiece with a solar cell includes a timepiece movement, a timepiece case for housing the timepiece movement, a casing ring for housing and holding the timepiece movement in the timepiece case, a solar cell and a dial. The solar cell is disposed almost vertically to a solar cell positioning portion provided in the casing ring, and the solar cell has a slender strip shape formed on a flexible substrate. Consequently, the solar cell is not disposed in the timepiece movement, and it is only necessary to change the casing ring as an external component even when a panel cover diameter is changed. Further, a solar cell can be coiled to match the size of the casing ring when it is incorporated in the casing ring, so that a common solar cell can be used despite a change in the panel cover diameter of the timepiece.
摘要翻译：具有太阳能电池的电子钟表包括钟表运动，用于容纳钟表运动的钟表壳体，用于容纳和保持钟表壳体中的钟表运动的壳环，太阳能电池和表盘。太阳能电池几乎垂直于设置在壳环中的太阳能电池定位部分，太阳能电池具有形成在柔性基板上的细长条形状。因此，太阳能电池不设置在钟表运动中，即使当面板盖直径改变时，仅需要改变作为外部部件的外壳。此外，太阳能电池可以被卷绕以匹配壳体环的尺寸，当壳体环被结合到壳体环中时，使得尽管钟表的面板盖直径发生变化，但是可以使用公共的太阳能电池。

5. 发明授权

US4083177A Liquid crystal display wrist watch 失效
标题翻译：液晶显示手表手表
公开(公告)号：US4083177A
公开(公告)日：1978-04-11
申请号：US508846
申请日：1974-09-24
申请人： Katsuo Nishimura , Tetsuya Yasuda , Tomomi Murakami , Masateru Yoshida , Minoru Natori , Yoshio Iinuma
发明人： Katsuo Nishimura , Tetsuya Yasuda , Tomomi Murakami , Masateru Yoshida , Minoru Natori , Yoshio Iinuma
IPC分类号： G02F1/13 , G04G9/00 , G04G17/06 , G04C3/00 , B21J7/12 , G04B29/00 , G04B33/00
CPC分类号： G04G17/06 , G02F1/13452 , G04G9/0035
摘要： A liquid crystal display wrist watch is disclosed which comprises a supporting frame secured to a wrist watch substrate. The frame has two perpendicularly crossing supporting surfaces which cooperate with two corresponding reference sides of a liquid crystal cell to determine the position of exterior electrodes of the liquid crystal cell and segment electrodes of an electronic circuit. A holding frame plate is used for detachably urging the liquid crystal against the suppporting frame. A boundary plate and color filter are each sandwiched between a movement and a protective glass cover. A portion is provided for determining the position of the holding frame plate, with respect to either to the movement or an outer case.

6. 发明授权

US4075825A Electronic timepiece substratum 失效
标题翻译：电子钟表底座
公开(公告)号：US4075825A
公开(公告)日：1978-02-28
申请号：US592099
申请日：1975-06-30
申请人： Tomomi Murakami , Masaru Yoshida , Satoshi Kimura , Tetuya Yasuda , Yoshio Iinuma
发明人： Tomomi Murakami , Masaru Yoshida , Satoshi Kimura , Tetuya Yasuda , Yoshio Iinuma
IPC分类号： G04G17/02 , G04C3/00 , G04B37/00
CPC分类号： G04G17/02
摘要： A watch body for an electronic watch containing an integrated circuit chip and a printed circuit board is disclosed. The watch body comprises an upper case and a bottom cover which are selectively interconnected one with the other. A lead package frame is sandwiched between the upper case and the bottom cover and contains a plurality of electrical leads disposed thereon and electrically coupled to the integrated circuit chip. The lead frame has first and second sides with the first side having a first cavity with the integrated circuit chip matingly engaged therein. The plurality of leads are disposed on the first side of the lead frame so as to surround this first cavity down the circuit chip. The second side of the lead frame has a second cavity with the printed circuit board disposed therein. By the use of the watch body of the instant invention, a significantly smaller number of components, a simpler manufacturing process is achieved.
摘要翻译：公开了一种含有集成电路芯片和印刷电路板的电子表的手表体。手表主体包括彼此选择性地互连的上壳体和底盖。引线封装框架夹在上壳体和底盖之间，并且包含多个设置在其上的电引线并电耦合到集成电路芯片。引线框架具有第一和第二侧，第一侧具有第一腔，其中集成电路芯片配合地接合在其中。多个引线设置在引线框架的第一侧上，以便沿着电路芯片包围该第一腔。引线框架的第二侧具有布置在其中的印刷电路板的第二腔。通过使用本发明的表体，可以实现显着更少数量的部件，实现更简单的制造工艺。

7. 发明授权

US3977176A Electronic watch structure 失效
标题翻译：电子手表结构
公开(公告)号：US3977176A
公开(公告)日：1976-08-31
申请号：US605921
申请日：1975-08-19
申请人： Tomomi Murakami , Hiromichi Nagata
发明人： Tomomi Murakami , Hiromichi Nagata
IPC分类号： G04G17/08 , G04C3/00 , A44C5/02
CPC分类号： G04G17/083
摘要： An electronic watch structure comprising separate molded plastic rectangular packages for the electronic watch movement and for the battery. The separate packages are mechanically and electrically connected together. The electronic watch movement package comprises two rectangular molded plastic halves having recesses, projections and hooks molded therein to hold the associated elements of the electronic watch movement in place. The movement package also includes a rectangular packing clamped between the halves of the package to form a waterproof seal. Furthermore, the battery in the battery package is electrically coupled to the electronic watch movement by conductive rubber composition members.

8. 发明授权

US09493433B2 Method for preserving aqueous solution containing leuco chromogen 有权
标题翻译：保存含有无色铬原子的水溶液的方法
公开(公告)号：US09493433B2
公开(公告)日：2016-11-15
申请号：US13811925
申请日：2011-08-09
申请人： Haruyo Soya , Tomomi Murakami , Haruki Tsunoda , Yu Ohsugi , Ayako Yoda , Masashi Matsushita
发明人： Haruyo Soya , Tomomi Murakami , Haruki Tsunoda , Yu Ohsugi , Ayako Yoda , Masashi Matsushita
IPC分类号： C09B21/00 , C09B67/00 , C09B67/42 , C07D279/30 , C09B67/28 , C09B67/44 , C12Q1/28 , G01N33/72 , C09B11/12
CPC分类号： C07D279/30 , C09B11/12 , C09B21/00 , C09B67/0077 , C09B67/0083 , C12Q1/28 , G01N33/723
摘要： Described is a method for preserving an aqueous solution comprising a leuco chromogen, comprising adding at least one compound selected from the group consisting of polyoxyethylene alkylamine and polyoxyethylene alkenylamine to the aqueous solution containing a leuco chromogen, and a method for stabilizing a leuco chromogen, comprising allowing the leuco chromogen to coexist in an aqueous solution comprising at least one compound selected from the group consisting of polyoxyethylene alkylamine and polyoxyethylene alkenylamine.
摘要翻译：描述了一种保存含有无色致发色素的水溶液的方法，包括将至少一种选自聚氧乙烯烷基胺和聚氧乙烯链烯基胺的化合物加入到含有无色致发色素的水溶液中，以及一种稳定无色发色体的方法，包括允许无色发色体共存于包含至少一种选自聚氧乙烯烷基胺和聚氧乙烯链烯基胺的化合物的水溶液中。

9. 发明申请

US20080312435A1 Imine Compound 审中-公开
标题翻译：亚胺化合物
公开(公告)号：US20080312435A1
公开(公告)日：2008-12-18
申请号：US11667728
申请日：2005-10-31
申请人： Shiuji Saito , Hiroshi Ohta , Tomoko Ishizaki , Mitsukane Yoshinaga , Makoto Tatsuzuki , Yuji Yokobori , Yasumitsu Tomishima , Aki Morita , Yoshihisa Toda , Kimiko Tokugawa , Ayaka Kaku , Tomomi Murakami , Hiromitsu Yoshimura , Shingo Sekine , Takao Yoshimizu
发明人： Shiuji Saito , Hiroshi Ohta , Tomoko Ishizaki , Mitsukane Yoshinaga , Makoto Tatsuzuki , Yuji Yokobori , Yasumitsu Tomishima , Aki Morita , Yoshihisa Toda , Kimiko Tokugawa , Ayaka Kaku , Tomomi Murakami , Hiromitsu Yoshimura , Shingo Sekine , Takao Yoshimizu
IPC分类号： C07D417/12 , C07D213/75 , C07D277/46 , C07D231/40 , C07D263/48
CPC分类号： C07D417/12 , C07D213/75 , C07D231/40 , C07D401/12 , C07D409/12 , C07D413/12
摘要： An imine compound represented by the formula: wherein A represents a heterocyclic group; R1, R2, an R3 each represent a hydrogen atom, a halogen atom, a C1-10 alkyl group optionally substituted with an aryl group(s) substituted with a halogen atom(s), a C3-10 cycloalkyl group, a C1-6 haloalkyl group, a C1-10 alkoxy group, etc.; R4 represents an optionally substituted C1-10 alkyl, C2-6 alkenyl, or aryl group; R5 represents a hydrogen atom, a C1-10 alkoxy group, a C1-6 haloalkyl group, an optionally substituted C1-10 alkyl or C2-6 alkenyl group, an optionally substituted aryl or heterocyclic group, etc.; W represents —CO—, —CO—CO—, —CO—NH—, —CS—NH—, or —SO2—, or a cannabinoid-receptor agonist comprising said imine compound as an active ingredient. The imine compound of the present invention has a cannabinoid-receptor agonist effect, and is useful as a therapeutic or prophylactic drug for pains and autoimmune diseases.
摘要翻译：由下式表示的亚胺化合物：其中A表示杂环基; R 1，R 2，R 3各自表示氢原子，卤素原子，任选被被卤素原子取代的芳基取代的C 1-10烷基，C 3-10环烷基， 6卤代烷基，C1-10烷氧基等; R 4表示任选取代的C 1-10烷基，C 2-6烯基或芳基; R5表示氢原子，C1-10烷氧基，C1-6卤代烷基，任选取代的C 1-10烷基或C 2-6烯基，任选取代的芳基或杂环基等; W表示-CO-，-CO-CO-，-CO-NH-，-CS-NH-或-SO 2 - 或包含所述亚胺化合物作为活性成分的大麻素受体激动剂。本发明的亚胺化合物具有大麻素受体激动剂作用，可用作疼痛和自身免疫疾病的治疗或预防药物。

10. 发明申请

US20060153011A1 Electronic timepiece with solar cell 失效
标题翻译：电子钟表带太阳能电池
公开(公告)号：US20060153011A1
公开(公告)日：2006-07-13
申请号：US10541725
申请日：2003-12-12
申请人： Takashi Osa , Tomomi Murakami , Hitoshi Fujita
发明人： Takashi Osa , Tomomi Murakami , Hitoshi Fujita
IPC分类号： G04C3/00 , G04B1/00
CPC分类号： G04C10/02
摘要： According to the present invention, in an electronic timepiece with a solar cell comprising a timepiece movement, a timepiece case for housing the timepiece movement, a casing ring for housing and holding the timepiece movement in the timepiece case, a solar cell and a dial, the solar cell is disposed almost vertically to a solar cell positioning portion provided in the casing ring, and the solar cell has a slender strip shape formed on a flexible substrate. Consequently, a solar cell need not be disposed in a timepiece movement, and it is only necessary to change a casing ring as an external component even when a panel cover diameter is changed, allowing a common use of a timepiece movement. Further, a solar cell can be coiled to match the size of a casing ring when it is incorporated in the casing ring, therefore a common solar cell can be used despite a change in the panel cover diameter of the timepiece.
摘要翻译：根据本发明，在具有包括钟表运动的太阳能电池的电子钟表中，用于容纳钟表运动的钟表壳体，用于容纳并保持钟表壳体中的钟表运动的壳环，太阳能电池和表盘，太阳能电池几乎垂直于设置在壳环中的太阳能电池定位部分，并且太阳能电池具有形成在柔性基板上的细长条形状。因此，太阳能电池不需要设置在钟表运动中，即使当面板盖直径变化时，仅需要改变作为外部部件的外壳，从而允许通常使用时计运动。此外，当太阳能电池被并入壳体环中时，可以将太阳能电池盘卷以匹配壳体环的尺寸，因此，尽管钟表的面板盖直径发生变化，但是可以使用普通的太阳能电池。

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