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1. 发明授权

US06626857B1 Extracorporeal circulation device and method for isolation temperature control method 有权
标题翻译：体外循环装置及隔离温度控制方法
公开(公告)号：US06626857B1
公开(公告)日：2003-09-30
申请号：US09856135
申请日：2001-07-23
申请人： Tomio Ohta , Tetsuya Miyatake , Yoshihiko Kinoshita , Tomoya Murakami
发明人： Tomio Ohta , Tetsuya Miyatake , Yoshihiko Kinoshita , Tomoya Murakami
IPC分类号： A61M3700
CPC分类号： A61M1/3455 , A61M1/3441 , A61M1/3458 , A61M1/369 , A61M2230/207
摘要： An extracorporeal circulation apparatus used for the selective temperature controlling method in which a temperature of an object is kept at a predetermined temperature, includes: (A) a fluid replacement supply unit which quantitatively supplies a fluid replacement of which temperature has been adjusted into a blood vessel; (B) a blood concentration unit which quantitatively withdraws blood diluted by the fluid replacement from a blood vessel and concentrates the withdrawn diluted blood; and (C) a blood supply unit which controls a temperature of the blood which has been concentrated and quantitatively supplies the concentrated blood into a blood vessel, the blood concentration unit comprising a diluted blood temperature sensor which measures a temperature of the withdrawn diluted blood, and the fluid replacement supply unit including a means which controls a temperature of the fluid replacement to be supplied based on a different extent between the measured diluted blood temperature and the predetermined temperature of the object.
摘要翻译：一种用于选择温度控制方法的体外循环装置，其中物体的温度保持在预定温度，包括：（A）液体替换供应单元，其将已经调节了温度的液体置换定量为血液容器;（B）血液浓度单元，其定量地从血管中取出由液体替换物稀释的血液，并浓缩取出的稀释血液; 和（C）血液供给单元，其对已经浓缩并定量地将浓缩血液供给到血管中的血液的温度进行控制，所述血液浓度单元包括测定取出的稀释血液的温度的稀释型血液温度传感器，并且所述流体置换供给单元包括基于所测量的稀释血液温度和所述物体的预定温度之间的不同程度控制要供应的所述流体置换的温度的装置。

2. 发明授权

US10179382B2 Pallet transport system of machine tool 有权
公开(公告)号：US10179382B2
公开(公告)日：2019-01-15
申请号：US13980537
申请日：2011-02-15
申请人： Masaaki Miyazaki , Tomoya Murakami
发明人： Masaaki Miyazaki , Tomoya Murakami
IPC分类号： B23Q7/00 , B23Q7/14 , B23Q3/18
摘要： A pallet transport system of a machine tool promoting transport of a pallet for workpiece mounting use from a first stand to an adjoining second stand, wherein the first stand has a first mounting part which defines a first mounting surface, the second stand has a second mounting part which defines a second mounting surface, and the pallet has a mounted part attachable to the first and second mounting parts, along a transport direction of the pallet, includes a support mechanism turnably supporting at least one of the first stand, the second stand, and the pallet so that the orientations of a mounted surface defined by the mounted part and the second mounting surface match due to contact force between the mounted part and the second mounting part along with transport of the pallet from the first stand to the second stand along the first mounting surface.

3. 发明申请

US20110139690A1 ERROR CORRECTION FOR A LIQUID CONCENTRATION DETECTOR OF A BLOOD PURIFICATION APPARATUS 有权
标题翻译：血液净化装置的液体浓度检测器的错误校正
公开(公告)号：US20110139690A1
公开(公告)日：2011-06-16
申请号：US12967562
申请日：2010-12-14
申请人： Kunihiko Akita , Tomoya Murakami , Takayuki Hirano , Yasushi Takakuwa
发明人： Kunihiko Akita , Tomoya Murakami , Takayuki Hirano , Yasushi Takakuwa
IPC分类号： A61M1/36
CPC分类号： A61M1/367 , A61M1/1692 , A61M2205/3306 , G01N21/05 , G01N21/274 , G01N21/59 , G01N2201/062 , G01N2201/0621
摘要： A blood purification instrument for extracorporeally circulating a patient's blood and a concentration detector detects a concentration of liquid during blood purification wherein the concentration detector has a light emitter irradiating light onto the liquid, a light receiver receives the light as transmitted through the liquid, a reference light receiver receives reference light branched from the light emitter without transmission through the liquid, and a detector detecting the light intensity respectively of the transmitted light and the reference light received by the light receiver and the reference light receiver, respectively. The blood purification apparatus further includes an error corrector detecting the concentration of the liquid based on the received light intensity of the light received by the light receiver and detected by the detector and for correcting a detected error of the concentration detector based on the received light intensity of the reference light received by the reference light receiver.
摘要翻译：用于体外循环患者血液的血液净化装置和浓度检测器检测血液净化期间的液体浓度，其中浓度检测器具有将发光体照射到液体上的发光体，光接收器接收透过液体的光，参考光接收器接收从光发射器分支的参考光，而不透射通过液体;检测器分别检测由光接收器和参考光接收器接收的透射光和参考光的光强度。血液净化装置还包括误差校正器，其基于由光接收器接收并由检测器检测到的光的接收光强度来检测液体的浓度，并且用于基于接收的光强度校正浓度检测器的检测误差由参考光接收器接收的参考光。

4. 发明授权

US07931610B2 Blood purification apparatus 有权
标题翻译：血液净化装置
公开(公告)号：US07931610B2
公开(公告)日：2011-04-26
申请号：US12174742
申请日：2008-07-17
申请人： Tomoya Murakami , Masahiro Toyoda , Akari Agata
发明人： Tomoya Murakami , Masahiro Toyoda , Akari Agata
IPC分类号： C02F1/44 , A61M37/00
CPC分类号： A61M1/3653 , A61M1/361 , A61M1/3612 , A61M1/3658
摘要： A blood purification apparatus that can make the specific peak to be imparted to the blood more distinct, and therefore can detect blood recirculation reliably and precisely, is presented. It contains a blood circuit route, a blood pump, a dialyzer, dialysate introduction and discharge lines, a duplex pump, a pressurizing pump, a blood concentration means, and detection means that detect the specific peak imparted by the blood concentration means. The blood concentration means is configured to have an atmosphere release line, the tip of which is open to the atmosphere, that extends from between the pressurizing pump and the duplex pump in the dialysate discharge line, and to have an electromagnetic valve that can open or close the atmosphere release line. The electromagnetic valve opens the atmosphere release line to impart the specific peak by rapidly concentrating the blood flowing in the dialyzer for a short period of time.
摘要翻译：可以使血液净化装置能够使特定的峰值赋予血液更加清晰，因此可以可靠且精确地检测血液循环。它包含血液回路，血液泵，透析器，透析液引入和排出管线，双相泵，加压泵，血液浓缩装置和检测由血液浓度装置赋予的特定峰值的检测装置。血液浓度装置被配置为具有气体释放管线，其顶端向大气开放，其从透析液排出管线中的加压泵和双相泵之间延伸，并且具有能够打开的电磁阀或关闭气氛释放线。电磁阀打开大气释放线，以通过快速浓缩在透析器中流动的血液短时间来赋予特定峰值。

5. 发明申请

US20130302128A1 PALLET TRANSPORT SYSTEM OF MACHINE TOOL 审中-公开
标题翻译：机械工具运输系统
公开(公告)号：US20130302128A1
公开(公告)日：2013-11-14
申请号：US13980537
申请日：2011-02-15
申请人： Masaaki Miyazaki , Tomoya Murakami
发明人： Masaaki Miyazaki , Tomoya Murakami
IPC分类号： B23Q7/00
CPC分类号： B23Q7/00 , B23Q3/186 , B23Q7/1426 , Y10T29/5196
摘要： A pallet transport system of a machine tool promoting transport of a pallet for workpiece mounting use from a first stand to an adjoining second stand, wherein the first stand has a first mounting part which defines a first mounting surface, the second stand has a second mounting part which defines a second mounting surface, and the pallet has a mounted part attachable to the first and second mounting parts, along a transport direction of the pallet, includes a support mechanism turnably supporting at least one of the first stand, the second stand, and the pallet so that the orientations of a mounted surface defined by the mounted part and the second mounting surface match due to contact force between the mounted part and the second mounting part along with transport of the pallet from the first stand to the second stand along the first mounting surface.
摘要翻译：一种用于促进从第一支架到相邻的第二支架的用于工件安装使用的托盘的托盘输送系统，其中所述第一支架具有限定第一安装表面的第一安装部分，所述第二支架具有第二安装该部分限定第二安装表面，并且托盘具有可沿着托盘的输送方向附接到第一和第二安装部分的安装部分，包括可转动地支撑第一支架，第二支架，以及托盘，使得由安装部分和第二安装表面限定的安装表面的方位由于安装部件和第二安装部件之间的接触力而匹配，同时托盘从第一支架传送到第二支架第一个安装面。

6. 发明授权

US08518247B2 Error correction for a liquid concentration detector of a blood purification apparatus 有权
标题翻译：血液净化装置的液体浓度检测器的误差校正
公开(公告)号：US08518247B2
公开(公告)日：2013-08-27
申请号：US12967562
申请日：2010-12-14
申请人： Kunihiko Akita , Tomoya Murakami , Takayuki Hirano , Yasushi Takakuwa
发明人： Kunihiko Akita , Tomoya Murakami , Takayuki Hirano , Yasushi Takakuwa
IPC分类号： B01D61/30
CPC分类号： A61M1/367 , A61M1/1692 , A61M2205/3306 , G01N21/05 , G01N21/274 , G01N21/59 , G01N2201/062 , G01N2201/0621
摘要： A blood purification instrument for extracorporeally circulating a patient's blood and a concentration detector detects a concentration of liquid during blood purification wherein the concentration detector has a light emitter irradiating light onto the liquid, a light receiver receives the light as transmitted through the liquid, a reference light receiver receives reference light branched from the light emitter without transmission through the liquid, and a detector detecting the light intensity respectively of the transmitted light and the reference light received by the light receiver and the reference light receiver, respectively. The blood purification apparatus further includes an error corrector detecting the concentration of the liquid based on the received light intensity of the light received by the light receiver and detected by the detector and for correcting a detected error of the concentration detector based on the received light intensity of the reference light received by the reference light receiver.
摘要翻译：用于体外循环患者血液的血液净化装置和浓度检测器检测血液净化期间的液体浓度，其中浓度检测器具有将发光体照射到液体上的发光体，光接收器接收透过液体的光，参考光接收器接收从光发射器分支的参考光，而不透射通过液体;检测器分别检测由光接收器和参考光接收器接收的透射光和参考光的光强度。血液净化装置还包括误差校正器，其基于由光接收器接收并由检测器检测到的光的接收光强度来检测液体的浓度，并且用于基于接收的光强度校正浓度检测器的检测误差由参考光接收器接收的参考光。

7. 发明申请

US20080103427A1 BLOOD PURIFICATION DEVICE 审中-公开
标题翻译：血液净化装置
公开(公告)号：US20080103427A1
公开(公告)日：2008-05-01
申请号：US11863493
申请日：2007-09-28
申请人： Masahiro Toyoda , Tomoya Murakami
发明人： Masahiro Toyoda , Tomoya Murakami
IPC分类号： A61M1/14
CPC分类号： A61M1/16 , A61M1/1613 , A61M1/3609 , A61M1/361 , A61M1/3612 , A61M1/3658 , A61M2205/3313 , A61M2205/50 , A61M2230/207
摘要： A blood purification device capable of performing an ideal blood purification treatment which accounts for blood recirculation is provided. That is, a blood purification device is furnished with a blood circuit containing an arterial blood circuit and a venous blood circuit for circulating blood outside the body, a dialyzer for purifying blood flowing in the blood circuit, hematocrit sensors for measuring the hematocrit value of blood circulating outside the body in the blood circuit, and a recirculation rate derivation means for obtaining a recirculation rate, and further provided with a true value derivation means for obtaining a patient's true hematocrit value based on the recirculation rate obtained by the recirculation rate derivation means.
摘要翻译：提供能够进行考虑血液再循环的理想的血液净化处理的血液净化装置。也就是说，血液净化装置配备有包含动脉血回路的血液回路和用于使体外循环血液的静脉血回路，用于净化血液回路中流动的血液的透析器，用于测量血液的血细胞比容值的血细胞比容传感器在血液循环体外循环，以及用于获得再循环率的再循环速率导出装置，并且还具有真值推定装置，用于根据再循环速率导出装置获得的再循环速度获得患者的真实血细胞比容值。

8. 发明授权

US09212988B2 Liquid concentration detector for a blood purification apparatus 有权
标题翻译：用于血液净化装置的液体浓度检测器
公开(公告)号：US09212988B2
公开(公告)日：2015-12-15
申请号：US12967643
申请日：2010-12-14
申请人： Kunihiko Akita , Tomoya Murakami , Takayuki Hirano , Yasushi Takakuwa
发明人： Kunihiko Akita , Tomoya Murakami , Takayuki Hirano , Yasushi Takakuwa
IPC分类号： B01D11/00 , B01D61/00 , C02F1/44 , G01N21/27 , A61M1/16 , G01N21/59 , G01N21/05
CPC分类号： G01N21/274 , A61M1/16 , A61M1/1609 , A61M2205/15 , A61M2205/3306 , A61M2205/3313 , G01N21/05 , G01N21/59 , G01N2201/0621 , G01N2201/0626
摘要： A blood purification apparatus includes a blood purification instrument for extracorporeally circulating blood of a patient and a concentration detector detecting a concentration of liquid flowing during blood purification. The concentration detector has a light emitter irradiating light onto said liquid, a light receiver receiving light from the light emitter transmitted through said liquid, and a detector detecting the received light intensity received by the light receiver. The concentration detector detects the concentration of the liquid based on the received light intensity and can be calibrated by adjusting an amount of irradiation by the light emitter so that the received light intensity has a predetermined value.
摘要翻译：血液净化装置包括：用于体外循环患者血液的血液净化装置和检测血液净化期间流动的液体浓度的浓度检测器。浓度检测器具有将光照射到所述液体上的发光体，接收来自透射通过所述液体的发光体的光的光接收器，以及检测由光接收器接收的接收光强度的检测器。浓度检测器基于接收的光强度检测液体的浓度，并且可以通过调节光发射器的照射量来校准，使得接收的光强度具有预定值。

9. 发明申请

US20110144459A1 LIQUID CONCENTRATION DETECTOR FOR A BLOOD PURIFICATION APPARATUS 有权
标题翻译：用于血液净化装置的液体浓度检测器
公开(公告)号：US20110144459A1
公开(公告)日：2011-06-16
申请号：US12967643
申请日：2010-12-14
申请人： Kunihiko Akita , Tomoya Murakami , Takayuki Hirano , Yasushi Takakuwa
发明人： Kunihiko Akita , Tomoya Murakami , Takayuki Hirano , Yasushi Takakuwa
IPC分类号： A61B5/1455
CPC分类号： G01N21/274 , A61M1/16 , A61M1/1609 , A61M2205/15 , A61M2205/3306 , A61M2205/3313 , G01N21/05 , G01N21/59 , G01N2201/0621 , G01N2201/0626
摘要： A blood purification apparatus includes a blood purification instrument for extracorporeally circulating blood of a patient and a concentration detector detecting a concentration of liquid flowing during blood purification. The concentration detector has a light emitter irradiating light onto said liquid, a light receiver receiving light from the light emitter transmitted through said liquid, and a detector detecting the received light intensity received by the light receiver. The concentration detector detects the concentration of the liquid based on the received light intensity and can be calibrated by adjusting an amount of irradiation by the light emitter so that the received light intensity has a predetermined value.
摘要翻译：血液净化装置包括：用于体外循环患者血液的血液净化装置和检测血液净化期间流动的液体浓度的浓度检测器。浓度检测器具有将光照射到所述液体上的发光体，接收来自透射通过所述液体的发光体的光的光接收器，以及检测由光接收器接收的接收光强度的检测器。浓度检测器基于接收的光强度检测液体的浓度，并且可以通过调节光发射器的照射量来校准，使得接收的光强度具有预定值。

10. 发明申请

US20090054822A1 BLOOD PURIFICATION APPARATUS 有权
标题翻译：血液净化装置
公开(公告)号：US20090054822A1
公开(公告)日：2009-02-26
申请号：US12174742
申请日：2008-07-17
申请人： Tomoya Murakami , Masahiro Toyoda , Akari Agata
发明人： Tomoya Murakami , Masahiro Toyoda , Akari Agata
IPC分类号： A61M1/14
CPC分类号： A61M1/3653 , A61M1/361 , A61M1/3612 , A61M1/3658
摘要： A blood purification apparatus that can make the specific peak to be imparted to the blood more distinct, and therefore can detect blood recirculation reliably and precisely, is presented. It contains a blood circuit route, a blood pump, a dialyzer, dialysate introduction and discharge lines, a duplex pump, a pressurizing pump, a blood concentration means, and detection means that detect the specific peak imparted by the blood concentration means. The blood concentration means is configured to have an atmosphere release line, the tip of which is open to the atmosphere, that extends from between the pressurizing pump and the duplex pump in the dialysate discharge line, and to have an electromagnetic valve that can open or close the atmosphere release line. The electromagnetic valve opens the atmosphere release line to impart the specific peak by rapidly concentrating the blood flowing in the dialyzer for a short period of time.
摘要翻译：可以使血液净化装置能够使特定的峰值赋予血液更加清晰，因此可以可靠且精确地检测血液循环。它包含血液回路，血液泵，透析器，透析液引入和排出管线，双相泵，加压泵，血液浓缩装置和检测由血液浓度装置赋予的特定峰值的检测装置。血液浓度装置被配置为具有气体释放管线，其顶端向大气开放，其从透析液排出管线中的加压泵和双相泵之间延伸，并且具有能够打开的电磁阀或关闭气氛释放线。电磁阀打开大气释放线，以通过快速浓缩在透析器中流动的血液短时间来赋予特定峰值。

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