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1. 发明授权

US07481759B2 Systems and methods for treatment of coronary artery disease 失效
标题翻译：用于治疗冠状动脉疾病的系统和方法
公开(公告)号：US07481759B2
公开(公告)日：2009-01-27
申请号：US10211463
申请日：2002-08-02
申请人： Todd K. Whitehurst , James P McGivern , Kelly H McClure , Mark R. Stultz
发明人： Todd K. Whitehurst , James P McGivern , Kelly H McClure , Mark R. Stultz
IPC分类号： A61N1/36
CPC分类号： A61N1/36114 , A61M5/14276 , A61M2205/3523 , A61M2205/8206 , A61M2230/06
摘要： Methods and systems for treatment of coronary artery disease (CAD) include implantation of the discharge portion(s) of a catheter and, optionally, electrodes on a lead, near the tissue(s) to be stimulated. Stimulation pulses, i.e., drug infusion pulses and optional electrical pulses, are supplied by a stimulator implanted remotely, and through the catheter or lead, which is tunneled subcutaneously between the stimulator and stimulation site. Stimulation sites include the coronary arteries, the aorta, the left ventricle, the left atrium, and/or the pulmonary veins, among other locations. Disclosed treatments include drugs used for acute treatment of CAD, for chronic treatment of CAD, to promote angiogenesis, and/or as AGE Crosslink Breakers, among other drugs. For instance, the systems and methods reduce or eliminate the incidence of CAD and related morbidities, improve symptoms resulting from CAD, and/or improve cardiac blood flow, cardiac function, and patient quality of life.
摘要翻译：用于治疗冠状动脉疾病（CAD）的方法和系统包括将导管的放电部分和可选地在导线上的电极植入，以被刺激的组织附近。刺激脉冲，即药物输注脉冲和可选的电脉冲由远程植入的刺激器，以及通过在刺激器和刺激部位之间皮下隧穿的导管或引线提供。刺激部位包括冠状动脉，主动脉，左心室，左心房和/或肺静脉等。公开的治疗包括用于急性治疗CAD，用于慢性CAD治疗，促进血管发生的药物和/或作为AGE交联断裂剂等药物。例如，系统和方法可减少或消除CAD和相关疾病的发生率，改善由CAD引起的症状和/或改善心脏血流量，心脏功能和患者生活质量。

2. 发明授权

US07566314B2 Portable cervical traction device 有权
标题翻译：便携式颈椎牵引装置
公开(公告)号：US07566314B2
公开(公告)日：2009-07-28
申请号：US11422231
申请日：2006-06-05
申请人： H. Duane Saunders , Mark R. Stultz
发明人： H. Duane Saunders , Mark R. Stultz
IPC分类号： A61F5/00
CPC分类号： A61F5/04 , A61H1/0222 , A61H1/0296 , A61H2201/0157 , A61H2201/0161 , A61H2201/0192 , A61H2201/1246 , A61H2201/1607 , A61H2201/1628 , A61H2201/1664 , A61H2201/5053 , A61H2203/0456
摘要： Low-cost, light weight portable cervical traction or spinal decompression devices for home use by a patient. A carriage is slidable along a portion of a support structure parallel to a longitudinal axis. The carriage includes a restraining mechanism adapted to releasably restrain a portion of a patient's body to the carriage. The pneumatic traction force generating apparatus is operatively coupled to move the carriage relative to the support structure when in a pressurized state. The pneumatic traction force generating apparatus is adapted to maintain a generally static traction force during a treatment period when in the pressurized state without additional pressurized air being supplied. A hand pump operated by the patient is fluidly connected to the pneumatic traction force generating apparatus to inject pressurized air. The hand pump is capable of injecting at least 138 kPa (20 psi) of pressure into the pneumatic traction force generating apparatus. A pressure relief mechanism operated by the patient is adapted to release pressure from the pneumatic traction force generating apparatus.
摘要翻译：低成本，重量轻的便携式颈椎牵引或脊柱减压装置，供患者家庭使用。滑架可沿平行于纵向轴线的支撑结构的一部分滑动。托架包括适于将患者身体的一部分可释放地限制在托架上的约束机构。当处于加压状态时，气动牵引力产生装置可操作地联接以相对于支撑结构移动滑架。气动牵引力发生装置适于在处于加压状态的处理期间保持大体静态的牵引力，而不需要额外的加压空气供给。由患者操作的手动泵流体地连接到气动牵引力产生装置以注入加压空气。手动泵能够将至少138kPa（20psi）的压力注入到气动牵引力产生装置中。由患者操作的减压机构适于从气动牵引力产生装置释放压力。

3. 发明授权

US07108671B2 Portable lumbar traction device 有权
标题翻译：便携式腰椎牵引装置
公开(公告)号：US07108671B2
公开(公告)日：2006-09-19
申请号：US10751688
申请日：2004-01-05
申请人： H. Duane Saunders , Mark R. Stultz
发明人： H. Duane Saunders , Mark R. Stultz
IPC分类号： A61F5/00
CPC分类号： A61F5/04 , A61H1/0222 , A61H1/0296 , A61H2201/0157 , A61H2201/0161 , A61H2201/0192 , A61H2201/1246 , A61H2201/1607 , A61H2201/1628 , A61H2201/1664 , A61H2201/5053 , A61H2203/0456
摘要： A low-cost, light weight portable lumbar fraction device for home use by a patient including a support structure having a longitudinal axis and a carriage slidable along a portion of the support structure parallel to the longitudinal axis. The carriage includes a restraining mechanism adapted to releasably restrain a portion of a patient's body to the carriage. The pneumatic fraction force generating apparatus includes at least one pneumatic chamber and at least one air inlet. The pneumatic traction force generating apparatus is operatively coupled to both the carriage and the support structure to move the carriage relative to the support structure when the at least one pneumatic chamber is in a pressurized state. The pneumatic fraction force generating apparatus is adapted to maintain a generally static fraction force for a period in excess of 10 minutes when in the pressurized state without additional pressurized air being supplied. A hand pump operated by the patient is fluidly connected to the at least one pneumatic chamber for injecting pressurized air into the at least one pneumatic chamber. The hand pump is capable of injecting at least 138 kPa (20 psi) of pressure into the pneumatic chamber. A pressure relief mechanism operated by the patient is adapted to release pressure from the at least one pneumatic chamber.
摘要翻译：一种用于家庭使用的低成本，轻便便携式腰部分装置，包括具有纵向轴线的支撑结构和可沿着平行于纵向轴线的支撑结构的一部分滑动的滑架。托架包括适于将患者身体的一部分可释放地限制在托架上的约束机构。所述气动分级力产生装置包括至少一个气动室和至少一个空气入口。当至少一个气动室处于加压状态时，气动牵引力产生装置可操作地联接到滑架和支撑结构两者以相对于支撑结构移动滑架。气动分级力产生装置适于在加压状态下保持大体静态分数力超过10分钟的时间，而不需要额外的加压空气供给。由患者操作的手动泵流体地连接到至少一个气动室，用于将加压空气注入到至少一个气动室中。手动泵能够将至少138 kPa（20 psi）的压力注入气动室。由患者操作的减压机构适于从至少一个气动室释放压力。

4. 发明授权

US06506174B1 Portable traction device 失效
标题翻译：便携式牵引装置
公开(公告)号：US06506174B1
公开(公告)日：2003-01-14
申请号：US08817444
申请日：1997-10-22
申请人： H. Duane Saunders , Mark R. Stultz
发明人： H. Duane Saunders , Mark R. Stultz
IPC分类号： A61F500
CPC分类号： A61F5/04 , A61H1/0222 , A61H1/0296 , A61H2201/0157 , A61H2201/0161 , A61H2201/0192 , A61H2201/1246 , A61H2201/1607 , A61H2201/1628 , A61H2201/1664 , A61H2201/5053 , A61H2203/0456
摘要： A portable traction device suitable for cervical or lumbar traction powered by a pneumatic cylinder. The portable traction device includes a support structure having a longitudinal axis and a carriage slidable along a portion of the support structure parallel to the longitudinal axis. The carriage including restraining mechanism for releasably restraining a portion of a patient's body to the carriage. A pneumatic cylinder includes a cylinder housing attached to the support structure. The cylinder housing contains a piston and piston rod. The piston rod is attached to the carriage for moving the carriage along the longitudinal axis relative to the support structure when pressurized air is injected into the pneumatic cylinder. The piston has at least one pressure activated seal extending circumferentially around the piston for engagement with an inside surface of the cylinder housing. A bicycle-style hand pump fluidly connected to the pneumatic cylinder is provided for injecting pressurized air into the cylinder.
摘要翻译：便携式牵引装置适用于由气动气缸驱动的颈部或腰部牵引。便携式牵引装置包括具有纵向轴线的支撑结构和可沿着平行于纵向轴线的支撑结构的一部分滑动的托架。托架包括用于将患者身体的一部分可释放地限制在托架上的限制机构。气缸包括附接到支撑结构的气缸壳体。缸体包含活塞和活塞杆。当压缩空气被注入到气缸中时，活塞杆连接到滑架上，用于使托架相对于支撑结构沿着纵向轴线移动。活塞具有至少一个沿活塞周向延伸的压力活化密封件，用于与气缸壳体的内表面接合。流体连接到气缸的自行车式手泵设置用于将加压空气注入气缸。

5. 发明授权

US08083705B2 Portable cervical traction device 有权
标题翻译：便携式颈椎牵引装置
公开(公告)号：US08083705B2
公开(公告)日：2011-12-27
申请号：US12319320
申请日：2009-01-05
申请人： H. Duane Saunders , Mark R. Stultz
发明人： H. Duane Saunders , Mark R. Stultz
IPC分类号： A61F5/00
CPC分类号： A61F5/04 , A61H1/0222 , A61H1/0296 , A61H2201/0157 , A61H2201/0161 , A61H2201/0192 , A61H2201/1246 , A61H2201/1607 , A61H2201/1628 , A61H2201/1664 , A61H2201/5053 , A61H2203/0456
摘要： Low-cost, light weight portable cervical traction or spinal decompression devices for home use by a patient. A carriage is slidable along a portion of a support structure parallel to a longitudinal axis. The carriage includes a restraining mechanism adapted to releasably restrain a portion of a patient's body to the carriage. The pneumatic traction force generating apparatus is operatively coupled to move the carriage relative to the support structure when in a pressurized state. The pneumatic traction force generating apparatus is adapted to maintain a generally static traction force during a treatment period when in the pressurized state without additional pressurized air being supplied. A hand pump operated by the patient is fluidly connected to the pneumatic traction force generating apparatus to inject pressurized air. A pressure relief mechanism operated by the patient is adapted to release pressure from the pneumatic traction force generating apparatus.
摘要翻译：低成本，重量轻的便携式颈椎牵引或脊柱减压装置，供患者家庭使用。滑架可沿平行于纵向轴线的支撑结构的一部分滑动。托架包括适于将患者身体的一部分可释放地限制在托架上的约束机构。当处于加压状态时，气动牵引力产生装置可操作地联接以相对于支撑结构移动滑架。气动牵引力发生装置适于在处于加压状态的处理期间保持大体静态的牵引力，而不需要额外的加压空气供给。由患者操作的手动泵流体地连接到气动牵引力产生装置以注入加压空气。由患者操作的减压机构适于从气动牵引力产生装置释放压力。

6. 发明申请

US20090118657A1 Portable cervical traction device 有权
标题翻译：便携式颈椎牵引装置
公开(公告)号：US20090118657A1
公开(公告)日：2009-05-07
申请号：US12319320
申请日：2009-01-05
申请人： H. Duane Saunders , Mark R. Stultz
发明人： H. Duane Saunders , Mark R. Stultz
IPC分类号： A61F5/00
CPC分类号： A61F5/04 , A61H1/0222 , A61H1/0296 , A61H2201/0157 , A61H2201/0161 , A61H2201/0192 , A61H2201/1246 , A61H2201/1607 , A61H2201/1628 , A61H2201/1664 , A61H2201/5053 , A61H2203/0456
摘要： Low-cost, light weight portable cervical traction or spinal decompression devices for home use by a patient. A carriage is slidable along a portion of a support structure parallel to a longitudinal axis. The carriage includes a restraining mechanism adapted to releasably restrain a portion of a patient's body to the carriage. The pneumatic traction force generating apparatus is operatively coupled to move the carriage relative to the support structure when in a pressurized state. The pneumatic traction force generating apparatus is adapted to maintain a generally static traction force during a treatment period when in the pressurized state without additional pressurized air being supplied. A hand pump operated by the patient is fluidly connected to the pneumatic traction force generating apparatus to inject pressurized air. A pressure relief mechanism operated by the patient is adapted to release pressure from the pneumatic traction force generating apparatus.
摘要翻译：低成本，重量轻的便携式颈椎牵引或脊柱减压装置，供患者家庭使用。滑架可沿平行于纵向轴线的支撑结构的一部分滑动。托架包括适于将患者身体的一部分可释放地限制在托架上的约束机构。当处于加压状态时，气动牵引力产生装置可操作地联接以相对于支撑结构移动滑架。气动牵引力发生装置适于在处于加压状态的处理期间保持大体静态的牵引力，而不需要额外的加压空气供给。由患者操作的手动泵流体地连接到气动牵引力产生装置以注入加压空气。由患者操作的减压机构适于从气动牵引力产生装置释放压力。

7. 发明授权

US07083593B2 Programmable implantable pump with accessory reservoirs and multiple independent lumen catheter 有权
公开(公告)号：US07083593B2
公开(公告)日：2006-08-01
申请号：US10099060
申请日：2002-03-15
申请人： Mark R. Stultz
发明人： Mark R. Stultz
IPC分类号： A61M31/00
CPC分类号： A61M5/14276 , A61M5/1452 , A61M5/16827 , A61M5/1723 , A61M2005/1405 , A61M2005/14208 , A61M2205/3523 , A61M2209/045
摘要： An implantable pump system includes: (1) an implantable pump having separate chambers or reservoirs, at least one of which is coupled to the pump so as to allow a programmable rate of delivery of the medication stored in the pump chamber or reservoir, the other chambers or reservoirs of which are at least capable of delivery of a bolus via a pressurized, and potentially independently programmable chamber or pumping mechanism; (2) a patient controller that enables the actuation of the pump so as to administer a bolus or programmed rate of the first, second, third, . . . or nth medication contained in the independent chambers or reservoirs coupled to the pump; and (3) a catheter having two or more reservoir-specific inlet ports directed into respective lumens of the catheter. In one embodiment, the distal tips of the respective lumens may be directed to different sites within the patient's body, thereby allowing site specific and independent delivery of the medications stored in the respective pump chambers or reservoirs to be administered to different body sites at independently controlled times and rates. In another embodiment, the distal tips of the respective lumens are directed, more or less, to the same body site or tissue region, thereby providing for the independent delivery of multiple medications to the same regions at independently controlled times and rates.

8. 发明授权

US06899690B2 Portable cervical traction device 有权
标题翻译：便携式颈椎牵引装置
公开(公告)号：US06899690B2
公开(公告)日：2005-05-31
申请号：US10320589
申请日：2002-12-16
申请人： H. Duane Saunders , Mark R. Stultz
发明人： H. Duane Saunders , Mark R. Stultz
IPC分类号： A61F5/04 , A61F5/00
CPC分类号： A61F5/04 , A61H1/0222 , A61H1/0296 , A61H2201/0157 , A61H2201/0161 , A61H2201/0192 , A61H2201/1246 , A61H2201/1607 , A61H2201/1628 , A61H2201/1664 , A61H2201/5053 , A61H2203/0456
摘要： A portable traction device suitable for cervical traction powered by a pneumatic cylinder. The portable traction device includes a support structure having a longitudinal axis and a carriage slidable along a portion of the support structure parallel to the longitudinal axis. The carriage including restraining mechanism for releasably restraining a portion of a patient's body to the carriage. A pneumatic cylinder includes a cylinder housing attached to the support structure. The cylinder housing contains a piston and piston rod. The piston rod is attached to the carriage for moving the carriage along the longitudinal axis relative to the support structure when pressurized air is injected into the pneumatic cylinder. The piston has at least one pressure activated seal extending circumferentially around the piston for engagement with an inside surface of the cylinder housing. A bicycle-style hand pump fluidly connected to the pneumatic cylinder is provided for injecting pressurized air into the cylinder.
摘要翻译：适用于由气动气缸动力的颈部牵引的便携式牵引装置。便携式牵引装置包括具有纵向轴线的支撑结构和可沿着平行于纵向轴线的支撑结构的一部分滑动的托架。托架包括用于将患者身体的一部分可释放地限制在托架上的限制机构。气缸包括附接到支撑结构的气缸壳体。缸体包含活塞和活塞杆。当压缩空气被注入到气缸中时，活塞杆连接到滑架上，用于使托架相对于支撑结构沿着纵向轴线移动。活塞具有至少一个沿活塞周向延伸的压力活化密封件，用于与气缸壳体的内表面接合。流体连接到气缸的自行车式手泵设置用于将加压空气注入气缸。

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