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1. 发明申请

US20050113902A1 Rapid-exchange delivery systems for self-expanding stents 有权
标题翻译：用于自扩张支架的快速交换输送系统
公开(公告)号：US20050113902A1
公开(公告)日：2005-05-26
申请号：US10720032
申请日：2003-11-20
申请人： Timothy Geiser , Charles Peterson , Andy Denison , Stephanie Klocke , Samir Patel , Joanna Lubas , Joanne Lumauig , Kathy Lind , Keif Fitzgerald
发明人： Timothy Geiser , Charles Peterson , Andy Denison , Stephanie Klocke , Samir Patel , Joanna Lubas , Joanne Lumauig , Kathy Lind , Keif Fitzgerald
IPC分类号： A61F2/84 , A61L29/00 , A61M25/00 , A61F2/06
CPC分类号： A61F2/95 , A61F2/966 , A61M2025/0183
摘要： A catheter assembly is provided having an inner member and an outer member extending along a longitudinal axis, the inner member and the outer member having a coaxial configuration and dimensioned for relative axial movement. The outer member may include an anti rotation member adapted to engage with a longitudinal slot formed on the inner member so as to maintain rotational alignment between inner member and outer member. The inner member can be made with a proximal portion made from a tubing such as hypotubing or a coil tubing. The inner member also may be made with a proximal portion made with a support mandrel. A coil tubing can be utilized to form the guide wire receiving member which is attached to the inner member.
摘要翻译：提供导管组件，其具有内部构件和沿着纵向轴线延伸的外部构件，内部构件和外部构件具有同轴构造并且被设计成用于相对轴向移动。外部构件可以包括防旋转构件，其适于与形成在内部构件上的纵向狭槽接合，以便保持内部构件和外部构件之间的旋转对准。内部构件可以由具有诸如假面或管线管的管子制成的近端部分制成。内部构件也可以由具有支撑心轴的近端部分制成。可以使用线圈管来形成附接到内部构件的导丝接收构件。

2. 发明授权

US07867271B2 Rapid-exchange delivery systems for self-expanding stents 有权
标题翻译：用于自扩张支架的快速交换输送系统
公开(公告)号：US07867271B2
公开(公告)日：2011-01-11
申请号：US10720032
申请日：2003-11-20
申请人： Timothy A. Geiser , Charles R. Peterson , Andy Denison , Stephanie Klocke , Samir Patel , Joanna Lubas , Joanne Lumauig , Kathy Lind , Keif Fitzgerald
发明人： Timothy A. Geiser , Charles R. Peterson , Andy Denison , Stephanie Klocke , Samir Patel , Joanna Lubas , Joanne Lumauig , Kathy Lind , Keif Fitzgerald
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/966 , A61M2025/0183
摘要： A catheter assembly is provided having an inner member and an outer member extending along a longitudinal axis, the inner member and the outer member having a coaxial configuration and dimensioned for relative axial movement. The outer member may include an anti rotation member adapted to engage with a longitudinal slot formed on the inner member so as to maintain rotational alignment between inner member and outer member. The inner member can be made with a proximal portion made from a tubing such as hypotubing or a coil tubing. The inner member also may be made with a proximal portion made with a support mandrel. A coil tubing can be utilized to form the guide wire receiving member which is attached to the inner member.
摘要翻译：提供导管组件，其具有内部构件和沿着纵向轴线延伸的外部构件，内部构件和外部构件具有同轴构造并且被设计成用于相对轴向移动。外部构件可以包括防旋转构件，其适于与形成在内部构件上的纵向狭槽接合，以便保持内部构件和外部构件之间的旋转对准。内部构件可以由具有诸如假面或管线管的管子制成的近端部分制成。内部构件也可以由具有支撑心轴的近端部分制成。可以使用线圈管来形成附接到内部构件的导丝接收构件。

3. 发明申请

US20050228439A1 Delivery and recovery system for embolic protection system 审中-公开
标题翻译：用于栓塞保护系统的交付和恢复系统
公开(公告)号：US20050228439A1
公开(公告)日：2005-10-13
申请号：US11139462
申请日：2005-05-26
申请人： Christopher Andrews , William Boyle , Sergio Correa , Andy Denison , Benjamin Huter , Scott Huter , Brad Jordan , Paul Muller , Paul Neale , Samir Patel , Richard Stack
发明人： Christopher Andrews , William Boyle , Sergio Correa , Andy Denison , Benjamin Huter , Scott Huter , Brad Jordan , Paul Muller , Paul Neale , Samir Patel , Richard Stack
IPC分类号： A61F2/01 , A61F2/06 , A61M29/00
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A system for enabling the insertion and removal of an embolic protection device, for capturing and retaining embolic debris which can be created during the performance of a therapeutic interventional procedure in a stenosed or occluded region of a blood vessel. The system, in an embodiment thereof, is capable of enabling at least one operator to control the delivery and removal of an embolic protection device to a position in a patient's vasculature distal to an interventional procedure site, to enable the exchange of the delivery and recovery system. The system, in another embodiment thereof, includes a delivery system and a recovery system which are capable of enabling the delivery and recovery of an embolic protection device so as to maintain a clinically acceptable profile and flexibility through the patient's vasculature.
摘要翻译：一种能够插入和移除栓塞保护装置的系统，用于捕获和保持在血管狭窄或阻塞区域中执行治疗性介入手术期间可产生的栓塞残留物。该系统在其一个实施例中能够使至少一个操作者能够将栓塞保护装置的输送和移除控制到远离介入手术部位的患者脉管系统中的位置，以实现交付和恢复的交换系统。该系统在其另一个实施例中包括输送系统和恢复系统，其能够实现栓塞保护装置的输送和恢复，以便通过患者的脉管系统保持临床可接受的特征和灵活性。

4. 发明申请

US20150175526A2 THE NOVEL REFERENCE MARKERS FOR FESOTERODINE FUMARATE 审中-公开
标题翻译： FESOTERODINE FUMARATE的新参考标记
公开(公告)号：US20150175526A2
公开(公告)日：2015-06-25
申请号：US14370577
申请日：2013-01-08
申请人： Venkatraman Jayaraman , Sundara Kalyana Balaji , Samir Patel , Thakor Indrajit , Viral Parekh , Mahesh Ladani , Chetan Patil , Ronak Patel , Darshan Parmar , Venkatraman Jayaraman , Sundara Kalyana Balaji , Samir Patel , Thakor Indrajit , Viral Parekh , Mahesh Ladani , Chetan Patil , Ronak Patel , Darshan Parmar
发明人： Venkatraman Jayaraman , Sundara Kalyana Balaji , Samir Patel , Thakor Indrajit , Viral Parekh , Mahesh Ladani , Chetan Patil , Ronak Patel , Darshan Parmar
IPC分类号： C07C219/22 , B65D81/26 , A61J1/10 , B65D81/20 , C07C217/48 , C07C213/06
CPC分类号： C07C219/22 , A61J1/10 , A61K31/222 , B65D81/2023 , B65D81/264 , C07C213/06 , C07C213/10 , C07C217/48 , C07C219/28 , G01N33/15
摘要： The present invention relates to the new impurities of Fesoterodine, Fesoterodine symmetric dimer impurity and asymmetric dimer impurity, process for preparing and isolating thereof. The invention also deals with analytical standards and analytical methods used for the control of the production process and final quality of Fesoterodine.
摘要翻译：本发明涉及非索罗定，非索罗定对称二聚体杂质和不对称二聚体杂质的新杂质，其制备和分离方法。本发明还涉及用于控制生产过程和费斯托罗定最终质量的分析标准和分析方法。

5. 发明申请

US20070213686A1 System and method for prevention of radiocontrast induced nephropathy 审中-公开
标题翻译：用于预防放射性对照诱导的肾病的系统和方法
公开(公告)号：US20070213686A1
公开(公告)日：2007-09-13
申请号：US11347008
申请日：2006-02-03
申请人： Vandana Mathur , Craig Ball , Jeffrey Elkins , Harry Goodson , Samir Patel
发明人： Vandana Mathur , Craig Ball , Jeffrey Elkins , Harry Goodson , Samir Patel
IPC分类号： A61B19/00
CPC分类号： A61M5/1723 , A61B90/00 , A61B2017/22082 , A61M5/007 , A61M25/0068 , A61M2005/1403 , A61M2025/0037 , A61M2025/1045
摘要： An apparatus and method particularly useful in treatments and therapies directed at the kidneys such as the prevention of radiocontrast nephropathy (RCN) arising from diagnostic procedures using iodinated contrast materials. A series of treatment schemes are provided based upon local therapeutic agent delivery to the kidneys that can be used as a prophylactic treatment for patients undergoing interventional procedures that have been identified as being at an elevated risk for developing RCN as well as for low risk patients. The methods may include pre-exposure and post contrast exposure treatments alone or in combination with the local delivery of therapeutic agents to the kidneys. Among the agents identified for such treatments are normal saline and the vasodilators papaverine and fenoldopam mesylate and appropriate dosing is provided.
摘要翻译：特别适用于针对肾脏的治疗和疗法的装置和方法，例如使用碘化造影剂的诊断程序引起的放射性对比肾病（RCN）的预防。提供了一系列基于局部治疗剂递送到肾脏的治疗方案，其可用作对已经被鉴定为发展RCN和低风险患者的高风险的介入手术的患者的预防性治疗。所述方法可以包括单独的暴露前曝光和造影后处理，或与治疗剂局部递送到肾脏的方法。鉴定用于这种治疗的药剂是生理盐水，并且提供了血管扩张剂罂粟碱和甲磺酸芬诺多胺，并提供适当的给药。

6. 外观设计

USD403110S Ridged flamingo bill hair clip 失效
公开(公告)号：USD403110S
公开(公告)日：1998-12-22
申请号：US75474
申请日：1997-06-23
申请人： Samir Patel
设计人： Samir Patel

7. 发明申请

US20110110932A1 COMBINATION TREATMENT FOR OCULAR DISEASES 审中-公开
标题翻译：眼部疾病的组合治疗
公开(公告)号：US20110110932A1
公开(公告)日：2011-05-12
申请号：US12768605
申请日：2010-04-27
申请人： Samir Patel
发明人： Samir Patel
IPC分类号： A61K39/395 , A61K38/18 , A61K31/7088
CPC分类号： A61K38/17 , A61K31/7088 , A61K39/395 , A61K45/06 , A61K2039/507 , C07K16/22 , C07K16/2842 , C07K2317/73 , A61K2300/00
摘要： The invention provides compositions and methods for treating ocular disorders, such as angiogenesis-associated disorders, by administering a combination of an inhibitor of VEGF activity and an inhibitor of α5β1 integrin activity.
摘要翻译：本发明提供了通过施用VEGF活性抑制剂和α5和bgr1整联蛋白活性抑制剂的组合来治疗眼部疾病如血管生成相关疾病的组合物和方法。

8. 发明申请

US20080075150A1 Reverse link correlation filter in wireless communication systems 失效
标题翻译：无线通信系统中的反向链路相关滤波器
公开(公告)号：US20080075150A1
公开(公告)日：2008-03-27
申请号：US11901571
申请日：2007-09-17
申请人： Antoine Rouphael , John Hoffmann , George Nelson , Samir Patel , James Proctor , Daniel Riley
发明人： Antoine Rouphael , John Hoffmann , George Nelson , Samir Patel , James Proctor , Daniel Riley
IPC分类号： H04B1/69
CPC分类号： H04B1/707 , H04B1/7105 , H04B1/712 , H04B2201/70703 , H04B2201/70705 , H04B2201/7071
摘要： A single, common correlation filter (CF) core is provided in a receiver for recovery of data from received code division multiple access (CDMA) signals. Signals are received over CDMA channels with different data rates, where the received signals include user information such as pilot and data symbols that have been spread according to different despreading rates including tier 1, tier 2 and tier 3 rates, where tier 1 is the smallest despreading rate. The received signal is correlated at the smallest despreading rate in the correlation filter (CF) by time multiplexing delayed versions of the pseudorandom noise (PN) code. The correlated information is then demultiplexed and pilot-aided QPSK demodulated. The demodulated information is summed at the proper integer multiple of the tier 1 rate to achieve tier 2 and tier 3 despreading rates. According to an embodiment, the three strongest multipaths components in terms of the received power are selected in a window or time period for optimal information recovery.
摘要翻译：在接收机中提供单个公共相关滤波器（CF）核，用于从接收的码分多址（CDMA）信号中恢复数据。在具有不同数据速率的CDMA信道上接收信号，其中所接收的信号包括诸如导频和数据符号之类的用户信息，所述导频和数据符号根据不同的解扩速率（包括层1，层2和层3速率）进行扩展，其中层1是最小的解散率。接收到的信号通过伪随机噪声（PN）码的延迟版本的时间复用以相关滤波器（CF）中的最小解扩频率相关。然后将相关信息解复用并导频辅助QPSK解调。解调信息以1级速率的适当整数倍相加，以实现2级和3级解扩速率。根据实施例，在用于最佳信息恢复的窗口或时间段中选择关于接收功率的三个最强多径分量。

9. 发明申请

US20060069323A1 Systems and methods for bi-lateral guidewire cannulation of branched body lumens 审中-公开
标题翻译：分支体腔双向导丝套管的系统和方法
公开(公告)号：US20060069323A1
公开(公告)日：2006-03-30
申请号：US11233562
申请日：2005-09-22
申请人： Jeffrey Elkins , Harry Goodson , Aurelio Valencia , Richard Aboytes , Samir Patel
发明人： Jeffrey Elkins , Harry Goodson , Aurelio Valencia , Richard Aboytes , Samir Patel
IPC分类号： A61M25/00
CPC分类号： A61M25/0172 , A61M25/01 , A61M25/0105 , A61M25/0662 , A61M25/09
摘要： A system and method is provided that is adapted to allow for rapid cannulation of a guidewire into a branch lumen extending from a main lumen in a body of a patient, and in particular into two renal arteries extending from an abdominal aorta wall. A dual lumen catheter shaft delivers first and second pre-shaped guidewires to the location of the renal arteries in the aorta, such that the first and second pre-shaped guidewires self-cannulate within the renal arteries. Additional guidewires and/or interventional devices may be incorporated into the system and method for use with the catheter shaft, or over the two pre-shaped guidewires, to meet a particular need for a particular patient or intended procedure.
摘要翻译：提供了一种系统和方法，其适于允许将导丝快速插入到从患者体内的主腔延伸的分支腔中，特别是从腹主动脉壁延伸的两个肾动脉中。双腔导管轴将第一和第二预形状导丝导管到主动脉中肾动脉的位置，使得第一和第二预成形导丝在肾动脉内自我插管。额外的导线和/或介入装置可以并入用于导管轴或两个预成形导丝线上的系统和方法，以满足特定患者或预期程序的特定需要。

10. 发明申请

US20050267010A1 Bi-lateral local renal delivery for treating congestive heart failure and for BNP therapy 失效
标题翻译：用于治疗充血性心力衰竭和BNP治疗的双侧局部肾移植
公开(公告)号：US20050267010A1
公开(公告)日：2005-12-01
申请号：US11129101
申请日：2005-05-13
申请人： Harry Goodson , Samir Patel , Craig Ball , Jeffrey Elkins
发明人： Harry Goodson , Samir Patel , Craig Ball , Jeffrey Elkins
IPC分类号： A61K38/17 , A61K38/22 , A61M25/00 , A61M25/04
CPC分类号： A61M25/0041 , A61K38/2242 , A61M25/0054 , A61M25/04 , A61M2025/0681 , A61M2210/1085
摘要： The invention relates to systems and methods for local renal delivery of agents to subjects that are at risk for congestive heart failure and other conditions. The invention encompasses devices for renal drug delivery and methods of use.
摘要翻译：本发明涉及用于将局部肾递送给患有充血性心力衰竭和其他病症风险的受试者的系统和方法。本发明包括用于肾药物递送的装置和使用方法。

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