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1. 发明授权

US08877519B2 Chemical sensor element, sensing apparatus, and sensing method 有权
标题翻译：化学传感器元件，感测装置和传感方法
公开(公告)号：US08877519B2
公开(公告)日：2014-11-04
申请号：US12738228
申请日：2008-10-29
申请人： Tomohiro Yamada , Yoichiro Handa
发明人： Tomohiro Yamada , Yoichiro Handa
IPC分类号： G01N33/553 , G01N21/55 , G01N21/27
CPC分类号： G01N21/554 , G01N21/27 , Y10S436/805
摘要： A chemical sensor element contains a resonator having a first reflector in which particles of a fine metal structure are arranged two-dimensionally and periodically is counterposed with interposition of a dielectric layer to a second reflector, wherein the resonance wavelength of a resonator in which the entire of the first reflector is replaced by a metal thin film having the same thickness as the metal fine structure is different from the surface plasmon resonance wavelength induced in the metal fine structure; and the mode of the surface plasmon resonance excited in the metal fine structure is coupled with the mode of the resonator in which the entire of the first reflector is replaced by the metal thin film.
摘要翻译：化学传感器元件包括具有第一反射器的谐振器，其中精细金属结构的颗粒被二维地周期性布置，并且与第二反射器插入电介质层，其中整个谐振器的谐振波长由具有与金属精细结构相同的厚度的金属薄膜替换为与金属精细结构中诱发的表面等离子体共振波长不同的金属薄膜; 并且在金属精细结构中激发的表面等离子体激元谐振的模式与谐振器的模式耦合，其中整个第一反射器被金属薄膜代替。

2. 发明授权

US08570464B2 Optical filter, solid-state imaging element having the filter, and imaging apparatus 有权
标题翻译：滤光器，具有滤光器的固态成像元件和成像装置
公开(公告)号：US08570464B2
公开(公告)日：2013-10-29
申请号：US12824067
申请日：2010-06-25
申请人： Tomohiro Yamada , Ryo Kuroda
发明人： Tomohiro Yamada , Ryo Kuroda
IPC分类号： G02F1/1335 , G02B5/22
CPC分类号： G02B5/1809 , G02B5/203
摘要： An optical filter includes a substrate, and a periodic structure in which a plurality of members formed of silicon are periodically arranged on a surface of the substrate. The filter selectively transmits light of a first wavelength included in light incident on the periodic structure in the direction of the substrate. The members are two-dimensionally arranged with a period of 400 nm to 500 nm. The dimension of the members in the direction parallel to the surface is of 120 nm to 160 nm. A local maximum value of the transmission spectrum of the first wavelength is within the range of 400 nm to 500 nm.
摘要翻译：光学滤波器包括衬底，并且周期性结构，其中由硅形成的多个构件周期性地布置在衬底的表面上。滤光器选择性地透射入射在周期性结构上的光在基板的方向上包括的第一波长的光。构件以400nm至500nm的周期二维排列。构件在平行于表面的方向上的尺寸为120nm至160nm。第一波长的透射光谱的局部最大值在400nm至500nm的范围内。

3. 发明申请

US20130197009A1 ANTAGONIST FOR MUTANT ANDROGEN RECEPTOR 审中-公开
标题翻译：拮抗剂对突变型受体的拮抗作用
公开(公告)号：US20130197009A1
公开(公告)日：2013-08-01
申请号：US13877358
申请日：2011-10-21
申请人： Yukitaka Ideyama , Sadao Kuromitsu , Takashi Furutani , Masayoshi Takeda , Satoshi Konagai , Tomohiro Yamada , Nobuaki Taniguchi , Yutaka Kondoh , Masaaki Hirano , Kazushi Watanabe , Takashi Sugane , Akio Kakefuda
发明人： Yukitaka Ideyama , Sadao Kuromitsu , Takashi Furutani , Masayoshi Takeda , Satoshi Konagai , Tomohiro Yamada , Nobuaki Taniguchi , Yutaka Kondoh , Masaaki Hirano , Kazushi Watanabe , Takashi Sugane , Akio Kakefuda
IPC分类号： C07D401/02 , C07D401/14 , C07D403/02
CPC分类号： C07D401/02 , A61K31/496 , A61K31/506 , C07D401/12 , C07D401/14 , C07D403/02 , C07D403/12
摘要： [Problem] An object of the present invention is to provide a novel anticancer drug which is useful for treating prostate cancer accompanying androgen receptor mutation[Means for Solution] The present inventors conducted thorough research on mutant androgen-related diseases for which the traditional anti-androgen drugs become ineffective. As a result, they found that the compound, which is an active ingredient of the pharmaceutical composition of the present invention, exhibits an inhibitory action against transcriptional activation in a human mutant androgen receptor (AR), and has an excellent antitumor action in a human prostate cancer-bearing mouse, thereby completing the present invention. Accordingly, the compound, which is an active ingredient of the pharmaceutical composition of the present invention, is useful for a series of androgen receptor-related diseases including prostate cancer.
摘要翻译：本发明的目的在于提供一种可用于治疗伴随雄激素受体突变的前列腺癌的新型抗癌药物。本发明人进行了关于雄激素相关疾病的全面研究，雄激素药物变得无效。结果发现，作为本发明的药物组合物的活性成分的化合物在人突变型雄激素受体（AR）中表现出对转录活化的抑制作用，并且在人体中具有优异的抗肿瘤作用前列腺癌的小鼠，从而完成本发明。因此，作为本发明的药物组合物的活性成分的化合物可用于一系列与前列腺癌有关的雄激素受体相关疾病。

4. 发明授权

US08368898B2 Optical apparatus, optical detector, optical modulator, imaging apparatus, and camera 有权
标题翻译：光学设备，光学检测器，光学调制器，成像设备和照相机
公开(公告)号：US08368898B2
公开(公告)日：2013-02-05
申请号：US12852808
申请日：2010-08-09
申请人： Tomohiro Yamada
发明人： Tomohiro Yamada
IPC分类号： G01N21/55 , G02B5/26
CPC分类号： G02B5/008 , B82Y20/00 , G02B6/1226 , G02B6/3624
摘要： Provided is an optical apparatus having high durability, less optical absorption than a hole-type metal thin film filter, high transmittance and high reflectance, and variable optical characteristics. The apparatus includes: a dielectric substrate; a metal structure group including multiple metal structures two-dimensionally and discretely disposed at regular intervals; and a dielectric layer covering the metal structure group, in which: the metal structures have a first length equal to or shorter than a predetermined wavelength in a visible light region in one direction, and a second length equal to or shorter than the wavelength in a perpendicular direction; and the metal structures resonates with light entering the dielectric substrate or the dielectric layer, having a variable dielectric constant, to generate localized surface plasmon resonance on a surface of the metal structures to have a minimum transmittance or a maximum reflectance of the light having the wavelength.
摘要翻译：提供一种具有高耐久性，比空穴型金属薄膜滤光器的光吸收性低，透光率高，反射率高，光学特性可变的光学装置。该装置包括：电介质基片; 包括以规则间隔二维和离散地设置的多个金属结构的金属结构组; 以及覆盖所述金属结构体的介电层，其中：所述金属结构具有在一个方向上的可见光区域中等于或短于预定波长的第一长度，以及等于或短于一个方向上的波长的第二长度垂直方向并且金属结构与进入具有可变介电常数的电介质基板或电介质层的光谐振，以在金属结构的表面上产生局部表面等离子体共振，以具有波长最小的光的最小透射率或最大反射率。

5. 发明授权

US08321573B2 Communications terminal with optimum send interval 有权
标题翻译：通信终端具有最佳发送间隔
公开(公告)号：US08321573B2
公开(公告)日：2012-11-27
申请号：US11663068
申请日：2005-09-01
申请人： Keiji Hirao , Motoe Sakanaka , Tomohiro Yamada
发明人： Keiji Hirao , Motoe Sakanaka , Tomohiro Yamada
IPC分类号： G06F15/16
CPC分类号： H04M11/007 , H04L41/08 , H04L41/0806 , H04L41/0886 , H04M1/72533
摘要： A communication terminal includes a CPU (28). The CPU (28) issues to a router (16) a send request for requesting the router (16) to send an ask signal for repetitive responses to a server (14). Then, the ask signal is sent to the server (14) by the router (16), and a receive port is temporarily opened. From the server (14), a response signal is repeatedly sent in response to the ask signal. To the response signal, time information representative of a waiting time from receiving an ask signal to its reply is attached. A response signal sent back while the receive port is opened arrives at the communication terminal through the router (16), but a response signal sent back after the receive port is closed is discarded in the router (16). The CPU (28) repeatedly issues a send request to the router (16) regarding a time indicated by time information attached to the response signal lastly received as an issuance cycle (T).
摘要翻译：通信终端包括CPU（28）。 CPU（28）向路由器（16）发出请求路由器（16）向服务器（14）发送重复响应的询问信号的发送请求。然后，询问信号被路由器（16）发送到服务器（14），并且接收端口被暂时打开。从服务器（14），响应于询问信号重复地发送响应信号。对于响应信号，附加表示从接收询问信号到其答复的等待时间的时间信息。在接收端口打开时发回的响应信号通过路由器（16）到达通信终端，但在接收端口关闭后发回的响应信号在路由器（16）中被丢弃。 CPU（28）重复向路由器（16）发出关于由附加到最后接收的作为发行周期（T）的响应信号的时间信息指示的时间的发送请求。

6. 发明授权

US08154722B2 Sensor element structure, sensor element array, and manufacturing method of sensor element array 有权
标题翻译：传感器元件结构，传感器元件阵列和传感器元件阵列的制造方法
公开(公告)号：US08154722B2
公开(公告)日：2012-04-10
申请号：US11677890
申请日：2007-02-22
申请人： Tomohiro Yamada , Yoichiro Handa
发明人： Tomohiro Yamada , Yoichiro Handa
IPC分类号： G01J3/44
CPC分类号： G01N21/554 , G01N2021/258
摘要： Even when only a few antigens exist in a specimen, a change in a dielectric constant and a change in an optical spectrum accompanied thereto in the periphery of a conductive member are made larger, so that sensing at high sensitivity can be performed. A structure including a protrusion including a dielectric material protruded on a substrate and a conductive member provided on a first surface of the protrusion, in which the maximum value of the cross-sectional area in the cross-section in parallel with a first surface of the conductive member is larger than the area of the first surface.
摘要翻译：即使在试样中只存在少量抗原，导电性部件的周围的介电常数的变化和伴随其的光谱的变化也变大，可以进行高灵敏度的感测。一种结构，其特征在于，具有包括突出在基板上的介电材料的突起和设置在所述突起的第一面上的导电性部件，所述突起的横截面积的最大值与所述突起的第一面平行的截面积的最大值导电构件比第一表面的面积大。

7. 发明申请

US20120026504A1 LIGHT SOURCE APPARATUS AND IMAGE PICKUP APPARATUS EQUIPPED WITH SAME 失效
标题翻译：光源装置和图像拾取装置
公开(公告)号：US20120026504A1
公开(公告)日：2012-02-02
申请号：US13192921
申请日：2011-07-28
申请人： Tomohiro Yamada
发明人： Tomohiro Yamada
IPC分类号： G01B9/02 , H01S3/113 , H01S3/10
CPC分类号： G01B9/02091 , G01B9/02004 , H01S3/06791 , H01S3/08004 , H01S3/08059 , H01S3/10084 , H01S3/113 , H01S5/50 , H01S2301/04
摘要： A light source apparatus includes an optical resonator formed by an optical amplification medium and an optical switch. The optical switch includes a saturable absorber and changes its transmittance or reflectance when receiving an optical pulse emitted from a light irradiation source which includes a wavelength-tunable light source. The light source apparatus emits amplified light from the optical resonator in correspondence with the center wavelength of the optical pulse from the wavelength-tunable light source. The relationship between a length L and an effective refractive index n of the optical resonator and a repetition frequency f of the optical pulse satisfies a condition L (nL)/c.
摘要翻译：光源装置包括由光放大介质和光开关构成的光谐振器。光学开关包括可饱和吸收体，并在接收到包括波长可调光源的光照射源发射的光脉冲时，改变其透射率或反射率。光源装置对应于来自波长可调光源的光脉冲的中心波长，从光谐振器发射放大的光。光谐振器的长度L和有效折射率n之间的关系以及光脉冲的重复频率f满足条件L （nL）/ c。

8. 发明申请

US20110304853A1 WAVELENGTH SWEEPING LIGHT SOURCE AND IMAGING APPARATUS USING THE SAME 有权
标题翻译：波长扫描光源和成像装置使用它
公开(公告)号：US20110304853A1
公开(公告)日：2011-12-15
申请号：US13154127
申请日：2011-06-06
申请人： Tomohiro Yamada , Kentaro Furusawa
发明人： Tomohiro Yamada , Kentaro Furusawa
IPC分类号： G01B9/02 , H01S3/10
CPC分类号： G01B9/02007 , G01B9/02004 , G01B9/02027 , G01B9/02091 , H01S3/08013 , H01S3/083 , H01S3/10046 , H01S5/0085 , H01S5/0656 , H01S5/0657 , H01S5/06835 , H01S5/14 , H01S5/4012 , H01S5/4087
摘要： A light source apparatus includes a laser oscillator equipped with a first optical resonator, a plurality of second optical resonators including input portions respectively connected in parallel to the first optical resonator, a plurality of light extraction units configured to extract a light beam from an output portion of each second optical resonator, and a light multiplexing unit configured to multiplex the light beam extracted from each light extraction unit, wherein the light source apparatus causes the light multiplexing unit to output a multiplexed light beam passed through the plurality of second optical resonators, an optical member having refractive index dispersion and an optical amplification medium are disposed in each of the plurality of second optical resonators, and the optical amplification media of the plurality of second optical resonators are different from each other in maximum gain wavelength.
摘要翻译：光源装置包括配备有第一光谐振器的激光振荡器，包括分别并联连接到第一光谐振器的输入部分的多个第二光谐振器，多个光提取单元，被配置为从输出部分以及光复用单元，其被配置为对从每个光提取单元提取的光束进行多路复用，其中所述光源装置使所述光复用单元输出通过所述多个第二光谐振器的复用光束，具有折射率色散的光学构件和光学放大介质设置在多个第二光学谐振器中的每一个中，多个第二光学谐振器的光学放大介质在最大增益波长方面彼此不同。

9. 发明申请

US20110034321A1 CATALYST AND PROCESS FOR PRODUCING THE SAME 有权
标题翻译：催化剂及其制备方法
公开(公告)号：US20110034321A1
公开(公告)日：2011-02-10
申请号：US12988072
申请日：2009-04-13
申请人： Takuya Hatagishi , Tomohiro Yamada
发明人： Takuya Hatagishi , Tomohiro Yamada
IPC分类号： B01J29/48 , C01B39/38
CPC分类号： F26B3/12 , B01J29/06 , B01J29/076 , B01J29/08 , B01J29/16 , B01J29/40 , B01J29/48 , B01J29/70 , B01J29/78 , B01J35/002 , B01J35/023 , B01J37/0036 , B01J37/0045 , B01J2229/186 , C07C2/76 , C07C2521/06 , C07C2521/08 , C07C2521/12 , C07C2523/22 , C07C2523/26 , C07C2523/28 , C07C2523/30 , C07C2523/36 , C07C2529/06 , C07C2529/08 , C07C2529/40 , C07C2529/83 , C07C2529/89 , Y02P20/588 , C07C15/00
摘要： [Task] To provide a catalyst in which granules of the catalyst are improved in crash strength with no use of the caking agent, while increasing the effective area of the crystal surface part of the catalyst.[Solving Means] A catalyst powder-containing slurry obtained by milling a metallosilicate-containing raw material by a bead mill is dried by a spray drying method to obtain granules of a catalyst. The raw material may be one containing a metallosilicate having micropores of a size that is substantially 4.5 to 6.5 angstroms. It is better to mill the raw material by a bead mill such that the particle size of the metallosilicate becomes 1.0 μm or less at a cumulative frequency of 50%. It is better that as a metal component at least one metal component selected from rhenium, vanadium, molybdenum, tungsten, chromium, and their compounds is supported on the metallosilicate. It is better to subject the slurry to the drying process after aging. It is better to add polyvinyl alcohol to the slurry.[Selected Drawing] None
摘要翻译： [任务]提供催化剂，其中催化剂的颗粒在碰撞强度方面得到改善，而不使用结块剂，同时增加催化剂的晶体表面部分的有效面积。 [解决方案]通过用珠磨机研磨含有金属硅酸盐的原料获得的含催化剂粉末的浆料通过喷雾干燥法干燥以获得催化剂颗粒。原料可以是含有大体为4.5〜6.5埃的微孔的金属硅酸盐的原料。最好用珠磨机研磨原料，使得金属硅酸盐的粒径在累积频率为50％时变成1.0μm以下。更好的是，作为金属成分，至少一种选自铼，钒，钼，钨，铬及其化合物的金属组分负载在金属硅酸盐上。老化后将浆料置于干燥过程最好。最好将聚乙烯醇加入到浆料中。 [已选图]无

10. 发明授权

US07729499B2 Speaker apparatus and reproducing apparatus 失效
标题翻译：扬声器装置和再现装置
公开(公告)号：US07729499B2
公开(公告)日：2010-06-01
申请号：US11418069
申请日：2006-05-05
申请人： Wataru Kokubo , Tomohiro Yamada
发明人： Wataru Kokubo , Tomohiro Yamada
IPC分类号： H04R25/00
CPC分类号： H04R5/02
摘要： The present invention provides a speaker apparatus and reproducing apparatus with no limitation on their listening areas. The apparatus includes; the housing 2 substantially in the shape of a spheroid; the left speaker 5A, which is attached to the left end of the long side of the housing 2 such that the left speaker 5A faces outwardly of the housing 2; and the right speaker 5B, which is attached to the right end of the long side of the housing 2 such that the right speaker 5B faces outwardly of the housing 2. Therefore, the left speaker 5A and the right speaker 5B are approximately equivalent to a point sound source, and the sound from the left speaker 5A and the right speaker 5B smoothly radiates from the housing 2 in every direction. Thus, a listener can have good quality of sound from anywhere around the housing.
摘要翻译：本发明提供一种扬声器装置和再现装置，而不限制其收听区域。该装置包括：壳体2基本上为球体的形状; 左扬声器5A，其附接到壳体2的长边的左端，使得左扬声器5A面向外壳2的外侧; 右侧扬声器5B与壳体2的长边的右端连接，使得右扬声器5B面向壳体2的外侧。因此，左扬声器5A和右扬声器5B大致相当于并且来自左扬声器5A和右扬声器5B的声音从壳体2在每个方向上平滑地散射。因此，听众可以从房屋周围的任何地方获得良好的声音质量。

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